ATE415952T1 - Vor missbrauch geschützte opioid-haltige transdermale systeme - Google Patents

Vor missbrauch geschützte opioid-haltige transdermale systeme

Info

Publication number
ATE415952T1
ATE415952T1 AT02731653T AT02731653T ATE415952T1 AT E415952 T1 ATE415952 T1 AT E415952T1 AT 02731653 T AT02731653 T AT 02731653T AT 02731653 T AT02731653 T AT 02731653T AT E415952 T1 ATE415952 T1 AT E415952T1
Authority
AT
Austria
Prior art keywords
opioid
abuse
transdermal systems
containing transdermal
dosage form
Prior art date
Application number
AT02731653T
Other languages
English (en)
Inventor
Lino Tavares
Bruce Reidenberg
Richard Sackler
Curtis Wright
Mark A Alfonso
Benjamin Oshlack
James Cassidy
Anthony E Carpanzano
Rampurna Prasad Gullapalli
Ihor Shevchuk
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of ATE415952T1 publication Critical patent/ATE415952T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B09DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09BDISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B2101/00Type of solid waste
    • B09B2101/65Medical waste
    • B09B2101/68Transdermal patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02731653T 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme ATE415952T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28787501P 2001-05-01 2001-05-01
US29253701P 2001-05-22 2001-05-22

Publications (1)

Publication Number Publication Date
ATE415952T1 true ATE415952T1 (de) 2008-12-15

Family

ID=26964697

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02731653T ATE415952T1 (de) 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme
AT08020810T ATE533478T1 (de) 2001-05-01 2002-04-30 Missbrauchssichere opioide mit transdermalen systemen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT08020810T ATE533478T1 (de) 2001-05-01 2002-04-30 Missbrauchssichere opioide mit transdermalen systemen

Country Status (11)

