DK200201813A - Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper - Google Patents

Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper Download PDF

Info

Publication number
DK200201813A
DK200201813A DK200201813A DKPA200201813A DK200201813A DK 200201813 A DK200201813 A DK 200201813A DK 200201813 A DK200201813 A DK 200201813A DK PA200201813 A DKPA200201813 A DK PA200201813A DK 200201813 A DK200201813 A DK 200201813A
Authority
DK
Denmark
Prior art keywords
mva
coding sequence
virus
expression cassette
derivative
Prior art date
Application number
DK200201813A
Other languages
English (en)
Inventor
Howley Paul
Leyrer Sonja
Original Assignee
Bavarian Nordic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bavarian Nordic As filed Critical Bavarian Nordic As
Priority to DK200201813A priority Critical patent/DK200201813A/da
Priority to KR10-2004-7018205A priority patent/KR20040108804A/ko
Priority to MXPA04011034A priority patent/MXPA04011034A/es
Priority to SI200330175T priority patent/SI1404852T1/sl
Priority to ES03732369T priority patent/ES2256747T3/es
Priority to CNB038106523A priority patent/CN1289682C/zh
Priority to DK03732369T priority patent/DK1404852T3/da
Priority to EA200401505A priority patent/EA009525B1/ru
Priority to AU2003240243A priority patent/AU2003240243B2/en
Priority to AT03732369T priority patent/ATE313641T1/de
Priority to NZ536500A priority patent/NZ536500A/en
Priority to JP2004506499A priority patent/JP2005525821A/ja
Priority to CA002481783A priority patent/CA2481783A1/en
Priority to PL03372091A priority patent/PL372091A1/xx
Priority to EP03732369A priority patent/EP1404852B1/en
Priority to US10/514,922 priority patent/US20060029619A1/en
Priority to BR0310020-0A priority patent/BR0310020A/pt
Priority to PCT/EP2003/005046 priority patent/WO2003097844A1/en
Priority to DE60302848T priority patent/DE60302848T2/de
Priority to IL16417903A priority patent/IL164179A0/xx
Publication of DK200201813A publication Critical patent/DK200201813A/da
Priority to NO20045315A priority patent/NO20045315L/no
Priority to HK05108709A priority patent/HK1076835A1/xx

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Description

Krav: 1. Rekombinant Modificeret Vaccinia Virus Ankara (MVA) som i det virale genom omfatter en ekspressions kassette hvilket igen omfatter ko-koppe ATI promotoren eller en afledt deraf og en kodende sekvens, hvori ekspressionen af den kodende sekvens er reguleret af denne promotor. 2. Rekombinant MVA som ovenover, hvor ATI promotoren har samme sekvens som SEQ ID: No. 1. 3. Rekombinant MVA ifølge krav 1, hvor den afledte af ATI promotoren er udvalgt fra (i) subsekvenser af sekvensen ifølge SEQ ID: No. 1 og (ii) sekvenser der har en eller flere nukleotid substitutioner, deleteringer, og /eller indsættelser i forhold til sekvensen ifølge SEQ ID: No. I eller i forhold til en subsekvens deraf, hvori denne subsekvens og sekvenser respektivt stadig er aktive som promotorer i MVA. 4. Rekombinant MVA ifølge ethver af kravene 1-3, hvor MVA er udvalgt fra stammen MVA-BN deponeret hos European Collection of Cell Cultures (ECACC) under nummer V00083008 eller en afledt deraf og stamme MVA 575 deponeret hos ECACC under nummer V00120707. 5. Rekombinant MVA ifølge ethvert af kravene 1 -4, hvor den kodende sekvens koder for mindst et antigen, antigenisk peptid og/eller et terapeteutisk stof. 6. Rekombinant MVA ifolgc ethvert af kravene 1 til 5 som vaccine eller medikament. 7. Vaccine eller farmaceutisk komposition der omfatter en rekombinant MVA ifølge ethvert af kravene 1-5. 8. Brug af rekombinant MVA ifølge ethvert af kravene 1-5 til udarbejdelse af en vaccine eller et medikament. 9. En celle der indeholde virussen ifølge ethvert af kravene 1-5. 10. Brugen af ko-koppe ATI promotoren eller en afledt deraf som defineret ifølge ethvert af kravene 1-5 til ekspression af kodende sekvenser i MVA.
DK200201813A 2002-05-16 2002-11-25 Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper DK200201813A (da)

Priority Applications (22)

Application Number Priority Date Filing Date Title
DK200201813A DK200201813A (da) 2002-11-25 2002-11-25 Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper
JP2004506499A JP2005525821A (ja) 2002-05-16 2003-05-14 牛痘ａｔｉプロモーターを用いた変異ワクシニアウイルスアンカラ中の遺伝子の発現
CA002481783A CA2481783A1 (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter
MXPA04011034A MXPA04011034A (es) 2002-05-16 2003-05-14 Expresion de los genes en el virus de la vacuna de ankara modificada, usando el promotor ati de viruela.
ES03732369T ES2256747T3 (es) 2002-05-16 2003-05-14 Expresion de genes en el virus de la vacuna modificado, usando el promotor ati de la viruela de la vaca.
CNB038106523A CN1289682C (zh) 2002-05-16 2003-05-14 通过使用牛痘ati启动子表达改良的安卡拉痘苗病毒中的基因
DK03732369T DK1404852T3 (da) 2002-05-16 2003-05-14 Ekspression af gener i modificeret vacciniavirus Ankara ved anvendelse af kokoppe-ATI-promotoren
EA200401505A EA009525B1 (ru) 2002-05-16 2003-05-14 Рекомбинантный модифицированный вирус осповакцины ankara, содержащий ati-промотор вируса коровьей оспы, и способы применения вируса и промотора
AU2003240243A AU2003240243B2 (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus Ankara by using the cowpox ATI promoter
PL03372091A PL372091A1 (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter
NZ536500A NZ536500A (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus ankara by using the cowpox ATI promoter
KR10-2004-7018205A KR20040108804A (ko) 2002-05-16 2003-05-14 우두 ａｔｉ 프로모터를 사용하는 것에 의한 변형백시니아 바이러스 안카라에서 유전자의 발현
SI200330175T SI1404852T1 (sl) 2002-05-16 2003-05-14 Ekspresija genov v modularnem vakcinija virusa Ankara z uporabo ATI promotorja kravjih ospic
AT03732369T ATE313641T1 (de) 2002-05-16 2003-05-14 Expression von genen im modifizierten vaccinia virus ankara durch verwendung eines cowpox ati promoter
EP03732369A EP1404852B1 (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter
US10/514,922 US20060029619A1 (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter
BR0310020-0A BR0310020A (pt) 2002-05-16 2003-05-14 Expressão de genes no vìrus da vacìnia modificado ancara por uso do promotor de ati de vacìnia
PCT/EP2003/005046 WO2003097844A1 (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter
DE60302848T DE60302848T2 (de) 2002-05-16 2003-05-14 Expression von genen im modifizierten vaccinia virus ankara durch verwendung eines cowpox ati promoter
IL16417903A IL164179A0 (en) 2002-05-16 2003-05-14 Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter
NO20045315A NO20045315L (no) 2002-05-16 2004-12-03 Ekspresjon av gener i Modifisert Vacciniavirus Ankara ved a bruke kukoppe ATI-promoteren
HK05108709A HK1076835A1 (en) 2002-05-16 2005-09-30 Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK200201813A DK200201813A (da) 2002-11-25 2002-11-25 Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper

Publications (1)

Publication Number Publication Date
DK200201813A true DK200201813A (da) 2004-05-26

Family

ID=32479652

Family Applications (1)

Application Number Title Priority Date Filing Date
DK200201813A DK200201813A (da) 2002-05-16 2002-11-25 Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper

Country Status (1)

Country Link
DK (1) DK200201813A (da)

Similar Documents

Publication Publication Date Title
JP6818797B2 (ja) 強靭なｔ細胞用のｐｒ１３．５プロモータ及び抗体応答
JP6130876B2 (ja) 複製欠損性組換えウイルスワクチン中の抗原に対する細胞傷害性ｔ細胞応答に有利である反復ワクチン接種と組み合わされた最適化初期−後期プロモーター
US7189536B2 (en) Modified vaccinia ankara virus variant
JP4895505B2 (ja) 変異ワクシニアウイルスアンカラ（ｍｖａ）ゲノム中の挿入部位としての遺伝子間領域
US10111946B2 (en) Poxviral vectors for low antibody response after a first priming immunization
EP2627774B1 (en) Recombinant modified vaccinia virus ankara (mva) influenza vaccine
CN101142319B (zh) 基于使用修饰安卡拉痘苗病毒的疫苗
MXPA04011034A (es) Expresion de los genes en el virus de la vacuna de ankara modificada, usando el promotor ati de viruela.
EP1594970A1 (en) Recombinant mva and method for generation thereof
WO2023077147A2 (en) T-cell vaccines for patients with reduced humoral immunity
WO2004024756A2 (en) Orthopoxvirus antigens and use thereof
DK200201813A (da) Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper
EP1398380A1 (en) Orthopoxvirus antigens and use thereof
NL2014148B1 (en) Combination vaccine for camelids.
CN113227360A (zh) 具有新型流感病毒来源的血凝素蛋白基因的DIs株来源的重组牛痘病毒

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment