ATE420101T1 - Isolierung von nervenstammzellen unter verwendung von gangliosiden und anderen oberflächenmarkern - Google Patents

Isolierung von nervenstammzellen unter verwendung von gangliosiden und anderen oberflächenmarkern

Info

Publication number
ATE420101T1
ATE420101T1 AT02731460T AT02731460T ATE420101T1 AT E420101 T1 ATE420101 T1 AT E420101T1 AT 02731460 T AT02731460 T AT 02731460T AT 02731460 T AT02731460 T AT 02731460T AT E420101 T1 ATE420101 T1 AT E420101T1
Authority
AT
Austria
Prior art keywords
molecules
stem cells
identified
neural
markers
Prior art date
Application number
AT02731460T
Other languages
English (en)
Inventor
Henry Klassen
Michael Schwartz
Michael Young
Original Assignee
Children S Hospital Of Orange
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Children S Hospital Of Orange filed Critical Children S Hospital Of Orange
Application granted granted Critical
Publication of ATE420101T1 publication Critical patent/ATE420101T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02731460T 2001-04-20 2002-04-22 Isolierung von nervenstammzellen unter verwendung von gangliosiden und anderen oberflächenmarkern ATE420101T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28540701P 2001-04-20 2001-04-20

Publications (1)

Publication Number Publication Date
ATE420101T1 true ATE420101T1 (de) 2009-01-15

Family

ID=23094102

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02731460T ATE420101T1 (de) 2001-04-20 2002-04-22 Isolierung von nervenstammzellen unter verwendung von gangliosiden und anderen oberflächenmarkern

Country Status (7)

Country Link
US (2) US7419825B2 (de)
EP (1) EP1425297B1 (de)
AT (1) ATE420101T1 (de)
AU (1) AU2002303437A1 (de)
CA (1) CA2444706C (de)
DE (1) DE60230774D1 (de)
WO (1) WO2002086082A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040214766A1 (en) * 2001-10-01 2004-10-28 Kari Alitalo VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
US20030186335A1 (en) * 2002-03-28 2003-10-02 National Institute Of Advanced Industrial Science And Technology Monoclonal antibodies, hybridomas, cell isolation method, isolated cells and immunological diagnostic method
JP2006511206A (ja) 2002-08-27 2006-04-06 ステムセルズ， インコーポレイテッド 富化された中枢神経系幹細胞集団および前駆体細胞集団、ならびにこれらの集団を同定し、単離し、そして富化する方法
US8642332B2 (en) * 2003-03-07 2014-02-04 Cornell Research Foundation, Inc. Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain
US20040203142A1 (en) * 2003-04-14 2004-10-14 Reliance Life Sciences Pvt. Ltd. Growth of neural precursor cells using umbilical cord blood serum and a process for the preparation thereof for therapeutic purposes
JP5099288B2 (ja) * 2003-09-09 2012-12-19 学校法人慶應義塾 神経幹細胞の生存及び／又は増殖及び神経突起伸張を促進する方法並びに促進剤、神経幹細胞を含む医薬組成物、検定方法、スクリーニング方法
US7259011B2 (en) * 2004-05-20 2007-08-21 Paul Lucas Pluripotent adult stem cells
WO2008097828A2 (en) * 2007-02-02 2008-08-14 St. Jude Children's Research Hospital Method for isolating mesenchymal stromal cells
EP2022848A1 (de) 2007-08-10 2009-02-11 Hubrecht Institut Verfahren zur Identifikation, Vermehrung und Entfernung erwachsener Stammzellen und Krebsstammzellen
KR101972610B1 (ko) 2011-05-18 2019-04-25 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 망막 질환을 치료하기 위한 조성물 및 방법
WO2013130603A1 (en) * 2012-02-27 2013-09-06 Board Of Regents, The University Of Texas System Ganglioside gd2 as a marker and target on cancer stem cells
WO2014113704A2 (en) * 2013-01-18 2014-07-24 Escape Therapeutics, Inc. Enhanced differentiation of mesenchymal stem cells
JP2016533770A (ja) * 2014-09-05 2016-11-04 コリア リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジーＫｏｒｅａ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｂｉｏｓｃｉｅｎｃｅ Ａｎｄ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｇｍ１ガングリオシドーシスのヒト細胞モデルおよびその使用
JP2019508502A (ja) * 2016-03-09 2019-03-28 エーエーエル サイエンティフィックス，インコーポレイテッド 神経幹細胞およびその使用
JP2018011527A (ja) * 2016-07-19 2018-01-25 学校法人藤田学園 視床下部前駆細胞の精製方法及びその利用
US20190369093A1 (en) * 2016-08-17 2019-12-05 Xintela Ab Marker for Neural Stem Cells
GB201615714D0 (en) 2016-09-15 2016-11-02 Univ Of Sheffield The Otic progenitor identification and isolation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646001A (en) * 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
EP0658194A1 (de) 1992-07-27 1995-06-21 California Institute Of Technology Multipotenten neuronalen säugetierstammzellen
US5693482A (en) 1992-07-27 1997-12-02 California Institute Of Technology Neural chest stem cell assay
US5466572A (en) * 1992-09-03 1995-11-14 Systemix, Inc. High speed flow cytometric separation of viable cells
DE69434974T2 (de) * 1993-03-29 2008-02-07 Kyowa Hakko Kogyo K.K. alpha-2,8 SIALYLTRANSFERASE
US5550019A (en) * 1993-05-26 1996-08-27 La Jolla Cancer Research Foundation Methods of identifying compounds which alter apoptosis
US5843633A (en) * 1996-04-26 1998-12-01 Amcell Corporation Characterization of a human hematopoietic progenitor cell antigen
US6235527B1 (en) * 1997-11-29 2001-05-22 University Of Utah Research Foundation Lineage restricted glial precursors from the central nervous system
CA2311729A1 (en) * 1998-01-23 1999-07-29 Imclone Systems Incorporated Purified populations of stem cells
US6468794B1 (en) * 1999-02-12 2002-10-22 Stemcells, Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
JP2006511206A (ja) 2002-08-27 2006-04-06 ステムセルズ， インコーポレイテッド 富化された中枢神経系幹細胞集団および前駆体細胞集団、ならびにこれらの集団を同定し、単離し、そして富化する方法

