ATE333460T1 - Prozess zur herstellung optisch aktiver anthracycline - Google Patents

Prozess zur herstellung optisch aktiver anthracycline

Info

Publication number
ATE333460T1
ATE333460T1 AT01982487T AT01982487T ATE333460T1 AT E333460 T1 ATE333460 T1 AT E333460T1 AT 01982487 T AT01982487 T AT 01982487T AT 01982487 T AT01982487 T AT 01982487T AT E333460 T1 ATE333460 T1 AT E333460T1
Authority
AT
Austria
Prior art keywords
optically active
producing optically
anthracyclines
active anthracyclines
dehydrochloridation
Prior art date
Application number
AT01982487T
Other languages
English (en)
Inventor
Bugno Cristina Di
Arata Fabio D
Alessio Ramacciotti
Paolo Crotti
Original Assignee
Menarini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche Spa filed Critical Menarini Ricerche Spa
Application granted granted Critical
Publication of ATE333460T1 publication Critical patent/ATE333460T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Input From Keyboards Or The Like (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT01982487T 2000-11-16 2001-11-15 Prozess zur herstellung optisch aktiver anthracycline ATE333460T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000FI000237A IT1317106B1 (it) 2000-11-16 2000-11-16 Processo per la sintesi di antracicline otticamente attive.

Publications (1)

Publication Number Publication Date
ATE333460T1 true ATE333460T1 (de) 2006-08-15

Family

ID=11441998

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01982487T ATE333460T1 (de) 2000-11-16 2001-11-15 Prozess zur herstellung optisch aktiver anthracycline

Country Status (21)

Country Link
US (1) US6921841B2 (de)
EP (1) EP1335927B1 (de)
JP (1) JP4359043B2 (de)
KR (1) KR100821795B1 (de)
CN (1) CN1249071C (de)
AT (1) ATE333460T1 (de)
AU (1) AU2002214054A1 (de)
BR (1) BRPI0115250B8 (de)
CA (1) CA2429136C (de)
CY (1) CY1106182T1 (de)
DE (1) DE60121615T2 (de)
DK (1) DK1335927T3 (de)
EE (1) EE05155B1 (de)
ES (1) ES2267834T3 (de)
IT (1) IT1317106B1 (de)
MX (1) MXPA03004188A (de)
PL (1) PL212720B1 (de)
PT (1) PT1335927E (de)
RS (1) RS50465B (de)
RU (1) RU2286994C2 (de)
WO (1) WO2002040496A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1500421A (en) 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4116981A (en) 1977-05-02 1978-09-26 Yuh-Geng Tsay 5,12-epoxy-naphthacene-6,11-dione derivatives
US4405713A (en) * 1981-12-28 1983-09-20 Hoffmann-La Roche Inc. Process for the preparation of optically active anthracycline glycosides A and B
JPS62132838A (ja) * 1985-12-03 1987-06-16 Sumitomo Pharmaceut Co Ltd テトラヒドロナフタセン誘導体の製造法

Also Published As

Publication number Publication date
CN1249071C (zh) 2006-04-05
KR100821795B1 (ko) 2008-04-11
MXPA03004188A (es) 2003-09-22
EE05155B1 (et) 2009-04-15
BR0115250B1 (pt) 2015-01-06
CY1106182T1 (el) 2011-06-08
CA2429136C (en) 2011-03-29
AU2002214054A1 (en) 2002-05-27
IT1317106B1 (it) 2003-05-26
KR20030055306A (ko) 2003-07-02
PL361618A1 (en) 2004-10-04
EE200300180A (et) 2003-06-16
ES2267834T3 (es) 2007-03-16
PL212720B1 (pl) 2012-11-30
BR0115250A (pt) 2003-08-12
JP2004513952A (ja) 2004-05-13
DE60121615T2 (de) 2007-08-09
JP4359043B2 (ja) 2009-11-04
WO2002040496A1 (en) 2002-05-23
EP1335927A1 (de) 2003-08-20
DE60121615D1 (de) 2006-08-31
RU2286994C2 (ru) 2006-11-10
EP1335927B1 (de) 2006-07-19
CA2429136A1 (en) 2002-05-23
BRPI0115250B8 (pt) 2021-05-25
US6921841B2 (en) 2005-07-26
US20040029819A1 (en) 2004-02-12
CN1474827A (zh) 2004-02-11
DK1335927T3 (da) 2006-11-20
ITFI20000237A1 (it) 2002-05-16
PT1335927E (pt) 2006-11-30
YU37303A (sh) 2006-05-25
RS50465B (sr) 2010-03-02

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