DK144176B - Analogifremgangsmaade til fremstilling af 3-(1-piperazinyl)-pyrido (2,3-b)-pyraziner eller farmaceutisk acceptable salte heraf - Google Patents

Analogifremgangsmaade til fremstilling af 3-(1-piperazinyl)-pyrido (2,3-b)-pyraziner eller farmaceutisk acceptable salte heraf Download PDF

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Publication number
DK144176B
DK144176B DK97778AA DK97778A DK144176B DK 144176 B DK144176 B DK 144176B DK 97778A A DK97778A A DK 97778AA DK 97778 A DK97778 A DK 97778A DK 144176 B DK144176 B DK 144176B
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DK
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Prior art keywords
piperazinyl
pyrido
preparation
acceptable salts
pyrazines
Prior art date
Application number
DK97778AA
Other languages
Danish (da)
English (en)
Other versions
DK97778A (da
Inventor
W S Saari
W C Lumma
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK97778A publication Critical patent/DK97778A/da
Publication of DK144176B publication Critical patent/DK144176B/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK97778AA 1977-04-25 1978-03-03 Analogifremgangsmaade til fremstilling af 3-(1-piperazinyl)-pyrido (2,3-b)-pyraziner eller farmaceutisk acceptable salte heraf DK144176B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79036277 1977-04-25
US05/790,362 US4082845A (en) 1977-04-25 1977-04-25 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines

Publications (2)

Publication Number Publication Date
DK97778A DK97778A (da) 1978-10-26
DK144176B true DK144176B (da) 1982-01-04

Family

ID=25150460

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97778AA DK144176B (da) 1977-04-25 1978-03-03 Analogifremgangsmaade til fremstilling af 3-(1-piperazinyl)-pyrido (2,3-b)-pyraziner eller farmaceutisk acceptable salte heraf

Country Status (10)

Country Link
US (1) US4082845A (fr)
JP (1) JPS53132595A (fr)
CH (1) CH639661A5 (fr)
DE (1) DE2810036A1 (fr)
DK (1) DK144176B (fr)
FR (1) FR2388811A1 (fr)
GB (1) GB1570567A (fr)
IT (1) IT7848655A0 (fr)
NL (1) NL7802829A (fr)
SE (1) SE7802568L (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242344A (en) * 1979-01-22 1980-12-30 Merck & Co., Inc. Piperazinyl-imidazo[1,2-a]pyrazines
FR2527608B1 (fr) * 1982-05-28 1986-10-10 Sandoz Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments
US8217042B2 (en) 2005-11-11 2012-07-10 Zentaris Gmbh Pyridopyrazines and their use as modulators of kinases
EP1790342A1 (fr) * 2005-11-11 2007-05-30 Zentaris GmbH Dérivés de pyridopyrazine et leur utilisation comme modulateurs de transduction de signal
NZ586418A (en) 2007-12-19 2012-09-28 Cancer Rec Tech Ltd Pyrido[2,3-b]pyrazine-8-substituted compounds and their use
WO2011092469A1 (fr) 2010-02-01 2011-08-04 Cancer Research Technology Limited 1-(5-tert-butyl-2-phényl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-méthyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phényl]-urée et composés associés, et leur utilisation dans des traitements
GB201320732D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Methods of chemical synthesis
GB201320729D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Therapeutic compounds and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI193974A (fr) 1973-07-13 1975-01-14 Merck & Co Inc

Also Published As

Publication number Publication date
FR2388811A1 (fr) 1978-11-24
US4082845A (en) 1978-04-04
CH639661A5 (de) 1983-11-30
SE7802568L (sv) 1978-10-26
DE2810036A1 (de) 1978-11-02
JPS53132595A (en) 1978-11-18
FR2388811B1 (fr) 1982-06-11
DK97778A (da) 1978-10-26
GB1570567A (en) 1980-07-02
NL7802829A (nl) 1978-10-27
IT7848655A0 (it) 1978-03-29

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