DK1248651T3 - Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertension - Google Patents
Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertensionInfo
- Publication number
- DK1248651T3 DK1248651T3 DK01903871T DK01903871T DK1248651T3 DK 1248651 T3 DK1248651 T3 DK 1248651T3 DK 01903871 T DK01903871 T DK 01903871T DK 01903871 T DK01903871 T DK 01903871T DK 1248651 T3 DK1248651 T3 DK 1248651T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- heterotrimer
- product
- arterial hypertension
- signal transduction
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0000105A FR2803525B1 (fr) | 2000-01-06 | 2000-01-06 | Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1248651T3 true DK1248651T3 (da) | 2006-01-02 |
Family
ID=8845646
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01903871T DK1248651T3 (da) | 2000-01-06 | 2001-01-05 | Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertension |
Country Status (11)
Country | Link |
---|---|
US (2) | US6846822B2 (ja) |
EP (1) | EP1248651B1 (ja) |
JP (1) | JP2003520787A (ja) |
AT (1) | ATE302026T1 (ja) |
AU (1) | AU3183801A (ja) |
CA (1) | CA2395955A1 (ja) |
DE (1) | DE60112719T2 (ja) |
DK (1) | DK1248651T3 (ja) |
ES (1) | ES2247060T3 (ja) |
FR (1) | FR2803525B1 (ja) |
WO (1) | WO2001049322A1 (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2803525B1 (fr) * | 2000-01-06 | 2002-05-03 | Sod Conseils Rech Applic | Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle |
EP1750862B1 (en) * | 2004-06-04 | 2011-01-05 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing irbesartan |
FR2879460B1 (fr) * | 2004-12-17 | 2007-02-23 | Sod Conseils Rech Applic | Associations anti-douleur comprenant un derive de dihydroimidazopyrazine |
TW200800213A (en) | 2005-09-02 | 2008-01-01 | Abbott Lab | Novel imidazo based heterocycles |
AR077463A1 (es) | 2009-07-09 | 2011-08-31 | Irm Llc | Derivados de imidazo[1, 2 - a]pirazina y su uso en medicamentos para el tratamiento de enfermedades parasitarias |
FR3002453B1 (fr) * | 2013-02-28 | 2015-08-07 | Univ Bordeaux Segalen | Nouvelles combinaisons comprenant un extrait polyphenolique de marc de raisin avec un antihypertenseur et leurs utilisations |
CN110691597A (zh) | 2017-04-24 | 2020-01-14 | 诺华股份有限公司 | 2-氨基-1-(2-(4-氟苯基)-3-(4-氟苯基氨基)-8,8-二甲基-5,6-二氢咪唑并[1,2-a]吡嗪-7(8H)-基)乙酮及其组合的治疗方案 |
CN112480122B (zh) * | 2020-11-24 | 2022-03-22 | 中山大学 | 一种四氢咪唑[1,2-a]吡嗪类化合物、组合物及其制备方法与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6673927B2 (en) * | 1996-02-16 | 2004-01-06 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Farnesyl transferase inhibitors |
DE19637518A1 (de) * | 1996-09-13 | 1998-04-09 | Winfried Siffert | PTX-sensitive G-Proteine, ihre Herstellung und Verwendung |
GT199800126A (es) * | 1997-08-29 | 2000-01-29 | Terapia de combinacion. | |
FR2803525B1 (fr) * | 2000-01-06 | 2002-05-03 | Sod Conseils Rech Applic | Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle |
-
2000
- 2000-01-06 FR FR0000105A patent/FR2803525B1/fr not_active Expired - Fee Related
-
2001
- 2001-01-05 US US10/169,656 patent/US6846822B2/en not_active Expired - Fee Related
- 2001-01-05 JP JP2001549688A patent/JP2003520787A/ja active Pending
- 2001-01-05 CA CA002395955A patent/CA2395955A1/fr not_active Abandoned
- 2001-01-05 DE DE60112719T patent/DE60112719T2/de not_active Expired - Lifetime
- 2001-01-05 AT AT01903871T patent/ATE302026T1/de active
- 2001-01-05 DK DK01903871T patent/DK1248651T3/da active
- 2001-01-05 WO PCT/FR2001/000027 patent/WO2001049322A1/fr active IP Right Grant
- 2001-01-05 AU AU31838/01A patent/AU3183801A/en not_active Abandoned
- 2001-01-05 EP EP01903871A patent/EP1248651B1/fr not_active Expired - Lifetime
- 2001-01-05 ES ES01903871T patent/ES2247060T3/es not_active Expired - Lifetime
-
2004
- 2004-12-13 US US11/010,727 patent/US7132553B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2395955A1 (fr) | 2001-07-12 |
US20050171113A1 (en) | 2005-08-04 |
ES2247060T3 (es) | 2006-03-01 |
WO2001049322A1 (fr) | 2001-07-12 |
ATE302026T1 (de) | 2005-09-15 |
JP2003520787A (ja) | 2003-07-08 |
US6846822B2 (en) | 2005-01-25 |
FR2803525B1 (fr) | 2002-05-03 |
EP1248651B1 (fr) | 2005-08-17 |
US7132553B2 (en) | 2006-11-07 |
AU3183801A (en) | 2001-07-16 |
DE60112719D1 (de) | 2005-09-22 |
FR2803525A1 (fr) | 2001-07-13 |
DE60112719T2 (de) | 2006-06-08 |
EP1248651A1 (fr) | 2002-10-16 |
US20030004168A1 (en) | 2003-01-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE371656T1 (de) | Heteroaryl-pyrimidinderivate als jak-inhibitoren | |
MA28279A1 (fr) | Derives d'indole et utilisation de ceux-ci comme inhibiteurs de kinase, notamment des inhibiteurs de ikk2 | |
TR200201505T2 (tr) | Terapötik maddeler olarak pirazolopirimidinler | |
CY1109529T1 (el) | 2-(αμινο-υποκατεστημενες)-4-αρυλο πυραμιδινες και σχετικες ενωσεις που χρησιμευουν στην αγωγη φλεγμονωδων νοσηματων | |
BR0316350A (pt) | Diaminotriazóis úteis como inibidores de proteìna cinases | |
CY1110498T1 (el) | Παραγωγα πυραζολης ως αναστολεις των κινασων τυροσινης υποδοχεα | |
CY1109227T1 (el) | Παραγωγα της 5-φαινυλο-4-μεθυλο-θειαζολ-2-υλ-αμινης ως αναστολεις των ενζυμων κινασης της φωσφατιδυλινοσιτολης 3 (p13) για την θεραπεια των φλεγμονωδων ασθενειων των αεραγωγων | |
NO20025601L (no) | Arylmetylaminderivater for anvendelse som tryptaseinhibitorer | |
DE50310516D1 (de) | Fredericamycin-derivate | |
SE9800836D0 (sv) | New Compounds | |
ATE465146T1 (de) | 1h-indolderivate als hochselektive cyclooxygenase-2-inhibitoren | |
TR200200778T2 (tr) | Pirazol türevleri. | |
DK1206474T3 (da) | Sulfonylphenylpyrazolforbindelser anvendelige som cox-2-inhibitorer | |
DE60121461D1 (de) | Kondensierte pyridoindolderivate | |
DK1097173T3 (da) | Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler | |
BR0307071A (pt) | ésteres hidroxamato do ácido n-(fenil 4-substituìdo)-antranìlico | |
DK1248651T3 (da) | Produkt omfattende en heterotrimer G-proteinsignaltransduktionshæmmer kombineret med et antihypertensivt middel til terapeutisk anvendelse i behandlingen af arteriel hypertension | |
CY1105591T1 (el) | Αναστολεις για συνθαση του 20-ηετε | |
ATE523199T1 (de) | Pyridazinverbindungen und verfahren | |
TR200000907T2 (tr) | Nötrofil elastaz inhibitörleri olarak pirolopirolon türevleri. | |
ATE384714T1 (de) | Pyrazolderivate | |
ATE259813T1 (de) | Triazolopyrimidinderivate | |
ME00549B (me) | Upotreba inhibitora il-18 za liječenje i/ili prevenciju srčanih oboljenja | |
DE60305053D1 (de) | Pyrimidinderivate als selektive cox-2-inhibitoren | |
ATE287416T1 (de) | Thrombin inhibitoren |