DK143349C - Fremgangsmaade til udfoerelse af en enzymatisk reaktion og enzympraeparat til anvendelse hertil - Google Patents

Fremgangsmaade til udfoerelse af en enzymatisk reaktion og enzympraeparat til anvendelse hertil

Info

Publication number
DK143349C
DK143349C DK365275A DK365275A DK143349C DK 143349 C DK143349 C DK 143349C DK 365275 A DK365275 A DK 365275A DK 365275 A DK365275 A DK 365275A DK 143349 C DK143349 C DK 143349C
Authority
DK
Denmark
Prior art keywords
procedure
carrying
enzymatic reaction
enzyme preparation
enzyme
Prior art date
Application number
DK365275A
Other languages
Danish (da)
English (en)
Other versions
DK143349B (da
DK365275A (da
Inventor
R A G Smith
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of DK365275A publication Critical patent/DK365275A/da
Priority to DK123079A priority Critical patent/DK144737C/da
Publication of DK143349B publication Critical patent/DK143349B/da
Application granted granted Critical
Publication of DK143349C publication Critical patent/DK143349C/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/06—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing polymers
    • B01J31/061—Chiral polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/003—Catalysts comprising hydrides, coordination complexes or organic compounds containing enzymes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/06—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/096—Polyesters; Polyamides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
DK365275A 1974-08-13 1975-08-12 Fremgangsmaade til udfoerelse af en enzymatisk reaktion og enzympraeparat til anvendelse hertil DK143349C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK123079A DK144737C (da) 1974-08-13 1979-03-26 Fremgangsmaade til fremstilling af enzympraeparater

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB3555674 1974-08-13
GB3555674 1974-08-13
GB1743475A GB1463513A (en) 1974-08-13 1975-04-26 Enzymes
GB1743475 1975-04-26

Publications (3)

Publication Number Publication Date
DK365275A DK365275A (da) 1976-02-14
DK143349B DK143349B (da) 1981-08-10
DK143349C true DK143349C (da) 1981-12-07

Family

ID=26252681

Family Applications (1)

Application Number Title Priority Date Filing Date
DK365275A DK143349C (da) 1974-08-13 1975-08-12 Fremgangsmaade til udfoerelse af en enzymatisk reaktion og enzympraeparat til anvendelse hertil

Country Status (19)

