DK129127B - Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 2-(furylmethyl)-6,7-benzomorphaner eller deres syreadditionssalte. - Google Patents
Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 2-(furylmethyl)-6,7-benzomorphaner eller deres syreadditionssalte.Info
- Publication number
- DK129127B DK129127B DK53372AA DK53372A DK129127B DK 129127 B DK129127 B DK 129127B DK 53372A A DK53372A A DK 53372AA DK 53372 A DK53372 A DK 53372A DK 129127 B DK129127 B DK 129127B
- Authority
- DK
- Denmark
- Prior art keywords
- benzomorphans
- furylmethyl
- racemic
- preparation
- acid addition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2105743A DE2105743C3 (de) | 1971-02-08 | 1971-02-08 | 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung |
| DE19712108954 DE2108954A1 (en) | 1971-02-25 | 1971-02-25 | 2-(furylmethyl)-6,7-benzomorphans - useful as cns active agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK129127B true DK129127B (da) | 1974-08-26 |
| DK129127C DK129127C (US08088918-20120103-C00476.png) | 1975-02-10 |
Family
ID=25760626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK53372AA DK129127B (da) | 1971-02-08 | 1972-02-07 | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 2-(furylmethyl)-6,7-benzomorphaner eller deres syreadditionssalte. |
Country Status (25)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2229695A1 (de) * | 1972-06-19 | 1974-01-31 | Boehringer Sohn Ingelheim | 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung |
| US4010164A (en) * | 1973-03-28 | 1977-03-01 | Boehringer Ingelheim Gmbh | N-(furyl-methyl)-2-hydroxy-5,9,9-trimethyl-benzomorphans and salts thereof |
| SU510999A3 (ru) * | 1973-10-27 | 1976-04-15 | К.Х.Берингер Зон, (Фирма) | Способ получени (метоксиметил-фурилметил)6,7-бензоморфанов илиморфинанов |
| US4087532A (en) * | 1974-03-09 | 1978-05-02 | Boehringer Ingelheim Gmbh | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof |
| DE2437610A1 (de) * | 1974-08-05 | 1976-02-26 | Boehringer Sohn Ingelheim | Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung |
| GB1575009A (en) * | 1976-06-21 | 1980-09-17 | Acf Chemiefarma Nv | 6,7-benzomorphan derivatives |
| DE2716687A1 (de) * | 1977-04-15 | 1978-10-19 | Boehringer Sohn Ingelheim | 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel |
| DE3839659A1 (de) * | 1988-11-24 | 1990-05-31 | Boehringer Ingelheim Kg | Verwendung von benzomorphanen zur zytoprotektion |
| AR069545A1 (es) * | 2007-11-16 | 2010-02-03 | Boehringer Ingelheim Pharma | Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y |
| EP2245014B1 (en) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| TW200950780A (en) | 2008-05-13 | 2009-12-16 | Boehringer Ingelheim Int | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| WO2013025664A1 (en) | 2011-08-17 | 2013-02-21 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1281227A (fr) * | 1958-09-22 | 1962-01-12 | Smith Kline French Lab | Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane |
| FR1538362A (fr) * | 1966-05-20 | 1968-09-06 | Merck & Co Inc | Dérivés du benzomorphane |
-
1972
- 1972-01-26 CS CS483A patent/CS166801B2/cs unknown
- 1972-01-26 CS CS7061*A patent/CS166804B2/cs unknown
- 1972-01-26 CS CS7060*A patent/CS166803B2/cs unknown
- 1972-01-26 CS CS7059*A patent/CS166802B2/cs unknown
- 1972-02-01 US US00222669A patent/US3823150A/en not_active Expired - Lifetime
- 1972-02-03 CH CH158472A patent/CH573933A5/xx not_active IP Right Cessation
- 1972-02-03 CH CH1565575A patent/CH573935A5/xx not_active IP Right Cessation
- 1972-02-03 CH CH1565475A patent/CH574442A5/xx not_active IP Right Cessation
- 1972-02-03 CH CH1565375A patent/CH573934A5/xx not_active IP Right Cessation
- 1972-02-04 JP JP1276272A patent/JPS5545555B1/ja active Pending
- 1972-02-04 SU SU1918909A patent/SU469246A3/ru active
- 1972-02-04 SU SU1918905A patent/SU467519A3/ru active
- 1972-02-04 SU SU1918908A patent/SU479290A3/ru active
- 1972-02-04 SU SU1744912A patent/SU421187A3/ru active
- 1972-02-05 BG BG22164A patent/BG19600A3/xx unknown
- 1972-02-05 BG BG19654A patent/BG19800A3/xx unknown
- 1972-02-05 BG BG22165A patent/BG20792A3/xx unknown
- 1972-02-07 FI FI327/72A patent/FI57758C/fi active
- 1972-02-07 CA CA134,023A patent/CA969938A/en not_active Expired
- 1972-02-07 GB GB559472A patent/GB1384115A/en not_active Expired
- 1972-02-07 DD DD160731A patent/DD95847A5/xx unknown
- 1972-02-07 SE SE01397/72A patent/SE363630B/xx unknown
- 1972-02-07 AT AT168773A patent/AT318602B/de not_active IP Right Cessation
- 1972-02-07 NO NO325/72*[A patent/NO134054C/no unknown
- 1972-02-07 IL IL38699A patent/IL38699A/xx unknown
- 1972-02-07 NL NLAANVRAGE7201551,A patent/NL171898C/xx not_active IP Right Cessation
- 1972-02-07 AT AT168673A patent/AT318601B/de not_active IP Right Cessation
- 1972-02-07 BE BE779058A patent/BE779058A/xx not_active IP Right Cessation
- 1972-02-07 YU YU1657/72A patent/YU35016B/xx unknown
- 1972-02-07 PL PL1972153362A patent/PL78312B1/pl unknown
- 1972-02-07 AT AT96272A patent/AT312587B/de active
- 1972-02-07 YU YU00279/72A patent/YU27972A/xx unknown
- 1972-02-07 DK DK53372AA patent/DK129127B/da not_active IP Right Cessation
- 1972-02-07 ES ES399536A patent/ES399536A1/es not_active Expired
- 1972-02-08 RO RO72543A patent/RO59193A/ro unknown
- 1972-02-08 HU HUBO1349A patent/HU162946B/hu unknown
- 1972-02-08 FR FR7204151A patent/FR2124564B1/fr not_active Expired
- 1972-02-08 RO RO72541A patent/RO59251A/ro unknown
- 1972-02-08 PH PH13256A patent/PH10743A/en unknown
- 1972-02-08 IE IE156/72A patent/IE36071B1/xx unknown
- 1972-02-08 RO RO72542A patent/RO59165A/ro unknown
- 1972-02-08 RO RO69695A patent/RO58981A/ro unknown
- 1972-05-09 PL PL1972155268A patent/PL84115B3/pl unknown
- 1972-10-17 RO RO7200080094A patent/RO63052A/ro unknown
- 1972-11-04 ES ES408276A patent/ES408276A1/es not_active Expired
- 1972-11-04 ES ES408275A patent/ES408275A1/es not_active Expired
- 1972-11-04 ES ES408274A patent/ES408274A1/es not_active Expired
-
1978
- 1978-07-18 YU YU1720/78A patent/YU35255B/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK136904B (da) | Analogifremgangsmade til fremstilling af racemiske eller optisk aktive 2-(heteroarylmethyl)-5,9beta-dialkyl-6,7-benzomorphaner eller syreadditionssalte deraf | |
| DK131029B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 1-phenoxy-2-hydroxy-3-alkylaminopropaner eller syreadditionssalte deraf. | |
| DK129447B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 1-phenoxy-2-hydroxy-3-sek.-alkylaminopropaner eller syreadditionssalte heraf. | |
| DK138602B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive penicilliner eller salte deraf. | |
| DK142750C (da) | Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive dopaminderivater eller syreadditionssalte deraf | |
| DK140281B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 1-phenoxy-2-hydroxy-3-cycloalkylaminopropaner eller syreadditionssalte heraf. | |
| DK136527B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive p-alkoxyfenoxypropanolaminer eller syreadditionssalte deraf. | |
| DK129127B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 2-(furylmethyl)-6,7-benzomorphaner eller deres syreadditionssalte. | |
| DK136713B (da) | Analogifremgangsmåde til fremstilling af alfa-aryl-4-substituerede piperidinoalkanolderivater eller deres syreadditionssalte. | |
| DK122133B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive substituerede 3-alkoxythianaphthen-2-carboxamider eller syreadditionssalte eller kvaternære ammoniumsalte deraf. | |
| DK121512B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive substituerede 5-phenyl-6,7-benzomorphaner eller syreadditionssalte deraf. | |
| DK126644B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive hydroxycrotonsyrer eller salte deraf med uorganiske eller organiske baser. | |
| DK131778B (da) | Fremgangsmåde til fremstilling af substituerede 3-hydroksymetylisokinolinderivater eller syreadditionssalte heraf. | |
| DK139582B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive benzocycloheptaisoquinolin-forbindelser eller syreadditionssalte deraf. | |
| DK129235B (da) | Fremgangsmåde til fremstilling af racemiske eller optisk aktive quinolinderivater eller syreadditionssalte deraf. | |
| DK131857B (da) | Analogifremgangsmåde til fremstilling af 4-hydroxymethyl-1-phthalazonderivater eller syreadditionssalte deraf. | |
| DK138943B (da) | Analogifremgangsmåde til fremstilling af substituerede dibenzocyclohepten-carboxamider eller syreadditionssalte deraf. | |
| DK130344B (da) | Analogifremgangsmåde til fremstilling af benzofuranderivater eller syreadditionssalte deraf. | |
| DK136823B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive derivater af imidazo(2,1-b)thiazol eller syreadditionssalte deraf. | |
| DK123102B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive benzo[b]thiopheneddikesyreforbindelser eller carboxylatsalte deraf. | |
| DK129992B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 3,5-disubstituerede fenylætanolaminforbindelser eller terapeutisk acceptable syreadditionssalte deraf. | |
| DK136069B (da) | Fremgangsmåde til fremstilling af quinolinderivater, antipoder eller racemater eller syreadditionssalte deraf. | |
| DK134014B (da) | Analogifremgangsmåde til fremstilling af cycloalkyllactamimider eller syreadditionssalte deraf. | |
| DK131470B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive thiazolino-pyrimidin-5-on derivater eller syreadditionssalte deraf. | |
| DK129718B (da) | Analogifremgangsmåde til fremstilling af tiazolino-pyrimidin-5-oner eller deres syreadditionssalte eller de tilsvarende optisk aktive forbindelser. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |