DK147468C - Analogifremgangsmaade til fremstilling af 14-chlor- eller 13,14-didehydro-prostaglandinderivater - Google Patents
Analogifremgangsmaade til fremstilling af 14-chlor- eller 13,14-didehydro-prostaglandinderivaterInfo
- Publication number
- DK147468C DK147468C DK193573A DK193573A DK147468C DK 147468 C DK147468 C DK 147468C DK 193573 A DK193573 A DK 193573A DK 193573 A DK193573 A DK 193573A DK 147468 C DK147468 C DK 147468C
- Authority
- DK
- Denmark
- Prior art keywords
- prostagland
- didehydro
- chlor
- analogue
- ingredients
- Prior art date
Links
- 239000004615 ingredient Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2306372 | 1972-04-13 | ||
| IT2306372 | 1972-04-13 | ||
| IT2366272 | 1972-04-28 | ||
| IT2366272 | 1972-04-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK147468B DK147468B (da) | 1984-08-20 |
| DK147468C true DK147468C (da) | 1985-02-04 |
Family
ID=26328323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK193573A DK147468C (da) | 1972-04-13 | 1973-04-10 | Analogifremgangsmaade til fremstilling af 14-chlor- eller 13,14-didehydro-prostaglandinderivater |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US3935254A (hu) |
| JP (1) | JPS577148B2 (hu) |
| AT (1) | AT351177B (hu) |
| CA (1) | CA1016166A (hu) |
| CH (2) | CH599149A5 (hu) |
| CS (1) | CS174195B2 (hu) |
| DE (1) | DE2318785C2 (hu) |
| DK (1) | DK147468C (hu) |
| FR (2) | FR2187334B1 (hu) |
| GB (2) | GB1425962A (hu) |
| HK (1) | HK3277A (hu) |
| HU (1) | HU169182B (hu) |
| IL (1) | IL42223A (hu) |
| MY (1) | MY7700132A (hu) |
| NL (1) | NL182400C (hu) |
| NO (1) | NO143575C (hu) |
| SE (1) | SE406762B (hu) |
| SU (1) | SU656510A3 (hu) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4041064A (en) * | 1974-09-17 | 1977-08-09 | Carlo-Erba S.P.A. | 16-Methyl prost-5-en-13-ynoic acid derivatives |
| DK155317C (da) * | 1974-09-25 | 1989-08-14 | Erba Carlo Spa | 13,14-dehydro-prostaglandin-f2alfa-derivater til anvendelse i midler med abortfremkaldende aktivitet |
| US4169145A (en) * | 1974-09-25 | 1979-09-25 | Carlo Erba S.P.A. | ω-Nor-cycloalkyl-13,14-dehydro-prostaglandins |
| IT1053781B (it) * | 1974-09-25 | 1981-10-10 | Erba C S P A Ora Farmitalia | Omega nor cicloalcil 13.14 deidro prostaglandine |
| AU501803B2 (en) * | 1975-03-21 | 1979-06-28 | Farmitalia Carlo Erba S.P.A. | Fluoro-prostaglandins |
| US4029681A (en) * | 1976-02-13 | 1977-06-14 | The Upjohn Company | 13,14-Didehydro-PG analogs |
| US4058564A (en) * | 1976-07-26 | 1977-11-15 | The Upjohn Company | Aliphatic 2-decarboxy-2-hydroxymethyl-13,14-didehydro-PG compounds |
| US4207422A (en) * | 1976-07-26 | 1980-06-10 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-13,14-didehydro-PGA, PGD, and PGE compounds |
| US4140721A (en) * | 1976-07-26 | 1979-02-20 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-13,14-didehydro-17-phenyl-PGA, PGD and PGE compounds |
| DE2655004C3 (de) * | 1976-12-02 | 1980-06-19 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von bicyclischen Laktonen |
| JPS5662969A (en) * | 1979-10-26 | 1981-05-29 | Mitsubishi Gas Chem Co Inc | Preventing method for corrosion of metal surface |
| US4291175A (en) * | 1980-04-03 | 1981-09-22 | American Cyanamid Company | 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives |
| US4288630A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11,15-dihydroxy-prosten-1-ol-derivatives |
| US4288633A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives |
| US4310700A (en) | 1980-04-03 | 1982-01-12 | American Cyanamid Company | 1-Hydroxylmethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives |
| US4288632A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11,16-dihydroxy-prosten-1-ol derivatives |