Country Link
US (1) US4267273A (de)
JP (1) JPS5151582A (de)
AR (2) AR216891A1 (de)
AT (1) AT363889B (de)
AU (1) AU497573B2 (de)
BR (1) BR7505186A (de)
CA (1) CA1053595A (de)
CH (1) CH624431A5 (de)
DE (1) DE2535951A1 (de)
DK (1) DK143349C (de)
ES (1) ES440240A1 (de)
FI (1) FI752275A (de)
FR (1) FR2288748A1 (de)
GB (1) GB1463513A (de)
IE (1) IE41894B1 (de)
IL (1) IL47893A (de)
MX (1) MX2951E (de)
NL (1) NL7509667A (de)
SE (2) SE7509008L (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5548392A (en) 1978-02-17 1980-04-07 Toyo Jozo Co Ltd Novel immobilizing material combined with biologically active substance, its preparation, device comprising it, method, and preparation of support
SE416314B (sv) * 1978-04-03 1980-12-15 Svenska Sockerfabriks Ab Enzymatiskt forfarande, varvid enzymet foreligger i ett losligt komplex med hydrofob bindning och en del som modifierar enzymetsproduktivitetskinetiska egenskaper samt det losliga komplexet
DE2839737A1 (de) * 1978-09-13 1980-03-20 Roehm Gmbh Verfahren zur enzymatischen umsetzung mittels traegergebundener enzyme
DE2937964C2 (de) * 1979-09-20 1982-11-11 Peter 3400 Göttingen Schilling Mittel zur Bekämpfung der Karies
GB8334499D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Derivatives
US4632904A (en) * 1983-12-27 1986-12-30 Ciba Corning Diagnostics Corp. Immobilized enzyme composites having carriers derivatized with an organotitanate
US4795542A (en) * 1986-04-24 1989-01-03 St. Jude Medical, Inc. Electrochemical concentration detector device
DE3784592T2 (de) * 1986-08-07 1993-09-23 Minnesota Mining & Mfg Stabile, biologisch-aktive, fluorchemische emulsionen.
US4808530A (en) * 1986-09-05 1989-02-28 The Ohio State University Protein immobilization by adsorption of a hydrophobic amidine protein derivative to a hydrophobic surface
US4885250A (en) * 1987-03-02 1989-12-05 E. I. Du Pont De Nemours And Company Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports
EP0353953A3 (de) * 1988-08-04 1990-11-22 Imperial Chemical Industries Plc Verfahren zur Herstellung von Enzym katalysierter Reaktion
US5289855A (en) * 1988-10-14 1994-03-01 Elkay Manufacturing Co. Liquid container support and probe-type hygienic liquid dispensing system
US5295519A (en) * 1988-10-14 1994-03-22 Elkay Manufacturing Company Hygienic liquid dispensing system including feed tube or probe for opening and resealing coaxial cap
WO1990006996A1 (en) * 1988-12-19 1990-06-28 Sepracor, Inc. Method and apparatus for catalyst containment in multiphase membrane reactor systems
US5270193A (en) * 1989-10-27 1993-12-14 E. I. Dupont De Nemours And Company Immobilization of biomolecules on perfluorocarbon surfaces
ES2036149A6 (es) * 1989-12-12 1993-05-01 Consejo Superior Investigacion Procedimiento de sintesis de antibioticos semiestaticos en sistemas termodinamicamente controlados agua-cosolventes organicos miscibles apolares con el empleo de penicilina g acilasa.
US5288619A (en) * 1989-12-18 1994-02-22 Kraft General Foods, Inc. Enzymatic method for preparing transesterified oils
AU644199B2 (en) * 1990-08-10 1993-12-02 Holmwood Highgate (Aust) Pty Ltd Road tanker
US5182201A (en) * 1990-10-26 1993-01-26 Uop Lipase immobilization without covalent bonding on an amphiphilic support containing lipophilic alkyl chains
FI20105572A0 (fi) 2010-05-24 2010-05-24 Prevab R Lcc Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt
EP3132033B1 (de) 2014-04-17 2019-10-30 Synthetic Biologics, Inc. Beta-lactamasen mit verbesserten eigenschaften zur therapie
JP6803328B2 (ja) 2014-08-28 2021-01-06 シンセティック バイオロジクス，インコーポレイテッド 大腸菌ベースでのベータラクタマーゼ生産
JP6672277B2 (ja) 2014-10-08 2020-04-01 シンセティック・バイオロジクス・インコーポレイテッド ベータラクタマーゼ製剤およびその使用
WO2016105498A1 (en) 2014-12-23 2016-06-30 Synthetic Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
CN107530406B (zh) 2015-02-23 2021-10-22 合成生物制品有限公司 用于保护肠微生物群系的与抗生素一起使用的碳青霉烯酶
AU2016229976B2 (en) 2015-03-06 2021-11-11 Theriva Biologics, Inc. Safe and effective beta-lactamase dosing for microbiome protection
WO2020088510A1 (zh) * 2018-10-30 2020-05-07 武汉武药制药有限公司 一种(r)-邻氯扁桃酸的制备方法和用于该制备方法的一种循环式生物酶催化反应系统

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3706633A (en) * 1970-04-10 1972-12-19 Monsanto Co Preparation of water-insoluble enzyme derivatives
US3741871A (en) * 1972-01-04 1973-06-26 Monsanto Co Preparation of immobilized enzymes
GB1449808A (en) * 1972-11-21 1976-09-15 Beecham Group Ltd 6-aminopenicillanic acid preparation

Also Published As

Publication number Publication date
BR7505186A (pt) 1976-08-03
FI752275A (de) 1976-02-14
CH624431A5 (de) 1981-07-31
AU8394275A (en) 1977-02-17
GB1463513A (en) 1977-02-02
CA1053595A (en) 1979-05-01
AT363889B (de) 1981-09-10
NL7509667A (nl) 1976-02-17
SE8006247L (sv) 1980-09-08
DE2535951A1 (de) 1976-02-26
IE41894B1 (en) 1980-04-23
MX2951E (es) 1980-01-03
DK143349B (da) 1981-08-10
FR2288748B1 (de) 1979-05-25
ES440240A1 (es) 1978-06-01
ATA629375A (de) 1981-02-15
IL47893A0 (en) 1975-11-25
US4267273A (en) 1981-05-12
IE41894L (en) 1976-02-13
FR2288748A1 (fr) 1976-05-21
IL47893A (en) 1978-07-31
AU497573B2 (en) 1978-12-21
JPS5151582A (de) 1976-05-07
DK365275A (da) 1976-02-14
AR218089A1 (es) 1980-05-15
AR216891A1 (es) 1980-02-15
SE7509008L (sv) 1976-02-16

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