Country Link
US (2) US20040241218A1 (de)
EP (3) EP2062573B1 (de)
JP (3) JP5296284B2 (de)
AT (2) ATE415952T1 (de)
CY (2) CY1108821T1 (de)
DE (1) DE60230138D1 (de)
DK (3) DK2316439T3 (de)
ES (3) ES2546828T3 (de)
PT (3) PT1397095E (de)
SI (3) SI2316439T1 (de)
WO (1) WO2002087482A1 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
AU2002339378A1 (en) 2001-05-22 2002-12-03 Euro-Celtique Compartmentalized dosage form
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
DE60336394D1 (de) * 2002-04-23 2011-04-28 Durect Corp Transdermale analgetische systeme mit reduziertem missbrauchspotential
DE60312160T2 (de) * 2002-06-10 2007-10-31 Euro-Celtique S.A. Entsorgungssysteme für transdermale abgabevorrichtungen zur verhinderung des missbrauchs von darin enthaltenen wirkstoffen
DK1551372T3 (en) * 2002-09-20 2018-07-23 Alpharma Pharmaceuticals Llc SEQUERATION SUBSTANCES AND RELATED COMPOSITIONS AND PROCEDURES
DE10250088A1 (de) * 2002-10-25 2004-05-06 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
US7182955B2 (en) * 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US20040219195A1 (en) * 2003-04-30 2004-11-04 3M Innovative Properties Company Abuse-resistant transdermal dosage form
AR047936A1 (es) * 2003-04-30 2006-03-15 Purdue Pharma Ltd Forma de dosificacion transdermica resistente a la manipulacion
CA2529983C (en) * 2003-07-25 2010-07-20 Euro-Celtique S.A. Preoperative treatment of post operative pain
US20070191815A1 (en) 2004-09-13 2007-08-16 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
EP1677771A2 (de) * 2003-10-30 2006-07-12 Alza Corporation Transdermale analgetische systeme mit reduziertem missbrauchspotential
US7867511B2 (en) 2004-01-23 2011-01-11 Travanti Pharma Inc. Abuse potential reduction in abusable substance dosage form
US8535711B2 (en) * 2004-01-23 2013-09-17 Teikoku Pharma Usa, Inc. Medication disposal system
LT2351555T (lt) * 2004-02-23 2016-12-27 Euro-Celtique S.A. Piktnaudžiavimui atspari priemonė, skirta transderminiam opoido įvedimui
WO2006023644A2 (en) * 2004-08-20 2006-03-02 3M Innovative Properties Company Transdermal drug delivery device with translucent protective film
US7226619B1 (en) 2004-09-07 2007-06-05 Pharmorx Inc. Material for controlling diversion of medications
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
ATE471146T1 (de) * 2004-10-21 2010-07-15 Durect Corp Transdermale verabreichungssysteme
WO2006069008A1 (en) * 2004-12-22 2006-06-29 Vesta Medical, Llc Compositions and devices for inactivation of pharmaceuticals to facilitate waste disposal, and methods thereof
US20060182819A1 (en) 2005-02-17 2006-08-17 Ough Yon D Soap scent patch and treatment for muscle spasm and pain
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
WO2006124584A2 (en) 2005-05-13 2006-11-23 Alza Corporation Multilayer drug delivery system with barrier against reservoir material flow
WO2006124749A2 (en) * 2005-05-13 2006-11-23 Alza Corporation Multilayer drug delivery system with barrier against antagonist exposure
US20070014839A1 (en) * 2005-07-18 2007-01-18 Stefan Bracht Decomposer film for transdermal patches
US20070098772A1 (en) 2005-09-23 2007-05-03 Westcott Tyler D Transdermal norelgestromin delivery system
EP2308480B1 (de) 2005-09-23 2014-08-13 ALZA Corporation Polyacrylatformulierung mit hoher Beladung von verstärkenden Substanzen für transdermale Anwendungen
WO2007070632A2 (en) * 2005-12-13 2007-06-21 Biodelivery Sciences International, Inc. Abuse resistant transmucosal drug delivery device
DE102006025282A1 (de) * 2006-05-31 2007-12-20 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System
KR101486228B1 (ko) 2006-06-19 2015-01-26 알파마 파머슈티컬스 엘엘씨 약제학적 조성물
US20080008747A1 (en) * 2006-07-07 2008-01-10 Royds Robert B Transdermal patch
AU2007275581B2 (en) 2006-07-21 2011-09-08 Biodelivery Sciences International, Inc. Transmucosal delivery devices with enhanced uptake
CA2665726C (en) * 2006-10-11 2016-04-19 Alpharma, Inc. Pharmaceutical compositions
US20080286348A1 (en) * 2007-05-16 2008-11-20 Todhunter John A Secured transdermal delivery system
DE102007041557B4 (de) * 2007-08-29 2011-03-31 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend längliche Hohlkörper
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
US20090196890A1 (en) * 2007-12-17 2009-08-06 Alpharma Pharmaceuticals, Llc Pharmaceutical compositions
EP2254561A2 (de) * 2008-03-26 2010-12-01 AllTranz Inc. Missbrauchssichere transdermale formulierungen von opiat-agonisten und -agonist-antagonisten
DE102008016804B4 (de) 2008-04-02 2012-01-05 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System mit verbesserter Funktionalität und Wirksamkeit sowie seine Verwendung
CA2795158C (en) * 2010-04-02 2019-10-22 Alltranz Inc. Abuse-deterrent transdermal formulations of opiate agonists and agonist-antagonists
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
WO2013026064A1 (en) 2011-08-18 2013-02-21 Biodelivery Sciences International, Inc. Abuse-resistant mucoadhesive devices for delivery of buprenorphine
MX357423B (es) 2011-09-30 2018-07-09 Verde Environmental Tech Inc Sistema de desecho de medicamento general.
KR20140068058A (ko) 2011-09-30 2014-06-05 테이코쿠 팔마 유에스에이, 인코포레이티드 경피 패치 처리 시스템
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
WO2016049266A1 (en) * 2014-09-24 2016-03-31 Pain Therapeutics, Inc. 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal
US10010543B1 (en) 2014-12-23 2018-07-03 Barr Laboratories, Inc. Transdermal dosage form
WO2016123406A1 (en) 2015-01-28 2016-08-04 Chrono Therapeutics Inc. Drug delivery methods and systems
EP3267875A4 (de) 2015-03-12 2018-12-05 Chrono Therapeutics Inc. Eingabe- und unterstützungssystem für heftiges verlangen
US20190067725A1 (en) * 2016-02-26 2019-02-28 Case Western Reserve University Composite membranes for flow batteries
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11389844B2 (en) 2018-03-20 2022-07-19 Verde Environmental Technologies, Inc. Blister pack disposal system
CA3101966A1 (en) 2018-05-29 2019-12-05 Morningside Venture Investments Limited Drug delivery methods and systems
WO2020009685A1 (en) * 2018-07-02 2020-01-09 John Tang Transdermal dosage form
WO2020008366A1 (en) * 2018-07-02 2020-01-09 Clexio Biosciences Ltd. Transdermal dosage form
EP3870262A1 (de) * 2018-10-23 2021-09-01 Kindeva Drug Delivery L.P. Manipulationssicheres transdermales pflaster
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
US20220313686A1 (en) * 2019-08-12 2022-10-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Pharmaceutical compositions comprising a combination of opioid antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3643987A1 (de) * 1986-12-22 1988-06-23 Lohmann Therapie Syst Lts Basische, wirkstoffdurchlaessige haftklebende polymermasse, insbesondere zum einsatz mit basischen wirkstoffen, verfahren zu ihrer herstellung und ihre verwendung
US5236714A (en) * 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5149538A (en) * 1991-06-14 1992-09-22 Warner-Lambert Company Misuse-resistive transdermal opioid dosage form
US6096756A (en) * 1992-09-21 2000-08-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
US5573778A (en) * 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
WO1997004835A1 (de) * 1995-07-28 1997-02-13 Novartis Ag Transdermales system
US7011843B2 (en) * 1997-10-01 2006-03-14 Lts Lohmann-Therapie Systeme Ag Method for protecting a human being against health impairment by ingestion of a transdermal therapeutic system
CN1204890C (zh) * 1997-12-22 2005-06-08 欧罗赛铁克股份有限公司 防止阿片样物质滥用的方法
US6554851B1 (en) * 1999-05-07 2003-04-29 Scimed Life Systems, Inc. Methods of sealing an injection site
ATE459317T1 (de) * 2001-04-23 2010-03-15 Euro Celtique Sa Entsorgungssystem für transdermale dosierformen

Also Published As

Publication number Publication date
US20140199383A1 (en) 2014-07-17
PT2316439E (pt) 2015-08-28
EP1397095A4 (de) 2005-05-25
EP1397095B1 (de) 2008-12-03
EP2062573A1 (de) 2009-05-27
DK1397095T3 (da) 2009-03-09
WO2002087482A1 (en) 2002-11-07
JP5296284B2 (ja) 2013-09-25
EP2062573B1 (de) 2011-11-16
US20040241218A1 (en) 2004-12-02
ES2546828T3 (es) 2015-09-29
ATE533478T1 (de) 2011-12-15
EP2316439A1 (de) 2011-05-04
JP2004529155A (ja) 2004-09-24
DK2062573T3 (da) 2012-01-30
PT2062573E (pt) 2012-01-11
EP2316439B1 (de) 2015-06-17
DE60230138D1 (de) 2009-01-15
PT1397095E (pt) 2009-02-17
DK2316439T3 (en) 2015-08-10
CY1108821T1 (el) 2014-04-09
EP1397095A1 (de) 2004-03-17
JP2013144702A (ja) 2013-07-25
CY1112271T1 (el) 2015-12-09
SI1397095T1 (sl) 2009-04-30
JP2015042649A (ja) 2015-03-05
ES2318010T3 (es) 2009-05-01
ES2377672T3 (es) 2012-03-29
SI2316439T1 (sl) 2015-10-30
SI2062573T1 (sl) 2012-02-29

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