DK1432402T3 - Sammensætning til tilförsel af lægemiddelkombinationer - Google Patents
Sammensætning til tilförsel af lægemiddelkombinationerInfo
- Publication number
- DK1432402T3 DK1432402T3 DK02766997T DK02766997T DK1432402T3 DK 1432402 T3 DK1432402 T3 DK 1432402T3 DK 02766997 T DK02766997 T DK 02766997T DK 02766997 T DK02766997 T DK 02766997T DK 1432402 T3 DK1432402 T3 DK 1432402T3
- Authority
- DK
- Denmark
- Prior art keywords
- administration
- composition
- drug combinations
- combinations
- antagonistic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32667101P | 2001-10-03 | 2001-10-03 | |
US34152901P | 2001-12-17 | 2001-12-17 | |
US35675902P | 2002-02-15 | 2002-02-15 | |
CA002383259A CA2383259A1 (en) | 2002-04-23 | 2002-04-23 | Synergistic compositions |
US40198402P | 2002-08-07 | 2002-08-07 | |
US40873302P | 2002-09-06 | 2002-09-06 | |
PCT/CA2002/001500 WO2003028696A2 (en) | 2001-10-03 | 2002-10-03 | Compositions for delivery of drug combinations |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1432402T3 true DK1432402T3 (da) | 2007-03-26 |
Family
ID=32475852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02766997T DK1432402T3 (da) | 2001-10-03 | 2002-10-03 | Sammensætning til tilförsel af lægemiddelkombinationer |
Country Status (13)
Country | Link |
---|---|
EP (2) | EP1432402B1 (he) |
JP (2) | JP4778679B2 (he) |
AT (1) | ATE345775T1 (he) |
AU (1) | AU2002331480B2 (he) |
CA (1) | CA2462369C (he) |
CY (1) | CY1105953T1 (he) |
DE (1) | DE60216305T2 (he) |
DK (1) | DK1432402T3 (he) |
ES (1) | ES2272768T3 (he) |
HK (1) | HK1065714A1 (he) |
IL (2) | IL161214A (he) |
PT (1) | PT1432402E (he) |
WO (1) | WO2003028696A2 (he) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2383259A1 (en) | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
US7850990B2 (en) * | 2001-10-03 | 2010-12-14 | Celator Pharmaceuticals, Inc. | Compositions for delivery of drug combinations |
WO2004087115A2 (en) * | 2003-04-02 | 2004-10-14 | Celator Pharmaceuticals, Inc. | Combination compositions of camptothecins and fluoropyrimidines |
US20060193902A1 (en) * | 2003-04-02 | 2006-08-31 | Celator Pharmaceuticals, Inc. | Pharmaceutical compositions containing active agents having a lactone group and transition metal ions |
WO2004087105A1 (en) * | 2003-04-02 | 2004-10-14 | Celator Pharmaceuticals, Inc. | Combination formulations of platinum agents and fluoropyrimidines |
UA85099C2 (en) | 2004-06-01 | 2008-12-25 | Кабусики Кайся Якулт Хонса | Liposomal irinotecan preparation |
WO2006014626A2 (en) | 2004-07-19 | 2006-02-09 | Celator Pharmaceuticals, Inc. | Partuculate constructs for release of active agents |
WO2006032136A1 (en) * | 2004-09-20 | 2006-03-30 | British Columbia Cancer Agency Branch | Free or liposomal gemcitabine alone or in combination with free or liposomal idarubicin |
CA2582949A1 (en) | 2004-10-06 | 2006-04-13 | Bc Cancer Agency | Liposomes with improved drug retention for treatment of cancer |
JP5815915B2 (ja) * | 2005-10-11 | 2015-11-17 | ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション | 過活動膀胱障害の治療のためのスフィンゴミエリンリポソーム |
US7842676B2 (en) | 2005-10-25 | 2010-11-30 | Celator Pharmaceuticals, Inc. | Fixed ratio drug combination treatments for solid tumors |
WO2007076117A2 (en) * | 2005-12-22 | 2007-07-05 | Celator Pharmaceuticals, Inc. | Liposomal formulations comprising secondary and tertiary amines and methods for preparing thereof |
US20090263398A1 (en) * | 2006-07-14 | 2009-10-22 | Astex Therapeutics Limited | Pharmaceutical combinations |
WO2008106129A2 (en) * | 2007-02-26 | 2008-09-04 | Wisconsin Alumni Research Foundation | Polymeric micelles for combination drug delivery |
JP2010536738A (ja) * | 2007-08-16 | 2010-12-02 | バイオコンパティブルズ ユーケー リミテッド | 薬剤の組み合わせの送達 |
EP2222278B1 (en) | 2007-11-28 | 2015-04-08 | Celator Pharmaceuticals, Inc. | Improved taxane delivery system |
CL2009000647A1 (es) * | 2008-04-04 | 2010-06-04 | Chugai Pharmaceutical Co Ltd | Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto. |
US20110223241A1 (en) | 2008-10-16 | 2011-09-15 | Celator Pharmaceuticals, Inc. | Combination methods and compositions |
