DE60112719D1 - Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonie - Google Patents

Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonie

Info

Publication number
DE60112719D1
DE60112719D1 DE60112719T DE60112719T DE60112719D1 DE 60112719 D1 DE60112719 D1 DE 60112719D1 DE 60112719 T DE60112719 T DE 60112719T DE 60112719 T DE60112719 T DE 60112719T DE 60112719 D1 DE60112719 D1 DE 60112719D1
Authority
DE
Germany
Prior art keywords
treatment
inhibitor
heterometric
proteins
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60112719T
Other languages
English (en)
Other versions
DE60112719T2 (de
Inventor
Gregoire Prevost
Marc Teillot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of DE60112719D1 publication Critical patent/DE60112719D1/de
Application granted granted Critical
Publication of DE60112719T2 publication Critical patent/DE60112719T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60112719T 2000-01-06 2001-01-05 Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonie Expired - Lifetime DE60112719T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0000105 2000-01-06
FR0000105A FR2803525B1 (fr) 2000-01-06 2000-01-06 Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle
PCT/FR2001/000027 WO2001049322A1 (fr) 2000-01-06 2001-01-05 Produit comprenant un inhibiteur de la transduction des signaux des proteines g heterotrimeriques en association avec un agent anti-hypertenseur pour une utilisation therapeutique dans le traitement de l'hypertension arterielle

Publications (2)

Publication Number Publication Date
DE60112719D1 true DE60112719D1 (de) 2005-09-22
DE60112719T2 DE60112719T2 (de) 2006-06-08

Family

ID=8845646

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60112719T Expired - Lifetime DE60112719T2 (de) 2000-01-06 2001-01-05 Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonie

Country Status (11)

Country Link
US (2) US6846822B2 (de)
EP (1) EP1248651B1 (de)
JP (1) JP2003520787A (de)
AT (1) ATE302026T1 (de)
AU (1) AU3183801A (de)
CA (1) CA2395955A1 (de)
DE (1) DE60112719T2 (de)
DK (1) DK1248651T3 (de)
ES (1) ES2247060T3 (de)
FR (1) FR2803525B1 (de)
WO (1) WO2001049322A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2803525B1 (fr) * 2000-01-06 2002-05-03 Sod Conseils Rech Applic Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle
JP4880591B2 (ja) 2004-06-04 2012-02-22 テバ ファーマシューティカル インダストリーズ リミティド イルベサルタンを含む医薬組成物
FR2879460B1 (fr) * 2004-12-17 2007-02-23 Sod Conseils Rech Applic Associations anti-douleur comprenant un derive de dihydroimidazopyrazine
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
TWI421252B (zh) 2009-07-09 2014-01-01 Irm Llc 用於治療寄生蟲疾病之化合物及組合物
FR3002453B1 (fr) * 2013-02-28 2015-08-07 Univ Bordeaux Segalen Nouvelles combinaisons comprenant un extrait polyphenolique de marc de raisin avec un antihypertenseur et leurs utilisations
JP7377717B2 (ja) 2017-04-24 2023-11-10 ノバルティス アーゲー ２－アミノ－ｌ－（２－（４－フルオロフェニル）－３－（４－フルオロフェニルアミノ）－８，８－ジメチル－５，６－ジヒドロイミダゾ［１，２－ａ］ピラジン－７（８ｈ）－イル）エタノン及びそれらの組み合わせの治療レジメン
CN112480122B (zh) * 2020-11-24 2022-03-22 中山大学 一种四氢咪唑[1,2-a]吡嗪类化合物、组合物及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673927B2 (en) * 1996-02-16 2004-01-06 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Farnesyl transferase inhibitors
DE19637518A1 (de) * 1996-09-13 1998-04-09 Winfried Siffert PTX-sensitive G-Proteine, ihre Herstellung und Verwendung
GT199800126A (es) * 1997-08-29 2000-01-29 Terapia de combinacion.
FR2803525B1 (fr) * 2000-01-06 2002-05-03 Sod Conseils Rech Applic Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle

Also Published As

Publication number Publication date
US7132553B2 (en) 2006-11-07
US20050171113A1 (en) 2005-08-04
WO2001049322A1 (fr) 2001-07-12
ES2247060T3 (es) 2006-03-01
CA2395955A1 (fr) 2001-07-12
US20030004168A1 (en) 2003-01-02
JP2003520787A (ja) 2003-07-08
EP1248651A1 (de) 2002-10-16
ATE302026T1 (de) 2005-09-15
US6846822B2 (en) 2005-01-25
FR2803525B1 (fr) 2002-05-03
DK1248651T3 (da) 2006-01-02
FR2803525A1 (fr) 2001-07-13
EP1248651B1 (de) 2005-08-17
AU3183801A (en) 2001-07-16
DE60112719T2 (de) 2006-06-08

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DE60112719D1 (de) Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterometrischen g proteinen in kombination mit einem antihypertensiven mittel zu einer therapeutischen verwendung in der behandlung von arterieller hypertonie
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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR