DK142874B - Analogifremgangsmåde til fremstilling af dihydrolysergsyrederivater eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af dihydrolysergsyrederivater eller syreadditionssalte deraf. Download PDF

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Publication number
DK142874B
DK142874B DK238571A DK238571A DK142874B DK 142874 B DK142874 B DK 142874B DK 238571 A DK238571 A DK 238571A DK 238571 A DK238571 A DK 238571A DK 142874 B DK142874 B DK 142874B
Authority
DK
Denmark
Prior art keywords
acid
methyl
preparation
compound
dihydro
Prior art date
Application number
DK238571A
Other languages
Danish (da)
English (en)
Other versions
DK142874C (ja
Inventor
Tibor Balogh
Lajos Wolf
Jozsef Borsi
Erzsebet Mago
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to DK583874A priority Critical patent/DK139068B/da
Publication of DK142874B publication Critical patent/DK142874B/da
Application granted granted Critical
Publication of DK142874C publication Critical patent/DK142874C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C07D457/08—Lysergic acid amides in which the amide nitrogen is a member of a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK238571A 1970-05-18 1971-05-17 Analogifremgangsmåde til fremstilling af dihydrolysergsyrederivater eller syreadditionssalte deraf. DK142874B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK583874A DK139068B (da) 1970-05-18 1974-11-08 Fremgangsmåde til fremstilling af dihydrolysergsyre- og -isolysergsyreforbindelser eller syreadditionssalte deraf.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUGO001135 1970-05-18
HUGO001135 1970-05-18

Publications (2)

Publication Number Publication Date
DK142874B true DK142874B (da) 1981-02-16
DK142874C DK142874C (ja) 1981-09-28

Family

ID=10996683

Family Applications (1)

Application Number Title Priority Date Filing Date
DK238571A DK142874B (da) 1970-05-18 1971-05-17 Analogifremgangsmåde til fremstilling af dihydrolysergsyrederivater eller syreadditionssalte deraf.

Country Status (12)

Country Link
JP (1) JPS5634598B1 (ja)
AT (1) AT347047B (ja)
CA (1) CA924306A (ja)
CH (2) CH590277A5 (ja)
CS (1) CS179371B2 (ja)
DE (1) DE2124640C2 (ja)
DK (1) DK142874B (ja)
GB (1) GB1345546A (ja)
NL (1) NL172825C (ja)
SE (2) SE396753B (ja)
SU (1) SU400091A3 (ja)
YU (1) YU35770B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU169073B (ja) * 1974-05-28 1976-09-28
US4064249A (en) * 1974-05-28 1977-12-20 Richter Gedeon Vegyeszeti Gyar Rt. Compounds with ergoline skeleton
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
NL189462C (nl) * 1980-04-03 1993-04-16 Erba Carlo Spa Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan.
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors
US4914107A (en) * 1989-01-17 1990-04-03 Eli Lilly And Company Method for selectively blocking 5-HT2 receptors
US5441961A (en) * 1992-08-27 1995-08-15 Eli Lilly And Company Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines
BR112017015487A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
WO2018223065A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT192546B (de) * 1956-02-27 1957-10-25 Anton Von Waldheim Chemisch Ph Verfahren zur Herstellung von Dihydrolysergsäure und deren Derivaten

Also Published As

Publication number Publication date
SE396753B (sv) 1977-10-03
DE2124640A1 (de) 1972-11-02
CS179371B2 (en) 1977-10-31
CA924306A (en) 1973-04-10
GB1345546A (en) 1974-01-30
DK142874C (ja) 1981-09-28
SU400091A3 (ja) 1973-10-03
JPS5634598B1 (ja) 1981-08-11
NL172825C (nl) 1983-11-01
CH590277A5 (ja) 1977-07-29
CH567506A5 (ja) 1975-10-15
YU122971A (en) 1980-10-31
SE416302B (sv) 1980-12-15
YU35770B (en) 1981-06-30
NL172825B (nl) 1983-06-01
DE2124640C2 (de) 1983-02-03
NL7106834A (ja) 1971-11-22
ATA428771A (de) 1978-04-15
AT347047B (de) 1978-12-11

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