CS179371B2 - Method for preparation of new derivatives of dihydrolysergic acid and dihydroisolysergic acid. - Google Patents

Method for preparation of new derivatives of dihydrolysergic acid and dihydroisolysergic acid.

Info

Publication number
CS179371B2
CS179371B2 CS359871A CS359871A CS179371B2 CS 179371 B2 CS179371 B2 CS 179371B2 CS 359871 A CS359871 A CS 359871A CS 359871 A CS359871 A CS 359871A CS 179371 B2 CS179371 B2 CS 179371B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
preparation
dihydroisolysergic
new derivatives
dihydrolysergic
Prior art date
Application number
CS359871A
Other languages
Czech (cs)
English (en)
Inventor
Erzsebet Mago
Jozsef Borsi
Tibor Balogh
Lajos Wolf
Original Assignee
Erzsebet Mago
Jozsef Borsi
Tibor Balogh
Lajos Wolf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erzsebet Mago, Jozsef Borsi, Tibor Balogh, Lajos Wolf filed Critical Erzsebet Mago
Publication of CS179371B2 publication Critical patent/CS179371B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06Lysergic acid amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06Lysergic acid amides
    • C07D457/08Lysergic acid amides in which the amide nitrogen is a member of a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS359871A 1970-05-18 1971-05-18 Method for preparation of new derivatives of dihydrolysergic acid and dihydroisolysergic acid. CS179371B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO001135 1970-05-18

Publications (1)

Publication Number Publication Date
CS179371B2 true CS179371B2 (en) 1977-10-31

Family

ID=10996683

Family Applications (1)

Application Number Title Priority Date Filing Date
CS359871A CS179371B2 (en) 1970-05-18 1971-05-18 Method for preparation of new derivatives of dihydrolysergic acid and dihydroisolysergic acid.

Country Status (12)

Country Link
JP (1) JPS5634598B1 (ja)
AT (1) AT347047B (ja)
CA (1) CA924306A (ja)
CH (2) CH590277A5 (ja)
CS (1) CS179371B2 (ja)
DE (1) DE2124640C2 (ja)
DK (1) DK142874B (ja)
GB (1) GB1345546A (ja)
NL (1) NL172825C (ja)
SE (2) SE396753B (ja)
SU (1) SU400091A3 (ja)
YU (1) YU35770B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064249A (en) * 1974-05-28 1977-12-20 Richter Gedeon Vegyeszeti Gyar Rt. Compounds with ergoline skeleton
HU169073B (ja) * 1974-05-28 1976-09-28
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
NL189462C (nl) * 1980-04-03 1993-04-16 Erba Carlo Spa Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan.
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors
US4914107A (en) * 1989-01-17 1990-04-03 Eli Lilly And Company Method for selectively blocking 5-HT2 receptors
US5441961A (en) * 1992-08-27 1995-08-15 Eli Lilly And Company Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines
JP6856532B2 (ja) 2015-01-20 2021-04-07 エックスオーシー ファーマシューティカルズ インコーポレイテッドXoc Pharmaceuticals, Inc エルゴリン化合物およびその使用
BR112017015510A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo
MX2019014272A (es) 2017-06-01 2020-12-11 Xoc Pharmaceuticals Inc Compuestos policiclicos y usos de los mismos.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT192546B (de) * 1956-02-27 1957-10-25 Anton Von Waldheim Chemisch Ph Verfahren zur Herstellung von Dihydrolysergsäure und deren Derivaten

Also Published As

Publication number Publication date
YU122971A (en) 1980-10-31
GB1345546A (en) 1974-01-30
DK142874C (ja) 1981-09-28
YU35770B (en) 1981-06-30
AT347047B (de) 1978-12-11
DE2124640A1 (de) 1972-11-02
CA924306A (en) 1973-04-10
SE416302B (sv) 1980-12-15
DK142874B (da) 1981-02-16
ATA428771A (de) 1978-04-15
SE396753B (sv) 1977-10-03
SU400091A3 (ja) 1973-10-03
DE2124640C2 (de) 1983-02-03
JPS5634598B1 (ja) 1981-08-11
CH567506A5 (ja) 1975-10-15
NL172825C (nl) 1983-11-01
CH590277A5 (ja) 1977-07-29
NL172825B (nl) 1983-06-01
NL7106834A (ja) 1971-11-22

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