ATE533478T1 - Missbrauchssichere opioide mit transdermalen systemen - Google Patents

Missbrauchssichere opioide mit transdermalen systemen

Info

Publication number
ATE533478T1
ATE533478T1 AT08020810T AT08020810T ATE533478T1 AT E533478 T1 ATE533478 T1 AT E533478T1 AT 08020810 T AT08020810 T AT 08020810T AT 08020810 T AT08020810 T AT 08020810T AT E533478 T1 ATE533478 T1 AT E533478T1
Authority
AT
Austria
Prior art keywords
opioids
abuse
proof
transdermal systems
dosage form
Prior art date
Application number
AT08020810T
Other languages
English (en)
Inventor
Lino Tavares
Bruce E Reidenberg
Richard S Sackler
Curtis Wright
Mark A Alfonso
Benjamin Oshlack
James P Cassidy
Anthony E Carpanzano
Rampurna Prasad Gullapalli
Ihor Shevchuk
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of ATE533478T1 publication Critical patent/ATE533478T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B2101/00—Type of solid waste
    • B09B2101/65—Medical waste
    • B09B2101/68—Transdermal patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT08020810T 2001-05-01 2002-04-30 Missbrauchssichere opioide mit transdermalen systemen ATE533478T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28787501P 2001-05-01 2001-05-01
US29253701P 2001-05-22 2001-05-22

Publications (1)

Publication Number Publication Date
ATE533478T1 true ATE533478T1 (de) 2011-12-15

Family

ID=26964697

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02731653T ATE415952T1 (de) 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme
AT08020810T ATE533478T1 (de) 2001-05-01 2002-04-30 Missbrauchssichere opioide mit transdermalen systemen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02731653T ATE415952T1 (de) 2001-05-01 2002-04-30 Vor missbrauch geschützte opioid-haltige transdermale systeme

Country Status (11)

Country Link
US (2) US20040241218A1 (de)
EP (3) EP2062573B1 (de)
JP (3) JP5296284B2 (de)
AT (2) ATE415952T1 (de)
CY (2) CY1108821T1 (de)
DE (1) DE60230138D1 (de)
DK (3) DK2316439T3 (de)
ES (3) ES2546828T3 (de)
PT (3) PT2062573E (de)
SI (3) SI2062573T1 (de)
WO (1) WO2002087482A1 (de)

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CA2496454A1 (en) * 2002-04-23 2003-11-06 Alza Corporation Transdermal analgesic systems with reduced abuse potential
JP4949625B2 (ja) * 2002-06-10 2012-06-13 ユーロ−セルティーク エス．エイ． 経皮送達デバイスに含有された活性薬剤の誤用を防止する、経皮送達デバイスの廃棄システム
SI1551372T1 (en) * 2002-09-20 2018-08-31 Alpharma Pharmaceuticals Llc SUBVENCATION DATA AND RELATED CONSTRUCTIONS AND PROCEDURES
DE10250088A1 (de) * 2002-10-25 2004-05-06 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
BRPI0409945A (pt) * 2003-04-30 2006-04-25 Purdue Pharma Lp forma de dosagem resistente à alteração
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US7182955B2 (en) * 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
US20040219195A1 (en) * 2003-04-30 2004-11-04 3M Innovative Properties Company Abuse-resistant transdermal dosage form
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US20070191815A1 (en) 2004-09-13 2007-08-16 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
AU2004286852A1 (en) * 2003-10-30 2005-05-19 Alza Corporation Transdermal analgesic systems having reduced abuse potential
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US7867511B2 (en) * 2004-01-23 2011-01-11 Travanti Pharma Inc. Abuse potential reduction in abusable substance dosage form
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US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
ATE551995T1 (de) * 2004-10-21 2012-04-15 Durect Corp Transdermale abgabesysteme
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US20060182819A1 (en) 2005-02-17 2006-08-17 Ough Yon D Soap scent patch and treatment for muscle spasm and pain
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
WO2006124749A2 (en) * 2005-05-13 2006-11-23 Alza Corporation Multilayer drug delivery system with barrier against antagonist exposure
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US20070014839A1 (en) * 2005-07-18 2007-01-18 Stefan Bracht Decomposer film for transdermal patches
US9056061B2 (en) 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
EP2308480B1 (de) 2005-09-23 2014-08-13 ALZA Corporation Polyacrylatformulierung mit hoher Beladung von verstärkenden Substanzen für transdermale Anwendungen
US9522188B2 (en) * 2005-12-13 2016-12-20 Biodelivery Sciences International, Inc. Abuse resistant transmucosal drug delivery device
DE102006025282A1 (de) * 2006-05-31 2007-12-20 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System
SI2484346T1 (sl) 2006-06-19 2017-05-31 Alpharma Pharmaceuticals Llc Farmacevtski sestavki
US20080008747A1 (en) * 2006-07-07 2008-01-10 Royds Robert B Transdermal patch
ES2577390T3 (es) 2006-07-21 2016-07-14 Biodelivery Sciences International, Inc. Dispositivos de administración transmucosa con mayor captación
CA2665726C (en) * 2006-10-11 2016-04-19 Alpharma, Inc. Pharmaceutical compositions
US20080286348A1 (en) * 2007-05-16 2008-11-20 Todhunter John A Secured transdermal delivery system
DE102007041557B4 (de) * 2007-08-29 2011-03-31 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend längliche Hohlkörper
US20090196890A1 (en) * 2007-12-17 2009-08-06 Alpharma Pharmaceuticals, Llc Pharmaceutical compositions
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
CA2718943A1 (en) * 2008-03-26 2009-10-01 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
DE102008016804B4 (de) * 2008-04-02 2012-01-05 Lts Lohmann Therapie-Systeme Ag Selbstzerstörendes transdermales therapeutisches System mit verbesserter Funktionalität und Wirksamkeit sowie seine Verwendung
EP3064199B1 (de) * 2010-04-02 2023-12-20 Buzzz Pharmaceuticals Limited Missbrauchssichere transdermale formulierungen von opiat-agonisten und -agonist-antagonisten
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
MX352959B (es) 2011-08-18 2017-12-15 Biodelivery Sciences Int Inc Dispositivos mucoadhesivos resistentes al abuso para el suministro de buprenorfina.
CN103764129A (zh) 2011-09-30 2014-04-30 帝国制药美国公司 透皮贴剂处置系统
CN103764092A (zh) 2011-09-30 2014-04-30 帝国制药美国公司 普通药物处置系统
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
WO2016049266A1 (en) * 2014-09-24 2016-03-31 Pain Therapeutics, Inc. 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal
US10010543B1 (en) 2014-12-23 2018-07-03 Barr Laboratories, Inc. Transdermal dosage form
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
KR20250011230A (ko) * 2016-02-26 2025-01-21 케이스 웨스턴 리저브 유니버시티 플로우 배터리용 복합 멤브레인
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11389844B2 (en) 2018-03-20 2022-07-19 Verde Environmental Technologies, Inc. Blister pack disposal system
AU2019279884B2 (en) 2018-05-29 2025-01-30 Morningside Venture Investments Limited Drug delivery methods and systems
WO2020009685A1 (en) * 2018-07-02 2020-01-09 John Tang Transdermal dosage form
WO2020008366A1 (en) * 2018-07-02 2020-01-09 Clexio Biosciences Ltd. Transdermal dosage form
WO2020084380A1 (en) * 2018-10-23 2020-04-30 3M Innovative Properties Company Tamper evident transdermal patch
JP2022507660A (ja) 2018-11-16 2022-01-18 モーニングサイド ベンチャー インベストメンツ リミテッド 温度によって調節される経皮薬剤送達システム
US20220313686A1 (en) * 2019-08-12 2022-10-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Pharmaceutical compositions comprising a combination of opioid antagonists

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DE3643987A1 (de) * 1986-12-22 1988-06-23 Lohmann Therapie Syst Lts Basische, wirkstoffdurchlaessige haftklebende polymermasse, insbesondere zum einsatz mit basischen wirkstoffen, verfahren zu ihrer herstellung und ihre verwendung
US5236714A (en) 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
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Also Published As

Publication number Publication date
WO2002087482A1 (en) 2002-11-07
DK1397095T3 (da) 2009-03-09
PT1397095E (pt) 2009-02-17
SI2316439T1 (sl) 2015-10-30
EP1397095A4 (de) 2005-05-25
PT2062573E (pt) 2012-01-11
JP2004529155A (ja) 2004-09-24
DK2062573T3 (da) 2012-01-30
ES2377672T3 (es) 2012-03-29
JP2015042649A (ja) 2015-03-05
SI1397095T1 (sl) 2009-04-30
DE60230138D1 (de) 2009-01-15
ES2546828T3 (es) 2015-09-29
ATE415952T1 (de) 2008-12-15
EP1397095B1 (de) 2008-12-03
ES2318010T3 (es) 2009-05-01
JP2013144702A (ja) 2013-07-25
EP2062573A1 (de) 2009-05-27
DK2316439T3 (en) 2015-08-10
CY1112271T1 (el) 2015-12-09
EP1397095A1 (de) 2004-03-17
PT2316439E (pt) 2015-08-28
US20040241218A1 (en) 2004-12-02
EP2316439B1 (de) 2015-06-17
EP2062573B1 (de) 2011-11-16
SI2062573T1 (sl) 2012-02-29
CY1108821T1 (el) 2014-04-09
EP2316439A1 (de) 2011-05-04
JP5296284B2 (ja) 2013-09-25
US20140199383A1 (en) 2014-07-17

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