DK1210112T3 - Vaccine mod HBV og HPV - Google Patents
Vaccine mod HBV og HPVInfo
- Publication number
- DK1210112T3 DK1210112T3 DK00960618T DK00960618T DK1210112T3 DK 1210112 T3 DK1210112 T3 DK 1210112T3 DK 00960618 T DK00960618 T DK 00960618T DK 00960618 T DK00960618 T DK 00960618T DK 1210112 T3 DK1210112 T3 DK 1210112T3
- Authority
- DK
- Denmark
- Prior art keywords
- hpv
- vaccine against
- against hbv
- hbv
- vaccine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9921147.6A GB9921147D0 (en) | 1999-09-07 | 1999-09-07 | Novel composition |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1210112T3 true DK1210112T3 (da) | 2006-08-14 |
Family
ID=10860521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00960618T DK1210112T3 (da) | 1999-09-07 | 2000-09-06 | Vaccine mod HBV og HPV |
Country Status (29)
Country | Link |
---|---|
US (2) | US7371390B2 (de) |
EP (2) | EP1210112B1 (de) |
JP (1) | JP4694745B2 (de) |
KR (1) | KR100782637B1 (de) |
CN (1) | CN1171637C (de) |
AR (1) | AR025503A1 (de) |
AT (2) | ATE414533T1 (de) |
AU (1) | AU765245B2 (de) |
BR (1) | BR0014172A (de) |
CA (1) | CA2381047C (de) |
CY (1) | CY1106091T1 (de) |
CZ (1) | CZ2002842A3 (de) |
DE (2) | DE60040879D1 (de) |
DK (1) | DK1210112T3 (de) |
ES (2) | ES2314816T3 (de) |
GB (1) | GB9921147D0 (de) |
GC (1) | GC0000202A (de) |
HK (1) | HK1048436B (de) |
HU (1) | HUP0202826A3 (de) |
IL (1) | IL148455A0 (de) |
MX (1) | MXPA02002483A (de) |
MY (1) | MY134860A (de) |
NO (1) | NO20021115L (de) |
NZ (1) | NZ517622A (de) |
PL (1) | PL353923A1 (de) |
PT (1) | PT1210112E (de) |
TR (1) | TR200200608T2 (de) |
WO (1) | WO2001017550A2 (de) |
ZA (1) | ZA200201834B (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US20060029617A1 (en) * | 1997-10-03 | 2006-02-09 | Charreyre Catherine E | Porcine circovirus and Helicobacter combination vaccines and methods of use |
FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
CA2773698C (en) | 1998-10-16 | 2015-05-19 | Glaxosmithkline Biologicals S.A. | Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof |
GB9921146D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
GB0206360D0 (en) * | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
GB0210682D0 (en) * | 2002-05-09 | 2002-06-19 | Glaxosmithkline Biolog Sa | Novel use |
ATE544466T1 (de) | 2002-10-29 | 2012-02-15 | Coley Pharm Group Inc | Verwendung von cpg oligonukleotide zur behandlung von hepatitis c virus infektion |
WO2004053104A2 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5’ cpg nucleic acids and methods of use |
KR100525321B1 (ko) * | 2002-12-13 | 2005-11-02 | 안웅식 | 파필로마바이러스 항원 단백질 및CpG-올리고데옥시뉴클레오타이드를 포함하는파필로마바이러스 유발 질환의 예방 또는 치료용 약제학적조성물 |
US7858098B2 (en) * | 2002-12-20 | 2010-12-28 | Glaxosmithkline Biologicals, S.A. | Vaccine |
US7758866B2 (en) * | 2004-06-16 | 2010-07-20 | Glaxosmithkline Biologicals, S.A. | Vaccine against HPV16 and HPV18 and at least another HPV type selected from HPV 31, 45 or 52 |
GB0413510D0 (en) * | 2004-06-16 | 2004-07-21 | Glaxosmithkline Biolog Sa | Vaccine |
JP2008502633A (ja) * | 2004-06-16 | 2008-01-31 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Hpv16およびhpv18ならびにhpv31、45または52から選ばれる少なくとも1つの別のhpv型に対するワクチン |
US7833707B2 (en) | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
HUE027837T2 (en) * | 2005-03-23 | 2016-11-28 | Glaxosmithkline Biologicals Sa | Adjuvant use of influenza virus and oil-in-water emulsion to induce CD4 T-cell and / or enhanced B-cell cellular response |
EA013326B1 (ru) * | 2005-04-26 | 2010-04-30 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
ES2572736T3 (es) | 2005-12-29 | 2016-06-02 | Boehringer Ingelheim Vetmedica, Inc. | Uso de una composición inmunógena para atenuar síntomas clínicos en cerdos |
CN102698263B (zh) | 2005-12-29 | 2016-07-06 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 多价pcv2免疫原性组合物和制备此类组合物的方法 |
EP1941903A1 (de) | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxe und Behandlung von PRDC |
EP1958644A1 (de) | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Vorbeugung und Behandlung von subklinischer PCVD |
US7829274B2 (en) | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
RU2509570C2 (ru) * | 2008-06-09 | 2014-03-20 | Бхарат Байотек Интернэшнл Лимитед | Вакцинная композиция, пригодная при инфекциях hpv и вирусом гепатита в, и способ ее получения |
NZ589755A (en) * | 2008-06-09 | 2013-04-26 | Bharat Biotech Int Ltd | Vaccine composition useful for hpv and hepatitis b infections and a method for preparing the same |
AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
US10058605B2 (en) * | 2012-05-09 | 2018-08-28 | Bharat Biotech International Limited | Vaccine combinations |
KR101347288B1 (ko) * | 2012-05-18 | 2014-01-06 | 안웅식 | 융합 폴리펩타이드 hpv 항원을 이용한 hpv 항체 스크리닝 키트 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992011291A1 (en) * | 1990-12-20 | 1992-07-09 | Smithkline Beecham Biologicals (S.A.) | Vaccines based on hepatitis b surface antigen |
MY111880A (en) * | 1992-03-27 | 2001-02-28 | Smithkline Beecham Biologicals S A | Hepatitis vaccines containing 3-0 deacylated monophosphoryl lipid a |
SG48309A1 (en) * | 1993-03-23 | 1998-04-17 | Smithkline Beecham Biolog | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid a |
GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
GB9620795D0 (en) * | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
AU753688B2 (en) * | 1997-03-10 | 2002-10-24 | Ottawa Civic Loeb Research Institute | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
DE69933200T2 (de) * | 1998-03-09 | 2007-02-22 | Glaxosmithkline Biologicals S.A. | Kombinierte impfstoffzusammensetzungen |
GB9921146D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
-
1999
- 1999-09-07 GB GBGB9921147.6A patent/GB9921147D0/en not_active Ceased
-
2000
- 2000-09-05 AR ARP000104637A patent/AR025503A1/es unknown
- 2000-09-05 MY MYPI20004084A patent/MY134860A/en unknown
- 2000-09-06 PL PL00353923A patent/PL353923A1/xx not_active IP Right Cessation
- 2000-09-06 AT AT06075535T patent/ATE414533T1/de not_active IP Right Cessation
- 2000-09-06 EP EP00960618A patent/EP1210112B1/de not_active Expired - Lifetime
- 2000-09-06 PT PT00960618T patent/PT1210112E/pt unknown
- 2000-09-06 EP EP06075535A patent/EP1731167B1/de not_active Expired - Lifetime
- 2000-09-06 DE DE60040879T patent/DE60040879D1/de not_active Expired - Lifetime
- 2000-09-06 BR BR0014172-0A patent/BR0014172A/pt not_active Application Discontinuation
- 2000-09-06 MX MXPA02002483A patent/MXPA02002483A/es active IP Right Grant
- 2000-09-06 AT AT00960618T patent/ATE323509T1/de not_active IP Right Cessation
- 2000-09-06 JP JP2001521338A patent/JP4694745B2/ja not_active Expired - Fee Related
- 2000-09-06 CA CA2381047A patent/CA2381047C/en not_active Expired - Fee Related
- 2000-09-06 CN CNB00815418XA patent/CN1171637C/zh not_active Expired - Fee Related
- 2000-09-06 WO PCT/EP2000/008728 patent/WO2001017550A2/en active IP Right Grant
- 2000-09-06 KR KR1020027003022A patent/KR100782637B1/ko not_active IP Right Cessation
- 2000-09-06 CZ CZ2002842A patent/CZ2002842A3/cs unknown
- 2000-09-06 AU AU72848/00A patent/AU765245B2/en not_active Ceased
- 2000-09-06 DK DK00960618T patent/DK1210112T3/da active
- 2000-09-06 IL IL14845500A patent/IL148455A0/xx unknown
- 2000-09-06 ES ES06075535T patent/ES2314816T3/es not_active Expired - Lifetime
- 2000-09-06 TR TR2002/00608T patent/TR200200608T2/xx unknown
- 2000-09-06 NZ NZ517622A patent/NZ517622A/en unknown
- 2000-09-06 DE DE60027440T patent/DE60027440T2/de not_active Expired - Lifetime
- 2000-09-06 ES ES00960618T patent/ES2261237T3/es not_active Expired - Lifetime
- 2000-09-06 HU HU0202826A patent/HUP0202826A3/hu unknown
- 2000-09-06 GC GCP2000893 patent/GC0000202A/en active
-
2002
- 2002-03-05 ZA ZA200201834A patent/ZA200201834B/xx unknown
- 2002-03-06 NO NO20021115A patent/NO20021115L/no not_active Application Discontinuation
- 2002-11-21 HK HK02108454.0A patent/HK1048436B/zh not_active IP Right Cessation
-
2004
- 2004-11-08 US US10/983,451 patent/US7371390B2/en not_active Expired - Fee Related
-
2006
- 2006-06-05 CY CY20061100714T patent/CY1106091T1/el unknown
-
2007
- 2007-12-17 US US11/957,677 patent/US20080118527A1/en not_active Abandoned
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