DK1378245T3 - Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine - Google Patents
Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccineInfo
- Publication number
- DK1378245T3 DK1378245T3 DK02028655T DK02028655T DK1378245T3 DK 1378245 T3 DK1378245 T3 DK 1378245T3 DK 02028655 T DK02028655 T DK 02028655T DK 02028655 T DK02028655 T DK 02028655T DK 1378245 T3 DK1378245 T3 DK 1378245T3
- Authority
- DK
- Denmark
- Prior art keywords
- neisseria
- neisseria gonorrhoeae
- iron
- regulated
- outer membrane
- Prior art date
Links
- 241000588652 Neisseria gonorrhoeae Species 0.000 title abstract 5
- 241000588650 Neisseria meningitidis Species 0.000 title abstract 3
- 102000010912 Transferrin-Binding Proteins Human genes 0.000 title 1
- 108010062476 Transferrin-Binding Proteins Proteins 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 4
- 101001056675 Klebsiella pneumoniae Ferric aerobactin receptor Proteins 0.000 abstract 2
- 101710116435 Outer membrane protein Proteins 0.000 abstract 2
- 229910052742 iron Inorganic materials 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108020003175 receptors Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57218790A | 1990-08-23 | 1990-08-23 | |
| PCT/US1991/006026 WO1992003467A1 (en) | 1990-08-23 | 1991-08-23 | Transferrin binding proteins from neisseria gonorrhoeae and neisseria meningitidis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1378245T3 true DK1378245T3 (da) | 2009-10-26 |
Family
ID=24286735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02028655T DK1378245T3 (da) | 1990-08-23 | 1991-08-23 | Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine |
| DK91918802T DK0546118T3 (da) | 1990-08-23 | 1991-08-23 | Transferrinbindende proteiner fra Neisseria gonorrhoeae og Neisseria meningtidis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91918802T DK0546118T3 (da) | 1990-08-23 | 1991-08-23 | Transferrinbindende proteiner fra Neisseria gonorrhoeae og Neisseria meningtidis |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7582730B2 (ja) |
| EP (2) | EP1378245B1 (ja) |
| JP (3) | JP3532563B2 (ja) |
| AT (2) | ATE439859T1 (ja) |
| AU (1) | AU8747791A (ja) |
| CA (1) | CA2087958C (ja) |
| DE (2) | DE69133334T2 (ja) |
| DK (2) | DK1378245T3 (ja) |
| ES (2) | ES2210228T3 (ja) |
| WO (1) | WO1992003467A1 (ja) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6086896A (en) * | 1990-07-16 | 2000-07-11 | Imclone Systems Incorporated | Antigenic iron repressible protein from N. meningitidis related to the hemolysin family of toxins |
| US6887482B2 (en) | 1990-07-16 | 2005-05-03 | The University Of North Carolina At Chapel Hill | Antigenic iron repressible proteins from N. meningitidis related to the hemolysin family of toxins |
| FR2682114B1 (fr) * | 1991-10-03 | 1996-02-23 | Pasteur Merieux Serums Vacc | Vaccin de sous-unite contre les infections a neisseria meningitidis et sous-unites correspondantes a l'etat purifie. |
| FR2692592B1 (fr) * | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant. |
| US5439808A (en) * | 1993-07-23 | 1995-08-08 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
| FR2724936A1 (fr) * | 1994-09-22 | 1996-03-29 | Pasteur Merieux Serums Vacc | Recepteur lactoferrine d'helicobacter |
| US5747287A (en) * | 1995-04-28 | 1998-05-05 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
| AU3657995A (en) * | 1995-10-09 | 1997-04-30 | Pasteur Merieux Serums Et Vaccins | Helicobacter lactoferrin receptor |
| US6610506B1 (en) | 1995-12-01 | 2003-08-26 | University Technologies International, Inc. | Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same |
| GB9726398D0 (en) | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| EP2261346A3 (en) * | 1998-05-01 | 2012-01-04 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| US6692752B1 (en) | 1999-09-08 | 2004-02-17 | Smithkline Beecham Biologicals S.A. | Methods of treating human females susceptible to HSV infection |
| US6610306B2 (en) | 1998-10-22 | 2003-08-26 | The University Of Montana | OMP85 protein of neisseria meningitidis, compositions containing the same and methods of use thereof |
| DK1535928T3 (da) * | 1998-10-22 | 2008-10-20 | Univ Montana | Vaccinesammensætninger indeholdende Omp85-proteiner af Neisseria gonorrhoeae og Neisseria meningitidis |
| DE69839740D1 (de) | 1998-10-22 | 2008-08-28 | Univ Montana | Vakzine enthaltend Omp85 Proteine von Neisseria gonorrhoeae und Neisseria meningitidis |
| PT1535928E (pt) * | 1998-10-22 | 2008-10-08 | Univ Montana | Composições de vacina compreendendo proteínas omp85 de neisseria gonorrhoeae e neisseria meningitidis |
