DK155662C - Fremgangsmaade til fremstilling af alfa-6-desoxy-5-hydroxytetracyclin ved hydrogenering af den tilsvarende 6-methylenforbindelse i naervaer af rhodiummetal - Google Patents

Fremgangsmaade til fremstilling af alfa-6-desoxy-5-hydroxytetracyclin ved hydrogenering af den tilsvarende 6-methylenforbindelse i naervaer af rhodiummetal

Info

Publication number
DK155662C
DK155662C DK193874A DK193874A DK155662C DK 155662 C DK155662 C DK 155662C DK 193874 A DK193874 A DK 193874A DK 193874 A DK193874 A DK 193874A DK 155662 C DK155662 C DK 155662C
Authority
DK
Denmark
Prior art keywords
hydrogeneration
hydroxytetracycline
desoxy
similar
present
Prior art date
Application number
DK193874A
Other languages
Danish (da)
English (en)
Other versions
DK155662B (da
Inventor
Jr Thomas Arthur Morris
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26997777&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK155662(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of DK155662B publication Critical patent/DK155662B/da
Application granted granted Critical
Publication of DK155662C publication Critical patent/DK155662C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
DK193874A 1973-04-20 1974-04-08 Fremgangsmaade til fremstilling af alfa-6-desoxy-5-hydroxytetracyclin ved hydrogenering af den tilsvarende 6-methylenforbindelse i naervaer af rhodiummetal DK155662C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35308473A 1973-04-20 1973-04-20
US35308473 1973-04-20
US42120673 1973-12-03
US05/421,206 US3954862A (en) 1973-04-20 1973-12-03 Process for producing α-6-deoxytetracyclines

Publications (2)

Publication Number Publication Date
DK155662B DK155662B (da) 1989-05-01
DK155662C true DK155662C (da) 1989-10-09

Family

ID=26997777

Family Applications (1)

Application Number Title Priority Date Filing Date
DK193874A DK155662C (da) 1973-04-20 1974-04-08 Fremgangsmaade til fremstilling af alfa-6-desoxy-5-hydroxytetracyclin ved hydrogenering af den tilsvarende 6-methylenforbindelse i naervaer af rhodiummetal

Country Status (30)

Country Link
US (1) US3954862A (no)
JP (1) JPS5710863B2 (no)
AR (1) AR200521A1 (no)
AT (1) AT333954B (no)
AU (1) AU461511B2 (no)
BG (1) BG25070A3 (no)
CA (1) CA1011736A (no)
CH (1) CH589044A5 (no)
CS (2) CS235092B2 (no)
DD (1) DD114404A5 (no)
DE (1) DE2418499C2 (no)
DK (1) DK155662C (no)
EG (1) EG11172A (no)
ES (1) ES425221A1 (no)
FI (1) FI60196C (no)
FR (1) FR2226389B1 (no)
GB (1) GB1458744A (no)
HK (1) HK28279A (no)
IE (1) IE40048B1 (no)
IL (1) IL44492A (no)
IN (1) IN138740B (no)
KE (1) KE2937A (no)
LU (1) LU69856A1 (no)
MY (1) MY7900242A (no)
NL (1) NL157893B (no)
NO (1) NO146596C (no)
PH (1) PH10555A (no)
RO (2) RO80170A (no)
SE (1) SE416645B (no)
YU (1) YU39303B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743699A (en) * 1982-01-19 1988-05-10 Plurichemie Anstalt Homogeneous catalytic system and a process for the preparation of same
USRE32535E (en) * 1982-01-19 1987-10-27 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6343554U (no) * 1986-09-05 1988-03-23
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
CA2044612A1 (en) * 1989-01-04 1990-07-05 George Krsek Process for the production of alpha-6-deoxytetracyclines
DE68900339D1 (de) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd Verfahren zur herstellung von alpha-6-deoxytetracyclinen.
DE102007003434A1 (de) 2007-01-23 2008-07-24 Jäger, Anton Reinigungsvorrichtung
CN105152961B (zh) * 2015-08-31 2017-07-11 河南师范大学 一种强力霉素中间体6‑次甲基土霉素的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (no) * 1960-05-23 1966-05-25
GB1418137A (en) * 1972-02-24 1975-12-17 Ankerfarm Spa Process for the preparation of alpha-6-deoxytetracyclines

Also Published As

Publication number Publication date
CS235092B2 (en) 1985-04-16
NO146596B (no) 1982-07-26
AT333954B (de) 1976-12-27
ATA292274A (de) 1976-04-15
YU85974A (en) 1982-05-31
ES425221A1 (es) 1976-05-16
FR2226389A1 (no) 1974-11-15
CH589044A5 (no) 1977-06-30
CS235053B2 (en) 1985-04-16
IN138740B (no) 1976-03-27
FI60196B (fi) 1981-08-31
NO146596C (no) 1982-11-03
LU69856A1 (no) 1974-11-21
AU461511B2 (en) 1975-05-29
IE40048L (en) 1975-06-03
RO80170A (ro) 1982-10-26
IL44492A0 (en) 1974-06-30
DD114404A5 (no) 1975-08-05
IL44492A (en) 1977-01-31
RO78908A (ro) 1982-08-17
YU39303B (en) 1984-10-31
FR2226389B1 (no) 1976-12-17
IE40048B1 (en) 1979-02-28
GB1458744A (en) 1976-12-15
BG25070A3 (en) 1978-07-12
NO741223L (no) 1974-10-22
DE2418499C2 (de) 1982-12-23
AR200521A1 (es) 1974-11-15
US3954862A (en) 1976-05-04
CA1011736A (en) 1977-06-07
DK155662B (da) 1989-05-01
JPS5710863B2 (no) 1982-03-01
NL7404666A (no) 1974-10-22
JPS49135961A (no) 1974-12-27
NL157893B (nl) 1978-09-15
AU6714374A (en) 1975-05-29
PH10555A (en) 1977-06-08
DE2418499A1 (de) 1974-11-07
EG11172A (en) 1977-01-31
MY7900242A (en) 1979-12-31
KE2937A (en) 1979-03-30
SE416645B (sv) 1981-01-26
FI60196C (fi) 1981-12-10
HK28279A (en) 1979-05-11

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Legal Events

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PUP Patent expired