AT346858B - Verfahren zur herstellung von 1-(tetrahydro-2- furyl)-5-fluoruracil und/oder 1,3-bis(tetrahydro-2-furyl)-5-fluoruracil - Google Patents
Verfahren zur herstellung von 1-(tetrahydro-2- furyl)-5-fluoruracil und/oder 1,3-bis(tetrahydro-2-furyl)-5-fluoruracilInfo
- Publication number
- AT346858B AT346858B AT874876A AT874876A AT346858B AT 346858 B AT346858 B AT 346858B AT 874876 A AT874876 A AT 874876A AT 874876 A AT874876 A AT 874876A AT 346858 B AT346858 B AT 346858B
- Authority
- AT
- Austria
- Prior art keywords
- fluoruracil
- furyl
- tetrahydro
- bis
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14271775A JPS5268188A (en) | 1975-11-28 | 1975-11-28 | Preparation of 1-(tetrahydro-2-furyl)-5-fluorouracil |
| JP526076A JPS5289679A (en) | 1976-01-19 | 1976-01-19 | Preparation of 5-fluorouracil derivatives |
| JP8386376A JPS539778A (en) | 1976-07-13 | 1976-07-13 | Preparation of 5-fluorouracil derivativds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA874876A ATA874876A (de) | 1978-04-15 |
| AT346858B true AT346858B (de) | 1978-11-27 |
Family
ID=27276677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT874876A AT346858B (de) | 1975-11-28 | 1976-11-25 | Verfahren zur herstellung von 1-(tetrahydro-2- furyl)-5-fluoruracil und/oder 1,3-bis(tetrahydro-2-furyl)-5-fluoruracil |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4249006A (de) |
| AT (1) | AT346858B (de) |
| AU (1) | AU501833B2 (de) |
| BE (1) | BE848662A (de) |
| CA (1) | CA1122983A (de) |
| CH (1) | CH616936A5 (de) |
| DE (1) | DE2653398C2 (de) |
| DK (1) | DK140635B (de) |
| FR (1) | FR2332991A1 (de) |
| GB (1) | GB1570219A (de) |
| GR (1) | GR62855B (de) |
| HK (1) | HK11283A (de) |
| HU (1) | HU176890B (de) |
| IE (1) | IE45046B1 (de) |
| MX (1) | MX3873E (de) |
| MY (1) | MY8400088A (de) |
| NL (1) | NL7613285A (de) |
| NO (1) | NO144887C (de) |
| PH (1) | PH12998A (de) |
| PL (1) | PL104613B1 (de) |
| PT (1) | PT65883B (de) |
| SE (1) | SE423389B (de) |
| SG (1) | SG783G (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2526289A1 (en) * | 2003-05-20 | 2004-12-02 | Aronex Pharmaceuticals, Inc. | Combination chemotherapy comprising 5-fluorouracil or a derivative thereof and a liposomal platinum complex |
| CN103159746B (zh) * | 2011-12-12 | 2015-09-02 | 山东新时代药业有限公司 | 一种工业法合成替加氟的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1695297C3 (de) * | 1968-01-10 | 1978-12-07 | Institut Organitscheskogo Sinteza, Riga (Sowjetunion) | 5-Fluor-l-(2-tetrahydrofuryl)-uracil und dessen Alkal'imetaUsalze, Verfahren zu deren Herstellung und diese enthaltende Mittel |
| US3912734A (en) * | 1972-11-20 | 1975-10-14 | Solomon Aronovich Giller | Method for preparing N{HD 1{B -(2{40 -furanidyl)-and N{HD 1{B -2(2{40 -pyranidyl) uracils |
| US3960864A (en) * | 1974-05-06 | 1976-06-01 | The University Of Utah | Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil |
| DE2519079A1 (de) * | 1975-04-29 | 1976-11-11 | Inst Orch Sintesa Akademii Nau | Verfahren zur herstellung von n tief 1-(2'-furanicyl)-5-substituierten uracilen |
| JPS5259174A (en) * | 1975-11-10 | 1977-05-16 | Asahi Chem Ind Co Ltd | Preparation of n-substituted uracil compounds |
-
1976
- 1976-11-04 IE IE2461/76A patent/IE45046B1/en unknown
- 1976-11-05 GR GR52112A patent/GR62855B/el unknown
- 1976-11-05 CA CA265,062A patent/CA1122983A/en not_active Expired
- 1976-11-08 CH CH1402276A patent/CH616936A5/fr not_active IP Right Cessation
- 1976-11-12 GB GB47197/76A patent/GB1570219A/en not_active Expired
- 1976-11-15 FR FR7634249A patent/FR2332991A1/fr active Granted
- 1976-11-15 AU AU19655/76A patent/AU501833B2/en not_active Expired
- 1976-11-23 BE BE6045773A patent/BE848662A/xx not_active IP Right Cessation
- 1976-11-24 US US05/744,929 patent/US4249006A/en not_active Expired - Lifetime
- 1976-11-24 DK DK528576AA patent/DK140635B/da not_active IP Right Cessation
- 1976-11-24 MX MX765150U patent/MX3873E/es unknown
- 1976-11-24 DE DE2653398A patent/DE2653398C2/de not_active Expired
- 1976-11-24 PL PL1976193890A patent/PL104613B1/pl unknown
- 1976-11-24 PT PT65883A patent/PT65883B/pt unknown
- 1976-11-25 AT AT874876A patent/AT346858B/de not_active IP Right Cessation
- 1976-11-26 HU HU76TA1418A patent/HU176890B/hu unknown
- 1976-11-26 SE SE7613305A patent/SE423389B/xx not_active IP Right Cessation
- 1976-11-26 NO NO764048A patent/NO144887C/no unknown
- 1976-11-26 PH PH19171A patent/PH12998A/en unknown
- 1976-11-29 NL NL7613285A patent/NL7613285A/xx not_active Application Discontinuation
-
1983
- 1983-01-10 SG SG7/83A patent/SG783G/en unknown
- 1983-03-24 HK HK112/83A patent/HK11283A/xx unknown
-
1984
- 1984-12-30 MY MY88/84A patent/MY8400088A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE45046L (en) | 1977-05-28 |
| HK11283A (en) | 1983-03-24 |
| GB1570219A (en) | 1980-06-25 |
| HU176890B (en) | 1981-05-28 |
| IE45046B1 (en) | 1982-06-16 |
| SE7613305L (sv) | 1977-05-29 |
| SG783G (en) | 1983-09-09 |
| CH616936A5 (de) | 1980-04-30 |
| FR2332991B1 (de) | 1980-03-21 |
| DE2653398C2 (de) | 1986-07-17 |
| PT65883A (en) | 1976-12-01 |
| MY8400088A (en) | 1984-12-31 |
| DE2653398A1 (de) | 1977-06-08 |
| BE848662A (fr) | 1977-05-23 |
| NO144887C (no) | 1981-12-02 |
| PH12998A (en) | 1979-10-29 |
| SE423389B (sv) | 1982-05-03 |
| GR62855B (en) | 1979-06-23 |
| DK140635C (de) | 1980-03-10 |
| CA1122983A (en) | 1982-05-04 |
| AU501833B2 (en) | 1979-06-28 |
| ATA874876A (de) | 1978-04-15 |
| US4249006A (en) | 1981-02-03 |
| PL104613B1 (pl) | 1979-08-31 |
| FR2332991A1 (fr) | 1977-06-24 |
| DK140635B (da) | 1979-10-15 |
| DK528576A (de) | 1977-05-29 |
| NO144887B (no) | 1981-08-24 |
| PT65883B (en) | 1978-10-12 |
| AU1965576A (en) | 1978-05-25 |
| NO764048L (de) | 1977-06-01 |
| MX3873E (es) | 1981-08-26 |
| NL7613285A (nl) | 1977-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |