DK140724B - Analogifremgangsmåde til fremstilling af 3-fluor-6-(4-methyl-1-piperazinyl)morphanthridin. - Google Patents

Analogifremgangsmåde til fremstilling af 3-fluor-6-(4-methyl-1-piperazinyl)morphanthridin.

Info

Publication number
DK140724B
DK140724B DK485677AA DK485677A DK140724B DK 140724 B DK140724 B DK 140724B DK 485677A A DK485677A A DK 485677AA DK 485677 A DK485677 A DK 485677A DK 140724 B DK140724 B DK 140724B
Authority
DK
Denmark
Prior art keywords
morphanthridine
piperazinyl
fluoro
methyl
preparation
Prior art date
Application number
DK485677AA
Other languages
Danish (da)
English (en)
Other versions
DK485677A (OSRAM
DK140724C (OSRAM
Inventor
Fritz Hunziker
Rudolf Fischer
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK485677A publication Critical patent/DK485677A/da
Publication of DK140724B publication Critical patent/DK140724B/da
Application granted granted Critical
Publication of DK140724C publication Critical patent/DK140724C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK485677AA 1976-11-10 1977-11-01 Analogifremgangsmåde til fremstilling af 3-fluor-6-(4-methyl-1-piperazinyl)morphanthridin. DK140724B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1415776A CH624682A5 (OSRAM) 1976-11-10 1976-11-10

Publications (3)

Publication Number Publication Date
DK485677A DK485677A (OSRAM) 1978-05-11
DK140724B true DK140724B (da) 1979-11-05
DK140724C DK140724C (OSRAM) 1980-03-31

Family

ID=4398460

Family Applications (1)

Application Number Title Priority Date Filing Date
DK485677AA DK140724B (da) 1976-11-10 1977-11-01 Analogifremgangsmåde til fremstilling af 3-fluor-6-(4-methyl-1-piperazinyl)morphanthridin.

Country Status (26)

Country Link
US (1) US4308207A (OSRAM)
JP (1) JPS5929076B2 (OSRAM)
AT (1) AT366682B (OSRAM)
AU (1) AU517829B2 (OSRAM)
BE (1) BE860613A (OSRAM)
CA (1) CA1086315A (OSRAM)
CH (1) CH624682A5 (OSRAM)
CY (1) CY1269A (OSRAM)
DE (1) DE2748920C2 (OSRAM)
DK (1) DK140724B (OSRAM)
ES (1) ES463971A1 (OSRAM)
FI (1) FI64143C (OSRAM)
FR (1) FR2370745A1 (OSRAM)
GB (2) GB1592329A (OSRAM)
HK (1) HK32282A (OSRAM)
IE (1) IE46262B1 (OSRAM)
IL (1) IL53332A (OSRAM)
KE (1) KE3472A (OSRAM)
MY (1) MY8400056A (OSRAM)
NL (1) NL175297C (OSRAM)
NZ (2) NZ185642A (OSRAM)
PH (1) PH13515A (OSRAM)
PT (1) PT67247B (OSRAM)
SE (1) SE435510B (OSRAM)
SG (1) SG66584G (OSRAM)
SU (1) SU686616A1 (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3402060A1 (de) * 1984-01-21 1985-08-01 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
JPH05506249A (ja) * 1990-10-10 1993-09-16 シェリング・コーポレーション ビスーベンゾシクロヘプタピペリジリデン、ピペリジンおよびピペラジン化合物、組成物および使用法
GEP20001939B (en) * 1992-01-17 2000-02-05 Angelini Ricerca S P A Soc Consortile Alkyl Derivatives of Trazodone with CNS Activity
ES2153373T3 (es) * 1992-05-29 2001-03-01 Lilly Co Eli Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central.
CN1681388A (zh) * 2002-09-18 2005-10-12 Fmc有限公司 三环衍生物杀虫剂
EP1589974A2 (en) * 2003-01-23 2005-11-02 Acadia Pharmaceuticals Inc. Use of n-desmethylclozapine to treat human neuropsychiatric disease
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
PL1696931T3 (pl) * 2003-12-22 2009-10-30 Acadia Pharm Inc Aminopodstawione analogi diarylo[A,D]cykloheptenowe jako agoniści receptorów muskarynowych i sposoby leczenia chorób neuropsychiatrycznych
RU2006138497A (ru) * 2004-04-01 2008-05-10 Акадиа Фармасьютикалз Инк. (Us) Кристаллические формы n-десметилклозапина
US20070105836A1 (en) * 2005-10-31 2007-05-10 Lars Pettersson Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL140242B (nl) * 1963-03-01 1973-11-15 Wander Ag Dr A Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen.
US3389139A (en) * 1963-06-14 1968-06-18 Wander Ag Dr A 6-homopiperazino and piperazinomorphanthridines
GB1006156A (en) * 1963-06-14 1965-09-29 Wander Ag Dr A 6-basic substituted morphanthridines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US3962248A (en) * 1972-04-04 1976-06-08 Sandoz, Inc. Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
CH601287A5 (OSRAM) * 1975-08-06 1978-07-14 Sandoz Ag

Also Published As

Publication number Publication date
SG66584G (en) 1985-03-15
AT366682B (de) 1982-04-26
IL53332A0 (en) 1978-01-31
NL175297C (nl) 1984-10-16
FR2370745A1 (fr) 1978-06-09
AU517829B2 (en) 1981-08-27
CA1086315A (en) 1980-09-23
KE3472A (en) 1984-11-09
SU686616A3 (ru) 1979-09-15
NL7712171A (nl) 1978-05-12
SU686616A1 (en) 1979-09-15
FI773273A7 (fi) 1978-05-11
MY8400056A (en) 1984-12-31
ES463971A1 (es) 1978-12-01
BE860613A (fr) 1978-05-08
JPS5929076B2 (ja) 1984-07-18
HK32282A (en) 1982-07-23
PT67247A (en) 1977-12-01
IL53332A (en) 1981-11-30
CY1269A (en) 1984-11-23
PT67247B (en) 1979-11-12
DE2748920A1 (de) 1978-05-11
PH13515A (en) 1980-06-03
DK485677A (OSRAM) 1978-05-11
NL175297B (nl) 1984-05-16
ATA799177A (de) 1981-09-15
DK140724C (OSRAM) 1980-03-31
NZ191043A (en) 1980-09-12
IE46262L (en) 1978-05-10
FI64143C (fi) 1983-10-10
AU3046777A (en) 1979-05-17
SE7712387L (sv) 1978-05-11
FI64143B (fi) 1983-06-30
NZ185642A (en) 1980-09-12
DE2748920C2 (de) 1982-12-02
FR2370745B1 (OSRAM) 1980-08-22
US4308207A (en) 1981-12-29
JPS5359686A (en) 1978-05-29
SE435510B (sv) 1984-10-01
CH624682A5 (OSRAM) 1981-08-14
GB1592329A (en) 1981-07-08
GB1592330A (en) 1981-07-08
IE46262B1 (en) 1983-04-20

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