DK1325340T3 - Identifikation af proteinbindingssteder - Google Patents

Identifikation af proteinbindingssteder

Info

Publication number
DK1325340T3
DK1325340T3 DK01979110T DK01979110T DK1325340T3 DK 1325340 T3 DK1325340 T3 DK 1325340T3 DK 01979110 T DK01979110 T DK 01979110T DK 01979110 T DK01979110 T DK 01979110T DK 1325340 T3 DK1325340 T3 DK 1325340T3
Authority
DK
Denmark
Prior art keywords
segment
protein
nucleic acid
discontinuous
identification
Prior art date
Application number
DK01979110T
Other languages
Danish (da)
English (en)
Inventor
Jelle Wouter Slootstra
Wouter Cornelis Puijk
Robert Hans Meloen
Dijk Evert Van
Dijken Pieter Van
Original Assignee
Pepscan Systems Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pepscan Systems Bv filed Critical Pepscan Systems Bv
Application granted granted Critical
Publication of DK1325340T3 publication Critical patent/DK1325340T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK01979110T 2000-10-11 2001-10-10 Identifikation af proteinbindingssteder DK1325340T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00203518A EP1197755A1 (fr) 2000-10-11 2000-10-11 Identification de sites de liaison de protéines
PCT/NL2001/000744 WO2002031510A1 (fr) 2000-10-11 2001-10-10 Identification de sites de liaison de proteines

Publications (1)

Publication Number Publication Date
DK1325340T3 true DK1325340T3 (da) 2009-02-16

Family

ID=8172123

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01979110T DK1325340T3 (da) 2000-10-11 2001-10-10 Identifikation af proteinbindingssteder

Country Status (14)

Country Link
US (2) US7972993B2 (fr)
EP (2) EP1197755A1 (fr)
JP (2) JP2004511780A (fr)
AT (1) ATE411526T1 (fr)
AU (2) AU2002211099B2 (fr)
CA (1) CA2424611C (fr)
CY (1) CY1110101T1 (fr)
DE (1) DE60136202D1 (fr)
DK (1) DK1325340T3 (fr)
ES (1) ES2317941T3 (fr)
IL (2) IL155277A0 (fr)
NZ (1) NZ524874A (fr)
PT (1) PT1325340E (fr)
WO (1) WO2002031510A1 (fr)

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US7736909B2 (en) 2003-01-09 2010-06-15 Board Of Regents, The University Of Texas System Methods and compositions comprising capture agents
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US7884052B2 (en) * 2004-09-03 2011-02-08 Receptors Llc Combinatorial artificial receptors including tether building blocks on scaffolds
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CA2764153C (fr) 2009-06-02 2021-07-27 The Board Of Regents Of The University Of Texas System Identification de petites molecules reconnues par des anticorps chez des sujets atteints de maladies neurodegeneratives
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WO2012139137A2 (fr) 2011-04-08 2012-10-11 Tufts Medical Center, Inc. Conception et utilisation de pepducine
AU2012340623A1 (en) 2011-11-23 2014-07-17 Igenica Biotherapeutics, Inc. Anti-CD98 antibodies and methods of use thereof
EP2812344A4 (fr) 2012-02-07 2015-10-28 Vibrant Holdings Llc Substrats, réseaux de peptides et procédés
US10006909B2 (en) 2012-09-28 2018-06-26 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
AU2013329311A1 (en) 2012-10-09 2015-04-30 Igenica Biotherapeutics, Inc. Anti-C16orf54 antibodies and methods of use thereof
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
JP5981667B2 (ja) 2013-02-15 2016-08-31 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー 増幅された電気化学発光検出のための方法および組成物
EP2767549A1 (fr) 2013-02-19 2014-08-20 Adienne S.A. Anticorps anti-CD26 et leurs utilisations
WO2015097077A2 (fr) 2013-12-27 2015-07-02 F. Hoffmann-La Roche Ag Découverte systémique, maturation et extension de peptides de liaison aux protéines
SG11201606018UA (en) 2014-01-24 2016-08-30 Ngm Biopharmaceuticals Inc Binding proteins and methods of use thereof
WO2015166036A1 (fr) 2014-05-02 2015-11-05 Morphosys Ag Banques de peptides
US10900964B2 (en) 2014-09-10 2021-01-26 Vibrant Holdings, Llc Peptide microarrays and novel biomarkers for celiac disease
AU2016251501A1 (en) 2015-04-20 2017-10-19 F. Hoffmann-La Roche Ag Specific peptide binders to proteins identified via systemic discovery, maturation and extension process
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WO2016208696A1 (fr) 2015-06-24 2016-12-29 Ｊｃｒファーマ株式会社 Protéine hybride contenant un bdnf
CN107949573B (zh) 2015-09-01 2022-05-03 艾吉纳斯公司 抗-pd-1抗体及其使用方法
WO2017083618A1 (fr) 2015-11-13 2017-05-18 Oasis Pharmaceuticals, LLC Modulateurs du récepteur activé par protéase de type 2
JP7267012B2 (ja) 2016-05-27 2023-05-01 アジェナス インコーポレイテッド 抗ｔｉｍ－３抗体及びその使用方法
US10844119B2 (en) 2016-10-11 2020-11-24 Agenus Inc. Anti-LAG-3 antibodies and methods of use thereof
ES2963226T3 (es) 2016-12-07 2024-03-26 Agenus Inc Anticuerpos ANTI-CTLA-4 y métodos de uso de los mismos
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MX2019012223A (es) 2017-04-13 2019-12-09 Agenus Inc Anticuerpos anti-cd137 y metodos de uso de los mismos.
US11021537B2 (en) 2017-05-01 2021-06-01 Agenus Inc. Anti-TIGIT antibodies and methods of use thereof
US10538808B2 (en) 2017-05-26 2020-01-21 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
EP3652209A2 (fr) 2017-07-11 2020-05-20 Compass Therapeutics LLC Anticorps agonistes qui lient cd137 humain et leurs utilisations
US11718679B2 (en) 2017-10-31 2023-08-08 Compass Therapeutics Llc CD137 antibodies and PD-1 antagonists and uses thereof
EP3713961A2 (fr) 2017-11-20 2020-09-30 Compass Therapeutics LLC Anticorps cd137 et anticorps ciblant un antigène tumoral et leurs utilisations
WO2020033925A2 (fr) 2018-08-09 2020-02-13 Compass Therapeutics Llc Anticorps qui se lient à cd277 et leurs utilisations
JP7497351B2 (ja) 2018-11-13 2024-06-10 コンパス セラピューティクス リミテッド ライアビリティ カンパニー チェックポイント分子に対する多重特異性結合性構築物およびその使用
EP3911679A1 (fr) 2019-01-16 2021-11-24 Compass Therapeutics LLC Formulations d'anticorps qui se lient au cd137 humain et leurs utilisations
TW202122420A (zh) 2019-08-30 2021-06-16 美商艾吉納斯公司 抗ｃｄ９６抗體及其使用方法
US11459389B2 (en) 2019-10-24 2022-10-04 Massachusetts Institute Of Technology Monoclonal antibodies that bind human CD161
RU2743316C1 (ru) * 2020-08-14 2021-02-17 Автономная некоммерческая образовательная организация высшего образования Сколковский институт науки и технологий Способ идентификации участков связывания белковых комплексов
MX2024002281A (es) 2021-08-23 2024-05-20 Immunitas Therapeutics Inc Anticuerpos anti-cd161 y usos de los mismos.

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Also Published As

Publication number Publication date
CA2424611C (fr) 2011-01-25
CA2424611A1 (fr) 2002-04-18
US20030228605A1 (en) 2003-12-11
WO2002031510A1 (fr) 2002-04-18
ATE411526T1 (de) 2008-10-15
DE60136202D1 (de) 2008-11-27
US7972993B2 (en) 2011-07-05
IL155277A0 (en) 2003-11-23
AU2002211099B2 (en) 2007-01-11
JP4808756B2 (ja) 2011-11-02
CY1110101T1 (el) 2015-01-14
EP1325340A1 (fr) 2003-07-09
JP2009058517A (ja) 2009-03-19
EP1325340B1 (fr) 2008-10-15
IL155277A (en) 2011-07-31
EP1197755A1 (fr) 2002-04-17
AU1109902A (en) 2002-04-22
ES2317941T3 (es) 2009-05-01
JP2004511780A (ja) 2004-04-15
NZ524874A (en) 2004-09-24
US20120190564A1 (en) 2012-07-26
PT1325340E (pt) 2009-01-07

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