| US4291174A (en) * | 1980-04-03 | 1981-09-22 | American Cyanamid Company | 1-Hydroxymethyl-15-hydroxy-prosten-1-ol derivatives |
| US4288629A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives |
| US4543353A (en) * | 1981-11-27 | 1985-09-24 | Farmitalia Carlo Erba S.P.A. | Ester and amide derivatives of 13,14-didehydro prostaglandins |
| CZ2015376A3 (cs) * | 2015-06-03 | 2016-12-21 | Univerzita Pardubice | Způsob přípravy intermediátu přípravy prostaglandinového derivátu alfaprostolu |
| CN110256385A (zh) * | 2019-07-10 | 2019-09-20 | 上海玉函化工有限公司 | 一种前列腺素类药物中间体的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3728382A (en) * | 1970-05-04 | 1973-04-17 | Upjohn Co | 15-methyl and 15-ethyl prostaglandin analogs |
| US3711515A (en) * | 1970-11-27 | 1973-01-16 | Upjohn Co | Tricyclic lactone alkene or alkenyne |
-
1973
- 1973-03-23 GB GB2731375A patent/GB1425962A/en not_active Expired
- 1973-03-23 GB GB1422273A patent/GB1425961A/en not_active Expired
- 1973-03-30 US US05/346,249 patent/US3935254A/en not_active Expired - Lifetime
- 1973-04-10 AT AT315173A patent/AT351177B/de not_active IP Right Cessation
- 1973-04-10 DK DK193573A patent/DK147468C/da not_active IP Right Cessation
- 1973-04-12 SU SU731919945A patent/SU656510A3/ru active
- 1973-04-12 CS CS2593A patent/CS174195B2/cs unknown
- 1973-04-12 CA CA168,551A patent/CA1016166A/en not_active Expired
- 1973-04-12 NO NO1537/73A patent/NO143575C/no unknown
- 1973-04-12 SE SE7305181A patent/SE406762B/xx unknown
- 1973-04-13 JP JP4204973A patent/JPS577148B2/ja not_active Expired
- 1973-04-13 HU HUEA128A patent/HU169182B/hu unknown
- 1973-04-13 CH CH424376A patent/CH599149A5/xx not_active IP Right Cessation
- 1973-04-13 FR FR7313538A patent/FR2187334B1/fr not_active Expired
- 1973-04-13 NL NLAANVRAGE7305222,A patent/NL182400C/xx not_active IP Right Cessation
- 1973-04-13 DE DE2318785A patent/DE2318785C2/de not_active Expired
- 1973-04-13 CH CH538273A patent/CH591441A5/xx not_active IP Right Cessation
- 1973-05-08 IL IL42223A patent/IL42223A/en unknown
-
1975
- 1975-02-05 US US05/547,247 patent/US4035392A/en not_active Expired - Lifetime
- 1975-08-26 FR FR7526314A patent/FR2279744A1/fr active Granted
- 1975-11-13 US US05/631,655 patent/US4021477A/en not_active Expired - Lifetime
- 1975-11-13 US US05/631,656 patent/US4035414A/en not_active Expired - Lifetime
-
1977
- 1977-01-20 HK HK32/77A patent/HK3277A/xx unknown
- 1977-12-30 MY MY132/77A patent/MY7700132A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH591441A5 (hu) | 1977-09-15 |
| SE406762B (sv) | 1979-02-26 |
| US4021477A (en) | 1977-05-03 |
| IL42223A (en) | 1977-01-31 |
| JPS4913145A (hu) | 1974-02-05 |
| FR2187334B1 (hu) | 1979-02-23 |
| HU169182B (hu) | 1976-10-28 |
| CA1016166A (en) | 1977-08-23 |
| AT351177B (de) | 1979-07-10 |
| MY7700132A (en) | 1977-12-31 |
| NL182400C (nl) | 1988-03-01 |
| JPS577148B2 (hu) | 1982-02-09 |
| FR2279744A1 (fr) | 1976-02-20 |
| SU656510A3 (ru) | 1979-04-05 |
| NO143575B (no) | 1980-12-01 |
| US4035414A (en) | 1977-07-12 |
| US3935254A (en) | 1976-01-27 |
| FR2279744B1 (hu) | 1979-02-02 |
| FR2187334A1 (hu) | 1974-01-18 |
| IL42223A0 (en) | 1973-07-30 |
| CS174195B2 (hu) | 1977-03-31 |
| CH599149A5 (hu) | 1978-05-12 |
| AU5361873A (en) | 1974-09-26 |
| NL7305222A (hu) | 1973-10-16 |
| GB1425962A (en) | 1976-02-25 |
| DK147468B (da) | 1984-08-20 |
| US4035392A (en) | 1977-07-12 |
| DE2318785A1 (de) | 1973-10-25 |
| NO143575C (no) | 1981-03-11 |
| GB1425961A (en) | 1976-02-25 |
| HK3277A (en) | 1977-01-28 |
| DE2318785C2 (de) | 1983-01-27 |
| NL182400B (nl) | 1987-10-01 |
| ATA315173A (de) | 1978-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |