DK1397095T3 - Misbrugsresistente, opioid-holdige transdermale systemer - Google Patents

Misbrugsresistente, opioid-holdige transdermale systemer

Info

Publication number
DK1397095T3
DK1397095T3 DK02731653T DK02731653T DK1397095T3 DK 1397095 T3 DK1397095 T3 DK 1397095T3 DK 02731653 T DK02731653 T DK 02731653T DK 02731653 T DK02731653 T DK 02731653T DK 1397095 T3 DK1397095 T3 DK 1397095T3
Authority
DK
Denmark
Prior art keywords
opioid
abuse
resistant
transdermal systems
dosage form
Prior art date
Application number
DK02731653T
Other languages
Danish (da)
English (en)
Inventor
Mark A Alfonso
Anthony E Carpanzano
Rampurna Prasad Gullapalli
Richard S Sackler
Benjamin Oshlack
Lino Tavares
Curtis Wright
James P Cassidy
Ihor Shevchuk
Bruce E Reidenberg
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of DK1397095T3 publication Critical patent/DK1397095T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B3/00—Destroying solid waste or transforming solid waste into something useful or harmless
    • B09B3/0075—Disposal of medical waste
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B2101/00—Type of solid waste
    • B09B2101/65—Medical waste
    • B09B2101/68—Transdermal patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02731653T 2001-05-01 2002-04-30 Misbrugsresistente, opioid-holdige transdermale systemer DK1397095T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28787501P 2001-05-01 2001-05-01
US29253701P 2001-05-22 2001-05-22
PCT/US2002/014073 WO2002087482A1 (en) 2001-05-01 2002-04-30 Abuse resistant opioid containing transdermal systems

Publications (1)

Publication Number Publication Date
DK1397095T3 true DK1397095T3 (da) 2009-03-09

Family

ID=26964697

Family Applications (3)

Application Number Title Priority Date Filing Date
DK02731653T DK1397095T3 (da) 2001-05-01 2002-04-30 Misbrugsresistente, opioid-holdige transdermale systemer
DK08020810.1T DK2062573T3 (da) 2001-05-01 2002-04-30 Misbrugsresistent opioid indeholdende transdermale systemer
DK10009943.1T DK2316439T3 (en) 2001-05-01 2002-04-30 Abuse-proof transdermal systems containing opioids

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK08020810.1T DK2062573T3 (da) 2001-05-01 2002-04-30 Misbrugsresistent opioid indeholdende transdermale systemer
DK10009943.1T DK2316439T3 (en) 2001-05-01 2002-04-30 Abuse-proof transdermal systems containing opioids

Country Status (11)

Country Link
US (2) US20040241218A1 (de)
EP (3) EP1397095B1 (de)
JP (3) JP5296284B2 (de)
AT (2) ATE415952T1 (de)
CY (2) CY1108821T1 (de)
DE (1) DE60230138D1 (de)
DK (3) DK1397095T3 (de)
ES (3) ES2377672T3 (de)
PT (3) PT2316439E (de)
SI (3) SI2316439T1 (de)
WO (1) WO2002087482A1 (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
WO2002094172A2 (en) 2001-05-22 2002-11-28 Euro-Celtique Compartmentalized dosage form
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
AR039336A1 (es) * 2002-04-23 2005-02-16 Alza Corp Sistemas analgesicos transdermicos con potencial de abuso reducido
SI1513532T1 (sl) * 2002-06-10 2007-08-31 Euro Celtique Sa Sistemi za odstranjevanje priprav za transdermalno oddajanje za preprečevanje zlorabe učinkovin, ki jih vsebujejo
EP2422775A3 (de) * 2002-09-20 2012-04-18 Alpharma, Inc. Sequestriermitteluntereinheit und zugehörige Zusammensetzungen und Verfahren
DE10250088A1 (de) * 2002-10-25 2004-05-06 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
KR101159828B1 (ko) * 2003-04-30 2012-07-04 퍼듀 퍼머 엘피 활성제 구성요소 및 활성제 층의 원위부에 억제제 구성요소를 포함하는 내변조성 경피제형
US20040219195A1 (en) * 2003-04-30 2004-11-04 3M Innovative Properties Company Abuse-resistant transdermal dosage form
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US7182955B2 (en) 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
CA2529983C (en) * 2003-07-25 2010-07-20 Bruce E. Reidenberg Preoperative treatment of post operative pain
KR20060120678A (ko) * 2003-10-30 2006-11-27 알자 코포레이션 남용될 가능성이 감소된 경피용 진통제 시스템
US8535711B2 (en) * 2004-01-23 2013-09-17 Teikoku Pharma Usa, Inc. Medication disposal system
US7867511B2 (en) 2004-01-23 2011-01-11 Travanti Pharma Inc. Abuse potential reduction in abusable substance dosage form
HUE030128T2 (en) * 2004-02-23 2017-04-28 Euro Celtique Sa Anti-abuse device for transdermal opioid administration
US20070269522A1 (en) * 2004-08-20 2007-11-22 Wold Chad R Transdermal Drug Delivery Device with Translucent Protective Film
US7226619B1 (en) 2004-09-07 2007-06-05 Pharmorx Inc. Material for controlling diversion of medications
JP5254616B2 (ja) 2004-09-13 2013-08-07 クロノ セラピューティクス、インコーポレイテッド 生物学的同調性（ｂｉｏｓｙｎｃｈｒｏｎｏｕｓ）経皮的薬物送達
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
EP2216018B1 (de) * 2004-10-21 2012-04-04 Durect Corporation Transdermale Abgabesysteme
WO2006069008A1 (en) * 2004-12-22 2006-06-29 Vesta Medical, Llc Compositions and devices for inactivation of pharmaceuticals to facilitate waste disposal, and methods thereof
US20060182819A1 (en) * 2005-02-17 2006-08-17 Ough Yon D Soap scent patch and treatment for muscle spasm and pain
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
WO2006124749A2 (en) * 2005-05-13 2006-11-23 Alza Corporation Multilayer drug delivery system with barrier against antagonist exposure
WO2006124585A2 (en) 2005-05-13 2006-11-23 Alza Corporation Multilayer drug system for the delivery of galantamine
US20070014839A1 (en) * 2005-07-18 2007-01-18 Stefan Bracht Decomposer film for transdermal patches
US9056061B2 (en) 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
EP2308480B1 (de) 2005-09-23 2014-08-13 ALZA Corporation Polyacrylatformulierung mit hoher Beladung von verstärkenden Substanzen für transdermale Anwendungen
WO2007070632A2 (en) * 2005-12-13 2007-06-21 Biodelivery Sciences International, Inc. Abuse resistant transmucosal drug delivery device
DE102006025282A1 (de) * 2006-05-31 2007-12-20 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System
SI2484346T1 (sl) 2006-06-19 2017-05-31 Alpharma Pharmaceuticals Llc Farmacevtski sestavki
US20080008747A1 (en) * 2006-07-07 2008-01-10 Royds Robert B Transdermal patch
AU2007275581B2 (en) 2006-07-21 2011-09-08 Biodelivery Sciences International, Inc. Transmucosal delivery devices with enhanced uptake
US20080233156A1 (en) * 2006-10-11 2008-09-25 Alpharma, Inc. Pharmaceutical compositions
US20080286348A1 (en) * 2007-05-16 2008-11-20 Todhunter John A Secured transdermal delivery system
DE102007041557B4 (de) * 2007-08-29 2011-03-31 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend längliche Hohlkörper
AU2008338442A1 (en) * 2007-12-17 2009-06-25 Alpharma Pharmaceuticals, Llc Pharmaceutical composition
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
MX2010010512A (es) * 2008-03-26 2010-11-09 Alltranz Inc Formulaciones transdermicas de agonistas y antagonistas-agonistas de opiato que impiden el abuso.
DE102008016804B4 (de) 2008-04-02 2012-01-05 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System mit verbesserter Funktionalität und Wirksamkeit sowie seine Verwendung
JP2013523780A (ja) * 2010-04-02 2013-06-17 オールトランツ インコーポレイティド オピエートアゴニスト及びアゴニスト−アンタゴニストの乱用抑止性経皮製剤
CA2841785A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
BR112014003651B1 (pt) 2011-08-18 2022-03-29 Biodelivery Sciences International, Inc Dispositivos mucoadesivos resistentes ao mau uso para a liberação de buprenorfina
WO2013049380A1 (en) 2011-09-30 2013-04-04 Teikoku Pharma Usa, Inc. Transdermal patch disposal system
JP2014528276A (ja) 2011-09-30 2014-10-27 テイコク ファーマ ユーエスエー インコーポレーテッド 一般用医薬品廃棄システム
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
WO2016049266A1 (en) * 2014-09-24 2016-03-31 Pain Therapeutics, Inc. 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal
US10010543B1 (en) 2014-12-23 2018-07-03 Barr Laboratories, Inc. Transdermal dosage form
EP3250258A4 (de) 2015-01-28 2018-09-05 Chrono Therapeutics, Inc. Verfahren und systeme zur wirkstofffreisetzung
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
AU2017224129B2 (en) * 2016-02-26 2022-06-30 Case Western Reserve University Composite membranes for flow batteries
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 経皮薬剤送達の装置及び方法
US11389844B2 (en) 2018-03-20 2022-07-19 Verde Environmental Technologies, Inc. Blister pack disposal system
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
WO2020009685A1 (en) * 2018-07-02 2020-01-09 John Tang Transdermal dosage form
WO2020008366A1 (en) * 2018-07-02 2020-01-09 Clexio Biosciences Ltd. Transdermal dosage form
US20210346662A1 (en) * 2018-10-23 2021-11-11 Kindeva Drug Delivery L.P. Tamper evident transdermal patch
US20220313686A1 (en) * 2019-08-12 2022-10-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Pharmaceutical compositions comprising a combination of opioid antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3643987A1 (de) * 1986-12-22 1988-06-23 Lohmann Therapie Syst Lts Basische, wirkstoffdurchlaessige haftklebende polymermasse, insbesondere zum einsatz mit basischen wirkstoffen, verfahren zu ihrer herstellung und ihre verwendung
US5236714A (en) * 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5149538A (en) * 1991-06-14 1992-09-22 Warner-Lambert Company Misuse-resistive transdermal opioid dosage form
US6096756A (en) * 1992-09-21 2000-08-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
US5573778A (en) * 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
WO1997004835A1 (de) * 1995-07-28 1997-02-13 Novartis Ag Transdermales system
US7011843B2 (en) * 1997-10-01 2006-03-14 Lts Lohmann-Therapie Systeme Ag Method for protecting a human being against health impairment by ingestion of a transdermal therapeutic system
KR100417490B1 (ko) 1997-12-22 2004-02-05 유로-셀티크 소시에떼 아노뉨 오피오이드 제형의 남용을 방지하는 방법
US6554851B1 (en) * 1999-05-07 2003-04-29 Scimed Life Systems, Inc. Methods of sealing an injection site
DK1424973T3 (da) * 2001-04-23 2010-06-14 Euro Celtique Sa Bortskaffelsessystem til transdermal doseringsform

Also Published As

Publication number Publication date
EP1397095A4 (de) 2005-05-25
JP2004529155A (ja) 2004-09-24
US20140199383A1 (en) 2014-07-17
ATE533478T1 (de) 2011-12-15
CY1112271T1 (el) 2015-12-09
EP2062573B1 (de) 2011-11-16
CY1108821T1 (el) 2014-04-09
ES2546828T3 (es) 2015-09-29
JP2015042649A (ja) 2015-03-05
DK2316439T3 (en) 2015-08-10
DE60230138D1 (de) 2009-01-15
US20040241218A1 (en) 2004-12-02
SI2316439T1 (sl) 2015-10-30
ATE415952T1 (de) 2008-12-15
JP2013144702A (ja) 2013-07-25
JP5296284B2 (ja) 2013-09-25
EP2316439B1 (de) 2015-06-17
PT1397095E (pt) 2009-02-17
EP1397095B1 (de) 2008-12-03
EP2062573A1 (de) 2009-05-27
PT2316439E (pt) 2015-08-28
PT2062573E (pt) 2012-01-11
EP1397095A1 (de) 2004-03-17
DK2062573T3 (da) 2012-01-30
ES2377672T3 (es) 2012-03-29
SI2062573T1 (sl) 2012-02-29
ES2318010T3 (es) 2009-05-01
EP2316439A1 (de) 2011-05-04
SI1397095T1 (sl) 2009-04-30
WO2002087482A1 (en) 2002-11-07

Similar Documents

Publication Publication Date Title
DK1397095T3 (da) Misbrugsresistente, opioid-holdige transdermale systemer
DE60127277D1 (de) Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert
DE60118885D1 (de) Nitratsalze von antimikrobiellen wirkstoffen
DE60318237D1 (de) Pharmazeutische zusammensetzungen enthaltend flavonoide und menthol
AU2791302A (en) Synergistic medicament containing aromatic agents and having an antagonistic, regenerative and/or protagonist decontamination effect
ATE342097T1 (de) Elektroaktive pore
AU2002227913A1 (en) Synergistic medicament containing aromatic agents and having an antagonistic, regenerative and/or protagonist decontamination effect
BR9917089A (pt) Composições e métodos para distribuição mucosal
BR0313627A (pt) Formulações farmacêuticas, processos para a preparação de formulação farmacêutica e método para o tratamento de dores
MXPA03011825A (es) Combinacion de ingrediente activo para tratar una dependencia de sustancias aditivas o narcoticas utilizando medicamentos.
DE60233891D1 (de) Selektives targeting von apoptotischen zellen
RS50148B (sr) Upotreba docetaksela za lečenje hepatoćelijskog karcinoma
WO2003008637A3 (en) Use of genotyping in the individualization of therapy
SE0103276L (sv) Anordning för administrering av salva till en hudyta
EE200300213A (et) SARP-1 kasutamine sklerodermia raviks ja/või ennetamiseks
EP1620061A4 (de) Antivirale mittel zur behandlung, kontrolle und prävention von infektionen durch coronaviren
PT1200071E (pt) Comprimidos fracamente doseados e processo de preparacao
HUP0204208A2 (hu) Pruritus kezelésére szolgáló külsőleges gyógyszerkészítmény
EP1603595A4 (de) Pharmazeutische zusammensetzung zur behandlung von drogenabhängigkeit
WO2002028399A1 (fr) Inducteurs de l'apoptose, activateurs de cascade de caspase et agents anticancers
DE60034770D1 (de) Stabile fumagillin-formulierung
ATE262898T1 (de) Formulierung mit gesteuerter wirkstoffabgabe enthaltend bupropion-hci als wirkstoff
RU2001100069A (ru) Антгельминтное средство
WO2002002089A3 (de) Anthelminthika zur verhinderung von parasitären infektionen bei mensch und tier iv
WO2002002087A3 (de) Anthelmintika zur verhinderung von parasitären infektionen bei menschen und tieren ii