DK131725C - Analogifremgangsmade til fremstilling af 2,4-diaminoquinazoliner eller salte deraf - Google Patents

Analogifremgangsmade til fremstilling af 2,4-diaminoquinazoliner eller salte deraf

Info

Publication number
DK131725C
DK131725C DK478273*A DK478273A DK131725C DK 131725 C DK131725 C DK 131725C DK 478273 A DK478273 A DK 478273A DK 131725 C DK131725 C DK 131725C
Authority
DK
Denmark
Prior art keywords
diaminoquinazolins
salts
preparation
analogical procedure
analogical
Prior art date
Application number
DK478273*A
Other languages
Danish (da)
English (en)
Other versions
DK131725B (da
Inventor
J C Danilewicz
J E G Kemp
J R Wright
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK131725B publication Critical patent/DK131725B/da
Application granted granted Critical
Publication of DK131725C publication Critical patent/DK131725C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK478273*A 1972-09-09 1973-08-30 Analogifremgangsmade til fremstilling af 2,4-diaminoquinazoliner eller salte deraf DK131725C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4199272A GB1383409A (en) 1972-09-09 1972-09-09 Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DK131725B DK131725B (da) 1975-08-25
DK131725C true DK131725C (da) 1976-01-26

Family

ID=10422335

Family Applications (1)

Application Number Title Priority Date Filing Date
DK478273*A DK131725C (da) 1972-09-09 1973-08-30 Analogifremgangsmade til fremstilling af 2,4-diaminoquinazoliner eller salte deraf

Country Status (17)

Country Link
US (1) US3960861A (Direct)
JP (1) JPS4985078A (Direct)
AR (1) AR203373A1 (Direct)
AT (1) AT330785B (Direct)
BE (1) BE804558A (Direct)
CA (1) CA995673A (Direct)
DE (2) DE2345064C3 (Direct)
DK (1) DK131725C (Direct)
ES (1) ES418612A1 (Direct)
FR (1) FR2198751B1 (Direct)
GB (1) GB1383409A (Direct)
IE (1) IE38318B1 (Direct)
IN (2) IN139088B (Direct)
LU (1) LU68373A1 (Direct)
NL (1) NL161152C (Direct)
SU (1) SU555850A3 (Direct)
ZA (1) ZA735660B (Direct)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044136A (en) * 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
GR79603B (Direct) * 1982-07-24 1984-10-31 Pfizer
DE3464247D1 (de) * 1983-06-28 1987-07-23 Ciba Geigy Ag Chromogenic quinazoline compounds
KR930702292A (ko) * 1990-11-06 1993-09-08 알렌 제이. 스피겔 종양 치료 활성을 증대시키기 위한 퀴나졸린 유도체
KR0144833B1 (ko) * 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
DE4338396A1 (de) * 1993-11-10 1995-05-11 Basf Ag N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
IT1286302B1 (it) * 1996-04-10 1998-07-08 Rotta Research Lab Chinazoline-4-amino-2-(piperidino-1-il-4-sostituite) ad attivita' anti-ipertensiva, procedimento per la loro preparazione e loro uso
IN188411B (Direct) 1997-03-27 2002-09-21 Yuhan Corp
KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6900220B2 (en) 2001-01-02 2005-05-31 Syntex (U.S.A.) Llc Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists
MXPA05000131A (es) * 2002-07-05 2005-04-11 Hoffmann La Roche Derivados de quinazolina.
KR20090047450A (ko) * 2006-08-04 2009-05-12 메르츠 파마 게엠베하 운트 코. 카가아 치환된 피라졸로피리미딘, 이의 제조 방법 및 의약품으로서의 이의 용도
US8871756B2 (en) * 2011-08-11 2014-10-28 Hoffmann-La Roche Inc. Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease
WO2015018797A2 (en) * 2013-08-05 2015-02-12 Haplogen Gmbh Antiviral compounds
AR099134A1 (es) * 2014-01-24 2016-06-29 Hoffmann La Roche Procedimiento para la preparación de n-[(3-aminooxetán-3-il)metil]-2-(1,1-dioxo-3,5-dihidro-1,4-benzotiazepín-4-il)-6-metil-quinazolín-4-amina
EP3298017B1 (en) 2015-05-20 2019-08-14 H. Hoffnabb-La Roche Ag Compounds for treating spinal muscular atrophy
EP3322704B1 (en) 2015-07-16 2019-11-27 H. Hoffnabb-La Roche Ag Crystalline form of n-[(3-amino-3-oxetanyl)methyl]-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5h)-yl)-6-methyl-4-quinazolinamine for the treatment of respiratory syncytial virus (rsv) infections
EA036399B1 (ru) 2015-11-12 2020-11-06 Ф. Хоффманн-Ля Рош Аг Композиции для лечения спинальной мышечной атрофии
KR102488323B1 (ko) 2015-12-10 2023-01-12 피티씨 테라퓨틱스, 인크. 헌팅턴병 치료 또는 개선을 위한 조성물
JP6872550B2 (ja) 2015-12-10 2021-05-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 架橋されたピペリジン誘導体
FR3061494B1 (fr) 2016-12-29 2020-07-03 Arkema France Procede de synthese de dithiocarbamates cycliques fonctionnalises
CN111065626B (zh) 2017-06-05 2024-09-27 Ptc医疗公司 用于治疗亨廷顿氏舞蹈病的化合物
WO2019005993A1 (en) 2017-06-28 2019-01-03 Ptc Therapeutics, Inc. METHODS OF TREATING HUNTINGTON'S DISEASE
BR112019027717A2 (pt) 2017-06-28 2020-07-28 Ptc Therapeutics, Inc. métodos para tratar a doença de huntington
MX2020009957A (es) 2018-03-27 2021-01-15 Ptc Therapeutics Inc Compuestos para el tratamiento de enfermedad de hungtinton.
US11685746B2 (en) 2018-06-27 2023-06-27 Ptc Therapeutics, Inc. Heteroaryl compounds for treating Huntington's disease
US12139499B2 (en) 2018-06-27 2024-11-12 Ptc Therapeutics, Inc. Heteroaryl compounds for treating Huntington's disease
SI3814357T1 (sl) 2018-06-27 2024-09-30 Ptc Therapeutics, Inc. Heterociklične in heteroarilne spojine za zdravljenje Huntingtonove bolezni

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2945859A (en) * 1960-07-19 Diaminoquinazolines and method of
BE501634A (Direct) * 1950-03-02
US3155572A (en) * 1959-04-13 1964-11-03 Merck & Co Inc Compositions and methods for treating coccidiosis
GB1062357A (en) * 1965-03-23 1967-03-22 Pfizer & Co C Quinazolone derivatives
GB1131126A (en) * 1966-03-10 1968-10-23 Pfizer Ltd 2-vinyl-1,4-dihydroquinazoline derivatives
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3637701A (en) * 1969-03-03 1972-01-25 Sandoz Ag Certain nitrate derivatives of 4-aminoquinazolines
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Also Published As

Publication number Publication date
SU555850A3 (ru) 1977-04-25
GB1383409A (en) 1974-02-12
FR2198751B1 (Direct) 1977-01-28
IN141109B (Direct) 1977-01-22
IE38318L (en) 1974-03-09
IE38318B1 (en) 1978-02-15
AT330785B (de) 1976-07-26
NL7312350A (Direct) 1974-03-12
DE2345064B2 (de) 1979-03-08
DE2345064C3 (de) 1979-10-25
DE2366106B1 (de) 1979-06-21
DE2366106C2 (de) 1980-02-14
IN139088B (Direct) 1976-05-08
ATA774573A (de) 1975-10-15
US3960861A (en) 1976-06-01
AR203373A1 (es) 1975-09-08
ES418612A1 (es) 1976-07-16
BE804558A (fr) 1974-03-06
ZA735660B (en) 1974-07-31
NL161152C (nl) 1980-01-15
NL161152B (nl) 1979-08-15
CA995673A (en) 1976-08-24
JPS4985078A (Direct) 1974-08-15
DK131725B (da) 1975-08-25
LU68373A1 (Direct) 1975-05-21
AU5960673A (en) 1975-02-27
DE2345064A1 (de) 1974-04-11
FR2198751A1 (Direct) 1974-04-05

Similar Documents

Publication Publication Date Title
DK131725C (da) Analogifremgangsmade til fremstilling af 2,4-diaminoquinazoliner eller salte deraf
DK132172C (da) Analogifremgangsmade til fremstilling af 6,7-benzomorphaner eller salte deraf
DK140481B (da) Analogifremgangsmaade til fremstilling af hidtil ukendte penicillinestere eller salte heraf
DK140461B (da) Analogifremgangsmåde til fremstilling af 8-azapurin-6-oner eller salte deraf.
DK129650B (da) Analogifremgangsmåde til fremstilling af 1-phenoxy-2-hydroxy-3-amino-propaner eller salte deraf.
DK136468C (da) Analogifremgangsmade til fremstilling af 1-ethylimidazoler eller salte deraf
DK138020B (da) Analogifremgangsmåde til fremstilling af pyrazolodiazepinforbindelser eller salte deraf.
DK133106C (da) Analogifremgangsmade til fremstilling af 1-oxa-3,8-diazaspiro-(4,5)-decanderivater eller additionssalte heraf
DK130978B (da) Analogifremgangsmåde til fremstilling af 2-methylamino-4'-methyl-4-piperazinyl-6-chlor-5-methylthiopyrimidin eller salte deraf.
DK137011B (da) Analogifremgangsmade til fremstilling af oxazoler eller salte heraf
DK133301C (da) Analogifremgangsmade til fremstilling af penicillanforbindelser eller salte deraf
DK138745B (da) Fremgangsmåde til fremstilling af cephalexin eller salte deraf.
DK132662C (da) Analogifremgangsmade til fremstilling af 2beta,16beta-bis-(4-metyl-piperazino)-3alfa,17beta-diacetoxy-5alfa-androstan eller kvaternere salte deraf
DK138449B (da) Fremgangsmåde til fremstilling af D(-)-penicillamin eller salte deraf.
DK131855C (da) Fremgangsmade til fremstilling af 3,4-dihydropyridoner
DK139427C (da) Fremgangsmaade til fremstilling af benzensulfonylurinstoffer eller salte deraf
DK132831C (da) Analogifremgangsmade til fremstilling af 17beta-hydroxy-2,2,17-trimethyl-4-androsten-3-on
DK136906B (da) Analogifremgangsmåde til fremstilling af dibenzoxyrenazepinderivater eller salte deraf.
DK135941C (da) Analogifremgangsmaade til fremstilling af 1-cyclopropyl-1-phenyl-3-amino-1-propanoler eller syreaddittionssalte deraf
DK140762B (da) Analogifremgangsmaade til fremstilling af 7,8-dihydropteridiner eller tautomere eller salte deraf
DK132440C (da) Analogifremgangsmade til fremstilling af 11-oxygenerede 2-chlor-6alfa,9alfa-difluor-16alfa-methyl-3,20,21-trioxo-1,4-pregnadiener eller 21-aldehydhydrater, -estere eller -acetaler deraf
DK133468C (da) Analogifremgangsmade til fremstilling af 1-benzyl-3-amino-pyrazoloner-(5).
DK131724C (da) Analogifremgangsmade til fremstilling af bis-(4,7-dihydroxykumarinyl-3)-eddikesyre eller salte heraf med baser
DK136363C (da) Fremgangsmade til fremstilling af 1-ethylimidazoler eller salte deraf
DK132123C (da) Analogifremgangsmade til fremstilling af 11-oxygenerede pregnen-(17,16alfa-d)-1',3'-oxathiolaner