DK1492404T3 - Nye spinosyndannende polyketidsyntaser - Google Patents

Nye spinosyndannende polyketidsyntaser

Info

Publication number
DK1492404T3
DK1492404T3 DK03713546T DK03713546T DK1492404T3 DK 1492404 T3 DK1492404 T3 DK 1492404T3 DK 03713546 T DK03713546 T DK 03713546T DK 03713546 T DK03713546 T DK 03713546T DK 1492404 T3 DK1492404 T3 DK 1492404T3
Authority
DK
Denmark
Prior art keywords
forming
polyketide synthases
new spin
spin
new
Prior art date
Application number
DK03713546T
Other languages
Danish (da)
English (en)
Inventor
Lesley S Sheehan
Christine J Martin
William A Vousden
Clive Waldron
Barrie Wilkinson
Paul R Graupner
Paul Lewer
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Application granted granted Critical
Publication of DK1492404T3 publication Critical patent/DK1492404T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Catching Or Destruction (AREA)
DK03713546T 2002-02-19 2003-02-19 Nye spinosyndannende polyketidsyntaser DK1492404T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35807502P 2002-02-19 2002-02-19
PCT/US2003/004998 WO2003070908A2 (en) 2002-02-19 2003-02-19 Novel spinosyn-producing polyketide synthases

Publications (1)

Publication Number Publication Date
DK1492404T3 true DK1492404T3 (da) 2012-04-23

Family

ID=27757699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03713546T DK1492404T3 (da) 2002-02-19 2003-02-19 Nye spinosyndannende polyketidsyntaser

Country Status (11)

Country Link
US (5) US20030225006A1 (es)
EP (1) EP1492404B1 (es)
JP (1) JP4765032B2 (es)
KR (1) KR101016561B1 (es)
CN (1) CN1633237B (es)
AU (2) AU2003217591B2 (es)
DK (1) DK1492404T3 (es)
ES (1) ES2375714T3 (es)
IL (3) IL163529A0 (es)
MX (1) MXPA04008071A (es)
WO (1) WO2003070908A2 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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MXPA04008071A (es) 2002-02-19 2004-11-26 Dow Agrosciences Llc Nuevas sintasas de poliquetida que producen espinosina.
GB0327720D0 (en) 2003-11-28 2003-12-31 Biotica Tech Ltd Erythromycins and process for their preparation
GB0417852D0 (en) 2004-08-11 2004-09-15 Biotica Tech Ltd Production of polyketides and other natural products
WO2007144786A2 (en) * 2006-05-26 2007-12-21 Entarco Sa The vapor-phase application of spinosyn for the control of pests, and formulations and products utilizing the same
KR20110069118A (ko) * 2008-09-22 2011-06-22 크리스틴 크리티코우 스피노신 방오 조성물, 이의 사용 방법 및 생물 오손 유기체의 부착으로부터 보호된 물품
CN102388059B (zh) * 2009-02-11 2015-03-04 陶氏益农公司 杀虫组合物
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions
MX2011010323A (es) * 2009-04-03 2011-12-16 Kroff Chemical Company Inc Composiciones, sistemas y metodos para desenmulsificación para desemulsificar y separar emulsiones acuosas.
EP2445506B1 (en) 2009-06-24 2014-12-31 Entarco SA The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
EP2272963A1 (en) * 2009-07-09 2011-01-12 LEK Pharmaceuticals d.d. Process for Preparation of Tacrolimus
BR112012028860A2 (pt) 2010-05-11 2020-09-01 Dow Agrosciences Llc cepas spnk.
CN101942425B (zh) * 2010-08-24 2012-06-20 北京农学院 与苯亚甲基丙酮合成相关的酶及其编码基因与应用
US20160184340A1 (en) 2010-12-22 2016-06-30 Christine Kritikou The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
ES2625504T3 (es) 2011-05-03 2017-07-19 Dow Agrosciences Llc Integración de genes en el cromosoma de Saccharopolyspora spinosa
US9404107B2 (en) 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
US9631195B2 (en) * 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
US10844415B2 (en) 2014-11-14 2020-11-24 Zhejiang Hisun Pharmaceutical Co., Ltd. Spinosad heterologous expression strain and construction method thereof and use
BR112018004313A2 (pt) 2015-09-03 2018-10-09 Agrimetis Llc derivados de espinosina
WO2018226893A2 (en) 2017-06-06 2018-12-13 Zymergen Inc. A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1117005A (en) 1978-03-07 1982-01-26 Patrick G. Feakins Animal ear-tags, their manufacture and their use
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
MA21697A1 (fr) 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.
WO1993013663A1 (en) 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
US5539089A (en) * 1991-11-08 1996-07-23 Dowelanco A83543 aglycones and pseudoglycones
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
CA2156194C (en) 1993-03-12 2008-01-08 Jon S. Mynderse New a83543 compounds and process for production thereof
CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
US6001981A (en) 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
EA001744B1 (ru) 1996-07-05 2001-08-27 Байотика Текнолоджи Лимитед (Gb) Новые эритромицины и способы их получения
JP3441899B2 (ja) 1996-11-01 2003-09-02 理化学研究所 完全長cDNAライブラリーの作成方法
CN100527958C (zh) 1997-12-23 2009-08-19 辛根塔参与股份公司 大环内酯在害虫防治中的应用
US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
DE19823397B4 (de) 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
GB9814006D0 (en) * 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
UA65624C2 (uk) 1998-07-02 2004-04-15 Елі Ліллі Енд Компані Препарат для догляду за волоссям (варіанти) та спосіб боротьби з педикульозним ураженням людини із застосуванням спінозину (варіанти)
GB9814622D0 (en) * 1998-07-06 1998-09-02 Biotica Tech Ltd Polyketides,their preparation,and materials for use therein
EP1117801B1 (en) * 1998-10-02 2006-11-29 Kosan Biosciences, Inc. Polyketide synthase enzymes and recombinant dna constructs therefor, for the production of compounds related to fk-506 and fk-520
DE19857967A1 (de) 1998-12-16 2000-06-21 Bayer Ag Wirkstoffkombinationen
DE19857966A1 (de) 1998-12-16 2000-06-21 Bayer Ag Wirkstoffkombinationen
CA2361040A1 (en) * 1999-01-27 2000-08-03 Kosan Biosciences, Inc. Synthesis of oligoketides
JP2000245457A (ja) * 1999-02-24 2000-09-12 Kitasato Inst:The エバーメクチンアグリコン合成酵素遺伝子
DE19913174A1 (de) 1999-03-24 2000-09-28 Bayer Ag Synergistische insektizide Mischungen
GB9912563D0 (en) * 1999-05-28 1999-07-28 Biotica Tech Ltd Polyketides and their synthesis
JP2003508050A (ja) * 1999-08-27 2003-03-04 バイエル アクチェンゲゼルシャフト スピノシン生合成の酵素活性をコードする核酸
DE60015161T2 (de) * 1999-09-13 2006-02-02 Dow Agrosciences Llc, Indianapolis Pestizide makrolide
AU2001279771A1 (en) * 2000-07-20 2002-02-05 Campina B.V. Carrier material for dry powder inhalation
GB0019986D0 (en) * 2000-08-14 2000-10-04 Biotica Tech Ltd Polyketides and their synthesis
TWI275592B (en) * 2001-03-21 2007-03-11 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
US6919464B1 (en) * 2001-03-21 2005-07-19 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
DE10135550A1 (de) * 2001-07-20 2003-01-30 Bayer Cropscience Ag Verfahren zum Herstellen von neuen Spinosyn-Derivaten
MXPA04008071A (es) * 2002-02-19 2004-11-26 Dow Agrosciences Llc Nuevas sintasas de poliquetida que producen espinosina.
WO2005109887A1 (en) * 2004-04-23 2005-11-17 Smart Metric, Inc. Smartcard with visual display

Also Published As

Publication number Publication date
WO2003070908A2 (en) 2003-08-28
US20060040877A1 (en) 2006-02-23
EP1492404A4 (en) 2010-03-17
KR101016561B1 (ko) 2011-02-22
IL163529A0 (en) 2005-12-18
US7626010B2 (en) 2009-12-01
IL200471A (en) 2015-09-24
US20110178036A1 (en) 2011-07-21
AU2003217591B2 (en) 2009-02-26
US8624009B2 (en) 2014-01-07
IL163529A (en) 2011-11-30
JP4765032B2 (ja) 2011-09-07
US20030225006A1 (en) 2003-12-04
CN1633237B (zh) 2010-05-26
WO2003070908A3 (en) 2004-10-28
IL200471A0 (en) 2011-07-31
CN1633237A (zh) 2005-06-29
US20100068785A1 (en) 2010-03-18
EP1492404B1 (en) 2011-12-28
JP2005520500A (ja) 2005-07-14
ES2375714T3 (es) 2012-03-05
MXPA04008071A (es) 2004-11-26
AU2009200685B2 (en) 2012-01-12
KR20040085201A (ko) 2004-10-07
AU2003217591A1 (en) 2003-09-09
AU2009200685A1 (en) 2009-03-12
US20140080777A1 (en) 2014-03-20
US9137992B2 (en) 2015-09-22
EP1492404A2 (en) 2005-01-05

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