ATE415952T1 - Vor missbrauch geschützte opioid-haltige transdermale systeme - Google Patents

Vor missbrauch geschützte opioid-haltige transdermale systeme

Info

Publication number
ATE415952T1
ATE415952T1 AT02731653T AT02731653T ATE415952T1 AT E415952 T1 ATE415952 T1 AT E415952T1 AT 02731653 T AT02731653 T AT 02731653T AT 02731653 T AT02731653 T AT 02731653T AT E415952 T1 ATE415952 T1 AT E415952T1
Authority
AT
Austria
Prior art keywords
opioid
abuse
transdermal systems
containing transdermal
dosage form
Prior art date
Application number
AT02731653T
Other languages
English (en)
Inventor
Lino Tavares
Bruce Reidenberg
Richard Sackler
Curtis Wright
Mark A Alfonso
Benjamin Oshlack
James Cassidy
Anthony E Carpanzano
Rampurna Prasad Gullapalli
Ihor Shevchuk
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of ATE415952T1 publication Critical patent/ATE415952T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B2101/00—Type of solid waste
    • B09B2101/65—Medical waste
    • B09B2101/68—Transdermal patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02731653T 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme ATE415952T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28787501P 2001-05-01 2001-05-01
US29253701P 2001-05-22 2001-05-22

Publications (1)

Publication Number Publication Date
ATE415952T1 true ATE415952T1 (de) 2008-12-15

Family

ID=26964697

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02731653T ATE415952T1 (de) 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme
AT08020810T ATE533478T1 (de) 2001-05-01 2002-04-30 Missbrauchssichere opioide mit transdermalen systemen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT08020810T ATE533478T1 (de) 2001-05-01 2002-04-30 Missbrauchssichere opioide mit transdermalen systemen

Country Status (11)

