DK134032B - Fremgangsmåde til fremstilling af en levedygtig stabil virussuspension. - Google Patents

Fremgangsmåde til fremstilling af en levedygtig stabil virussuspension.

Info

Publication number
DK134032B
DK134032B DK64774A DK64774A DK134032B DK 134032 B DK134032 B DK 134032B DK 64774 A DK64774 A DK 64774A DK 64774 A DK64774 A DK 64774A DK 134032 B DK134032 B DK 134032B
Authority
DK
Denmark
Prior art keywords
producing
virus suspension
stable virus
viable
viable stable
Prior art date
Application number
DK64774A
Other languages
Danish (da)
English (en)
Other versions
DK134032C (enExample
Inventor
Nathan Zygraich
Julien Peetermans
Original Assignee
Rit Rech Ind Therapeut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rit Rech Ind Therapeut filed Critical Rit Rech Ind Therapeut
Publication of DK134032B publication Critical patent/DK134032B/da
Application granted granted Critical
Publication of DK134032C publication Critical patent/DK134032C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16351Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16751Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK64774A 1973-02-09 1974-02-06 Fremgangsmåde til fremstilling af en levedygtig stabil virussuspension. DK134032B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US330912A US3915794A (en) 1973-02-09 1973-02-09 Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them

Publications (2)

Publication Number Publication Date
DK134032B true DK134032B (da) 1976-08-30
DK134032C DK134032C (enExample) 1977-02-07

Family

ID=23291840

Family Applications (1)

Application Number Title Priority Date Filing Date
DK64774A DK134032B (da) 1973-02-09 1974-02-06 Fremgangsmåde til fremstilling af en levedygtig stabil virussuspension.

Country Status (18)

Country Link
US (1) US3915794A (enExample)
JP (1) JPS5732043B2 (enExample)
AT (1) AT331398B (enExample)
BE (1) BE810555A (enExample)
CA (1) CA1035700A (enExample)
CH (1) CH592143A5 (enExample)
DD (1) DD110306A5 (enExample)
DE (1) DE2406167C2 (enExample)
DK (1) DK134032B (enExample)
ES (1) ES422961A1 (enExample)
FR (1) FR2216997B1 (enExample)
GB (1) GB1452344A (enExample)
HU (1) HU169120B (enExample)
IE (1) IE38825B1 (enExample)
IL (1) IL44011A (enExample)
NL (1) NL178013C (enExample)
SE (1) SE427799B (enExample)
ZA (1) ZA74163B (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57114527A (en) * 1979-10-29 1982-07-16 Merck & Co Inc Vaccine stabilizer
PT71926B (en) * 1979-10-29 1982-03-31 Merck & Co Inc Process for preparing a liquid vaccine comprising a stabilizer
US4273762A (en) * 1979-12-03 1981-06-16 Merck & Co., Inc. Lyophilization process for live viral compositions
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
ZA874625B (en) * 1986-06-30 1988-10-26 Smith Kline Rit Stabilizers for live vaccines,process for their preparation and vaccines containing them
US4847078A (en) * 1987-01-14 1989-07-11 Arseco, Inc. Storage stable topical composition having moisture control agent
JPH01112853U (enExample) * 1988-01-27 1989-07-28
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
EP0484519A4 (en) * 1990-05-25 1993-12-29 Cryopharm Corporation Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatible amphipathic polymers
AU2088992A (en) * 1992-05-05 1993-11-11 Research Foundation For Microbial Diseases Of Osaka University, The Stabilized live vaccine
CZ289574B6 (cs) * 1992-06-04 2002-02-13 Merck And Co., Inc. Způsob výroby ľivé, atenuované vakcíny viru varicella zoster
US5360736A (en) * 1992-06-04 1994-11-01 Merck & Co., Inc. Process for attenuated varicella zoster virus vaccine production
CA2158935A1 (en) * 1993-10-12 1995-04-20 Chiron Viagene, Inc. Methods for preserving recombinant viruses
DE69732029T2 (de) * 1996-04-26 2006-02-23 Merck & Co., Inc. Dna enthaltende impfstoffen
ZA973642B (en) * 1996-04-26 1997-11-25 Merck & Co Inc DNA vaccine formulations.
US6051238A (en) * 1996-12-20 2000-04-18 Merck & Co., Inc. Stabilizers for lyophilized mumps vaccines
US6210683B1 (en) 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
US6926897B1 (en) * 1998-03-24 2005-08-09 Medigene Aktiengesellschaft Medicament for the avoidance or treatment of papillomavirus-specific tumour
DE19812940A1 (de) * 1998-03-24 1999-10-07 Medigene Ag Formulierung mit Papillomavirus-spezifischem Protein, seine Herstellung und Verwendung
GB9808922D0 (en) * 1998-04-24 1998-06-24 Cantab Pharmaceuticals Res Ltd Virus preparations
US6225289B1 (en) 1998-12-10 2001-05-01 Genvec, Inc. Methods and compositions for preserving adenoviral vectors
RU2144376C1 (ru) * 1999-06-28 2000-01-20 Всероссийский научно-исследовательский институт защиты животных Сухая вирусвакцина против болезни марека и способ ее изготовления
RU2144378C1 (ru) * 1999-06-28 2000-01-20 Всероссийский научно-исследовательский институт защиты животных Вирусвакцина против болезни марека и способ ее изготовления
FR2814957B1 (fr) * 2000-10-06 2002-12-20 Aventis Pasteur Composition vaccinale et procede de stabilisation
US7013940B2 (en) * 2001-04-19 2006-03-21 Michelin Recherche Et Technique S.A. Device for attenuating cavity noise in a tire and wheel
NZ533302A (en) * 2001-12-10 2005-11-25 Bavarian Nordic As Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions containing a disaaccharide and a pharmaceutically acceptable polymer i.e. dextran or polyvinylpyrrolidon (PVP)
TWI398272B (zh) * 2005-03-08 2013-06-11 Intervet Int Bv 化學定義的安定劑
EP1870649A1 (en) 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
CA2844927C (en) 2011-08-12 2017-10-31 Merial Limited Vacuum-assisted preservation of biological products, in particular of vaccines
TWI690322B (zh) * 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
EP3142486B1 (en) 2014-05-14 2026-03-11 Boehringer Ingelheim Vetmedica GmbH Methods for freeze-drying and rehydrating biologics
DK3226894T3 (da) * 2014-12-01 2019-10-21 Transgene Sa Stabile flydende vacciniavirus-formuleringer
CN105999287A (zh) * 2016-07-01 2016-10-12 广东圣戈生物科技有限公司 一种疫苗稀释液及其制备方法
MX2019003947A (es) 2016-10-05 2019-06-10 Zoetis Services Llc Metodos de liofilizacion que proporcionan protozoos deshidratados de forma estable para uso como potentes vacunas vivas.
US20200308550A1 (en) 2017-09-11 2020-10-01 Imba - Institut Für Molekulare Biotechnologie Gmbh Tumor organoid model

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1292803A (en) * 1968-11-18 1972-10-11 Nat Res Dev Improvements relating to the production of antigens
US3642574A (en) * 1970-04-29 1972-02-15 Us Agriculture Method for producing vaccine for immunization of poultry against marek{3 s disease
US3783098A (en) * 1971-08-10 1974-01-01 Cornell Res Foundation Inc Highly potent,viable and stable cellfree virus preparations from cells infected with cell-associated viruses and method for obtaining the same

Also Published As

Publication number Publication date
HU169120B (enExample) 1976-09-28
IL44011A0 (en) 1974-05-16
AT331398B (de) 1976-08-25
DE2406167C2 (de) 1984-12-20
DE2406167A1 (de) 1974-08-15
CH592143A5 (enExample) 1977-10-14
NL178013B (nl) 1985-08-01
FR2216997A1 (enExample) 1974-09-06
US3915794A (en) 1975-10-28
BE810555A (fr) 1974-08-05
ATA98274A (de) 1975-11-15
DK134032C (enExample) 1977-02-07
NL178013C (nl) 1986-01-02
JPS5732043B2 (enExample) 1982-07-08
CA1035700A (en) 1978-08-01
GB1452344A (en) 1976-10-13
IE38825B1 (en) 1978-06-07
JPS49109518A (enExample) 1974-10-18
SE427799B (sv) 1983-05-09
ZA74163B (en) 1974-11-27
IL44011A (en) 1977-04-29
NL7401786A (enExample) 1974-08-13
IE38825L (en) 1974-08-09
ES422961A1 (es) 1976-06-01
AU6486574A (en) 1975-07-24
DD110306A5 (enExample) 1974-12-12
FR2216997B1 (enExample) 1978-01-06

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