DK1521752T3 - Makrocykliske forbindelser til behandling af cancer - Google Patents
Makrocykliske forbindelser til behandling af cancerInfo
- Publication number
- DK1521752T3 DK1521752T3 DK03763870T DK03763870T DK1521752T3 DK 1521752 T3 DK1521752 T3 DK 1521752T3 DK 03763870 T DK03763870 T DK 03763870T DK 03763870 T DK03763870 T DK 03763870T DK 1521752 T3 DK1521752 T3 DK 1521752T3
- Authority
- DK
- Denmark
- Prior art keywords
- cancer
- treatment
- macrocyclic compounds
- macrocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10232094A DE10232094A1 (de) | 2002-07-15 | 2002-07-15 | 5-Thiaepothilone und 15-disubstituierte Epothilone |
| DE10255660A DE10255660A1 (de) | 2002-11-28 | 2002-11-28 | Neue Makrocyclen zur Behandlung von Krebserkrankungen |
| PCT/EP2003/007664 WO2004007492A1 (en) | 2002-07-15 | 2003-07-15 | Novel macrocycles for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1521752T3 true DK1521752T3 (da) | 2009-06-22 |
Family
ID=30116646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03763870T DK1521752T3 (da) | 2002-07-15 | 2003-07-15 | Makrocykliske forbindelser til behandling af cancer |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7553859B2 (ja) |
| EP (1) | EP1521752B1 (ja) |
| JP (1) | JP4597667B2 (ja) |
| AT (1) | ATE423780T1 (ja) |
| AU (1) | AU2003252540B2 (ja) |
| CA (1) | CA2491943C (ja) |
| DE (1) | DE60326348D1 (ja) |
| DK (1) | DK1521752T3 (ja) |
| ES (1) | ES2323956T3 (ja) |
| WO (1) | WO2004007492A1 (ja) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004048372A1 (en) * | 2002-11-28 | 2004-06-10 | Morphochem Ag Komb Chemie | Thia-epothilone derivatives for the treatment of cancer |
| ES2501565T3 (es) | 2008-04-24 | 2014-10-02 | Bristol-Myers Squibb Company | Uso de epotilona D en el tratamiento de enfermedades asociadas a Tau incluyendo enfermedad de Alzheimer |
| EP2394640A1 (en) | 2010-05-21 | 2011-12-14 | MediGene AG | Improved liposomal formulations of lipophilic compounds |
| EP2708243A1 (en) | 2012-09-17 | 2014-03-19 | OntoChem GmbH | Receptor ligand linked cytotoxic molecules |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001064650A2 (en) * | 2000-03-01 | 2001-09-07 | Sloan-Kettering Institute For Cancer Research Center | Synthesis of epothilones, intermediates thereto and analogues thereof |
| WO2002000216A1 (en) * | 2000-06-28 | 2002-01-03 | Teva Pharmaceutical Industries Ltd. | Carvedilol |
| WO2004048372A1 (en) * | 2002-11-28 | 2004-06-10 | Morphochem Ag Komb Chemie | Thia-epothilone derivatives for the treatment of cancer |
-
2003
- 2003-07-15 DE DE60326348T patent/DE60326348D1/de not_active Expired - Lifetime
- 2003-07-15 WO PCT/EP2003/007664 patent/WO2004007492A1/en active Application Filing
- 2003-07-15 US US10/520,769 patent/US7553859B2/en not_active Expired - Fee Related
- 2003-07-15 AU AU2003252540A patent/AU2003252540B2/en not_active Ceased
- 2003-07-15 ES ES03763870T patent/ES2323956T3/es not_active Expired - Lifetime
- 2003-07-15 EP EP03763870A patent/EP1521752B1/en not_active Expired - Lifetime
- 2003-07-15 CA CA2491943A patent/CA2491943C/en not_active Expired - Fee Related
- 2003-07-15 DK DK03763870T patent/DK1521752T3/da active
- 2003-07-15 AT AT03763870T patent/ATE423780T1/de not_active IP Right Cessation
- 2003-07-15 JP JP2004520647A patent/JP4597667B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1521752B1 (en) | 2009-02-25 |
| AU2003252540B2 (en) | 2008-11-20 |
| CA2491943A1 (en) | 2004-01-22 |
| EP1521752A1 (en) | 2005-04-13 |
| JP4597667B2 (ja) | 2010-12-15 |
| AU2003252540A1 (en) | 2004-02-02 |
| DE60326348D1 (de) | 2009-04-09 |
| JP2005537263A (ja) | 2005-12-08 |
| WO2004007492A1 (en) | 2004-01-22 |
| CA2491943C (en) | 2012-06-19 |
| US7553859B2 (en) | 2009-06-30 |
| US20060004065A1 (en) | 2006-01-05 |
| ES2323956T3 (es) | 2009-07-28 |
| ATE423780T1 (de) | 2009-03-15 |
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