US3922373A
(en)
*
|
1973-03-26 |
1975-11-25 |
Capsulated Systems Inc |
Solid microglobules containing dispersed materials
|
GB1413186A
(en)
*
|
1973-06-27 |
1975-11-12 |
Toyo Jozo Kk |
Process for encapsulation of medicaments
|
JPS5840529B2
(ja)
*
|
1975-09-29 |
1983-09-06 |
明治製菓株式会社 |
ケイコウヨウセイザイノセイホウ
|
DE2812307A1
(de)
*
|
1978-03-21 |
1979-10-04 |
Basf Ag |
Zubereitungen von dispersionsfarbstoffen
|
IT1148784B
(it)
*
|
1980-04-09 |
1986-12-03 |
Eurand Spa |
Procedimento per la preparazione di microcapsule in un veicolo liquido
|
US4507276A
(en)
*
|
1982-08-20 |
1985-03-26 |
Bristol-Myers Company |
Analgesic capsule
|
HU187215B
(en)
*
|
1983-01-26 |
1985-11-28 |
Egyt Gyogyszervegyeszeti Gyar |
Method for producing pharmaceutical product of high actor content and prolonged effect
|
US4670250A
(en)
*
|
1983-10-21 |
1987-06-02 |
Bend Research, Inc. |
Durable controlled release microcapsules
|
US4492720A
(en)
*
|
1983-11-15 |
1985-01-08 |
Benjamin Mosier |
Method of preparing microspheres for intravascular delivery
|
IE58110B1
(en)
*
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
US5840293A
(en)
*
|
1988-11-16 |
1998-11-24 |
Advanced Polymer Systems, Inc. |
Ionic beads for controlled release and adsorption
|
US5484584A
(en)
*
|
1990-10-02 |
1996-01-16 |
Board Of Regents, The University Of Texas System |
Therapeutic and diagnostic use of modified polymeric microcapsules
|
US5238714A
(en)
*
|
1990-10-02 |
1993-08-24 |
Board Of Regents, The University Of Texas System |
Efficient microcapsule preparation and method of use
|
CH683149A5
(fr)
*
|
1991-07-22 |
1994-01-31 |
Debio Rech Pharma Sa |
Procédé pour la préparation de microsphères en matériau polymère biodégradable.
|
US5912015A
(en)
*
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
CA2129514A1
(fr)
*
|
1992-03-12 |
1993-09-16 |
M. Amin Khan |
Acth a liberation controlee, contenant des microspheres
|
US6514533B1
(en)
|
1992-06-11 |
2003-02-04 |
Alkermas Controlled Therapeutics, Inc. |
Device for the sustained release of aggregation-stabilized, biologically active agent
|
FR2693905B1
(fr)
*
|
1992-07-27 |
1994-09-02 |
Rhone Merieux |
Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
|
ATE161716T1
(de)
*
|
1992-08-07 |
1998-01-15 |
Takeda Chemical Industries Ltd |
Herstellung von mikrokapseln, die wasserlösliche arzneimittel enthalten
|
US6375872B1
(en)
|
1992-11-17 |
2002-04-23 |
Moore Business Forms |
Microencapsulated adhesive
|
US5278194A
(en)
*
|
1993-03-25 |
1994-01-11 |
Microsome |
Environmentall dispersible syntactic foam
|
NZ276088A
(en)
|
1993-11-19 |
1999-07-29 |
Janssen Pharmaceutica Nv |
[(1,2-benzisoxazol-3-yl)-1-piperidinyl-alkyl-6,7,8,9-tetrahydro-4h- pyrido[1,2-a]-pyrimidin-4-one derivatives (ie risperidone)
|
US5650173A
(en)
*
|
1993-11-19 |
1997-07-22 |
Alkermes Controlled Therapeutics Inc. Ii |
Preparation of biodegradable microparticles containing a biologically active agent
|
EP1649850A1
(fr)
*
|
1993-11-19 |
2006-04-26 |
Alkermes Controlled Therapeutics Inc. II |
Préparation des microparticules biodégradables contenant un agent biologiquement actif
|
US5599583A
(en)
*
|
1994-05-27 |
1997-02-04 |
Micro Flo Company |
Encapsulation with water soluble polymer
|
US6281015B1
(en)
|
1994-12-16 |
2001-08-28 |
Children's Medical Center Corp. |
Localized delivery of factors enhancing survival of transplanted cells
|
US5922253A
(en)
*
|
1995-05-18 |
1999-07-13 |
Alkermes Controlled Therapeutics, Inc. |
Production scale method of forming microparticles
|
CA2230494A1
(fr)
*
|
1995-08-31 |
1997-03-06 |
Alkermes Controlled Therapeutics Inc. |
Composition se pretant a la liberation prolongee d'un agent
|
DE19545257A1
(de)
|
1995-11-24 |
1997-06-19 |
Schering Ag |
Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
|
US5792477A
(en)
|
1996-05-07 |
1998-08-11 |
Alkermes Controlled Therapeutics, Inc. Ii |
Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent
|
US5945126A
(en)
*
|
1997-02-13 |
1999-08-31 |
Oakwood Laboratories L.L.C. |
Continuous microsphere process
|
US5989463A
(en)
*
|
1997-09-24 |
1999-11-23 |
Alkermes Controlled Therapeutics, Inc. |
Methods for fabricating polymer-based controlled release devices
|
US6824793B1
(en)
*
|
1998-06-01 |
2004-11-30 |
Chiron Corporation |
Use of hyaluronic acid polymers for mucosal delivery of vaccine antigens and adjuvants
|
US6270802B1
(en)
|
1998-10-28 |
2001-08-07 |
Oakwood Laboratories L.L.C. |
Method and apparatus for formulating microspheres and microcapsules
|
US6194006B1
(en)
|
1998-12-30 |
2001-02-27 |
Alkermes Controlled Therapeutics Inc. Ii |
Preparation of microparticles having a selected release profile
|
JP2002537355A
(ja)
|
1999-02-26 |
2002-11-05 |
カイロン コーポレイション |
抗原の粘膜送達のための生体接着剤およびアジュバントの使用
|
US6204308B1
(en)
|
1999-03-01 |
2001-03-20 |
Novartis Ag |
Organic compounds
|
US6291013B1
(en)
|
1999-05-03 |
2001-09-18 |
Southern Biosystems, Inc. |
Emulsion-based processes for making microparticles
|
WO2001006054A1
(fr)
|
1999-07-19 |
2001-01-25 |
Avantgarb, Llc |
Traitement permanent de textiles à base de nanoparticules
|
US6458387B1
(en)
*
|
1999-10-18 |
2002-10-01 |
Epic Therapeutics, Inc. |
Sustained release microspheres
|
US6495166B1
(en)
|
1999-11-12 |
2002-12-17 |
Alkermes Controlled Therapeutics Inc. |
Apparatus and method for preparing microparticles using in-line solvent extraction
|
US6331317B1
(en)
*
|
1999-11-12 |
2001-12-18 |
Alkermes Controlled Therapeutics Ii Inc. |
Apparatus and method for preparing microparticles
|
US6705757B2
(en)
*
|
1999-11-12 |
2004-03-16 |
Alkermes Controlled Therapeutics, Inc. Ii |
Method and apparatus for preparing microparticles using in-line solvent extraction
|
US7838037B2
(en)
|
1999-11-17 |
2010-11-23 |
Tagra Biotechnologies Ltd. |
Method of microencapsulation
|
GB2356386A
(en)
|
1999-11-17 |
2001-05-23 |
Tagra Biotechnologies Ltd |
Microencapsulation
|
WO2001068080A2
(fr)
|
2000-03-15 |
2001-09-20 |
Wolfgang Sadee |
Antagonistes neutres et utilisation de ces derniers dans le traitement de l'abus des drogues
|
US6264987B1
(en)
*
|
2000-05-19 |
2001-07-24 |
Alkermes Controlled Therapeutics Inc. Ii |
Method for preparing microparticles having a selected polymer molecular weight
|
US6495164B1
(en)
*
|
2000-05-25 |
2002-12-17 |
Alkermes Controlled Therapeutics, Inc. I |
Preparation of injectable suspensions having improved injectability
|
US6719970B1
(en)
|
2000-07-10 |
2004-04-13 |
Alkermes Controlled Therapeutics, Inc. |
Method of generating cartilage
|
US6824822B2
(en)
*
|
2001-08-31 |
2004-11-30 |
Alkermes Controlled Therapeutics Inc. Ii |
Residual solvent extraction method and microparticles produced thereby
|
US6471995B1
(en)
|
2000-09-27 |
2002-10-29 |
Alkermes Controlled Therapeutics, Inc. Ii |
Apparatus and method for preparing microparticles using liquid-liquid extraction
|
EP1335661B1
(fr)
|
2000-10-27 |
2009-05-06 |
Baxter Healthcare S.A. |
Production de microspheres
|
AU2002235253A1
(en)
|
2000-12-21 |
2002-07-01 |
Inhale Therapeutic Systems, Inc. |
Induced phase transition method for the production of microparticles containing hydrophilic active agents
|
US20020114843A1
(en)
*
|
2000-12-27 |
2002-08-22 |
Ramstack J. Michael |
Preparation of microparticles having improved flowability
|
US20060269602A1
(en)
*
|
2001-04-13 |
2006-11-30 |
Dasch James R |
Method of modifying the release profile of sustained release compositions
|
US6558702B2
(en)
*
|
2001-04-13 |
2003-05-06 |
Alkermes Controlled Therapeutics, Inc. |
Method of modifying the release profile of sustained release compositions
|
US20080026068A1
(en)
*
|
2001-08-16 |
2008-01-31 |
Baxter Healthcare S.A. |
Pulmonary delivery of spherical insulin microparticles
|
EP1418890B1
(fr)
*
|
2001-08-16 |
2008-05-14 |
Baxter International Inc. |
Preparations de microparticules a base d'un agent propulseur
|
JP2005517012A
(ja)
*
|
2002-02-08 |
2005-06-09 |
アルカーメス コントロールド セラピューティクス,インコーポレイテッド |
持続放出のためのポリマーベース組成物
|
US7157102B1
(en)
|
2002-05-31 |
2007-01-02 |
Biotek, Inc. |
Multi-layered microcapsules and method of preparing same
|
US7041320B1
(en)
|
2002-05-31 |
2006-05-09 |
Biotek, Inc. |
High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence
|
US7164005B2
(en)
*
|
2002-10-17 |
2007-01-16 |
Alkermes, Inc. |
Microencapsulation and sustained release of biologically active polypeptides
|
US20040131662A1
(en)
|
2003-11-12 |
2004-07-08 |
Davidson Robert S. |
Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
|
US20040191302A1
(en)
|
2003-03-28 |
2004-09-30 |
Davidson Robert S. |
Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
|
US8999372B2
(en)
*
|
2002-11-14 |
2015-04-07 |
Cure Pharmaceutical Corporation |
Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
|
US9561182B2
(en)
*
|
2003-08-22 |
2017-02-07 |
Cure Pharmaceutical Corporation |
Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
|
US7691296B2
(en)
*
|
2002-11-25 |
2010-04-06 |
Amorepacific Corporation |
Method for stabilizing active components using polyol/polymer microcapsule, and cosmetic composition containing the microcapsule
|
US20070207211A1
(en)
*
|
2003-04-10 |
2007-09-06 |
Pr Pharmaceuticals, Inc. |
Emulsion-based microparticles and methods for the production thereof
|
CA2516107C
(fr)
|
2003-04-10 |
2013-12-24 |
Ehud Zeigerson |
Procede de production de microparticules a base d'emulsion
|
US7101617B2
(en)
*
|
2003-07-10 |
2006-09-05 |
Motorola, Inc. |
Silicone dispensing with a conformal film
|
JP5165239B2
(ja)
*
|
2003-07-15 |
2013-03-21 |
ピーアール ファーマシューティカルズ, インコーポレイテッド |
制御放出処方物の調製のための方法
|
US20070092452A1
(en)
*
|
2003-07-18 |
2007-04-26 |
Julia Rashba-Step |
Methods for fabrication, uses, compositions of inhalable spherical particles
|
KR101137785B1
(ko)
*
|
2003-07-18 |
2012-04-25 |
백스터 인터내셔널 인코포레이티드 |
제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
|
US20050142205A1
(en)
*
|
2003-07-18 |
2005-06-30 |
Julia Rashba-Step |
Methods for encapsulating small spherical particles prepared by controlled phase separation
|
EP1646354A4
(fr)
*
|
2003-07-22 |
2010-03-17 |
Baxter Int |
Petites particules spheriques de molecules organiques de faible poids moleculaire et procedes de preparation et d'utilisation correspondants
|
WO2005009357A2
(fr)
*
|
2003-07-23 |
2005-02-03 |
Pr Pharmaceuticals, Inc. |
Compositions a liberation controlee
|
US7456254B2
(en)
*
|
2004-04-15 |
2008-11-25 |
Alkermes, Inc. |
Polymer-based sustained release device
|
MXPA06011924A
(es)
*
|
2004-04-15 |
2007-06-11 |
Alkermes Inc |
Dispositivo de liberacion continua base polimeros.
|
US20060110423A1
(en)
*
|
2004-04-15 |
2006-05-25 |
Wright Steven G |
Polymer-based sustained release device
|
US20050238618A1
(en)
*
|
2004-04-23 |
2005-10-27 |
Yujin Huang |
Low molecular weight polymers
|
US20050260272A1
(en)
*
|
2004-05-05 |
2005-11-24 |
Alkermes Controlled Therapeutics, Inc. |
Method of forming microparticles that include a bisphosphonate and a polymer
|
JP2007537288A
(ja)
*
|
2004-05-12 |
2007-12-20 |
バクスター インターナショナル インコーポレイテッド |
オリゴヌクレオチド含有マイクロスフェア、1型糖尿病を処置する医薬の製造のための、その使用
|
CN103393601A
(zh)
*
|
2004-05-12 |
2013-11-20 |
巴克斯特国际公司 |
含有蛋白并在高浓度蛋白下显示可注射性的微球体
|
DK1765294T3
(da)
|
2004-05-12 |
2008-11-10 |
Baxter Int |
Nukleinsyremikrokugler samt deres fremstilling og afgivelse
|
US8728525B2
(en)
*
|
2004-05-12 |
2014-05-20 |
Baxter International Inc. |
Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
|
US7740861B2
(en)
*
|
2004-06-16 |
2010-06-22 |
University Of Massachusetts |
Drug delivery product and methods
|
ATE536175T1
(de)
*
|
2004-09-17 |
2011-12-15 |
Univ Massachusetts |
Zusammensetzungen und ihre verwendungen bei lysosomalen enzymstörungen
|
WO2006078841A1
(fr)
*
|
2005-01-21 |
2006-07-27 |
President And Fellows Of Harvard College |
Systemes et procedes de formation de gouttelettes fluidiques encapsulees dans des particules telles que des particules colloidales
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
CN101188996B
(zh)
*
|
2005-04-27 |
2013-03-27 |
巴克斯特国际公司 |
表面改性的微粒及其形成和使用方法
|
AU2006306228A1
(en)
*
|
2005-10-24 |
2007-05-03 |
University Of Massachusetts |
Compositions and their uses for gene therapy of bone conditions
|
US20070281031A1
(en)
*
|
2006-06-01 |
2007-12-06 |
Guohan Yang |
Microparticles and methods for production thereof
|
JP5118139B2
(ja)
*
|
2006-08-04 |
2013-01-16 |
バクスター・インターナショナル・インコーポレイテッド |
新規発症自己免疫性糖尿病を予防および/または逆転させるためのマイクロスフィアに基づく組成物
|
PL2359808T3
(pl)
|
2006-08-09 |
2013-10-31 |
Intarcia Therapeutics Inc |
Osmotyczne systemy dostawcze i zespoły tłokowe
|
CN101511347B
(zh)
*
|
2006-08-31 |
2012-11-28 |
Sk化学株式会社 |
含药物微球的制造方法及由该方法制造的含药物微球
|
US20080248122A1
(en)
*
|
2006-10-06 |
2008-10-09 |
Baxter International Inc. |
Microencapsules Containing Surface-Modified Microparticles And Methods Of Forming And Using The Same
|
JP2010522196A
(ja)
*
|
2007-03-22 |
2010-07-01 |
アルカームズ,インコーポレイテッド |
コアセルベーション工程
|
CA2683610C
(fr)
|
2007-04-23 |
2013-01-08 |
Intarcia Therapeutics, Inc. |
Formulations en suspension de peptides insulinotropes et leurs utilisations
|
US20080317865A1
(en)
*
|
2007-06-20 |
2008-12-25 |
Alkermes, Inc. |
Quench liquids and washing systems for production of microparticles
|
JP2011500686A
(ja)
*
|
2007-10-18 |
2011-01-06 |
アイコ バイオテクノロジー |
オピオイドと中性アンタゴニストを用いる組合せ鎮痛剤
|
US8748448B2
(en)
|
2007-10-18 |
2014-06-10 |
Aiko Biotechnology |
Combination analgesic employing opioid agonist and neutral antagonist
|
WO2009058913A2
(fr)
*
|
2007-10-29 |
2009-05-07 |
University Of Massachusetts |
Nanoparticules encapsulées pour l'administration d'acides nucléiques
|
DK2240155T3
(da)
|
2008-02-13 |
2012-09-17 |
Intarcia Therapeutics Inc |
Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
|
US8815818B2
(en)
|
2008-07-18 |
2014-08-26 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell delivery of RNAI
|
US8367427B2
(en)
*
|
2008-08-20 |
2013-02-05 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
US20100047292A1
(en)
*
|
2008-08-20 |
2010-02-25 |
Baxter International Inc. |
Methods of processing microparticles and compositions produced thereby
|
US8323685B2
(en)
*
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
US8323615B2
(en)
*
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing multi-phasic dispersions
|
US8664189B2
(en)
|
2008-09-22 |
2014-03-04 |
Rxi Pharmaceuticals Corporation |
RNA interference in skin indications
|
US9493774B2
(en)
|
2009-01-05 |
2016-11-15 |
Rxi Pharmaceuticals Corporation |
Inhibition of PCSK9 through RNAi
|
KR101823699B1
(ko)
|
2009-09-28 |
2018-01-30 |
인타르시아 세라퓨틱스 인코포레이티드 |
실질 항정상태 약물 전달의 신속 확립 및/또는 종결
|
WO2012008834A1
(fr)
|
2010-07-16 |
2012-01-19 |
Delta Crystallon B.V. |
Microparticules comprenant une petite protéine de choc thermique
|
ES2614181T3
(es)
|
2010-08-14 |
2017-05-30 |
University Of Massachusetts |
Partícula de pared celular de levadura para suministro de nanopartículas direccionadas al receptor
|
CA2812063A1
(fr)
|
2010-08-30 |
2012-06-07 |
President And Fellows Of Harvard College |
Liberation controlee par cisaillement pour lesions stenosees et traitements thrombolytiques
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
AU2014324837B2
(en)
|
2013-09-30 |
2019-01-17 |
Zoetis Services Llc |
Long-acting spiro-isoxazoline formulations
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
MX2017015504A
(es)
|
2015-06-03 |
2018-05-15 |
Intarcia Therapeutics Inc |
Sistemas de colocacion y remoción de implante.
|
EP3238816B1
(fr)
*
|
2016-04-29 |
2019-10-09 |
Symrise AG |
Procédé pour la preparation de microcapsules
|
AU2017268161B2
(en)
|
2016-05-16 |
2020-03-12 |
Intarcia Therapeutics, Inc. |
Glucagon-receptor selective polypeptides and methods of use thereof
|
WO2017199123A1
(fr)
|
2016-05-17 |
2017-11-23 |
Ecole Polytechnique Federale De Lausanne (Epfl) |
Dispositif et procédés d'élimination de phase d'enveloppe de capsules de type noyau-enveloppe
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
AU2018206539A1
(en)
|
2017-01-03 |
2019-07-18 |
Intarcia Therapeutics, Inc. |
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|
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华东理工大学 |
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