Country Link
US (2) US20040241218A1 (de)
EP (3) EP2062573B1 (de)
JP (3) JP5296284B2 (de)
AT (2) ATE415952T1 (de)
CY (2) CY1108821T1 (de)
DE (1) DE60230138D1 (de)
DK (3) DK2316439T3 (de)
ES (3) ES2546828T3 (de)
PT (3) PT2062573E (de)
SI (3) SI2062573T1 (de)
WO (1) WO2002087482A1 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
US7125561B2 (en) * 2001-05-22 2006-10-24 Euro-Celtique S.A. Compartmentalized dosage form
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
CA2496454A1 (en) * 2002-04-23 2003-11-06 Alza Corporation Transdermal analgesic systems with reduced abuse potential
JP4949625B2 (ja) * 2002-06-10 2012-06-13 ユーロ−セルティーク エス．エイ． 経皮送達デバイスに含有された活性薬剤の誤用を防止する、経皮送達デバイスの廃棄システム
SI1551372T1 (en) * 2002-09-20 2018-08-31 Alpharma Pharmaceuticals Llc SUBVENCATION DATA AND RELATED CONSTRUCTIONS AND PROCEDURES
DE10250088A1 (de) * 2002-10-25 2004-05-06 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
BRPI0409945A (pt) * 2003-04-30 2006-04-25 Purdue Pharma Lp forma de dosagem resistente à alteração
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US7182955B2 (en) * 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
US20040219195A1 (en) * 2003-04-30 2004-11-04 3M Innovative Properties Company Abuse-resistant transdermal dosage form
CA2529983C (en) * 2003-07-25 2010-07-20 Euro-Celtique S.A. Preoperative treatment of post operative pain
US20070191815A1 (en) 2004-09-13 2007-08-16 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
AU2004286852A1 (en) * 2003-10-30 2005-05-19 Alza Corporation Transdermal analgesic systems having reduced abuse potential
US8535711B2 (en) * 2004-01-23 2013-09-17 Teikoku Pharma Usa, Inc. Medication disposal system
US7867511B2 (en) * 2004-01-23 2011-01-11 Travanti Pharma Inc. Abuse potential reduction in abusable substance dosage form
EP1718258B1 (de) * 2004-02-23 2009-03-25 Euro-Celtique S.A. Missbrauchsichere transdermale abgabevorrichtung für opioide, enthaltend opioidantagonist in form von mikrokügelchen
US20070269522A1 (en) * 2004-08-20 2007-11-22 Wold Chad R Transdermal Drug Delivery Device with Translucent Protective Film
US7226619B1 (en) 2004-09-07 2007-06-05 Pharmorx Inc. Material for controlling diversion of medications
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
ATE551995T1 (de) * 2004-10-21 2012-04-15 Durect Corp Transdermale abgabesysteme
WO2006069008A1 (en) * 2004-12-22 2006-06-29 Vesta Medical, Llc Compositions and devices for inactivation of pharmaceuticals to facilitate waste disposal, and methods thereof
US20060182819A1 (en) 2005-02-17 2006-08-17 Ough Yon D Soap scent patch and treatment for muscle spasm and pain
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
WO2006124749A2 (en) * 2005-05-13 2006-11-23 Alza Corporation Multilayer drug delivery system with barrier against antagonist exposure
DK1895994T3 (da) 2005-05-13 2010-12-20 Alza Corp Multilagsmedikamentleveringssystem med barriere mod reservoirmaterialeflow
US20070014839A1 (en) * 2005-07-18 2007-01-18 Stefan Bracht Decomposer film for transdermal patches
US9056061B2 (en) 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
EP2308480B1 (de) 2005-09-23 2014-08-13 ALZA Corporation Polyacrylatformulierung mit hoher Beladung von verstärkenden Substanzen für transdermale Anwendungen
US9522188B2 (en) * 2005-12-13 2016-12-20 Biodelivery Sciences International, Inc. Abuse resistant transmucosal drug delivery device
DE102006025282A1 (de) * 2006-05-31 2007-12-20 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System
SI2484346T1 (sl) 2006-06-19 2017-05-31 Alpharma Pharmaceuticals Llc Farmacevtski sestavki
US20080008747A1 (en) * 2006-07-07 2008-01-10 Royds Robert B Transdermal patch
ES2577390T3 (es) 2006-07-21 2016-07-14 Biodelivery Sciences International, Inc. Dispositivos de administración transmucosa con mayor captación
CA2665726C (en) * 2006-10-11 2016-04-19 Alpharma, Inc. Pharmaceutical compositions
US20080286348A1 (en) * 2007-05-16 2008-11-20 Todhunter John A Secured transdermal delivery system
DE102007041557B4 (de) * 2007-08-29 2011-03-31 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend längliche Hohlkörper
US20090196890A1 (en) * 2007-12-17 2009-08-06 Alpharma Pharmaceuticals, Llc Pharmaceutical compositions
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
CA2718943A1 (en) * 2008-03-26 2009-10-01 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
DE102008016804B4 (de) * 2008-04-02 2012-01-05 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System mit verbesserter Funktionalität und Wirksamkeit sowie seine Verwendung
EP3064199B1 (de) * 2010-04-02 2023-12-20 Buzzz Pharmaceuticals Limited Missbrauchssichere transdermale formulierungen von opiat-agonisten und -agonist-antagonisten
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
MX352959B (es) 2011-08-18 2017-12-15 Biodelivery Sciences Int Inc Dispositivos mucoadhesivos resistentes al abuso para el suministro de buprenorfina.
CN103764129A (zh) 2011-09-30 2014-04-30 帝国制药美国公司 透皮贴剂处置系统
CN103764092A (zh) 2011-09-30 2014-04-30 帝国制药美国公司 普通药物处置系统
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
WO2016049266A1 (en) * 2014-09-24 2016-03-31 Pain Therapeutics, Inc. 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal
US10010543B1 (en) 2014-12-23 2018-07-03 Barr Laboratories, Inc. Transdermal dosage form
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
KR20250011230A (ko) * 2016-02-26 2025-01-21 케이스 웨스턴 리저브 유니버시티 플로우 배터리용 복합 멤브레인
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11389844B2 (en) 2018-03-20 2022-07-19 Verde Environmental Technologies, Inc. Blister pack disposal system
AU2019279884B2 (en) 2018-05-29 2025-01-30 Morningside Venture Investments Limited Drug delivery methods and systems
WO2020009685A1 (en) * 2018-07-02 2020-01-09 John Tang Transdermal dosage form
WO2020008366A1 (en) * 2018-07-02 2020-01-09 Clexio Biosciences Ltd. Transdermal dosage form
WO2020084380A1 (en) * 2018-10-23 2020-04-30 3M Innovative Properties Company Tamper evident transdermal patch
JP2022507660A (ja) 2018-11-16 2022-01-18 モーニングサイド ベンチャー インベストメンツ リミテッド 温度によって調節される経皮薬剤送達システム
US20220313686A1 (en) * 2019-08-12 2022-10-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Pharmaceutical compositions comprising a combination of opioid antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3643987A1 (de) * 1986-12-22 1988-06-23 Lohmann Therapie Syst Lts Basische, wirkstoffdurchlaessige haftklebende polymermasse, insbesondere zum einsatz mit basischen wirkstoffen, verfahren zu ihrer herstellung und ihre verwendung
US5236714A (en) 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5149538A (en) 1991-06-14 1992-09-22 Warner-Lambert Company Misuse-resistive transdermal opioid dosage form
US6096756A (en) * 1992-09-21 2000-08-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
US5573778A (en) * 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
WO1997004835A1 (de) 1995-07-28 1997-02-13 Novartis Ag Transdermales system
US7011843B2 (en) * 1997-10-01 2006-03-14 Lts Lohmann-Therapie Systeme Ag Method for protecting a human being against health impairment by ingestion of a transdermal therapeutic system
CN1204890C (zh) 1997-12-22 2005-06-08 欧罗赛铁克股份有限公司 防止阿片样物质滥用的方法
US6554851B1 (en) * 1999-05-07 2003-04-29 Scimed Life Systems, Inc. Methods of sealing an injection site
DE60235555D1 (de) * 2001-04-23 2010-04-15 Euro Celtique Sa Entsorgungssystem für transdermale dosierformen

