DK1381613T3 - Antidepressive azaheterocyclylmethylderivater af oxaheterocyclokondenserede 1,4-benzodioxaner - Google Patents
Antidepressive azaheterocyclylmethylderivater af oxaheterocyclokondenserede 1,4-benzodioxanerInfo
- Publication number
- DK1381613T3 DK1381613T3 DK02728947T DK02728947T DK1381613T3 DK 1381613 T3 DK1381613 T3 DK 1381613T3 DK 02728947 T DK02728947 T DK 02728947T DK 02728947 T DK02728947 T DK 02728947T DK 1381613 T3 DK1381613 T3 DK 1381613T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxaheterocyclo
- benzodioxanes
- azaheterocyclyl
- antidepressant
- condensed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28656901P | 2001-04-26 | 2001-04-26 | |
PCT/US2002/012831 WO2002088135A1 (en) | 2001-04-26 | 2002-04-24 | Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1381613T3 true DK1381613T3 (da) | 2005-01-24 |
Family
ID=23099201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02728947T DK1381613T3 (da) | 2001-04-26 | 2002-04-24 | Antidepressive azaheterocyclylmethylderivater af oxaheterocyclokondenserede 1,4-benzodioxaner |
Country Status (12)
Country | Link |
---|---|
US (1) | US6552049B2 (de) |
EP (1) | EP1381613B1 (de) |
JP (1) | JP2004532236A (de) |
CN (1) | CN1503798A (de) |
AT (1) | ATE279415T1 (de) |
BR (1) | BR0209343A (de) |
CA (1) | CA2445543A1 (de) |
DE (1) | DE60201590T2 (de) |
DK (1) | DK1381613T3 (de) |
ES (1) | ES2229138T3 (de) |
MX (1) | MXPA03009825A (de) |
WO (1) | WO2002088135A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6706736B2 (en) * | 2001-04-26 | 2004-03-16 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans |
US6911445B2 (en) | 2002-09-12 | 2005-06-28 | Wyeth | Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans |
CN101676285A (zh) | 2004-03-30 | 2010-03-24 | 沃泰克斯药物股份有限公司 | 用作jak和其它蛋白激酶抑制剂的氮杂吲哚 |
JP2005314260A (ja) * | 2004-04-28 | 2005-11-10 | Japan Science & Technology Agency | フラボンc配糖体の製法 |
BRPI0608353A2 (pt) * | 2005-02-17 | 2009-12-01 | Wyeth Corp | derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos |
CN101678022A (zh) | 2006-12-21 | 2010-03-24 | 弗特克斯药品有限公司 | 可用作蛋白激酶抑制剂的5-氰基-4-(吡咯并[2,3b]吡啶-3-基)嘧啶衍生物 |
NZ619259A (en) | 2009-06-17 | 2015-07-31 | Vertex Pharma | Inhibitors of influenza viruses replication |
CN103492381A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
CN105849100B (zh) | 2013-11-13 | 2019-07-16 | 沃泰克斯药物股份有限公司 | 流感病毒复制抑制剂 |
CA2930297C (en) | 2013-11-13 | 2022-04-05 | Vertex Pharmaceuticals Incorporated | Methods of preparing inhibitors of influenza viruses replication |
JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤 |
JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤を調製する方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4135474A1 (de) | 1991-10-28 | 1993-04-29 | Bayer Ag | 2-aminomethyl-chromane |
DE4140540A1 (de) | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
ATE256130T1 (de) | 1993-08-19 | 2003-12-15 | Janssen Pharmaceutica Nv | Gefässverengende dihydrobenzopyranderivate |
US5741789A (en) | 1995-01-17 | 1998-04-21 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
GB9526495D0 (en) | 1995-12-23 | 1996-02-28 | Knoll Ag | Therapeutic agents |
DK0932609T3 (da) * | 1996-10-15 | 2003-09-01 | Wyeth Corp | Azaheterocyclomethylderivater af 2,3,8,9-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-on |
US5869490A (en) | 1996-10-15 | 1999-02-09 | American Home Products Corporation | Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one |
GB9627005D0 (en) | 1996-12-27 | 1997-02-12 | Knoll Ag | Therapeutic agents |
GB9704948D0 (en) * | 1997-03-11 | 1997-04-30 | Knoll Ag | Therapeutic agents |
AU8743098A (en) | 1997-08-22 | 1999-03-16 | Eli Lilly And Company Limited | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands |
US6458802B1 (en) * | 2001-03-14 | 2002-10-01 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline |
-
2002
- 2002-04-24 WO PCT/US2002/012831 patent/WO2002088135A1/en active IP Right Grant
- 2002-04-24 MX MXPA03009825A patent/MXPA03009825A/es unknown
- 2002-04-24 DE DE60201590T patent/DE60201590T2/de not_active Expired - Fee Related
- 2002-04-24 ES ES02728947T patent/ES2229138T3/es not_active Expired - Lifetime
- 2002-04-24 EP EP02728947A patent/EP1381613B1/de not_active Expired - Lifetime
- 2002-04-24 DK DK02728947T patent/DK1381613T3/da active
- 2002-04-24 US US10/131,340 patent/US6552049B2/en not_active Expired - Fee Related
- 2002-04-24 AT AT02728947T patent/ATE279415T1/de not_active IP Right Cessation
- 2002-04-24 CA CA002445543A patent/CA2445543A1/en not_active Abandoned
- 2002-04-24 CN CNA028086473A patent/CN1503798A/zh active Pending
- 2002-04-24 JP JP2002585434A patent/JP2004532236A/ja active Pending
- 2002-04-24 BR BR0209343-0A patent/BR0209343A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1381613A1 (de) | 2004-01-21 |
US6552049B2 (en) | 2003-04-22 |
WO2002088135A1 (en) | 2002-11-07 |
ES2229138T3 (es) | 2005-04-16 |
DE60201590D1 (de) | 2004-11-18 |
EP1381613B1 (de) | 2004-10-13 |
US20020183353A1 (en) | 2002-12-05 |
JP2004532236A (ja) | 2004-10-21 |
ATE279415T1 (de) | 2004-10-15 |
CA2445543A1 (en) | 2002-11-07 |
DE60201590T2 (de) | 2005-02-17 |
CN1503798A (zh) | 2004-06-09 |
BR0209343A (pt) | 2004-06-15 |
MXPA03009825A (es) | 2005-03-07 |
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