CA1016166A - Prostanoic acid derivatives and process for their preparation - Google Patents
Prostanoic acid derivatives and process for their preparationInfo
- Publication number
- CA1016166A CA1016166A CA168,551A CA168551A CA1016166A CA 1016166 A CA1016166 A CA 1016166A CA 168551 A CA168551 A CA 168551A CA 1016166 A CA1016166 A CA 1016166A
- Authority
- CA
- Canada
- Prior art keywords
- preparation
- acid derivatives
- prostanoic acid
- prostanoic
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WGJJROVFWIXTPA-OALUTQOASA-N prostanoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC(O)=O WGJJROVFWIXTPA-OALUTQOASA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2306372 | 1972-04-13 | ||
IT2366272 | 1972-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1016166A true CA1016166A (en) | 1977-08-23 |
Family
ID=26328323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA168,551A Expired CA1016166A (en) | 1972-04-13 | 1973-04-12 | Prostanoic acid derivatives and process for their preparation |
Country Status (18)
Country | Link |
---|---|
US (4) | US3935254A (hu) |
JP (1) | JPS577148B2 (hu) |
AT (1) | AT351177B (hu) |
CA (1) | CA1016166A (hu) |
CH (2) | CH599149A5 (hu) |
CS (1) | CS174195B2 (hu) |
DE (1) | DE2318785C2 (hu) |
DK (1) | DK147468C (hu) |
FR (2) | FR2187334B1 (hu) |
GB (2) | GB1425961A (hu) |
HK (1) | HK3277A (hu) |
HU (1) | HU169182B (hu) |
IL (1) | IL42223A (hu) |
MY (1) | MY7700132A (hu) |
NL (1) | NL182400C (hu) |
NO (1) | NO143575C (hu) |
SE (1) | SE406762B (hu) |
SU (1) | SU656510A3 (hu) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4041064A (en) * | 1974-09-17 | 1977-08-09 | Carlo-Erba S.P.A. | 16-Methyl prost-5-en-13-ynoic acid derivatives |
IT1053781B (it) * | 1974-09-25 | 1981-10-10 | Erba C S P A Ora Farmitalia | Omega nor cicloalcil 13.14 deidro prostaglandine |
DK155317C (da) * | 1974-09-25 | 1989-08-14 | Erba Carlo Spa | 13,14-dehydro-prostaglandin-f2alfa-derivater til anvendelse i midler med abortfremkaldende aktivitet |
US4169145A (en) * | 1974-09-25 | 1979-09-25 | Carlo Erba S.P.A. | ω-Nor-cycloalkyl-13,14-dehydro-prostaglandins |
AU501803B2 (en) * | 1975-03-21 | 1979-06-28 | Farmitalia Carlo Erba S.P.A. | Fluoro-prostaglandins |
US4029681A (en) * | 1976-02-13 | 1977-06-14 | The Upjohn Company | 13,14-Didehydro-PG analogs |
US4140721A (en) * | 1976-07-26 | 1979-02-20 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-13,14-didehydro-17-phenyl-PGA, PGD and PGE compounds |
US4058564A (en) * | 1976-07-26 | 1977-11-15 | The Upjohn Company | Aliphatic 2-decarboxy-2-hydroxymethyl-13,14-didehydro-PG compounds |
US4207422A (en) * | 1976-07-26 | 1980-06-10 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-13,14-didehydro-PGA, PGD, and PGE compounds |
DE2655004C3 (de) * | 1976-12-02 | 1980-06-19 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von bicyclischen Laktonen |
JPS5662969A (en) * | 1979-10-26 | 1981-05-29 | Mitsubishi Gas Chem Co Inc | Preventing method for corrosion of metal surface |
US4288632A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11,16-dihydroxy-prosten-1-ol derivatives |
US4291175A (en) * | 1980-04-03 | 1981-09-22 | American Cyanamid Company | 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives |
US4288630A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11,15-dihydroxy-prosten-1-ol-derivatives |
US4310700A (en) | 1980-04-03 | 1982-01-12 | American Cyanamid Company | 1-Hydroxylmethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives |
US4288629A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives |
US4288633A (en) | 1980-04-03 | 1981-09-08 | American Cyanamid Company | 1-Hydroxymethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives |
US4291174A (en) * | 1980-04-03 | 1981-09-22 | American Cyanamid Company | 1-Hydroxymethyl-15-hydroxy-prosten-1-ol derivatives |
CH656877A5 (de) * | 1981-11-27 | 1986-07-31 | Erba Farmitalia | Optisch aktive oder racemische prostaglandinderivate. |
CZ306366B6 (cs) * | 2015-06-03 | 2016-12-21 | Univerzita Pardubice | Způsob přípravy intermediátu přípravy prostaglandinového derivátu alfaprostolu |
CN110256385A (zh) * | 2019-07-10 | 2019-09-20 | 上海玉函化工有限公司 | 一种前列腺素类药物中间体的制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3728382A (en) * | 1970-05-04 | 1973-04-17 | Upjohn Co | 15-methyl and 15-ethyl prostaglandin analogs |
US3711515A (en) * | 1970-11-27 | 1973-01-16 | Upjohn Co | Tricyclic lactone alkene or alkenyne |
-
1973
- 1973-03-23 GB GB1422273A patent/GB1425961A/en not_active Expired
- 1973-03-23 GB GB2731375A patent/GB1425962A/en not_active Expired
- 1973-03-30 US US05/346,249 patent/US3935254A/en not_active Expired - Lifetime
- 1973-04-10 AT AT315173A patent/AT351177B/de not_active IP Right Cessation
- 1973-04-10 DK DK193573A patent/DK147468C/da not_active IP Right Cessation
- 1973-04-12 SU SU731919945A patent/SU656510A3/ru active
- 1973-04-12 CA CA168,551A patent/CA1016166A/en not_active Expired
- 1973-04-12 SE SE7305181A patent/SE406762B/xx unknown
- 1973-04-12 CS CS2593A patent/CS174195B2/cs unknown
- 1973-04-12 NO NO1537/73A patent/NO143575C/no unknown
- 1973-04-13 DE DE2318785A patent/DE2318785C2/de not_active Expired
- 1973-04-13 JP JP4204973A patent/JPS577148B2/ja not_active Expired
- 1973-04-13 CH CH424376A patent/CH599149A5/xx not_active IP Right Cessation
- 1973-04-13 HU HUEA128A patent/HU169182B/hu unknown
- 1973-04-13 FR FR7313538A patent/FR2187334B1/fr not_active Expired
- 1973-04-13 NL NLAANVRAGE7305222,A patent/NL182400C/xx not_active IP Right Cessation
- 1973-04-13 CH CH538273A patent/CH591441A5/xx not_active IP Right Cessation
- 1973-05-08 IL IL42223A patent/IL42223A/en unknown
-
1975
- 1975-02-05 US US05/547,247 patent/US4035392A/en not_active Expired - Lifetime
- 1975-08-26 FR FR7526314A patent/FR2279744A1/fr active Granted
- 1975-11-13 US US05/631,655 patent/US4021477A/en not_active Expired - Lifetime
- 1975-11-13 US US05/631,656 patent/US4035414A/en not_active Expired - Lifetime
-
1977
- 1977-01-20 HK HK32/77A patent/HK3277A/xx unknown
- 1977-12-30 MY MY132/77A patent/MY7700132A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US4021477A (en) | 1977-05-03 |
CH591441A5 (hu) | 1977-09-15 |
GB1425961A (en) | 1976-02-25 |
DK147468B (da) | 1984-08-20 |
AT351177B (de) | 1979-07-10 |
US4035392A (en) | 1977-07-12 |
FR2187334A1 (hu) | 1974-01-18 |
NO143575B (no) | 1980-12-01 |
NL182400C (nl) | 1988-03-01 |
SE406762B (sv) | 1979-02-26 |
JPS577148B2 (hu) | 1982-02-09 |
AU5361873A (en) | 1974-09-26 |
HU169182B (hu) | 1976-10-28 |
FR2187334B1 (hu) | 1979-02-23 |
CH599149A5 (hu) | 1978-05-12 |
NL7305222A (hu) | 1973-10-16 |
US3935254A (en) | 1976-01-27 |
HK3277A (en) | 1977-01-28 |
MY7700132A (en) | 1977-12-31 |
GB1425962A (en) | 1976-02-25 |
JPS4913145A (hu) | 1974-02-05 |
IL42223A (en) | 1977-01-31 |
NL182400B (nl) | 1987-10-01 |
ATA315173A (de) | 1978-12-15 |
FR2279744B1 (hu) | 1979-02-02 |
DE2318785A1 (de) | 1973-10-25 |
DE2318785C2 (de) | 1983-01-27 |
IL42223A0 (en) | 1973-07-30 |
CS174195B2 (hu) | 1977-03-31 |
FR2279744A1 (fr) | 1976-02-20 |
US4035414A (en) | 1977-07-12 |
SU656510A3 (ru) | 1979-04-05 |
NO143575C (no) | 1981-03-11 |
DK147468C (da) | 1985-02-04 |
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