DK140635B - Fremgangsmåde til fremstilling ag 1-(tetrahydro-2-furyl)-5-fluoruracil, 1,3-bis-(tetrahydro)-2-furyl)-5-fluoruracil eller en blanding deraf. - Google Patents

Fremgangsmåde til fremstilling ag 1-(tetrahydro-2-furyl)-5-fluoruracil, 1,3-bis-(tetrahydro)-2-furyl)-5-fluoruracil eller en blanding deraf.

Info

Publication number
DK140635B
DK140635B DK528576AA DK528576A DK140635B DK 140635 B DK140635 B DK 140635B DK 528576A A DK528576A A DK 528576AA DK 528576 A DK528576 A DK 528576A DK 140635 B DK140635 B DK 140635B
Authority
DK
Denmark
Prior art keywords
fluorouracil
furyl
tetrahydro
bis
mixture
Prior art date
Application number
DK528576AA
Other languages
Danish (da)
English (en)
Other versions
DK140635C (no
DK528576A (no
Inventor
Isao Minami
Yoshio Yoshioka
Hiroaki Nomura
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14271775A external-priority patent/JPS5268188A/ja
Priority claimed from JP526076A external-priority patent/JPS5289679A/ja
Priority claimed from JP8386376A external-priority patent/JPS539778A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK528576A publication Critical patent/DK528576A/da
Publication of DK140635B publication Critical patent/DK140635B/da
Application granted granted Critical
Publication of DK140635C publication Critical patent/DK140635C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK528576AA 1975-11-28 1976-11-24 Fremgangsmåde til fremstilling ag 1-(tetrahydro-2-furyl)-5-fluoruracil, 1,3-bis-(tetrahydro)-2-furyl)-5-fluoruracil eller en blanding deraf. DK140635B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP14271775A JPS5268188A (en) 1975-11-28 1975-11-28 Preparation of 1-(tetrahydro-2-furyl)-5-fluorouracil
JP526076A JPS5289679A (en) 1976-01-19 1976-01-19 Preparation of 5-fluorouracil derivatives
JP8386376A JPS539778A (en) 1976-07-13 1976-07-13 Preparation of 5-fluorouracil derivativds

Publications (3)

Publication Number Publication Date
DK528576A DK528576A (no) 1977-05-29
DK140635B true DK140635B (da) 1979-10-15
DK140635C DK140635C (no) 1980-03-10

Family

ID=27276677

Family Applications (1)

Application Number Title Priority Date Filing Date
DK528576AA DK140635B (da) 1975-11-28 1976-11-24 Fremgangsmåde til fremstilling ag 1-(tetrahydro-2-furyl)-5-fluoruracil, 1,3-bis-(tetrahydro)-2-furyl)-5-fluoruracil eller en blanding deraf.

Country Status (23)

Country Link
US (1) US4249006A (no)
AT (1) AT346858B (no)
AU (1) AU501833B2 (no)
BE (1) BE848662A (no)
CA (1) CA1122983A (no)
CH (1) CH616936A5 (no)
DE (1) DE2653398C2 (no)
DK (1) DK140635B (no)
FR (1) FR2332991A1 (no)
GB (1) GB1570219A (no)
GR (1) GR62855B (no)
HK (1) HK11283A (no)
HU (1) HU176890B (no)
IE (1) IE45046B1 (no)
MX (1) MX3873E (no)
MY (1) MY8400088A (no)
NL (1) NL7613285A (no)
NO (1) NO144887C (no)
PH (1) PH12998A (no)
PL (1) PL104613B1 (no)
PT (1) PT65883B (no)
SE (1) SE423389B (no)
SG (1) SG783G (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2526289A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising 5-fluorouracil or a derivative thereof and a liposomal platinum complex
CN103159746B (zh) * 2011-12-12 2015-09-02 山东新时代药业有限公司 一种工业法合成替加氟的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695297C3 (de) * 1968-01-10 1978-12-07 Institut Organitscheskogo Sinteza, Riga (Sowjetunion) 5-Fluor-l-(2-tetrahydrofuryl)-uracil und dessen Alkal'imetaUsalze, Verfahren zu deren Herstellung und diese enthaltende Mittel
US3912734A (en) * 1972-11-20 1975-10-14 Solomon Aronovich Giller Method for preparing N{HD 1{B -(2{40 -furanidyl)-and N{HD 1{B -2(2{40 -pyranidyl) uracils
US3960864A (en) * 1974-05-06 1976-06-01 The University Of Utah Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil
DE2519079A1 (de) * 1975-04-29 1976-11-11 Inst Orch Sintesa Akademii Nau Verfahren zur herstellung von n tief 1-(2'-furanicyl)-5-substituierten uracilen
JPS5259174A (en) * 1975-11-10 1977-05-16 Asahi Chem Ind Co Ltd Preparation of n-substituted uracil compounds

Also Published As

Publication number Publication date
IE45046L (en) 1977-05-28
HK11283A (en) 1983-03-24
GB1570219A (en) 1980-06-25
HU176890B (en) 1981-05-28
IE45046B1 (en) 1982-06-16
SE7613305L (sv) 1977-05-29
SG783G (en) 1983-09-09
CH616936A5 (no) 1980-04-30
FR2332991B1 (no) 1980-03-21
DE2653398C2 (de) 1986-07-17
PT65883A (en) 1976-12-01
MY8400088A (en) 1984-12-31
AT346858B (de) 1978-11-27
DE2653398A1 (de) 1977-06-08
BE848662A (fr) 1977-05-23
NO144887C (no) 1981-12-02
PH12998A (en) 1979-10-29
SE423389B (sv) 1982-05-03
GR62855B (en) 1979-06-23
DK140635C (no) 1980-03-10
CA1122983A (en) 1982-05-04
AU501833B2 (en) 1979-06-28
ATA874876A (de) 1978-04-15
US4249006A (en) 1981-02-03
PL104613B1 (pl) 1979-08-31
FR2332991A1 (fr) 1977-06-24
DK528576A (no) 1977-05-29
NO144887B (no) 1981-08-24
PT65883B (en) 1978-10-12
AU1965576A (en) 1978-05-25
NO764048L (no) 1977-06-01
MX3873E (es) 1981-08-26
NL7613285A (nl) 1977-06-01

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Legal Events

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