JPS52156878A - Preparation of 1-(2-tetrahydrofuryl-uracils) - Google Patents
Preparation of 1-(2-tetrahydrofuryl-uracils)Info
- Publication number
- JPS52156878A JPS52156878A JP7332976A JP7332976A JPS52156878A JP S52156878 A JPS52156878 A JP S52156878A JP 7332976 A JP7332976 A JP 7332976A JP 7332976 A JP7332976 A JP 7332976A JP S52156878 A JPS52156878 A JP S52156878A
- Authority
- JP
- Japan
- Prior art keywords
- uracils
- tetrahydrofuryl
- preparation
- anticarcinogens
- dihydrofuran
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- JKTCBAGSMQIFNL-UHFFFAOYSA-N 2,3-dihydrofuran Chemical compound C1CC=CO1 JKTCBAGSMQIFNL-UHFFFAOYSA-N 0.000 abstract 1
- 239000003005 anticarcinogenic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Formation Of Insulating Films (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To easily prepare the title compounds; useful as pharmaceuticals, especially, low toxic anticarcinogens; with one-stage process by the reaction of uracils with 2,3-dihydrofuran.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7332976A JPS52156878A (en) | 1976-06-23 | 1976-06-23 | Preparation of 1-(2-tetrahydrofuryl-uracils) |
DE19772709839 DE2709839A1 (en) | 1976-06-23 | 1977-03-07 | PROCESS FOR THE PREPARATION OF 5-FLUORURACIL DERIVATIVES |
FR7706751A FR2355841A1 (en) | 1976-06-23 | 1977-03-08 | (N)-(2)-Tetrahydrofuryl-(5)-fluoro-uracil prepn. - by reaction of (5)-fluorouracil and excess (2,3)-dihydrofuran in a polar aprotic solvent (NL 28.12.77) |
FI770741A FI770741A (en) | 1976-06-23 | 1977-03-08 | |
NL7702516A NL7702516A (en) | 1976-06-23 | 1977-03-09 | PROCEDURE FOR PREPARING A 5-FLUORURACIL DERIVATIVE. |
NO770855A NO770855L (en) | 1976-06-23 | 1977-03-10 | PROCEDURES FOR THE PREPARATION OF 5-FLUORURACIL DERIVATIVES |
DK107777A DK107777A (en) | 1976-06-23 | 1977-03-11 | PROCEDURE FOR PREPARING A 5-FLUORURACILE DERIVATIVE |
SE7702797A SE7702797L (en) | 1976-06-23 | 1977-03-11 | PROCEDURE FOR PREPARING 5-FLUOROURACIL DERIVATIVES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7332976A JPS52156878A (en) | 1976-06-23 | 1976-06-23 | Preparation of 1-(2-tetrahydrofuryl-uracils) |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS52156878A true JPS52156878A (en) | 1977-12-27 |
Family
ID=13515008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7332976A Pending JPS52156878A (en) | 1976-06-23 | 1976-06-23 | Preparation of 1-(2-tetrahydrofuryl-uracils) |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS52156878A (en) |
DE (1) | DE2709839A1 (en) |
DK (1) | DK107777A (en) |
FI (1) | FI770741A (en) |
FR (1) | FR2355841A1 (en) |
NL (1) | NL7702516A (en) |
NO (1) | NO770855L (en) |
SE (1) | SE7702797L (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5268188A (en) * | 1975-11-28 | 1977-06-06 | Takeda Chem Ind Ltd | Preparation of 1-(tetrahydro-2-furyl)-5-fluorouracil |
-
1976
- 1976-06-23 JP JP7332976A patent/JPS52156878A/en active Pending
-
1977
- 1977-03-07 DE DE19772709839 patent/DE2709839A1/en active Pending
- 1977-03-08 FR FR7706751A patent/FR2355841A1/en not_active Withdrawn
- 1977-03-08 FI FI770741A patent/FI770741A/fi not_active Application Discontinuation
- 1977-03-09 NL NL7702516A patent/NL7702516A/en not_active Application Discontinuation
- 1977-03-10 NO NO770855A patent/NO770855L/en unknown
- 1977-03-11 DK DK107777A patent/DK107777A/en unknown
- 1977-03-11 SE SE7702797A patent/SE7702797L/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5268188A (en) * | 1975-11-28 | 1977-06-06 | Takeda Chem Ind Ltd | Preparation of 1-(tetrahydro-2-furyl)-5-fluorouracil |
Also Published As
Publication number | Publication date |
---|---|
FI770741A (en) | 1977-12-24 |
DK107777A (en) | 1977-12-24 |
FR2355841A1 (en) | 1978-01-20 |
NO770855L (en) | 1977-12-27 |
SE7702797L (en) | 1977-12-24 |
DE2709839A1 (en) | 1977-12-29 |
NL7702516A (en) | 1977-12-28 |
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