AR203373A1 - Procedimiento para preparar 4-amino-quinazolinas - Google Patents
Procedimiento para preparar 4-amino-quinazolinasInfo
- Publication number
- AR203373A1 AR203373A1 AR249880A AR24988073A AR203373A1 AR 203373 A1 AR203373 A1 AR 203373A1 AR 249880 A AR249880 A AR 249880A AR 24988073 A AR24988073 A AR 24988073A AR 203373 A1 AR203373 A1 AR 203373A1
- Authority
- AR
- Argentina
- Prior art keywords
- quinazolines
- amino
- prepare
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4199272A GB1383409A (en) | 1972-09-09 | 1972-09-09 | Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR203373A1 true AR203373A1 (es) | 1975-09-08 |
Family
ID=10422335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR249880A AR203373A1 (es) | 1972-09-09 | 1973-09-03 | Procedimiento para preparar 4-amino-quinazolinas |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3960861A (Direct) |
| JP (1) | JPS4985078A (Direct) |
| AR (1) | AR203373A1 (Direct) |
| AT (1) | AT330785B (Direct) |
| BE (1) | BE804558A (Direct) |
| CA (1) | CA995673A (Direct) |
| DE (2) | DE2345064C3 (Direct) |
| DK (1) | DK131725C (Direct) |
| ES (1) | ES418612A1 (Direct) |
| FR (1) | FR2198751B1 (Direct) |
| GB (1) | GB1383409A (Direct) |
| IE (1) | IE38318B1 (Direct) |
| IN (2) | IN139088B (Direct) |
| LU (1) | LU68373A1 (Direct) |
| NL (1) | NL161152C (Direct) |
| SU (1) | SU555850A3 (Direct) |
| ZA (1) | ZA735660B (Direct) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4044136A (en) * | 1972-09-09 | 1977-08-23 | Pfizer Inc. | Aminoquinazoline therapeutic agents |
| GR79603B (Direct) * | 1982-07-24 | 1984-10-31 | Pfizer | |
| DE3464247D1 (de) * | 1983-06-28 | 1987-07-23 | Ciba Geigy Ag | Chromogenic quinazoline compounds |
| KR930702292A (ko) * | 1990-11-06 | 1993-09-08 | 알렌 제이. 스피겔 | 종양 치료 활성을 증대시키기 위한 퀴나졸린 유도체 |
| KR0144833B1 (ko) * | 1992-12-28 | 1998-07-15 | 김태훈 | 신규의 퀴나졸린 유도체 및 그의 제조방법 |
| DE4338396A1 (de) * | 1993-11-10 | 1995-05-11 | Basf Ag | N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung |
| IT1286302B1 (it) * | 1996-04-10 | 1998-07-08 | Rotta Research Lab | Chinazoline-4-amino-2-(piperidino-1-il-4-sostituite) ad attivita' anti-ipertensiva, procedimento per la loro preparazione e loro uso |
| IN188411B (Direct) | 1997-03-27 | 2002-09-21 | Yuhan Corp | |
| KR100272471B1 (ko) | 1998-11-17 | 2000-11-15 | 김선진 | 신규의 피리미딘 유도체 및 그의 제조방법 |
| US6900220B2 (en) | 2001-01-02 | 2005-05-31 | Syntex (U.S.A.) Llc | Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists |
| MXPA05000131A (es) * | 2002-07-05 | 2005-04-11 | Hoffmann La Roche | Derivados de quinazolina. |
| KR20090047450A (ko) * | 2006-08-04 | 2009-05-12 | 메르츠 파마 게엠베하 운트 코. 카가아 | 치환된 피라졸로피리미딘, 이의 제조 방법 및 의약품으로서의 이의 용도 |
| US8871756B2 (en) * | 2011-08-11 | 2014-10-28 | Hoffmann-La Roche Inc. | Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease |
| WO2015018797A2 (en) * | 2013-08-05 | 2015-02-12 | Haplogen Gmbh | Antiviral compounds |
| AR099134A1 (es) * | 2014-01-24 | 2016-06-29 | Hoffmann La Roche | Procedimiento para la preparación de n-[(3-aminooxetán-3-il)metil]-2-(1,1-dioxo-3,5-dihidro-1,4-benzotiazepín-4-il)-6-metil-quinazolín-4-amina |
| EP3298017B1 (en) | 2015-05-20 | 2019-08-14 | H. Hoffnabb-La Roche Ag | Compounds for treating spinal muscular atrophy |
| EP3322704B1 (en) | 2015-07-16 | 2019-11-27 | H. Hoffnabb-La Roche Ag | Crystalline form of n-[(3-amino-3-oxetanyl)methyl]-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5h)-yl)-6-methyl-4-quinazolinamine for the treatment of respiratory syncytial virus (rsv) infections |
| EA036399B1 (ru) | 2015-11-12 | 2020-11-06 | Ф. Хоффманн-Ля Рош Аг | Композиции для лечения спинальной мышечной атрофии |
| KR102488323B1 (ko) | 2015-12-10 | 2023-01-12 | 피티씨 테라퓨틱스, 인크. | 헌팅턴병 치료 또는 개선을 위한 조성물 |
| JP6872550B2 (ja) | 2015-12-10 | 2021-05-19 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 架橋されたピペリジン誘導体 |
| FR3061494B1 (fr) | 2016-12-29 | 2020-07-03 | Arkema France | Procede de synthese de dithiocarbamates cycliques fonctionnalises |
| CN111065626B (zh) | 2017-06-05 | 2024-09-27 | Ptc医疗公司 | 用于治疗亨廷顿氏舞蹈病的化合物 |
| WO2019005993A1 (en) | 2017-06-28 | 2019-01-03 | Ptc Therapeutics, Inc. | METHODS OF TREATING HUNTINGTON'S DISEASE |
| BR112019027717A2 (pt) | 2017-06-28 | 2020-07-28 | Ptc Therapeutics, Inc. | métodos para tratar a doença de huntington |
| MX2020009957A (es) | 2018-03-27 | 2021-01-15 | Ptc Therapeutics Inc | Compuestos para el tratamiento de enfermedad de hungtinton. |
| US11685746B2 (en) | 2018-06-27 | 2023-06-27 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating Huntington's disease |
| US12139499B2 (en) | 2018-06-27 | 2024-11-12 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating Huntington's disease |
| SI3814357T1 (sl) | 2018-06-27 | 2024-09-30 | Ptc Therapeutics, Inc. | Heterociklične in heteroarilne spojine za zdravljenje Huntingtonove bolezni |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2945859A (en) * | 1960-07-19 | Diaminoquinazolines and method of | ||
| BE501634A (Direct) * | 1950-03-02 | |||
| US3155572A (en) * | 1959-04-13 | 1964-11-03 | Merck & Co Inc | Compositions and methods for treating coccidiosis |
| GB1062357A (en) * | 1965-03-23 | 1967-03-22 | Pfizer & Co C | Quinazolone derivatives |
| GB1131126A (en) * | 1966-03-10 | 1968-10-23 | Pfizer Ltd | 2-vinyl-1,4-dihydroquinazoline derivatives |
| US3511836A (en) * | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
| US3637701A (en) * | 1969-03-03 | 1972-01-25 | Sandoz Ag | Certain nitrate derivatives of 4-aminoquinazolines |
| US3663706A (en) * | 1969-09-29 | 1972-05-16 | Pfizer | Use of 2,4-diaminoquinazolines as hypotensive agents |
| US3669968A (en) * | 1970-05-21 | 1972-06-13 | Pfizer | Trialkoxy quinazolines |
-
1972
- 1972-09-09 GB GB4199272A patent/GB1383409A/en not_active Expired
-
1973
- 1973-08-20 ZA ZA735660A patent/ZA735660B/xx unknown
- 1973-08-21 IN IN1920/CAL/73A patent/IN139088B/en unknown
- 1973-08-30 DK DK478273*A patent/DK131725C/da active
- 1973-08-31 CA CA180,089A patent/CA995673A/en not_active Expired
- 1973-09-03 IE IE1560/73A patent/IE38318B1/xx unknown
- 1973-09-03 AR AR249880A patent/AR203373A1/es active
- 1973-09-04 JP JP48098934A patent/JPS4985078A/ja active Pending
- 1973-09-05 US US05/394,491 patent/US3960861A/en not_active Expired - Lifetime
- 1973-09-06 DE DE2345064A patent/DE2345064C3/de not_active Expired
- 1973-09-06 AT AT774573A patent/AT330785B/de active
- 1973-09-06 BE BE135402A patent/BE804558A/xx unknown
- 1973-09-06 DE DE2366106A patent/DE2366106C2/de not_active Expired
- 1973-09-07 LU LU68373A patent/LU68373A1/xx unknown
- 1973-09-07 FR FR7332315A patent/FR2198751B1/fr not_active Expired
- 1973-09-07 NL NL7312350.A patent/NL161152C/xx not_active IP Right Cessation
- 1973-09-08 ES ES418612A patent/ES418612A1/es not_active Expired
-
1975
- 1975-01-08 SU SU2095549A patent/SU555850A3/ru active
- 1975-07-11 IN IN1357/CAL/75A patent/IN141109B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU555850A3 (ru) | 1977-04-25 |
| GB1383409A (en) | 1974-02-12 |
| FR2198751B1 (Direct) | 1977-01-28 |
| IN141109B (Direct) | 1977-01-22 |
| IE38318L (en) | 1974-03-09 |
| IE38318B1 (en) | 1978-02-15 |
| AT330785B (de) | 1976-07-26 |
| NL7312350A (Direct) | 1974-03-12 |
| DE2345064B2 (de) | 1979-03-08 |
| DE2345064C3 (de) | 1979-10-25 |
| DE2366106B1 (de) | 1979-06-21 |
| DE2366106C2 (de) | 1980-02-14 |
| IN139088B (Direct) | 1976-05-08 |
| ATA774573A (de) | 1975-10-15 |
| DK131725C (da) | 1976-01-26 |
| US3960861A (en) | 1976-06-01 |
| ES418612A1 (es) | 1976-07-16 |
| BE804558A (fr) | 1974-03-06 |
| ZA735660B (en) | 1974-07-31 |
| NL161152C (nl) | 1980-01-15 |
| NL161152B (nl) | 1979-08-15 |
| CA995673A (en) | 1976-08-24 |
| JPS4985078A (Direct) | 1974-08-15 |
| DK131725B (da) | 1975-08-25 |
| LU68373A1 (Direct) | 1975-05-21 |
| AU5960673A (en) | 1975-02-27 |
| DE2345064A1 (de) | 1974-04-11 |
| FR2198751A1 (Direct) | 1974-04-05 |
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