DK153556C - Fremgangsmaade til fremstilling af estere af 9alfa-klor- eller -fluor-16alfa- eller -16beta-metyl-21-desoxyprednisoloner - Google Patents
Fremgangsmaade til fremstilling af estere af 9alfa-klor- eller -fluor-16alfa- eller -16beta-metyl-21-desoxyprednisolonerInfo
- Publication number
- DK153556C DK153556C DK129575A DK129575A DK153556C DK 153556 C DK153556 C DK 153556C DK 129575 A DK129575 A DK 129575A DK 129575 A DK129575 A DK 129575A DK 153556 C DK153556 C DK 153556C
- Authority
- DK
- Denmark
- Prior art keywords
- desoxyprednisolones
- 9alfa
- 16alfa
- fluoro
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
- C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK196776A DK146909C (da) | 1974-03-27 | 1976-05-03 | Fremgangsmaade til fremstilling af estere eller aetere af 16-metyl-9alfa-halogenprednisoloner |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT6163674 | 1974-03-27 | ||
| PT6163674 | 1974-03-27 | ||
| PT6163774 | 1974-03-27 | ||
| PT6163774 | 1974-03-27 | ||
| PT6163675 | 1975-03-10 | ||
| PT6163675 | 1975-03-10 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK129575A DK129575A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-09-28 |
| DK153556B DK153556B (da) | 1988-07-25 |
| DK153556C true DK153556C (da) | 1988-12-05 |
Family
ID=27354092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK129575A DK153556C (da) | 1974-03-27 | 1975-03-26 | Fremgangsmaade til fremstilling af estere af 9alfa-klor- eller -fluor-16alfa- eller -16beta-metyl-21-desoxyprednisoloner |
Country Status (8)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR890000664B1 (ko) * | 1981-10-19 | 1989-03-22 | 바리 안소니 뉴우샘 | 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법 |
| IT1285770B1 (it) | 1996-10-04 | 1998-06-18 | Nicox Sa | Composti corticoidei |
| CN102516348B (zh) * | 2011-11-10 | 2013-11-13 | 中国科学院上海有机化学研究所 | 一种16s-甲基-20s-羟基孕甾化合物、合成方法及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1070751A (en) * | 1964-01-28 | 1967-06-01 | Glaxo Lab Ltd | 17-esters of 17-hydroxy-21-desoxy-steroids |
| GB1139505A (en) * | 1965-06-23 | 1969-01-08 | Glaxo Lab Ltd | A process for the production of 17-‡-monoesters of 17-‡-hydroxy-20-keto-steroids |
| US3383394A (en) * | 1965-08-30 | 1968-05-14 | Schering Corp | Novel 17-acylating process and products thereof |
| CH481085A (de) * | 1965-08-30 | 1969-11-15 | Scherico Ltd | Verfahren zur Herstellung von 11B-Hydroxy-17 -alkanoyloxysteroiden der Pregnanreihe |
| BE788355A (fr) * | 1971-09-07 | 1973-03-05 | Merck Patent Gmbh | Esters de 9 alpha-fluoro-16-methylene-prednisolone |
-
1975
- 1975-03-26 CH CH392475A patent/CH622811A5/de not_active IP Right Cessation
- 1975-03-26 NZ NZ177056A patent/NZ177056A/xx unknown
- 1975-03-26 GB GB47940/77A patent/GB1511820A/en not_active Expired
- 1975-03-26 DK DK129575A patent/DK153556C/da not_active IP Right Cessation
- 1975-03-26 GB GB12608/75A patent/GB1510617A/en not_active Expired
- 1975-03-27 FR FR7509621A patent/FR2274309A1/fr active Granted
- 1975-03-27 BE BE154849A patent/BE827275A/xx not_active IP Right Cessation
- 1975-03-27 IE IE693/75A patent/IE41137B1/xx unknown
- 1975-03-27 IE IE2062/75A patent/IE41138B1/xx unknown
-
1978
- 1978-03-16 SE SE7803041A patent/SE440656B/sv not_active IP Right Cessation
-
1979
- 1979-10-22 CH CH946879A patent/CH625254A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1511820A (en) | 1978-05-24 |
| DK153556B (da) | 1988-07-25 |
| IE41138B1 (en) | 1979-10-24 |
| BE827275A (fr) | 1975-07-16 |
| CH622811A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-04-30 |
| DK129575A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-09-28 |
| CH625254A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-09-15 |
| SE440656B (sv) | 1985-08-12 |
| GB1510617A (en) | 1978-05-10 |
| IE41137B1 (en) | 1979-10-24 |
| IE41137L (en) | 1975-09-27 |
| NZ177056A (en) | 1978-09-20 |
| FR2274309A1 (fr) | 1976-01-09 |
| FR2274309B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-11-24 |
| SE7803041L (sv) | 1978-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |