DK0579640T3 - Glialmitogene faktorer samt deres fremstilling og anvendelse - Google Patents

Glialmitogene faktorer samt deres fremstilling og anvendelse

Info

Publication number
DK0579640T3
DK0579640T3 DK92907539T DK92907539T DK0579640T3 DK 0579640 T3 DK0579640 T3 DK 0579640T3 DK 92907539 T DK92907539 T DK 92907539T DK 92907539 T DK92907539 T DK 92907539T DK 0579640 T3 DK0579640 T3 DK 0579640T3
Authority
DK
Denmark
Prior art keywords
factors
preparation
well
mitogenic factors
factor
Prior art date
Application number
DK92907539T
Other languages
English (en)
Inventor
Andrew David John Goodearl
Michael Derek Waterfield
Paul Stroobant
Luisa Minghetti
Mark Andrew Marchionni
Original Assignee
Cambridge Neuroscience Res Inc
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Neuroscience Res Inc, Ludwig Inst Cancer Res filed Critical Cambridge Neuroscience Res Inc
Application granted granted Critical
Publication of DK0579640T3 publication Critical patent/DK0579640T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK92907539T 1991-04-10 1992-04-03 Glialmitogene faktorer samt deres fremstilling og anvendelse DK0579640T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919107566A GB9107566D0 (en) 1991-04-10 1991-04-10 Glial mitogenic factors,their preparation and use
PCT/GB1992/000595 WO1992018627A1 (en) 1991-04-10 1992-04-03 Glial mitogenic factors, their preparation and use

Publications (1)

Publication Number Publication Date
DK0579640T3 true DK0579640T3 (da) 2002-11-11

Family

ID=10692987

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92907539T DK0579640T3 (da) 1991-04-10 1992-04-03 Glialmitogene faktorer samt deres fremstilling og anvendelse

Country Status (13)

Country Link
EP (1) EP0579640B1 (da)
JP (1) JPH06507544A (da)
KR (1) KR100274305B1 (da)
AT (1) ATE221083T1 (da)
AU (2) AU1450992A (da)
CA (1) CA2108119C (da)
DE (1) DE69232693T2 (da)
DK (1) DK0579640T3 (da)
GB (1) GB9107566D0 (da)
IE (1) IE921062A1 (da)
PT (1) PT100344B (da)
WO (1) WO1992018627A1 (da)
ZA (1) ZA922441B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US5367060A (en) * 1991-05-24 1994-11-22 Genentech, Inc. Structure, production and use of heregulin
US5834229A (en) * 1991-05-24 1998-11-10 Genentech, Inc. Nucleic acids vectors and host cells encoding and expressing heregulin 2-α
IL101943A0 (en) * 1991-05-24 1992-12-30 Genentech Inc Structure,production and use of heregulin
WO1994003644A1 (en) * 1992-08-10 1994-02-17 Cambridge Neuroscience, Inc. Inhibitors of cell proliferation, their preparation and use
GB9217316D0 (en) * 1992-08-14 1992-09-30 Ludwig Inst Cancer Res Schwann cell mitogenic factor,its preparation and use
US5770567A (en) * 1994-11-14 1998-06-23 Genentech, Inc. Sensory and motor neuron derived factor (SMDF)
US5721139A (en) * 1995-05-10 1998-02-24 Genentech, Inc. Isolating and culturing schwann cells
US5849585A (en) * 1995-05-10 1998-12-15 Genetech, Inc. Isolating and culturing Schwann cells
US6033660A (en) * 1995-05-10 2000-03-07 Genentech, Inc. Method of treating a nervous system injury with cultured schwann cells
US5912326A (en) * 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
DE69732711T2 (de) * 1996-07-12 2006-03-16 Genentech, Inc., South San Francisco Gamma-heregulin
US6136558A (en) * 1997-02-10 2000-10-24 Genentech, Inc. Heregulin variants
EP0970207B1 (en) 1997-02-10 2009-04-01 Genentech, Inc. Heregulin variants
WO1999031505A1 (en) * 1997-12-15 1999-06-24 Shire Laboratories Inc. Neurotrophic factor assay
US20010023241A1 (en) 1998-02-04 2001-09-20 Sliwkowski Mark X. Use of heregulin as a growth factor
AUPP785098A0 (en) 1998-12-21 1999-01-21 Victor Chang Cardiac Research Institute, The Treatment of heart disease
US6635249B1 (en) 1999-04-23 2003-10-21 Cenes Pharmaceuticals, Inc. Methods for treating congestive heart failure
ITMI20011057A1 (it) * 2001-05-22 2002-11-22 Bracco Imaging Spa Preparazione ed uso di peptidi ciclici e ramificati e loro deriati marcati come agenti terapeutici agonisti o antagonisti della colecistochi
WO2003099320A1 (en) 2002-05-24 2003-12-04 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
US7241392B2 (en) 2004-09-09 2007-07-10 Dresser-Rand Company Rotary separator and method
US20070213264A1 (en) 2005-12-02 2007-09-13 Mingdong Zhou Neuregulin variants and methods of screening and using thereof
EP2918283B1 (en) 2005-12-30 2018-01-31 Zensun (Shanghai) Science & Technology, Co., Ltd. Extended release of neuregulin for improved cardiac function
CN107041949A (zh) 2008-08-15 2017-08-15 阿索尔达治疗公司 在cns神经性损伤后非‑急性期间处理的组合物及方法
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun （Shanghai）Science & Technology Limited Compositions and methods for treating heart failure
KR102357275B1 (ko) 2013-05-22 2022-02-03 젠순 (상하이) 사이언스 앤드 테크놀로지 캄파니 리미티드 심부전을 치료하기 위한 뉴레귤린의 연장 방출

Also Published As

Publication number Publication date
IE921062A1 (en) 1992-10-21
JPH06507544A (ja) 1994-09-01
ZA922441B (en) 1992-11-25
AU1450992A (en) 1992-11-17
GB9107566D0 (en) 1991-05-29
DE69232693T2 (de) 2003-04-03
EP0579640A1 (en) 1994-01-26
AU6808396A (en) 1997-01-16
CA2108119C (en) 2009-06-30
PT100344A (pt) 1993-07-30
WO1992018627A1 (en) 1992-10-29
CA2108119A1 (en) 1992-10-11
AU703772B2 (en) 1999-04-01
DE69232693D1 (de) 2002-08-29
KR100274305B1 (ko) 2000-12-15
PT100344B (pt) 1999-08-31
ATE221083T1 (de) 2002-08-15
EP0579640B1 (en) 2002-07-24

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