DK1383919T3 - Fremgangsmåder og sammensætninger til anvendelse af MHC klasse II-invariant kædepolypeptid som en receptor for makrofag migrationsinhiberede faktor - Google Patents

Fremgangsmåder og sammensætninger til anvendelse af MHC klasse II-invariant kædepolypeptid som en receptor for makrofag migrationsinhiberede faktor

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Publication number
DK1383919T3
DK1383919T3 DK02725395.4T DK02725395T DK1383919T3 DK 1383919 T3 DK1383919 T3 DK 1383919T3 DK 02725395 T DK02725395 T DK 02725395T DK 1383919 T3 DK1383919 T3 DK 1383919T3
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Prior art keywords
receptor
compositions
methods
chain polypeptide
inhibitory factor
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DK02725395.4T
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Danish (da)
English (en)
Inventor
Richard J Bucala
Seamas Donnelly
Lin Leng
Christine N Metz
Robert Mitchell
Original Assignee
Cytokine Pharmasciences Inc
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Publication of DK1383919T3 publication Critical patent/DK1383919T3/da

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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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DK02725395.4T 2001-03-29 2002-03-29 Fremgangsmåder og sammensætninger til anvendelse af MHC klasse II-invariant kædepolypeptid som en receptor for makrofag migrationsinhiberede faktor DK1383919T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27943501P 2001-03-29 2001-03-29
PCT/US2002/009580 WO2002079517A1 (en) 2001-03-29 2002-03-29 Methods and compositions for using mhc class ii invariant chain polypeptide as a receptor for macrophage migration inhibitory factor

Publications (1)

Publication Number Publication Date
DK1383919T3 true DK1383919T3 (da) 2010-11-08

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DK02725395.4T DK1383919T3 (da) 2001-03-29 2002-03-29 Fremgangsmåder og sammensætninger til anvendelse af MHC klasse II-invariant kædepolypeptid som en receptor for makrofag migrationsinhiberede faktor

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Country Link
US (10) US20030013122A1 (enExample)
EP (1) EP1383919B1 (enExample)
JP (1) JP4202763B2 (enExample)
AT (1) ATE473294T1 (enExample)
AU (1) AU2002255961B2 (enExample)
CA (1) CA2455915C (enExample)
DE (1) DE60236921D1 (enExample)
DK (1) DK1383919T3 (enExample)
ES (1) ES2352228T3 (enExample)
WO (1) WO2002079517A1 (enExample)

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WO2006102191A1 (en) 2005-03-24 2006-09-28 Avanir Pharmaceuticals Thienopyridinone derivatives as macrophage migration inhibitory factor inhibitors
WO2007044622A1 (en) 2005-10-07 2007-04-19 Yale University Use of mif and mif pathway agonists
WO2013010955A1 (en) 2011-07-15 2013-01-24 Morphosys Ag Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt)
EP2734228A4 (en) 2011-07-18 2015-04-08 Ohio State Innovation Foundation FTY720 INCREASES CD74 RECEPTOR EXPRESSION AND SENSITIZES CANCER CELLS TO CELL DEATH INDUCED BY ANTI-CD74 ANTIBODIES
WO2013050453A1 (en) 2011-10-07 2013-04-11 Baxter Healthcare S.A. Oxmif as a diagnostic marker
WO2014127200A1 (en) 2013-02-15 2014-08-21 Immunomedics, Inc. Chimeric and humanized anti-histone antibodies
US10316075B2 (en) 2013-10-03 2019-06-11 Oregon Health & Science University Recombinant polypeptides comprising MHC class II α1 domains
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US10351621B2 (en) 2014-06-24 2019-07-16 Immunomedics, Inc. Anti-histone therapy in acute kidney injury
WO2015200260A1 (en) 2014-06-24 2015-12-30 Immunomedics, Inc. Anti-histone therapy for vascular necrosis in severe glomerulonephritis
WO2016057702A2 (en) 2014-10-07 2016-04-14 Cornell University Methods for prognosing and preventing metastatic liver disease
US10525101B2 (en) 2015-10-23 2020-01-07 Oregon Health & Science University Methods of treating inflammatory or autoimmune disorders with compounds that bind macrophage migration inhibitory factor
WO2018187074A1 (en) 2017-04-03 2018-10-11 Immunomedics, Inc. Subcutaneous administration of antibody-drug conjugates for cancer therapy
CN114668832A (zh) * 2022-04-27 2022-06-28 西安市第一医院 Mif及其受体cd74制备调控细胞功能和分裂增殖药物中的应用

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EP1383919A4 (en) 2004-12-01
JP2004532839A (ja) 2004-10-28
US7741057B2 (en) 2010-06-22
US20120039914A1 (en) 2012-02-16
US20090263404A1 (en) 2009-10-22
US20080146507A1 (en) 2008-06-19
CA2455915A1 (en) 2002-10-10
ES2352228T3 (es) 2011-02-16
WO2002079517A1 (en) 2002-10-10
US20030013122A1 (en) 2003-01-16
EP1383919B1 (en) 2010-07-07
JP4202763B2 (ja) 2008-12-24
US9221903B2 (en) 2015-12-29
US20140178403A1 (en) 2014-06-26
US8779099B2 (en) 2014-07-15
CA2455915C (en) 2013-05-14
US20150010570A1 (en) 2015-01-08
ATE473294T1 (de) 2010-07-15
US8617822B2 (en) 2013-12-31
US20180105593A1 (en) 2018-04-19
US20160152708A1 (en) 2016-06-02
US20060024754A1 (en) 2006-02-02
US20110020321A1 (en) 2011-01-27
EP1383919A1 (en) 2004-01-28
AU2002255961B2 (en) 2007-08-23

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