DK136651B - Analogifremgangsmåde til fremstilling af pyridinderivater, deres syreadditionssalte eller deres kvaternære ammoniumforbindelser. - Google Patents
Analogifremgangsmåde til fremstilling af pyridinderivater, deres syreadditionssalte eller deres kvaternære ammoniumforbindelser.Info
- Publication number
- DK136651B DK136651B DK55574AA DK55574A DK136651B DK 136651 B DK136651 B DK 136651B DK 55574A A DK55574A A DK 55574AA DK 55574 A DK55574 A DK 55574A DK 136651 B DK136651 B DK 136651B
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- quaternary ammonium
- acid addition
- addition salts
- ammonium compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK466376A DK141703B (da) | 1973-02-01 | 1976-10-15 | Analogifremgangsmåde til fremstilling af pyridiniumderivater. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7303503A FR2215948B1 (zh) | 1973-02-01 | 1973-02-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK136651B true DK136651B (da) | 1977-11-07 |
DK136651C DK136651C (zh) | 1978-04-17 |
Family
ID=9114160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK55574AA DK136651B (da) | 1973-02-01 | 1974-02-01 | Analogifremgangsmåde til fremstilling af pyridinderivater, deres syreadditionssalte eller deres kvaternære ammoniumforbindelser. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4051141A (zh) |
JP (1) | JPS5231357B2 (zh) |
AT (1) | AT338261B (zh) |
AU (1) | AU473141B2 (zh) |
BE (1) | BE809812A (zh) |
CA (1) | CA1038871A (zh) |
CH (1) | CH593287A5 (zh) |
DK (1) | DK136651B (zh) |
ES (2) | ES422581A1 (zh) |
FR (1) | FR2215948B1 (zh) |
GB (1) | GB1445524A (zh) |
IL (3) | IL49786A (zh) |
NL (1) | NL7401237A (zh) |
PH (2) | PH11451A (zh) |
SE (2) | SE416203B (zh) |
ZA (1) | ZA74488B (zh) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2345150A2 (fr) * | 1975-08-06 | 1977-10-21 | Centre Etd Ind Pharma | Nouveaux derives de la thienopyridine, et leur application |
FR2313055A2 (fr) * | 1975-06-05 | 1976-12-31 | Parcor | Nouveaux derives substitues de la thieno-pyridine, leur procede de preparation et leurs applications |
FR2312246A1 (fr) * | 1975-05-28 | 1976-12-24 | Parcor | Derives de la tetrahydro-4,5,6,7 thieno (3,2-c) pyridine, leur procede de preparation et leurs applications |
FR2312247A1 (fr) * | 1975-05-30 | 1976-12-24 | Parcor | Derives de la thieno-pyridine, leur procede de preparation et leurs applications |
FR2315274A1 (fr) * | 1975-06-27 | 1977-01-21 | Parcor | Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications |
US4163852A (en) * | 1975-07-09 | 1979-08-07 | Parcor | Process for the preparation of tetrahydro-thieno[3,2-c]- and [2,3-c]pyridine derivatives |
JPS5283950A (en) * | 1976-01-02 | 1977-07-13 | Sentore Deechiyuude Puuru Rand | Medicine for disease derived from blood magma |
FR2338703A1 (fr) * | 1976-01-22 | 1977-08-19 | Parcor | Derives de thieno (3,2-c) pyridine, leur procede de preparation et leurs applications |
FR2376860A1 (fr) * | 1977-01-07 | 1978-08-04 | Parcor | Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique |
GB2038625B (en) * | 1978-12-29 | 1983-01-12 | Parcor | Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity |
FR2395028A2 (fr) * | 1977-06-22 | 1979-01-19 | Centre Etd Ind Pharma | Derives pyridiniques, leur preparation et leurs application therapeutique |
US4464377A (en) * | 1977-06-22 | 1984-08-07 | BLANCHARD Jean | Anti-thrombotic therapeutic compositions |
GB2038178B (en) * | 1978-12-29 | 1983-03-09 | Parcor | Antithrombotic therapeutic compsition |
FR2397417A1 (fr) * | 1977-07-12 | 1979-02-09 | Parcor | Procede de preparation de derives de la thienopyridine |
JPS5498337A (en) * | 1978-01-06 | 1979-08-03 | Dai Ichi Seiyaku Co Ltd | Anticarcinogenic and/or antimetastatic agent |
JPS54105236A (en) * | 1978-02-06 | 1979-08-18 | Dai Ichi Seiyaku Co Ltd | Antithrombogenetic agent for shunt and/or artificial blood vessel |
US4490377A (en) * | 1980-07-29 | 1984-12-25 | Syntex (U.S.A.) Inc. | Acid stabilized compositions of thieno-pyridine derived compounds |
US4321266A (en) * | 1980-10-06 | 1982-03-23 | Sanofi | 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine |
US4400384A (en) * | 1980-10-06 | 1983-08-23 | Sanofi, S.A. | 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-c] pyridine methanesulfonate and other novel salts thereof |
FR2495157A1 (fr) * | 1980-11-28 | 1982-06-04 | Sanofi Sa | Procede nouveau de preparation des tetrahydro-5, 6, 7, 7a 4h-thieno (3, 2-c) pyridinones-2 |
FR2495158A1 (fr) * | 1980-11-28 | 1982-06-04 | Sanofi Sa | Nouveau procede de preparation de derives de la tetrahydro-5, 6, 7, 7a 4h-thieno (3, 2-c) pyridinone-2 |
FR2495156A1 (fr) * | 1980-11-28 | 1982-06-04 | Sanofi Sa | Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique |
FR2508442A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation d'ethylamines b-cyclo-substituees et produits ainsi obtenus |
FR2530247B1 (fr) * | 1982-07-13 | 1986-05-16 | Sanofi Sa | Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique |
IT8222600A0 (it) * | 1982-07-28 | 1982-07-28 | Pietro Tommaso Tessitore | Nuovi idrossibenzensolfonati della 5-(o-clorobenzil)-4,5,6,7-tetraidro tieno parentesi quadra aperta 3,2-c parentesi quadra chiusa piridina. |
JPS6044344U (ja) * | 1983-09-03 | 1985-03-28 | オムロン株式会社 | リレ−の駆動回路 |
FR2566775B1 (fr) * | 1984-06-27 | 1986-10-31 | Synthelabo | Derives de tetrahydro-4,5,6,7 furo ou 1h-pyrrolo(2,3-c)pyridine, leur preparation et leur application en therapeutique |
FR2570701B1 (fr) * | 1984-09-27 | 1987-05-22 | Synthelabo | Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique |
JPS6185391A (ja) * | 1984-10-03 | 1986-04-30 | Nisshin Flour Milling Co Ltd | 5−(2−クロロベンジル)−4,5,6,7−テトラヒドロチエノ〔3,2−c〕ピリジンの製造方法 |
GB8429087D0 (en) * | 1984-11-16 | 1984-12-27 | Scras | Thienopyridine derivatives |
FR2612777A1 (fr) * | 1987-03-26 | 1988-09-30 | Inst Nat Sante Rech Med | Composition medicamenteuse pour le traitement et la prevention de maladies dues a une cytotoxicite a mediation cellulaire, renfermant au moins un derive de la pyridine comme principe actif |
US4906756A (en) * | 1988-05-10 | 1990-03-06 | Syntex (U.S.A.) Inc. | 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives |
US4879313A (en) * | 1988-07-20 | 1989-11-07 | Mosanto Company | Novel platelet-aggregation inhibitors |
US5037808A (en) * | 1988-07-20 | 1991-08-06 | Monsanto Co. | Indolyl platelet-aggregation inhibitors |
US5053393A (en) * | 1988-07-20 | 1991-10-01 | Monsanto Company | Novel platelet-aggregation inhibitor |
US4992463A (en) * | 1988-07-20 | 1991-02-12 | Monsanto Company | Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation |
JPH02145581A (ja) * | 1988-10-11 | 1990-06-05 | Lonza Ag | 置換チエニルエチルアミンとその製造方法 |
GB8824400D0 (en) * | 1988-10-18 | 1988-11-23 | Glaxo Group Ltd | Chemical compounds |
US4997945A (en) * | 1990-01-25 | 1991-03-05 | Syntex (U.S.A.) Inc. | Carbamate salts of 2-(2'-thienyl)alkylamines |
FI101150B (fi) * | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
JP2712144B2 (ja) * | 1992-02-06 | 1998-02-10 | 田辺製薬株式会社 | 血小板凝集抑制組成物 |
US5296603A (en) * | 1992-06-08 | 1994-03-22 | Fuji Photo Film Co., Ltd. | 3-amino-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine-2-carboxylic acid compounds |
US5294621A (en) * | 1992-10-07 | 1994-03-15 | Ortho Pharmaceutical Corporation | Thieno tetrahydropyridines useful as class III antiarrhythmic agents |
NZ334389A (en) * | 1996-08-28 | 2001-05-25 | Ube Industries | Cyclic amine derivatives |
US6043368A (en) * | 1996-09-04 | 2000-03-28 | Poli Industria Chimica, S.P.A. | Method of making thieno-pyridine derivatives |
US5872128A (en) * | 1997-10-15 | 1999-02-16 | Invamed, Inc. | Stabilized composition of ticlopidine hydrochloride |
KR100567950B1 (ko) | 1998-02-27 | 2006-04-05 | 상꾜 가부시키가이샤 | 환상 아미노화합물 |
US20080113025A1 (en) * | 1998-11-02 | 2008-05-15 | Elan Pharma International Limited | Compositions comprising nanoparticulate naproxen and controlled release hydrocodone |
US20090297597A1 (en) * | 1998-11-02 | 2009-12-03 | Gary Liversidge | Modified Release Ticlopidine Compositions |
RU2270695C2 (ru) | 1999-03-17 | 2006-02-27 | Дайити Фармасьютикал Ко., Лтд. | Фармацевтическая композиция |
EP1350511B1 (en) | 2000-12-25 | 2008-09-10 | Daiichi Sankyo Company, Limited | Medicinal compositions containing aspirin |
US6495691B1 (en) | 2001-07-06 | 2002-12-17 | Brantford Chemicals Inc. | Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives |
US20050192245A1 (en) * | 2002-07-18 | 2005-09-01 | Sankyo Company, Limited | Medicinal composition for treating arteriosclerosis |
CA2454015C (en) * | 2003-12-23 | 2009-11-24 | Brantford Chemicals Inc. | A process for the preparation of tetrahydrothieno [3,2-c] pyridine derivatives |
DE112006001548T5 (de) * | 2005-06-12 | 2008-04-30 | Elan Corp. Plc | Ticlopidin-Zusammensetzungen mit modifizierter Freisetzung |
WO2008060934A2 (en) * | 2006-11-14 | 2008-05-22 | Acusphere, Inc. | Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration |
EP1980563A1 (en) | 2007-04-09 | 2008-10-15 | BATTULA, Srinivasa Reddy | Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate |
US20100297621A1 (en) * | 2007-06-20 | 2010-11-25 | University Of Utah Research Foundation | Use of pre-mrna splicing in platelet cells for the diagnosis of disease |
CN102241690B (zh) | 2010-05-13 | 2015-08-12 | 天津药物研究院 | 一类含腈基的噻吩并吡啶酯类衍生物、其制备方法和用途 |
DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
EP4070658A1 (de) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Verwendung von blutgerinnungshemmenden verbindungen als rodentizide |
-
1973
- 1973-02-01 FR FR7303503A patent/FR2215948B1/fr not_active Expired
-
1974
- 1974-01-15 CH CH49874A patent/CH593287A5/xx active Protection Beyond IP Right Term
- 1974-01-16 BE BE139867A patent/BE809812A/xx not_active IP Right Cessation
- 1974-01-22 IL IL49786A patent/IL49786A/en unknown
- 1974-01-22 IL IL44061A patent/IL44061A/en unknown
- 1974-01-23 ZA ZA740488A patent/ZA74488B/xx unknown
- 1974-01-24 ES ES422581A patent/ES422581A1/es not_active Expired
- 1974-01-28 SE SE7401036A patent/SE416203B/xx active Protection Beyond IP Right Term
- 1974-01-28 AT AT67874A patent/AT338261B/de not_active IP Right Cessation
- 1974-01-29 PH PH15449A patent/PH11451A/en unknown
- 1974-01-29 NL NL7401237A patent/NL7401237A/xx unknown
- 1974-01-30 GB GB439274A patent/GB1445524A/en not_active Expired
- 1974-01-30 AU AU65010/74A patent/AU473141B2/en not_active Expired
- 1974-01-31 CA CA191,469A patent/CA1038871A/en not_active Expired
- 1974-01-31 JP JP49013559A patent/JPS5231357B2/ja not_active Expired
- 1974-02-01 DK DK55574AA patent/DK136651B/da not_active IP Right Cessation
-
1976
- 1976-02-20 US US05/660,248 patent/US4051141A/en not_active Expired - Lifetime
- 1976-03-02 ES ES445702A patent/ES445702A1/es not_active Expired
- 1976-04-30 PH PH18386A patent/PH11759A/en unknown
- 1976-06-14 IL IL49786A patent/IL49786A0/xx unknown
-
1977
- 1977-03-17 SE SE7703028A patent/SE421624B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA1038871A (en) | 1978-09-19 |
BE809812A (fr) | 1974-07-16 |
FR2215948B1 (zh) | 1976-05-14 |
PH11759A (en) | 1978-06-27 |
DE2404308A1 (de) | 1974-08-08 |
IL44061A0 (en) | 1974-05-16 |
SE416203B (sv) | 1980-12-08 |
DE2404308B2 (de) | 1977-06-30 |
ATA67874A (de) | 1976-12-15 |
AU6501074A (en) | 1975-07-31 |
JPS5046688A (zh) | 1975-04-25 |
PH11451A (en) | 1978-02-01 |
CH593287A5 (zh) | 1977-11-30 |
ZA74488B (en) | 1974-11-27 |
SE421624B (sv) | 1982-01-18 |
AU473141B2 (en) | 1976-06-17 |
FR2215948A1 (zh) | 1974-08-30 |
US4051141A (en) | 1977-09-27 |
IL49786A (en) | 1977-06-30 |
ES422581A1 (es) | 1976-10-01 |
IL49786A0 (en) | 1976-08-31 |
SE7703028L (sv) | 1977-03-17 |
NL7401237A (zh) | 1974-08-05 |
IL44061A (en) | 1977-06-30 |
ES445702A1 (es) | 1977-06-01 |
JPS5231357B2 (zh) | 1977-08-13 |
AT338261B (de) | 1977-08-10 |
DK136651C (zh) | 1978-04-17 |
GB1445524A (en) | 1976-08-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |