DK1227824T3 - Transplantations-/implantationsindretning og fremgangsmåde til fremstilling af den - Google Patents

Transplantations-/implantationsindretning og fremgangsmåde til fremstilling af den

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Publication number
DK1227824T3
DK1227824T3 DK00972527T DK00972527T DK1227824T3 DK 1227824 T3 DK1227824 T3 DK 1227824T3 DK 00972527 T DK00972527 T DK 00972527T DK 00972527 T DK00972527 T DK 00972527T DK 1227824 T3 DK1227824 T3 DK 1227824T3
Authority
DK
Denmark
Prior art keywords
chondrocytes
cells
cartilaginous tissue
mixing
immobilized
Prior art date
Application number
DK00972527T
Other languages
Danish (da)
English (en)
Inventor
Pierre Mainil-Varlet
Werner Mueller
Shawn P Grogan
Thomas Schaffner
Original Assignee
Zimmer Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zimmer Gmbh filed Critical Zimmer Gmbh
Application granted granted Critical
Publication of DK1227824T3 publication Critical patent/DK1227824T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
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    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
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    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
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    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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DK00972527T 1999-11-11 2000-11-13 Transplantations-/implantationsindretning og fremgangsmåde til fremstilling af den DK1227824T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99122460A EP1099443A1 (fr) 1999-11-11 1999-11-11 Dispositif pour greffe/implant et sa méthode de production

Publications (1)

Publication Number Publication Date
DK1227824T3 true DK1227824T3 (da) 2004-10-11

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DK00972527T DK1227824T3 (da) 1999-11-11 2000-11-13 Transplantations-/implantationsindretning og fremgangsmåde til fremstilling af den

Country Status (11)

Country Link
US (1) US8137689B1 (fr)
EP (2) EP1099443A1 (fr)
JP (1) JP2003513929A (fr)
AT (1) ATE268182T1 (fr)
AU (1) AU784185B2 (fr)
CA (1) CA2390834A1 (fr)
DE (1) DE60011284T2 (fr)
DK (1) DK1227824T3 (fr)
ES (1) ES2222242T3 (fr)
PT (1) PT1227824E (fr)
WO (1) WO2001034166A1 (fr)

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ATE220564T1 (de) 1997-08-14 2002-08-15 Sulzer Innotec Ag Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren
US7005127B2 (en) * 2002-03-29 2006-02-28 Tissuegene, Inc. Mixed-cell gene therapy
AU2004216551B2 (en) 2003-02-26 2008-09-18 Zimmer Orthobiologics, Inc. Preparation for repairing cartilage tissue, especially articular cartilage defects
US7067123B2 (en) * 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
CN101198588B (zh) * 2005-04-19 2013-04-24 瑟尔费斯罗季克斯公司 微粒体三酸甘油酯转运蛋白及载脂蛋白-b分泌的抑制剂
EP1764117A1 (fr) * 2005-09-20 2007-03-21 Zimmer GmbH Implant pour la réparation de défauts cartilagineux et son procédé de préparation
US7476339B2 (en) 2006-08-18 2009-01-13 Saint-Gobain Ceramics & Plastics, Inc. Highly filled thermoplastic composites
WO2011112822A2 (fr) * 2010-03-10 2011-09-15 University Of Florida Research Foundation. Inc. Dispositif thérapeutique implantable et procédés de fabrication

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US4627853A (en) 1985-05-29 1986-12-09 American Hospital Supply Corporation Method of producing prostheses for replacement of articular cartilage and prostheses so produced
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EP1227824A1 (fr) 2002-08-07
PT1227824E (pt) 2004-10-29
AU1124901A (en) 2001-06-06
EP1227824B1 (fr) 2004-06-02
DE60011284T2 (de) 2005-08-25
ATE268182T1 (de) 2004-06-15
US8137689B1 (en) 2012-03-20
DE60011284D1 (de) 2004-07-08
EP1099443A1 (fr) 2001-05-16
JP2003513929A (ja) 2003-04-15
AU784185B2 (en) 2006-02-16
CA2390834A1 (fr) 2001-05-17

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