| EP1069133A1 (en) * | 1999-07-13 | 2001-01-17 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Neisseria meningitidis compounds and anti-infection applications thereof |
| CA2954411A1 (en) * | 1999-10-29 | 2001-05-03 | Novartis Vaccines And Diagnostics S.R.L. | Neisserial antigenic peptides |
| JP4740738B2 (ja) | 2002-08-02 | 2011-08-03 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| BR0315767A (pt) | 2002-11-01 | 2005-09-06 | Glaxosmithkline Biolog Sa | Composição imunogência, método para fabricar uma vacina, kit, vacina, recipiente com uma superfìcie interna repelente à água, e, método para preservar uma composição que compreende ipv e um agente estabilizador |
| CA2539715C (en) | 2003-10-02 | 2015-02-24 | Glaxosmithkline Biologicals S.A. | Pertussis antigens and use thereof in vaccination |
| EP1670506B1 (en) | 2003-10-02 | 2012-11-21 | Novartis AG | Liquid vaccines for multiple meningococcal serogroups |
| GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
| EP2032161B1 (en) | 2006-06-12 | 2012-07-11 | GlaxoSmithKline Biologicals S.A. | L3v los vaccines |
| GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
| BR112012022688A2 (pt) | 2010-03-10 | 2018-05-22 | Glaxosmithkline Biologicals Sa | proteína de fusão, vesícula da membrana externa isolada, polinucleotídeo, composição farmacêutica, vacina, método para tratamento ou prevenção de infecção ou doença por neisseria, uso e método para fabricar uma proteína de fusão |
| CN110251668A (zh) | 2010-11-30 | 2019-09-20 | 霍夫曼-拉罗奇有限公司 | 低亲和力血脑屏障受体抗体及其用途 |
| US20190233876A1 (en) * | 2016-07-18 | 2019-08-01 | Cell Idx, Inc. | Antigen-coupled hybridization reagents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4681761A (en) * | 1985-10-24 | 1987-07-21 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine |
| US5292869A (en) * | 1989-04-27 | 1994-03-08 | The Board Of Governors Of The University | Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same |
| US5141743A (en) * | 1989-04-27 | 1992-08-25 | University Technologies International, Inc. | Method for isolating and purifying transferrin and lactoferrin receptor proteins and vaccines containing the same |
| US5912336A (en) * | 1990-08-23 | 1999-06-15 | University Of North Carolina At Chapel Hill | Isolated nucleic acid molecules encoding transferrin binding proteins from Neisseria gonorrhoeae and Neisseria meningitidis |
| FR2692592B1 (fr) | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant. |
-
1991
- 1991-08-23 DK DK02028655T patent/DK1378245T3/da active
- 1991-08-23 EP EP02028655A patent/EP1378245B1/en not_active Expired - Lifetime
- 1991-08-23 AT AT02028655T patent/ATE439859T1/de not_active IP Right Cessation
- 1991-08-23 ES ES91918802T patent/ES2210228T3/es not_active Expired - Lifetime
- 1991-08-23 DK DK91918802T patent/DK0546118T3/da active
- 1991-08-23 AU AU87477/91A patent/AU8747791A/en not_active Abandoned
- 1991-08-23 AT AT91918802T patent/ATE253114T1/de not_active IP Right Cessation
- 1991-08-23 DE DE69133334T patent/DE69133334T2/de not_active Expired - Lifetime
- 1991-08-23 CA CA002087958A patent/CA2087958C/en not_active Expired - Lifetime
- 1991-08-23 WO PCT/US1991/006026 patent/WO1992003467A1/en active IP Right Grant
- 1991-08-23 ES ES02028655T patent/ES2329979T3/es not_active Expired - Lifetime
- 1991-08-23 DE DE69133622T patent/DE69133622D1/de not_active Expired - Lifetime
- 1991-08-23 JP JP51718491A patent/JP3532563B2/ja not_active Expired - Lifetime
- 1991-08-23 EP EP91918802A patent/EP0546118B1/en not_active Expired - Lifetime
-
2001
- 2001-09-27 JP JP2001296757A patent/JP2002186489A/ja active Pending
-
2003
- 2003-05-20 JP JP2003141370A patent/JP2005239548A/ja active Pending
-
2004
- 2004-08-30 US US10/928,311 patent/US7582730B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7582730B2 (en) | 2009-09-01 |
| EP0546118A1 (en) | 1993-06-16 |
| CA2087958C (en) | 2007-05-15 |
| ES2210228T3 (es) | 2004-07-01 |
| JP2005239548A (ja) | 2005-09-08 |
| DE69133334T2 (de) | 2004-05-13 |
| DK0546118T3 (da) | 2004-02-16 |
| JPH06500562A (ja) | 1994-01-20 |
| DE69133622D1 (de) | 2009-10-01 |
| AU8747791A (en) | 1992-03-17 |
| WO1992003467A1 (en) | 1992-03-05 |
| JP2002186489A (ja) | 2002-07-02 |
| EP1378245A3 (en) | 2004-01-14 |
| JP3532563B2 (ja) | 2004-05-31 |
| DE69133334D1 (de) | 2003-12-04 |
| EP0546118B1 (en) | 2003-10-29 |
| ATE439859T1 (de) | 2009-09-15 |
| EP1378245B1 (en) | 2009-08-19 |
| ES2329979T3 (es) | 2009-12-03 |
| EP1378245A2 (en) | 2004-01-07 |
| CA2087958A1 (en) | 1992-02-24 |
| ATE253114T1 (de) | 2003-11-15 |
| EP0546118A4 (en) | 1993-07-14 |
| US20070065453A1 (en) | 2007-03-22 |
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