MA40764A (fr) | 2014-09-26 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Agent thérapeutique induisant une cytotoxicité |
US9895313B2 (en) * | 2015-03-03 | 2018-02-20 | Cureport, Inc. | Combination liposomal pharmaceutical formulations |
MA42458A (fr) * | 2015-07-15 | 2018-05-23 | Celator Pharmaceuticals Inc | Systèmes améliorés d'administration de nanoparticules |
CN105434437B (zh) * | 2015-12-01 | 2018-03-02 | 山东大学 | 一种奥沙利铂和伊立替康类药物共载脂质体及其制备方法 |
CN106619509B (zh) * | 2016-12-21 | 2020-02-18 | 山东大学 | 一种奥沙利铂和伊立替康共载载药脂肪乳及其制备方法 |
WO2021183318A2 (en) * | 2020-03-09 | 2021-09-16 | President And Fellows Of Harvard College | Methods and compositions relating to improved combination therapies |
US11980636B2 (en) | 2020-11-18 | 2024-05-14 | Jazz Pharmaceuticals Ireland Limited | Treatment of hematological disorders |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL26210A (en) * | 1965-08-02 | 1970-12-24 | Merck & Co Inc | Pharmaceutical compositions containing substituted sulphoxides |
JP3213471B2 (ja) * | 1994-04-13 | 2001-10-02 | ポーラ化成工業株式会社 | 薬効成分含有リポソーム製剤の製造方法 |
JP5124066B2 (ja) * | 1999-03-24 | 2013-01-23 | イギリス国 | ポリカチオン性炭水化物のワクチンにおける免疫賦活剤としての使用 |
AU777620B2 (en) * | 1999-04-09 | 2004-10-21 | Jessie L.S. Au | Methods and compositions for enhancing delivery of therapeutic agents to tissues |
EP1206234A4 (en) * | 1999-06-03 | 2005-06-01 | Jessie L S Au | METHODS AND COMPOSITIONS FOR MODULATING PROLIFERATION AND CELL DEATH |
US6352996B1 (en) * | 1999-08-03 | 2002-03-05 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
BR0013866A (pt) * | 1999-09-09 | 2002-05-14 | Univ California | Distribuição de lipossomas catiÈnicos de taxanos aos vasos sanguineos angiogênicos |
JP2003511404A (ja) * | 1999-10-14 | 2003-03-25 | 1170535 オンタリオ インコーポレーテッド | リポソーム内包銀塩組成物 |
US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
ES2230268T3 (es) * | 2000-02-10 | 2005-05-01 | Liplasome Pharma A/S | Sistema de liberacion de farmacos basados en lipidos. |
AU2001249393A1 (en) * | 2000-03-22 | 2001-10-03 | Glaxo Group Limited | Pharmaceutical comprising an agent that blocks the cell cycle and an antibody |
-
2002
- 2002-10-03 AT AT02766997T patent/ATE345775T1/de active
- 2002-10-03 AU AU2002331480A patent/AU2002331480B2/en not_active Expired
- 2002-10-03 EP EP02766997A patent/EP1432402B1/en not_active Expired - Lifetime
- 2002-10-03 ES ES02766997T patent/ES2272768T3/es not_active Expired - Lifetime
- 2002-10-03 DE DE60216305T patent/DE60216305T2/de not_active Expired - Lifetime
- 2002-10-03 PT PT02766997T patent/PT1432402E/pt unknown
- 2002-10-03 JP JP2003532029A patent/JP4778679B2/ja not_active Expired - Lifetime
- 2002-10-03 CA CA002462369A patent/CA2462369C/en not_active Expired - Lifetime
- 2002-10-03 WO PCT/CA2002/001500 patent/WO2003028696A2/en active Application Filing
- 2002-10-03 DK DK02766997T patent/DK1432402T3/da active
- 2002-10-03 EP EP06009230A patent/EP1693052A1/en not_active Withdrawn
-
2004
- 2004-04-01 IL IL161214A patent/IL161214A/he active IP Right Grant
- 2004-11-10 HK HK04108630A patent/HK1065714A1/xx not_active IP Right Cessation
-
2007
- 2007-01-25 CY CY20071100100T patent/CY1105953T1/el unknown
-
2008
- 2008-01-15 IL IL188774A patent/IL188774A0/en unknown
-
2010
- 2010-02-19 JP JP2010034701A patent/JP4926256B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CY1105953T1 (el) | 2011-04-06 |
EP1693052A1 (en) | 2006-08-23 |
CA2462369C (en) | 2009-12-22 |
WO2003028696A8 (en) | 2006-09-08 |
JP4778679B2 (ja) | 2011-09-21 |
DE60216305D1 (de) | 2007-01-04 |
IL161214A (he) | 2008-06-05 |
JP4926256B2 (ja) | 2012-05-09 |
ES2272768T3 (es) | 2007-05-01 |
JP2005508920A (ja) | 2005-04-07 |
WO2003028696A2 (en) | 2003-04-10 |
IL188774A0 (en) | 2008-04-13 |
CA2462369A1 (en) | 2003-04-10 |
JP2010180210A (ja) | 2010-08-19 |
HK1065714A1 (en) | 2005-03-04 |
WO2003028696A3 (en) | 2003-07-31 |
AU2002331480B2 (en) | 2007-10-25 |
EP1432402B1 (en) | 2006-11-22 |
PT1432402E (pt) | 2007-02-28 |
ATE345775T1 (de) | 2006-12-15 |
EP1432402A2 (en) | 2004-06-30 |
DE60216305T2 (de) | 2007-07-05 |
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