Also Published As

Publication number Publication date
CA2444706C (en) 2015-06-30
CA2444706A1 (en) 2002-10-31
US7419825B2 (en) 2008-09-02
EP1425297A2 (de) 2004-06-09
US20080213893A1 (en) 2008-09-04
US20030040023A1 (en) 2003-02-27
DE60230774D1 (de) 2009-02-26
AU2002303437A1 (en) 2002-11-05
EP1425297B1 (de) 2009-01-07
EP1425297A4 (de) 2005-10-19
WO2002086082A3 (en) 2004-04-08
US8241897B2 (en) 2012-08-14
WO2002086082A2 (en) 2002-10-31

Similar Documents

Publication Publication Date Title
ATE420101T1 (de) Isolierung von nervenstammzellen unter verwendung von gangliosiden und anderen oberflächenmarkern
Haas et al. Adult stem cell therapy in stroke
Bernal et al. Neural stem cells as therapeutic agents for age‐related brain repair
NO20051030L (no) Funksjonelle kardiomyocytter fra humane embryonale stamceller
CA2338541A1 (en) Genetically modified cd34-negative adherently growing stem cells and their use in gene therapy
WO2005046570A3 (en) Human stem cell materials and methods
WO2007051038A3 (en) Pdx1-expressing dorsal and ventral foregut endoderm
SG152273A1 (en) Pdx1 expressing endoderm
WO2002092756A8 (en) Insulin producing cells derived from human embryonic stem cells
MX2009006685A (es) Antagonistas del dr6 y usos de los mismos en el tratamiento de trastornos neurologicos.
Kunkel et al. Cell line-directed screening assay for inhibitors of thioredoxin reductase signaling as potential anti-cancer drugs
DE69837491D1 (de) Menschliche mesenchymale stammzellen aus peripherem blut
WO2003016507A3 (en) Generation of multipotent central nervous system stem cells
WO2006060709A3 (en) Biological pathways in progenitor cells
BRPI0412715A (pt) células precursoras de oligodendrócitos e métodos de obter e cultivar as mesmas
WO2000066730A3 (en) Laminin 2 and methods for its use
WO2006044842A3 (en) Pancreatic islet beta-cell-like macrophages and methods to produce them
NO971341D0 (no) Promoter for reseptor tyrosinkinase TIE
YU217890A (sh) Postupak za dobijanje genetskih konstrukcija za ekspresiju nervnog faktora rasta u eukariotskim ćelijama
WO1997026322A3 (en) Methods and compositions for inhibiting hexokinase
DE60044655D1 (de) Angereicherte Zellpopulationen des zentralen Nervensystems
WO2004043990A3 (en) Human stem cell materials and methods
BR9906926A (pt) Composições e métodos para tratamento de células tendo dna de minuto duplo
EP2377922A3 (de) PDX1-exprimierendes Endoderm
WO2001042784A3 (en) Methods for screening compounds active on neurons

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties