DK1470818T3 - Anvendelse af Piperazin-phenothiazin-derivater til fremstilling af et medikament med neurobeskyttende og/eller neurotrofiske effekter på CNS og/eller PNS - Google Patents
Anvendelse af Piperazin-phenothiazin-derivater til fremstilling af et medikament med neurobeskyttende og/eller neurotrofiske effekter på CNS og/eller PNSInfo
- Publication number
- DK1470818T3 DK1470818T3 DK03291024T DK03291024T DK1470818T3 DK 1470818 T3 DK1470818 T3 DK 1470818T3 DK 03291024 T DK03291024 T DK 03291024T DK 03291024 T DK03291024 T DK 03291024T DK 1470818 T3 DK1470818 T3 DK 1470818T3
- Authority
- DK
- Denmark
- Prior art keywords
- hours
- neuroprotective
- pns
- cns
- phenothiazine derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03291024A EP1470818B1 (en) | 2003-04-25 | 2003-04-25 | Use of piperazine phenothiazine derivatives in the manufacture of a medicament with neuroprotector and/or neurotrophic effects on cns and/or pns |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1470818T3 true DK1470818T3 (da) | 2006-11-20 |
Family
ID=32946961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03291024T DK1470818T3 (da) | 2003-04-25 | 2003-04-25 | Anvendelse af Piperazin-phenothiazin-derivater til fremstilling af et medikament med neurobeskyttende og/eller neurotrofiske effekter på CNS og/eller PNS |
Country Status (9)
Country | Link |
---|---|
US (1) | US20060276460A1 (da) |
EP (1) | EP1470818B1 (da) |
AT (1) | ATE333881T1 (da) |
DE (1) | DE60307049T2 (da) |
DK (1) | DK1470818T3 (da) |
ES (1) | ES2272911T3 (da) |
HK (1) | HK1066741A1 (da) |
PT (1) | PT1470818E (da) |
WO (1) | WO2004096231A2 (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2911143A1 (fr) * | 2007-01-05 | 2008-07-11 | Servier Lab | Utilisation de composes neuroprotecteurs pour l'obtention de medicaments destines au traitement de maladies neurodegeneratives. |
GB0701970D0 (en) * | 2007-02-01 | 2007-03-14 | Wilson Stuart | Treatment of protein aggregation diseases |
DE102010062810B4 (de) * | 2010-09-07 | 2014-03-13 | Immungenetics Ag | 2-(R2-Thio)-10-[3-(4-R1-piperazin-1-yl)propyl]-10H-phenothiazine zur Behandlung neurodegenerativer Erkrankungen ausgewählt aus beta-Amyloidopathien und alpha-Synucleinopathien |
WO2013043744A2 (en) * | 2011-09-21 | 2013-03-28 | Inception 1, Inc. | Tricyclic compounds useful as neurogenic and neuroprotective agents |
JP2017507977A (ja) * | 2014-03-10 | 2017-03-23 | ユニヴェルシテ デクス−マルセイユUniversite D’Aix−Marseille | 痙縮を治療するためのピペラジンフェノチアジン誘導体 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3058979A (en) * | 1957-05-13 | 1962-10-16 | Smith Kline French Lab | New perfluoroalkylphenothiazine derivatives |
US3194733A (en) * | 1961-04-26 | 1965-07-13 | Olin Mathicson Chemical Corp | Phenothiazine compositions and method of treating mental disorders |
US3320245A (en) * | 1964-08-21 | 1967-05-16 | American Home Prod | Derivatives of phenothiazine-10-glyoxylic acids and intermediates in the preparationthereof |
US3320249A (en) * | 1965-07-09 | 1967-05-16 | Olin Mathieson | Adamantyl derivatives of phenothiazines |
CA2115792C (en) * | 1993-03-05 | 2005-11-01 | David J. Mayer | Method for the treatment of pain |
AU708682B2 (en) * | 1994-08-08 | 1999-08-12 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for treating and/or preventing Alzheimer's disease using phenothiazines and/or thioxanthenes |
US6514686B2 (en) * | 1997-04-28 | 2003-02-04 | The University Of British Columbia | Method and composition for modulating amyloidosis |
US6057373A (en) * | 1997-05-22 | 2000-05-02 | Synchroneuron, Llc | Methods of treating tardive dyskinesia and other movement disorders using NMDA receptor antagonists |
WO1999007356A1 (en) * | 1997-08-11 | 1999-02-18 | University Of South Florida Research Foundation, Inc. | Nicotine antagonists for neuropsychiatric disorders |
FR2784678B1 (fr) * | 1998-09-23 | 2002-11-29 | Sod Conseils Rech Applic | Nouveaux derives de n-(iminomethyl)amines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
EE200100302A (et) * | 1998-12-02 | 2002-08-15 | Pfizer Products Inc. | Meetodid ja kompositsioonid p53 perekonna valgu konformatsioonilise stabiilsuse taastamiseks |
AU2001253597A1 (en) * | 2000-04-12 | 2001-10-30 | Minerva Biotechnologies Corporation | Treatment of neurodegenerative disease |
CA2310205A1 (en) * | 2000-05-29 | 2001-11-29 | Dalhousie University | Unknown |
CA2418720A1 (en) * | 2000-09-13 | 2002-03-21 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
TWI248438B (en) * | 2001-04-10 | 2006-02-01 | Sod Conseils Rech Applic | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments |
US20030229082A1 (en) * | 2002-01-16 | 2003-12-11 | The Regents Of The University Of California | Inhibition of RNA function |
FR2835254B1 (fr) * | 2002-01-25 | 2006-04-07 | Sod Conseils Rech Applic | Derives de thiazoles dans le traitement de maladies neurologiques |
-
2003
- 2003-04-25 EP EP03291024A patent/EP1470818B1/en not_active Expired - Lifetime
- 2003-04-25 PT PT03291024T patent/PT1470818E/pt unknown
- 2003-04-25 DK DK03291024T patent/DK1470818T3/da active
- 2003-04-25 DE DE60307049T patent/DE60307049T2/de not_active Expired - Lifetime
- 2003-04-25 ES ES03291024T patent/ES2272911T3/es not_active Expired - Lifetime
- 2003-04-25 AT AT03291024T patent/ATE333881T1/de not_active IP Right Cessation
-
2004
- 2004-04-23 US US10/551,395 patent/US20060276460A1/en not_active Abandoned
- 2004-04-23 WO PCT/EP2004/005183 patent/WO2004096231A2/en active Application Filing
- 2004-12-14 HK HK04109910A patent/HK1066741A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1470818B1 (en) | 2006-07-26 |
ES2272911T3 (es) | 2007-05-01 |
US20060276460A1 (en) | 2006-12-07 |
PT1470818E (pt) | 2006-11-30 |
WO2004096231A3 (en) | 2005-03-24 |
EP1470818A1 (en) | 2004-10-27 |
DE60307049D1 (de) | 2006-09-07 |
HK1066741A1 (en) | 2005-04-01 |
WO2004096231A2 (en) | 2004-11-11 |
DE60307049T2 (de) | 2007-02-08 |
ATE333881T1 (de) | 2006-08-15 |
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