DK1507865T3 - Fröen som eventyrprins, en transposonvektor for overföring af gener i hvirveldyr - Google Patents

Fröen som eventyrprins, en transposonvektor for overföring af gener i hvirveldyr

Info

Publication number
DK1507865T3
DK1507865T3 DK03732512T DK03732512T DK1507865T3 DK 1507865 T3 DK1507865 T3 DK 1507865T3 DK 03732512 T DK03732512 T DK 03732512T DK 03732512 T DK03732512 T DK 03732512T DK 1507865 T3 DK1507865 T3 DK 1507865T3
Authority
DK
Denmark
Prior art keywords
transposon
selectable marker
integration system
gene
based dna
Prior art date
Application number
DK03732512T
Other languages
Danish (da)
English (en)
Inventor
Csaba Miskey
Zsuzsanna Izsvak
Zoltan Ivics
Ronald Plasterk
Original Assignee
Max Delbrueck Centrum
Netherland Cancer Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Delbrueck Centrum, Netherland Cancer Inst filed Critical Max Delbrueck Centrum
Application granted granted Critical
Publication of DK1507865T3 publication Critical patent/DK1507865T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/60—Vectors containing traps for, e.g. exons, promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
DK03732512T 2002-05-29 2003-05-30 Fröen som eventyrprins, en transposonvektor for overföring af gener i hvirveldyr DK1507865T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10224242A DE10224242A1 (de) 2002-05-29 2002-05-29 Frog Prince, ein Transposonvektor für den Gentransfer bei Wirbeltieren
PCT/EP2003/005707 WO2003100070A2 (fr) 2002-05-29 2003-05-30 Frog prince, un vecteur de transposons destine a transferer des genes dans des vertebres

Publications (1)

Publication Number Publication Date
DK1507865T3 true DK1507865T3 (da) 2008-10-13

Family

ID=29432501

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03732512T DK1507865T3 (da) 2002-05-29 2003-05-30 Fröen som eventyrprins, en transposonvektor for overföring af gener i hvirveldyr

Country Status (8)

Country Link
US (1) US20050241007A1 (fr)
EP (1) EP1507865B1 (fr)
JP (1) JP4493492B2 (fr)
AT (1) ATE401411T1 (fr)
AU (1) AU2003238444A1 (fr)
DE (2) DE10224242A1 (fr)
DK (1) DK1507865T3 (fr)
WO (1) WO2003100070A2 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8598328B2 (en) 2006-12-13 2013-12-03 National University Corporation Nagoya University Tol1 factor transposase and DNA introduction system using the same
HU0700675D0 (en) 2007-10-15 2007-12-28 Mta Tamogatott Kutatohelyek Ir Method for monitoring stem cell differentiation
EP2067402A1 (fr) 2007-12-07 2009-06-10 Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; Mutagenèse par élément transposable dans les cellules souches spermatogoniales
WO2010008564A2 (fr) * 2008-07-16 2010-01-21 Recombinetics Système de transposons d'adn de plie
WO2010008562A2 (fr) * 2008-07-16 2010-01-21 Recombinetics Procédés et matériaux pour produire des animaux transgéniques
WO2011106314A2 (fr) * 2010-02-25 2011-09-01 Advanced Liquid Logic, Inc. Procédé de fabrication de banques d'acide nucléique
US20110312001A1 (en) 2010-06-15 2011-12-22 Emile Nuwaysir Compendium of ready-built stem cell models for interrogation of biological response
CA2804595C (fr) 2010-07-07 2018-11-13 Cellular Dynamics International, Inc. Production de cellules endotheliales par programmation
CA2806858C (fr) 2010-08-04 2021-06-15 Cellular Dynamics International, Inc. Reprogrammation des lymphocytes b immortalises
EP2673358B1 (fr) 2011-02-08 2019-01-09 FUJIFILM Cellular Dynamics, Inc. Production de précurseurs hématopoïétiques obtenus par programmation
CA2841165A1 (fr) 2011-07-11 2013-01-17 Cellular Dynamics International, Inc. Procedes de reprogrammation cellulaire et d'ingenierie genomique
CN105229144A (zh) 2013-02-22 2016-01-06 细胞动力学国际有限公司 通过组合的遗传工程和化学工程经由正向编程产生肝细胞
WO2014132137A2 (fr) 2013-03-01 2014-09-04 Université De Genève Sélection de cellules transgéniques
US20170107486A1 (en) 2014-04-21 2017-04-20 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
DK3365435T3 (da) 2015-10-20 2021-04-06 Fujifilm Cellular Dynamics Inc Produktion af hæmatopoietiske prækursorceller med multi-afstamning med genetisk programmering
GB201518910D0 (en) 2015-10-26 2015-12-09 Rieke Packaging Systems Ltd Dispensers
WO2017096363A1 (fr) 2015-12-04 2017-06-08 Board Of Regents, The University Of Texas System Système rapporteur pour la détection et le ciblage de cellules activées
CA3038701A1 (fr) 2016-10-05 2018-04-12 FUJIFILM Cellular Dynamics, Inc. Procedes de differenciation dirigee de cellules souches pluripotentes en cellules immunes homozygotes hla
EP3523422A1 (fr) 2016-10-05 2019-08-14 FUJIFILM Cellular Dynamics, Inc. Génération de lignées matures à partir de cellules souches pluripotentes induites avec une interruption mecp2
JP7181219B2 (ja) 2017-04-18 2022-11-30 フジフィルム セルラー ダイナミクス，インコーポレイテッド 抗原特異的免疫エフェクター細胞
CN112105731A (zh) 2018-03-30 2020-12-18 日内瓦大学 微小rna表达构建体及其用途
US20220257796A1 (en) 2019-07-02 2022-08-18 Fred Hutchinson Cancer Research Center Recombinant ad35 vectors and related gene therapy improvements
JP2023537558A (ja) 2020-05-27 2023-09-04 アンチオン バイオサイエンシーズ エスアー 目的の抗原にｃａｒ ｔ細胞をリダイレクトするためのアダプター分子
CA3216719A1 (fr) 2021-05-03 2022-11-10 Astellas Institute For Regenerative Medicine Procedes de generation de cellules endotheliales corneennes matures
CA3217861A1 (fr) 2021-05-07 2022-11-10 Astellas Institute For Regenerative Medicine Procedes de generation d'hepatocytes matures
GB202206507D0 (en) 2022-05-04 2022-06-15 Antion Biosciences Sa Expression construct

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2280997C (fr) * 1997-03-11 2013-05-28 Perry B. Hackett Systeme transposon a base d'adn permettant d'introduire de l'acide nucleique dans l'adn d'une cellule
CA2309000A1 (fr) * 1997-11-13 1999-05-27 Regents Of The University Of Minnesota Systeme de transposon a base de tc1

Also Published As

Publication number Publication date
AU2003238444A8 (en) 2003-12-12
WO2003100070A2 (fr) 2003-12-04
ATE401411T1 (de) 2008-08-15
US20050241007A1 (en) 2005-10-27
DE60322214D1 (de) 2008-08-28
AU2003238444A1 (en) 2003-12-12
WO2003100070A3 (fr) 2004-12-09
JP2005527216A (ja) 2005-09-15
EP1507865A2 (fr) 2005-02-23
DE10224242A1 (de) 2003-12-11
EP1507865B1 (fr) 2008-07-16
JP4493492B2 (ja) 2010-06-30

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