JPS577148B2 - - Google Patents

Info

Publication number
JPS577148B2
JPS577148B2 JP4204973A JP4204973A JPS577148B2 JP S577148 B2 JPS577148 B2 JP S577148B2 JP 4204973 A JP4204973 A JP 4204973A JP 4204973 A JP4204973 A JP 4204973A JP S577148 B2 JPS577148 B2 JP S577148B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP4204973A
Other versions
JPS4913145A (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4913145A publication Critical patent/JPS4913145A/ja
Publication of JPS577148B2 publication Critical patent/JPS577148B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP4204973A 1972-04-13 1973-04-13 Expired JPS577148B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2306372 1972-04-13
IT2366272 1972-04-28

Publications (2)

Publication Number Publication Date
JPS4913145A JPS4913145A (ja) 1974-02-05
JPS577148B2 true JPS577148B2 (ja) 1982-02-09

Family

ID=26328323

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4204973A Expired JPS577148B2 (ja) 1972-04-13 1973-04-13

Country Status (18)

Country Link
US (4) US3935254A (ja)
JP (1) JPS577148B2 (ja)
AT (1) AT351177B (ja)
CA (1) CA1016166A (ja)
CH (2) CH599149A5 (ja)
CS (1) CS174195B2 (ja)
DE (1) DE2318785C2 (ja)
DK (1) DK147468C (ja)
FR (2) FR2187334B1 (ja)
GB (2) GB1425962A (ja)
HK (1) HK3277A (ja)
HU (1) HU169182B (ja)
IL (1) IL42223A (ja)
MY (1) MY7700132A (ja)
NL (1) NL182400C (ja)
NO (1) NO143575C (ja)
SE (1) SE406762B (ja)
SU (1) SU656510A3 (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO150117C (no) * 1974-09-17 1984-08-22 Erba Farmitalia Analogifremgangsmaate for fremstilling av terapeutisk aktive prostaglandinderivater
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
DK155317C (da) * 1974-09-25 1989-08-14 Erba Carlo Spa 13,14-dehydro-prostaglandin-f2alfa-derivater til anvendelse i midler med abortfremkaldende aktivitet
US4169145A (en) * 1974-09-25 1979-09-25 Carlo Erba S.P.A. ω-Nor-cycloalkyl-13,14-dehydro-prostaglandins
AU501803B2 (en) * 1975-03-21 1979-06-28 Farmitalia Carlo Erba S.P.A. Fluoro-prostaglandins
US4029681A (en) * 1976-02-13 1977-06-14 The Upjohn Company 13,14-Didehydro-PG analogs
US4140721A (en) * 1976-07-26 1979-02-20 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-13,14-didehydro-17-phenyl-PGA, PGD and PGE compounds
US4058564A (en) * 1976-07-26 1977-11-15 The Upjohn Company Aliphatic 2-decarboxy-2-hydroxymethyl-13,14-didehydro-PG compounds
US4207422A (en) * 1976-07-26 1980-06-10 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-13,14-didehydro-PGA, PGD, and PGE compounds
DE2655004C3 (de) * 1976-12-02 1980-06-19 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von bicyclischen Laktonen
JPS5662969A (en) * 1979-10-26 1981-05-29 Mitsubishi Gas Chem Co Inc Preventing method for corrosion of metal surface
US4310700A (en) 1980-04-03 1982-01-12 American Cyanamid Company 1-Hydroxylmethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives
US4291175A (en) * 1980-04-03 1981-09-22 American Cyanamid Company 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives
US4291174A (en) * 1980-04-03 1981-09-22 American Cyanamid Company 1-Hydroxymethyl-15-hydroxy-prosten-1-ol derivatives
US4288629A (en) 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives
US4288633A (en) 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives
US4288630A (en) 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11,15-dihydroxy-prosten-1-ol-derivatives
US4288632A (en) 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11,16-dihydroxy-prosten-1-ol derivatives
US4543353A (en) * 1981-11-27 1985-09-24 Farmitalia Carlo Erba S.P.A. Ester and amide derivatives of 13,14-didehydro prostaglandins
CZ2015376A3 (cs) * 2015-06-03 2016-12-21 Univerzita Pardubice Způsob přípravy intermediátu přípravy prostaglandinového derivátu alfaprostolu
CN110256385A (zh) * 2019-07-10 2019-09-20 上海玉函化工有限公司 一种前列腺素类药物中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728382A (en) * 1970-05-04 1973-04-17 Upjohn Co 15-methyl and 15-ethyl prostaglandin analogs
US3711515A (en) * 1970-11-27 1973-01-16 Upjohn Co Tricyclic lactone alkene or alkenyne

Also Published As

Publication number Publication date
DE2318785A1 (de) 1973-10-25
FR2187334B1 (ja) 1979-02-23
ATA315173A (de) 1978-12-15
HU169182B (ja) 1976-10-28
SE406762B (sv) 1979-02-26
AU5361873A (en) 1974-09-26
US4021477A (en) 1977-05-03
DK147468B (da) 1984-08-20
FR2187334A1 (ja) 1974-01-18
FR2279744A1 (fr) 1976-02-20
JPS4913145A (ja) 1974-02-05
HK3277A (en) 1977-01-28
CH591441A5 (ja) 1977-09-15
AT351177B (de) 1979-07-10
NL182400C (nl) 1988-03-01
FR2279744B1 (ja) 1979-02-02
NL7305222A (ja) 1973-10-16
US4035392A (en) 1977-07-12
DE2318785C2 (de) 1983-01-27
US3935254A (en) 1976-01-27
SU656510A3 (ru) 1979-04-05
DK147468C (da) 1985-02-04
CS174195B2 (ja) 1977-03-31
IL42223A (en) 1977-01-31
US4035414A (en) 1977-07-12
GB1425961A (en) 1976-02-25
NL182400B (nl) 1987-10-01
CA1016166A (en) 1977-08-23
NO143575C (no) 1981-03-11
IL42223A0 (en) 1973-07-30
CH599149A5 (ja) 1978-05-12
GB1425962A (en) 1976-02-25
NO143575B (no) 1980-12-01
MY7700132A (en) 1977-12-31

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