Also Published As

Publication number Publication date
WO2002087482A1 (en) 2002-11-07
DK1397095T3 (da) 2009-03-09
PT1397095E (pt) 2009-02-17
SI2316439T1 (sl) 2015-10-30
EP1397095A4 (de) 2005-05-25
PT2062573E (pt) 2012-01-11
JP2004529155A (ja) 2004-09-24
DK2062573T3 (da) 2012-01-30
ES2377672T3 (es) 2012-03-29
JP2015042649A (ja) 2015-03-05
SI1397095T1 (sl) 2009-04-30
DE60230138D1 (de) 2009-01-15
ES2546828T3 (es) 2015-09-29
EP1397095B1 (de) 2008-12-03
ES2318010T3 (es) 2009-05-01
JP2013144702A (ja) 2013-07-25
EP2062573A1 (de) 2009-05-27
DK2316439T3 (en) 2015-08-10
CY1112271T1 (el) 2015-12-09
EP1397095A1 (de) 2004-03-17
PT2316439E (pt) 2015-08-28
US20040241218A1 (en) 2004-12-02
EP2316439B1 (de) 2015-06-17
EP2062573B1 (de) 2011-11-16
SI2062573T1 (sl) 2012-02-29
ATE533478T1 (de) 2011-12-15
CY1108821T1 (el) 2014-04-09
EP2316439A1 (de) 2011-05-04
JP5296284B2 (ja) 2013-09-25
US20140199383A1 (en) 2014-07-17

Similar Documents

Publication Publication Date Title
DE60230138D1 (de) Vor missbrauch geschützte opioid-haltige transdermale systeme
DE60143360D1 (de) Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert
EA200600696A1 (ru) Фармацевтические композиции для предотвращения передозировки или неправильного употребления лекарственных средств
AU2002227913A1 (en) Synergistic medicament containing aromatic agents and having an antagonistic, regenerative and/or protagonist decontamination effect
DE60219627D1 (de) Nachweis und therapie von empfindlichem plaque mit photodynamischen verbindungen
ATE323071T1 (de) Substituierte phenolderivate und deren salze als hemmstoffe von koagulations faktor x
DE60132957D1 (de) Spielablaufverfahren, Spielsystem, und Server
DE60118885D1 (de) Nitratsalze von antimikrobiellen wirkstoffen
SE9901272D0 (sv) New improved formulation
DK0943328T3 (da) Kombinationsterapi til profylakse og/eller behandling af godartet prostatahyperplasi
EP1379232A4 (de) N-acetylcystein-zusammensetzungen und verfahren zur behandlung und prävention von arzneimitteltoxizität
DK1392328T3 (da) Medikament til beskyttelse i radioterapi
DE60135287D1 (de) Saugfähiger Einwegartikel und Schutzmittel
BR0013009A (pt) Uso de antagonistas de cgrp e de inibidores de liberação de cgrp para combate a jatos quentes menopáusicos
FR2760972B1 (fr) Utilisation de l-citrulline en medecine orthomoleculaire pour la vasoprotection, le tonus relaxatif des muscles lisses et la protection cellulaires
DE60233891D1 (de) Selektives targeting von apoptotischen zellen
MXPA03011825A (es) Combinacion de ingrediente activo para tratar una dependencia de sustancias aditivas o narcoticas utilizando medicamentos.
ATE458750T1 (de) Antivirale mittel zur behandlung, kontrolle und prävention von infektionen durch coronaviren
NO20032597D0 (no) Anvendelse av SARP-1 for behandlingen og/eller forebyggingen av skleroderma
SE0103276D0 (sv) Anordning för administrering av salva till en hudyta
PT1200071E (pt) Comprimidos fracamente doseados e processo de preparacao
TR200000005T2 (tr) Sıtmaya karşı ß-alkoksiakrilatlar.
DK1156829T3 (da) Stabil formulering indeholdende fumagillin
WO2002028399A1 (fr) Inducteurs de l'apoptose, activateurs de cascade de caspase et agents anticancers
PT1206267E (pt) Medicamentos contendo oligo-ou/e polirribonucleotidos xenogenicos

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1397095

Country of ref document: EP