DK123526B - Fremgangsmåde til fremstilling af 6-chlor-2,3,4,5-tetrahydro-1H-3-benzazepin eller syreadditionssalte deraf. - Google Patents

Fremgangsmåde til fremstilling af 6-chlor-2,3,4,5-tetrahydro-1H-3-benzazepin eller syreadditionssalte deraf.

Info

Publication number
DK123526B
DK123526B DK383268AA DK383268A DK123526B DK 123526 B DK123526 B DK 123526B DK 383268A A DK383268A A DK 383268AA DK 383268 A DK383268 A DK 383268A DK 123526 B DK123526 B DK 123526B
Authority
DK
Denmark
Prior art keywords
benzazepine
tetrahydro
chloro
preparation
acid addition
Prior art date
Application number
DK383268AA
Other languages
Danish (da)
English (en)
Inventor
E Habicht
K Hoegerle
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK123526B publication Critical patent/DK123526B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK383268AA 1968-02-09 1968-08-08 Fremgangsmåde til fremstilling af 6-chlor-2,3,4,5-tetrahydro-1H-3-benzazepin eller syreadditionssalte deraf. DK123526B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (de) 1968-02-09 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
DK123526B true DK123526B (da) 1972-07-03

Family

ID=4223010

Family Applications (1)

Application Number Title Priority Date Filing Date
DK383268AA DK123526B (da) 1968-02-09 1968-08-08 Fremgangsmåde til fremstilling af 6-chlor-2,3,4,5-tetrahydro-1H-3-benzazepin eller syreadditionssalte deraf.

Country Status (10)

Country Link
AT (1) AT277257B (xx)
BE (1) BE719631A (xx)
CH (1) CH498122A (xx)
DE (1) DE1795132A1 (xx)
DK (1) DK123526B (xx)
ES (1) ES357247A1 (xx)
FR (1) FR1598948A (xx)
GB (1) GB1225053A (xx)
IL (1) IL30458A (xx)
NL (1) NL6811311A (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2171879A1 (en) * 1972-02-14 1973-09-28 Pennwalt Corp 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
US4160765A (en) * 1976-11-17 1979-07-10 Smithkline Corporation Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4197297A (en) * 1976-11-17 1980-04-08 Smithkline Corporation 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
CN1805938B (zh) 2003-06-17 2010-06-16 艾尼纳制药公司 用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
DK2332921T3 (en) 2003-06-17 2016-05-09 Arena Pharm Inc 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3benzazepine hydrochloride
TW200510324A (en) * 2003-08-11 2005-03-16 Lilly Co Eli 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist
PL1838677T3 (pl) 2004-12-21 2010-02-26 Arena Pharm Inc Krystaliczne postacie agonisty chlorowodorku (R)-8-chloro-1-metylo-2,3,4,5-tetrahydro-1H-3-benzazepiny
BRPI0515862A2 (pt) 2004-12-23 2011-10-11 Arena Pharm Inc uso de fentermina e agonista seletivo do receptor de 5ht-2c na preparação de composições, composições moduladoras do receptor de 5ht-2c e forma de dosagem unitária compreendendo as mesmas
SG10201508066VA (en) 2006-04-03 2015-10-29 Arena Pharm Inc Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
CN101547892B (zh) 2006-12-05 2014-08-20 艾尼纳制药公司 制备(r)-8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的方法和其中间体
WO2009111004A1 (en) 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
WO2010148207A2 (en) 2009-06-18 2010-12-23 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
WO2011153206A1 (en) 2010-06-02 2011-12-08 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
WO2012030927A2 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
US8999970B2 (en) 2010-09-01 2015-04-07 Arena Pharmaceuticals, Inc. Administration of an anti-obesity compound to individuals with renal impairment
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
SG188361A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Non-hygroscopic salts of 5-ht2c agonists
UY34436A (es) 2012-10-09 2014-07-31 Arena Pharm Inc Metodo de control del peso

Also Published As

Publication number Publication date
AT277257B (de) 1969-12-29
DE1795132A1 (de) 1972-01-05
CH498122A (de) 1970-10-31
ES357247A1 (es) 1970-03-01
FR1598948A (xx) 1970-07-15
IL30458A (en) 1972-03-28
NL6811311A (xx) 1969-08-12
BE719631A (xx) 1969-02-17
IL30458A0 (en) 1968-09-26
GB1225053A (en) 1971-03-17

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