JPS539778A - Preparation of 5-fluorouracil derivativds - Google Patents

Preparation of 5-fluorouracil derivativds

Info

Publication number
JPS539778A
JPS539778A JP8386376A JP8386376A JPS539778A JP S539778 A JPS539778 A JP S539778A JP 8386376 A JP8386376 A JP 8386376A JP 8386376 A JP8386376 A JP 8386376A JP S539778 A JPS539778 A JP S539778A
Authority
JP
Japan
Prior art keywords
fluorouracil
derivativds
preparation
anticarcinogen
solvolysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8386376A
Other languages
Japanese (ja)
Inventor
Isao Minami
Yoshio Yoshioka
Masaaki Nomura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP8386376A priority Critical patent/JPS539778A/en
Priority to IE2461/76A priority patent/IE45046B1/en
Priority to GR52112A priority patent/GR62855B/en
Priority to CA265,062A priority patent/CA1122983A/en
Priority to CH1402276A priority patent/CH616936A5/fr
Priority to GB47197/76A priority patent/GB1570219A/en
Priority to FR7634249A priority patent/FR2332991A1/en
Priority to AU19655/76A priority patent/AU501833B2/en
Priority to BE6045773A priority patent/BE848662A/en
Priority to MX765150U priority patent/MX3873E/en
Priority to PL1976193890A priority patent/PL104613B1/en
Priority to US05/744,929 priority patent/US4249006A/en
Priority to DK528576AA priority patent/DK140635B/en
Priority to DE2653398A priority patent/DE2653398C2/en
Priority to PT65883A priority patent/PT65883B/en
Priority to AT874876A priority patent/AT346858B/en
Priority to SE7613305A priority patent/SE423389B/en
Priority to NO764048A priority patent/NO144887C/en
Priority to HU76TA1418A priority patent/HU176890B/en
Priority to PH19171A priority patent/PH12998A/en
Priority to NL7613285A priority patent/NL7613285A/en
Publication of JPS539778A publication Critical patent/JPS539778A/en
Priority to SG7/83A priority patent/SG783G/en
Priority to HK112/83A priority patent/HK11283A/en
Priority to MY88/84A priority patent/MY8400088A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)

Abstract

PURPOSE: To prepare the title compounds, useful as anticarcinogen, in high yield with simple operation by the reaction of 5-fluorouracil with 2,3-dihydrofuran, followed by the solvolysis of the formed 1,3-bis compound.
COPYRIGHT: (C)1978,JPO&Japio
JP8386376A 1975-11-28 1976-07-13 Preparation of 5-fluorouracil derivativds Pending JPS539778A (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
JP8386376A JPS539778A (en) 1976-07-13 1976-07-13 Preparation of 5-fluorouracil derivativds
IE2461/76A IE45046B1 (en) 1975-11-28 1976-11-04 Method of producing 5-fluorouracil derivatives
GR52112A GR62855B (en) 1975-11-28 1976-11-05 Preparation process of 5-fluorouracil derivatives
CA265,062A CA1122983A (en) 1975-11-28 1976-11-05 Method of producing 5-fluorouracil derivatives
CH1402276A CH616936A5 (en) 1975-11-28 1976-11-08
GB47197/76A GB1570219A (en) 1975-11-28 1976-11-12 Method of producing 5-fluorouracil derivatives
FR7634249A FR2332991A1 (en) 1975-11-28 1976-11-15 PROCESS FOR THE PRODUCTION OF 5-FLUOROURACYL DERIVATIVES
AU19655/76A AU501833B2 (en) 1975-11-28 1976-11-15 Method of producing 5 -fluorouracii derivatives
BE6045773A BE848662A (en) 1975-11-28 1976-11-23 PROCESS FOR THE PRODUCTION OF 5-FLUOROURACYL DERIVATIVES,
US05/744,929 US4249006A (en) 1975-11-28 1976-11-24 Method of producing 5-fluorouracil derivatives
PL1976193890A PL104613B1 (en) 1975-11-28 1976-11-24 METHOD OF MAKING 1-OR / 1,3-BIS / - / TETRAHYDROGEN-2-FURYL / -5-FLUOROURACYL
MX765150U MX3873E (en) 1975-11-28 1976-11-24 METHOD FOR PRODUCING 5-FLUORURACIL DERIVATIVES
DK528576AA DK140635B (en) 1975-11-28 1976-11-24 Process for the preparation of 1- (tetrahydro-2-furyl) -5-fluorouracil, 1,3-bis- (tetrahydro) -2-furyl) -5-fluorouracil or a mixture thereof.
DE2653398A DE2653398C2 (en) 1975-11-28 1976-11-24 Process for the preparation of 1- (tetrahydro-2-furyl) -5-fluorouracil
PT65883A PT65883B (en) 1975-11-28 1976-11-24 Method of producing 5-fluouracil derivatives
AT874876A AT346858B (en) 1975-11-28 1976-11-25 PROCESS FOR THE PREPARATION OF 1- (TETRAHYDRO-2-FURYL) -5-FLUORURACIL AND / OR 1,3-BIS (TETRAHYDRO-2-FURYL) -5-FLUORURACIL
HU76TA1418A HU176890B (en) 1975-11-28 1976-11-26 Process for preparing 1-/tetrahydro-2furyl/-5-fluoro-uracyl,1,3bis-/tetrahydro-2-furyl/-5-fluoro-uracyl or the mixture of these ywo compounds
NO764048A NO144887C (en) 1975-11-28 1976-11-26 PROCEDURE FOR THE PREPARATION OF 1- (TETRAHYDRO-2-FURYL) -5-FLUORURACIL, OF 1,3-BIS- (TETRAHYDRO-2-FURYL) -5-FLUORO-URACIL OR OF A MIXTURE OF THESE
SE7613305A SE423389B (en) 1975-11-28 1976-11-26 PROCEDURE FOR PREPARING 5-FLOURURACIL DERIVATIVES
PH19171A PH12998A (en) 1975-11-28 1976-11-26 Method of producing 5-fluorouracil derivatives
NL7613285A NL7613285A (en) 1975-11-28 1976-11-29 PROCESS FOR PREPARING 5-FLUORURACIL COMPOUNDS.
SG7/83A SG783G (en) 1975-11-28 1983-01-10 Method of producing 5-fluorouracil derivatives
HK112/83A HK11283A (en) 1975-11-28 1983-03-24 Method of producing 5-fluorouracill derivatives
MY88/84A MY8400088A (en) 1975-11-28 1984-12-30 Method of producing 5-fluorouracil derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8386376A JPS539778A (en) 1976-07-13 1976-07-13 Preparation of 5-fluorouracil derivativds

Publications (1)

Publication Number Publication Date
JPS539778A true JPS539778A (en) 1978-01-28

Family

ID=13814504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8386376A Pending JPS539778A (en) 1975-11-28 1976-07-13 Preparation of 5-fluorouracil derivativds

Country Status (1)

Country Link
JP (1) JPS539778A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61174282A (en) * 1985-01-29 1986-08-05 Idemitsu Petrochem Co Ltd Adhesive for anticorrosive tape

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61174282A (en) * 1985-01-29 1986-08-05 Idemitsu Petrochem Co Ltd Adhesive for anticorrosive tape
JPH0361713B2 (en) * 1985-01-29 1991-09-20 Idemitsu Petrochemical Co

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