DK1335927T3 - Fremgangsmåde til syntese af optisk aktive anthracycliner - Google Patents
Fremgangsmåde til syntese af optisk aktive anthracyclinerInfo
- Publication number
- DK1335927T3 DK1335927T3 DK01982487T DK01982487T DK1335927T3 DK 1335927 T3 DK1335927 T3 DK 1335927T3 DK 01982487 T DK01982487 T DK 01982487T DK 01982487 T DK01982487 T DK 01982487T DK 1335927 T3 DK1335927 T3 DK 1335927T3
- Authority
- DK
- Denmark
- Prior art keywords
- synthesis
- optically active
- anthracyclines
- active anthracyclines
- dehydrochloridation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Input From Keyboards Or The Like (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000FI000237A IT1317106B1 (it) | 2000-11-16 | 2000-11-16 | Processo per la sintesi di antracicline otticamente attive. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1335927T3 true DK1335927T3 (da) | 2006-11-20 |
Family
ID=11441998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01982487T DK1335927T3 (da) | 2000-11-16 | 2001-11-15 | Fremgangsmåde til syntese af optisk aktive anthracycliner |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6921841B2 (el) |
| EP (1) | EP1335927B1 (el) |
| JP (1) | JP4359043B2 (el) |
| KR (1) | KR100821795B1 (el) |
| CN (1) | CN1249071C (el) |
| AT (1) | ATE333460T1 (el) |
| AU (1) | AU2002214054A1 (el) |
| BR (1) | BRPI0115250B8 (el) |
| CA (1) | CA2429136C (el) |
| CY (1) | CY1106182T1 (el) |
| DE (1) | DE60121615T2 (el) |
| DK (1) | DK1335927T3 (el) |
| EE (1) | EE05155B1 (el) |
| ES (1) | ES2267834T3 (el) |
| IT (1) | IT1317106B1 (el) |
| MX (1) | MXPA03004188A (el) |
| PL (1) | PL212720B1 (el) |
| PT (1) | PT1335927E (el) |
| RS (1) | RS50465B (el) |
| RU (1) | RU2286994C2 (el) |
| WO (1) | WO2002040496A1 (el) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1500421A (en) | 1975-01-22 | 1978-02-08 | Farmaceutici Italia | Optically active anthracyclinones |
| US4116981A (en) | 1977-05-02 | 1978-09-26 | Yuh-Geng Tsay | 5,12-epoxy-naphthacene-6,11-dione derivatives |
| US4405713A (en) * | 1981-12-28 | 1983-09-20 | Hoffmann-La Roche Inc. | Process for the preparation of optically active anthracycline glycosides A and B |
| JPS62132838A (ja) * | 1985-12-03 | 1987-06-16 | Sumitomo Pharmaceut Co Ltd | テトラヒドロナフタセン誘導体の製造法 |
-
2000
- 2000-11-16 IT IT2000FI000237A patent/IT1317106B1/it active
-
2001
- 2001-11-15 MX MXPA03004188A patent/MXPA03004188A/es active IP Right Grant
- 2001-11-15 EP EP01982487A patent/EP1335927B1/en not_active Expired - Lifetime
- 2001-11-15 AU AU2002214054A patent/AU2002214054A1/en not_active Abandoned
- 2001-11-15 AT AT01982487T patent/ATE333460T1/de active
- 2001-11-15 DE DE60121615T patent/DE60121615T2/de not_active Expired - Lifetime
- 2001-11-15 BR BRPI0115250A patent/BRPI0115250B8/pt not_active IP Right Cessation
- 2001-11-15 CN CNB018190383A patent/CN1249071C/zh not_active Expired - Lifetime
- 2001-11-15 EE EEP200300180A patent/EE05155B1/xx unknown
- 2001-11-15 ES ES01982487T patent/ES2267834T3/es not_active Expired - Lifetime
- 2001-11-15 JP JP2002543504A patent/JP4359043B2/ja not_active Expired - Fee Related
- 2001-11-15 RU RU2003117429/04A patent/RU2286994C2/ru active
- 2001-11-15 KR KR1020037006637A patent/KR100821795B1/ko active IP Right Grant
- 2001-11-15 DK DK01982487T patent/DK1335927T3/da active
- 2001-11-15 PT PT01982487T patent/PT1335927E/pt unknown
- 2001-11-15 RS YUP-373/03A patent/RS50465B/sr unknown
- 2001-11-15 CA CA2429136A patent/CA2429136C/en not_active Expired - Lifetime
- 2001-11-15 US US10/416,649 patent/US6921841B2/en not_active Expired - Lifetime
- 2001-11-15 WO PCT/EP2001/013217 patent/WO2002040496A1/en active IP Right Grant
- 2001-11-15 PL PL361618A patent/PL212720B1/pl unknown
-
2006
- 2006-09-29 CY CY20061101418T patent/CY1106182T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1249071C (zh) | 2006-04-05 |
| KR100821795B1 (ko) | 2008-04-11 |
| MXPA03004188A (es) | 2003-09-22 |
| ATE333460T1 (de) | 2006-08-15 |
| EE05155B1 (et) | 2009-04-15 |
| BR0115250B1 (pt) | 2015-01-06 |
| CY1106182T1 (el) | 2011-06-08 |
| CA2429136C (en) | 2011-03-29 |
| AU2002214054A1 (en) | 2002-05-27 |
| IT1317106B1 (it) | 2003-05-26 |
| KR20030055306A (ko) | 2003-07-02 |
| PL361618A1 (en) | 2004-10-04 |
| EE200300180A (et) | 2003-06-16 |
| ES2267834T3 (es) | 2007-03-16 |
| PL212720B1 (pl) | 2012-11-30 |
| BR0115250A (pt) | 2003-08-12 |
| JP2004513952A (ja) | 2004-05-13 |
| DE60121615T2 (de) | 2007-08-09 |
| JP4359043B2 (ja) | 2009-11-04 |
| WO2002040496A1 (en) | 2002-05-23 |
| EP1335927A1 (en) | 2003-08-20 |
| DE60121615D1 (de) | 2006-08-31 |
| RU2286994C2 (ru) | 2006-11-10 |
| EP1335927B1 (en) | 2006-07-19 |
| CA2429136A1 (en) | 2002-05-23 |
| BRPI0115250B8 (pt) | 2021-05-25 |
| US6921841B2 (en) | 2005-07-26 |
| US20040029819A1 (en) | 2004-02-12 |
| CN1474827A (zh) | 2004-02-11 |
| ITFI20000237A1 (it) | 2002-05-16 |
| PT1335927E (pt) | 2006-11-30 |
| YU37303A (sh) | 2006-05-25 |
| RS50465B (sr) | 2010-03-02 |
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