DK1438065T3 - Anvendelse af kollagenase til at lette passage af en ledetråd gennem kroniske arterieokklusioner - Google Patents

Anvendelse af kollagenase til at lette passage af en ledetråd gennem kroniske arterieokklusioner

Info

Publication number
DK1438065T3
DK1438065T3 DK02764443.4T DK02764443T DK1438065T3 DK 1438065 T3 DK1438065 T3 DK 1438065T3 DK 02764443 T DK02764443 T DK 02764443T DK 1438065 T3 DK1438065 T3 DK 1438065T3
Authority
DK
Denmark
Prior art keywords
clue
collagenase
facilitate passage
artery occlusions
chronic artery
Prior art date
Application number
DK02764443.4T
Other languages
English (en)
Inventor
H Strauss Bradley
Original Assignee
Matrizyme Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matrizyme Pharma Corp filed Critical Matrizyme Pharma Corp
Application granted granted Critical
Publication of DK1438065T3 publication Critical patent/DK1438065T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24003—Microbial collagenase (3.4.24.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK02764443.4T 2001-10-01 2002-10-01 Anvendelse af kollagenase til at lette passage af en ledetråd gennem kroniske arterieokklusioner DK1438065T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32553901P 2001-10-01 2001-10-01
PCT/CA2002/001476 WO2003028756A2 (en) 2001-10-01 2002-10-01 An in vivo animal model of chronic arterial occlusion and use of collagenase to facilitate guide wire crossing in chronic arterial occlusions

Publications (1)

Publication Number Publication Date
DK1438065T3 true DK1438065T3 (da) 2013-02-11

Family

ID=23268311

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02764443.4T DK1438065T3 (da) 2001-10-01 2002-10-01 Anvendelse af kollagenase til at lette passage af en ledetråd gennem kroniske arterieokklusioner

Country Status (13)

Country Link
US (3) US20050053548A1 (da)
EP (1) EP1438065B1 (da)
JP (1) JP2005503820A (da)
CN (1) CN1327893C (da)
AU (1) AU2002328729C1 (da)
CA (1) CA2462512C (da)
DK (1) DK1438065T3 (da)
ES (1) ES2396964T3 (da)
HK (1) HK1076037A1 (da)
IL (2) IL161137A0 (da)
PT (1) PT1438065E (da)
SI (1) SI1438065T1 (da)
WO (1) WO2003028756A2 (da)

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CA2401660A1 (en) * 2000-03-02 2001-09-07 Incyte Genomics, Inc. Lipid metabolism enzymes
US6569129B1 (en) * 2000-09-13 2003-05-27 Mayo Foundation For Medical Education And Research Biological revascularization
CN1327893C (zh) * 2001-10-01 2007-07-25 布雷德利 胶原酶在促进导线在完全动脉闭塞内通过中的应用
WO2005097177A1 (en) * 2004-04-08 2005-10-20 Strauss Bradley H Use of collagenase to facilitate guide wire crossing in total arterial occlusions
CA2589523C (en) * 2004-12-02 2016-01-05 Bradley H. Strauss Augmentation of intraluminal microvessel formation to facilitate guide wire crossing in chronic total occlusions
JP2007181413A (ja) * 2006-01-05 2007-07-19 Fujifilm Corp 血管壁障害モデル動物の作成方法
US20070184083A1 (en) * 2006-02-07 2007-08-09 Medtronic Vascular, Inc. Drug-Eluting Device for Treatment of Chronic Total Occlusions
ES2335167B1 (es) * 2007-02-26 2011-01-24 Proyecto De Biomedicina Cima, S.L. Uso de la metaloproteinasa de matriz-10 (mmp10) para tratamientos tromboliticos.
US8541370B2 (en) 2007-02-26 2013-09-24 Proyecto De Biomedicina Cima, S.L. Use of matrix metalloproteinase-10 (MMP-10) for thrombolytic treatments
US10071143B1 (en) 2007-05-03 2018-09-11 The Research Foundation For The State University Of New York Methods for non-surgical treatment of carpal tunnel syndrome
US8016799B2 (en) * 2008-04-22 2011-09-13 Medtronic Vascular, Inc. Catheter having a detachable tip
WO2011130537A2 (en) 2010-04-14 2011-10-20 Northwestern University Pharmaceutical compositions and methods for digesting atherosclerotic plaques
US20120259314A1 (en) * 2011-04-11 2012-10-11 Medtronic Vascular, Inc. Apparatus and Methods for Recanalization of a Chronic Total Occlusion
CN103157099B (zh) * 2011-12-19 2015-03-18 吴宗贵 一种用于血管外膜快速消化的混合酶消液及其制备方法
WO2014066622A2 (en) 2012-10-24 2014-05-01 The Research Foundation For The State University Of New York Use of collagenase to treat glaucoma
WO2014134532A1 (en) * 2013-02-28 2014-09-04 Ventrix, Inc. Methods and compositions for tissue therapy and analysis
CN103340663B (zh) * 2013-06-17 2016-05-04 李宝童 囊式冠脉压迫装置及慢性心肌缺血动物模型制造方法
WO2018109733A2 (en) * 2016-12-15 2018-06-21 Luseed Vascular Ltd. Methods and devices for treating vascular related disorders
CN112638289A (zh) * 2018-06-28 2021-04-09 玛利塞生物技术公司 治疗血栓形成的药物组合物和方法以及医疗设备递送
US20220265291A9 (en) * 2018-06-28 2022-08-25 Marizyme, Inc. Pharmaceutical compositions and methods for the treatment of thrombosis and delivery by medical devices
CA3055856A1 (en) 2018-10-04 2020-04-04 Sunnybrook Research Institute Systems and methods for treating vascular occlusions with catheter based ultrasound
CN115245143B (zh) * 2022-07-06 2024-06-28 上海市中西医结合医院 一种动脉闭塞性疾病动物模型的构建方法

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US4636195A (en) * 1982-04-02 1987-01-13 Harvey Wolinsky Method and apparatus for removing arterial constriction
US5955584A (en) * 1986-03-31 1999-09-21 Charter Ventures Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
US5811248A (en) 1986-03-31 1998-09-22 Charter Ventures Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
US6025477A (en) 1986-03-31 2000-02-15 Calenoff; Emanuel Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
US5163421A (en) * 1988-01-22 1992-11-17 Angiosonics, Inc. In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging
US5024829A (en) * 1988-11-21 1991-06-18 Centocor, Inc. Method of imaging coronary thrombi
US5328470A (en) * 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
JPH05501855A (ja) * 1989-05-17 1993-04-08 リサーチ、コーポレーション、テクノロジーズ、インコーポレーテッド 哺乳動物における血栓症の治療に関する方法及び組成物
US5422261A (en) * 1993-04-16 1995-06-06 Baxter International Inc. Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells
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CN1327893C (zh) * 2001-10-01 2007-07-25 布雷德利 胶原酶在促进导线在完全动脉闭塞内通过中的应用

Also Published As

Publication number Publication date
EP1438065A2 (en) 2004-07-21
US8021660B2 (en) 2011-09-20
PT1438065E (pt) 2013-01-24
CA2462512C (en) 2013-11-05
JP2005503820A (ja) 2005-02-10
EP1438065B1 (en) 2012-11-21
AU2002328729B2 (en) 2009-07-16
US7425326B2 (en) 2008-09-16
IL161137A0 (en) 2004-08-31
IL161137A (en) 2014-08-31
CN1327893C (zh) 2007-07-25
US20050053548A1 (en) 2005-03-10
SI1438065T1 (sl) 2013-03-29
CA2462512A1 (en) 2003-04-10
US20070014783A1 (en) 2007-01-18
HK1076037A1 (en) 2006-01-06
WO2003028756A3 (en) 2003-08-28
US20090074744A1 (en) 2009-03-19
WO2003028756A2 (en) 2003-04-10
ES2396964T3 (es) 2013-03-01
AU2002328729A2 (en) 2003-04-14
AU2002328729C1 (en) 2009-11-26
CN1599621A (zh) 2005-03-23

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