DK1165543T3 - Fremgangsmåde til fremstilling af [S-(R*,S*)]-G(B)-[[1-[1-oxo-3-(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinpropansyre og derivater deraf - Google Patents
Fremgangsmåde til fremstilling af [S-(R*,S*)]-G(B)-[[1-[1-oxo-3-(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinpropansyre og derivater derafInfo
- Publication number
- DK1165543T3 DK1165543T3 DK00916573T DK00916573T DK1165543T3 DK 1165543 T3 DK1165543 T3 DK 1165543T3 DK 00916573 T DK00916573 T DK 00916573T DK 00916573 T DK00916573 T DK 00916573T DK 1165543 T3 DK1165543 T3 DK 1165543T3
- Authority
- DK
- Denmark
- Prior art keywords
- piperidinyl
- oxo
- carbonyl
- propyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12567199P | 1999-03-22 | 1999-03-22 | |
| PCT/US2000/007462 WO2000056730A1 (en) | 1999-03-22 | 2000-03-21 | PROCESS FOR PREPARING [S-(R*,S*)] -β -[[[1-[1-OXO-3- (4-PIPERIDINYL) PROPYL] -3-PIPERIDINYL] CARBONYL] AMINO] -3- PYRIDINEPROPANOIC ACID AND DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1165543T3 true DK1165543T3 (da) | 2003-09-29 |
Family
ID=22420863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00916573T DK1165543T3 (da) | 1999-03-22 | 2000-03-21 | Fremgangsmåde til fremstilling af [S-(R*,S*)]-G(B)-[[1-[1-oxo-3-(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinpropansyre og derivater deraf |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US6515130B1 (enExample) |
| EP (1) | EP1165543B1 (enExample) |
| JP (1) | JP2002540108A (enExample) |
| KR (1) | KR20020019895A (enExample) |
| CN (1) | CN1351600A (enExample) |
| AT (1) | ATE242235T1 (enExample) |
| AU (1) | AU775413B2 (enExample) |
| BR (1) | BR0010652A (enExample) |
| CA (1) | CA2368024A1 (enExample) |
| CZ (1) | CZ20013431A3 (enExample) |
| DE (1) | DE60003169T2 (enExample) |
| DK (1) | DK1165543T3 (enExample) |
| ES (1) | ES2199805T3 (enExample) |
| HK (1) | HK1046272A1 (enExample) |
| HR (1) | HRP20010767A2 (enExample) |
| HU (1) | HUP0201262A3 (enExample) |
| MX (1) | MXPA01009615A (enExample) |
| PT (1) | PT1165543E (enExample) |
| SK (1) | SK13562001A3 (enExample) |
| UA (1) | UA67832C2 (enExample) |
| WO (1) | WO2000056730A1 (enExample) |
| YU (1) | YU74601A (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2367971A1 (en) | 1999-03-22 | 2000-09-28 | Ortho-Mcneil Pharmaceutical, Inc. | Synthesis of 3-amino-3-aryl propanoates |
| BR0212896A (pt) * | 2001-09-21 | 2004-10-13 | Sanofi Synthelabo | Derivados de 2-piridinil-6,7,8,9-tetrahidropirimido[1,2-a]pirimidin-4- ona e 7-piridinil-2,3dihidroimidazo[1,2-a] pirimidin-5(1h)ona substituìdos |
| HRP20170464T1 (hr) | 2011-08-17 | 2017-05-19 | Piramal Imaging Sa | Spojevi za vezanje na glikoprotein iib/iiia specifičan za trombocite i njihova upotreba u vizualiziranju ugrušaka |
| EP2956461A1 (en) | 2013-02-12 | 2015-12-23 | Bayer Pharma Aktiengesellschaft | Metal chelate compounds for binding to the platelet specific glycoprotein iib/iiia |
| EP2958894B8 (en) | 2013-02-20 | 2020-02-26 | Reuter Chemische Apparatenbau e.K. | Process for the preparation of enantiomerically enriched 3-aminopiperidine |
| US20160068486A1 (en) | 2013-04-22 | 2016-03-10 | Reuter Chemische Apparatebau Kg | Process for preparing enantiomerically enriched 3-hydroxymethylpiperidine |
| KR102548998B1 (ko) | 2020-03-31 | 2023-06-29 | 재단법인 아산사회복지재단 | 혈전영상을 위한 방사성의약품 및 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58243B1 (en) | 1983-12-07 | 1993-08-11 | Lonza Ag | A process for the preparation of optically-active 3-amino carboxylic acids |
| US5254573A (en) | 1991-10-15 | 1993-10-19 | Monsanto Company | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors |
| DE69429328T2 (de) | 1993-09-22 | 2002-06-13 | Fujisawa Pharmaceutical Co., Ltd. | N-(3-piperidinylcarbonyl)-b-alanin derivate als paf-antagonisten |
| US5770575A (en) * | 1994-03-16 | 1998-06-23 | Ortho Pharmaceutical Corporation | Nipecotic acid derivatives as antithrombotic compounds |
| KR19990087694A (ko) * | 1996-03-13 | 1999-12-27 | 후지야마 아키라 | 피브리노겐 수용체 길항제로서의 N-[(R)-１-{３-(４-피페리딜)프로피오닐-３-피페리딜카보닐]-２(S)-아세틸아미노-β-알라닌 |
| ES2320316T3 (es) * | 1996-05-01 | 2009-05-21 | Ortho-Mcneil Pharmaceutical, Inc. | Derivados carboxamida de pirrolidina, piperidina y hexahidroazepina utiles en el tratamiento de trastornos tromboticos. |
| US5840961A (en) | 1996-07-12 | 1998-11-24 | G. D. Searle & Co. | Asymmetric synthesis of chiral beta-amiNo acids |
| US6066651A (en) * | 1997-10-29 | 2000-05-23 | Ortho-Mcneil Pharmaceutical, Inc. | Orally-active nipecotamide glycolamide esters for the treatment of thrombosis disorders |
-
2000
- 2000-03-21 YU YU74601A patent/YU74601A/sh unknown
- 2000-03-21 UA UA2001096538A patent/UA67832C2/uk unknown
- 2000-03-21 DE DE60003169T patent/DE60003169T2/de not_active Expired - Fee Related
- 2000-03-21 KR KR1020017012100A patent/KR20020019895A/ko not_active Withdrawn
- 2000-03-21 CA CA002368024A patent/CA2368024A1/en not_active Abandoned
- 2000-03-21 AT AT00916573T patent/ATE242235T1/de not_active IP Right Cessation
- 2000-03-21 PT PT00916573T patent/PT1165543E/pt unknown
- 2000-03-21 HU HU0201262A patent/HUP0201262A3/hu unknown
- 2000-03-21 ES ES00916573T patent/ES2199805T3/es not_active Expired - Lifetime
- 2000-03-21 US US09/532,375 patent/US6515130B1/en not_active Expired - Lifetime
- 2000-03-21 BR BR0010652-6A patent/BR0010652A/pt not_active IP Right Cessation
- 2000-03-21 EP EP00916573A patent/EP1165543B1/en not_active Expired - Lifetime
- 2000-03-21 SK SK1356-2001A patent/SK13562001A3/sk unknown
- 2000-03-21 CN CN00807617A patent/CN1351600A/zh active Pending
- 2000-03-21 MX MXPA01009615A patent/MXPA01009615A/es unknown
- 2000-03-21 AU AU37661/00A patent/AU775413B2/en not_active Ceased
- 2000-03-21 WO PCT/US2000/007462 patent/WO2000056730A1/en not_active Ceased
- 2000-03-21 JP JP2000606591A patent/JP2002540108A/ja active Pending
- 2000-03-21 HR HR20010767A patent/HRP20010767A2/hr not_active Application Discontinuation
- 2000-03-21 CZ CZ20013431A patent/CZ20013431A3/cs unknown
- 2000-03-21 DK DK00916573T patent/DK1165543T3/da active
- 2000-03-21 HK HK02107463.1A patent/HK1046272A1/zh unknown
-
2002
- 2002-02-22 US US10/081,289 patent/US20020137937A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE242235T1 (de) | 2003-06-15 |
| EP1165543A1 (en) | 2002-01-02 |
| CN1351600A (zh) | 2002-05-29 |
| CZ20013431A3 (cs) | 2003-04-16 |
| UA67832C2 (uk) | 2004-07-15 |
| SK13562001A3 (sk) | 2002-08-06 |
| AU775413B2 (en) | 2004-07-29 |
| ES2199805T3 (es) | 2004-03-01 |
| HUP0201262A2 (en) | 2002-08-28 |
| US6515130B1 (en) | 2003-02-04 |
| MXPA01009615A (es) | 2003-07-21 |
| KR20020019895A (ko) | 2002-03-13 |
| YU74601A (sh) | 2004-05-12 |
| AU3766100A (en) | 2000-10-09 |
| US20020137937A1 (en) | 2002-09-26 |
| BR0010652A (pt) | 2002-07-16 |
| EP1165543B1 (en) | 2003-06-04 |
| HUP0201262A3 (en) | 2003-12-29 |
| DE60003169T2 (de) | 2005-10-27 |
| PT1165543E (pt) | 2003-10-31 |
| HU0201262D0 (enExample) | 2002-05-29 |
| DE60003169D1 (de) | 2003-07-10 |
| WO2000056730A1 (en) | 2000-09-28 |
| HRP20010767A2 (en) | 2002-12-31 |
| JP2002540108A (ja) | 2002-11-26 |
| HK1046272A1 (zh) | 2003-01-03 |
| CA2368024A1 (en) | 2000-09-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200738667A (en) | Preparation method for dioxan-2-ylalkylcarbamate derivatives and intermediate thereof | |
| NO20076006L (no) | Acetylenderivater | |
| DE60137273D1 (de) | Verfahren zur Herstellung von 4-Phenoxy chinolin Derivaten | |
| DE60316728D1 (de) | Phosphonium- und imidazoliumsalze und verfahren zu deren herstellung | |
| IL189466A0 (en) | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | |
| SE9904652D0 (sv) | Novel Compounds | |
| EP1724262A4 (en) | 1- (2H) -ISOCHINOLONDERIVAT | |
| IL152848A0 (en) | 1,2-dihydropyridine derivatives, pharmaceutical compositions containing the same and methods for the production thereof | |
| CY1106743T1 (el) | Μεθοδος παρασκευης θειαμεθοξαμης | |
| IL183373A0 (en) | 3-[2-(3-acylamino-2-oxo-2h-pyridin-1-yl)-acetylamino]-4-oxo-pentanoic acid derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof | |
| ATE544744T1 (de) | Verfahren zur herstellung von benzoesaure derivaten | |
| BR0209901A (pt) | Processos para a sìntese de derivados de 2,3-dihidro-1,4-dioxino-[2,3-f] quinolina | |
| CA2395969A1 (en) | Novel tetrahydropyridines, method for the preparation thereof and pharmaceutical compositions containing them | |
| MXPA01009615A (es) | Procedimiento para la preparacion de acido [s -(r*s*)] -°-[[[1[1- oxo-3 -(4-piperidinil) propil]3 -piperidini] carbonil] amino] -3-piridinil] carbonil] amino] -3-piridinpropanoico, y derivados del mismo. | |
| WO2001044207A3 (fr) | Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2 4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant | |
| EA200300458A1 (ru) | Новые соединения аминотриазолона, способ их получения и фармацевтические композиции, содержащие их | |
| DK1206452T3 (da) | Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser | |
| WO2004039776A3 (en) | A process for the preparation of benzyl 2-oxo-4- (heteroaryl) dithio-alpha-isoprenyl-1- azetidineazetate derivatives | |
| WO2004009585A3 (fr) | Derives d'acyloxypyrrolidine et leur utilisation en tant que ligands des recepteurs v1b et v1a de avp | |
| NO20035313L (no) | Fremgangsmåte for fremstilling av tialzol PPAR-ligand og polymorfer derav | |
| ATE309198T1 (de) | Fungizide mit einer fluorovinyl-oder fluoropropenyloxyphenyloxim-einheit und ein verfahren zu ihrer herstellung. | |
| DK1113009T3 (da) | Fremgangsmåde til fremstilling af sulfonylaminocarbonyltriazolinonsalte | |
| DK1265908T3 (da) | Fremgangsmåde til fremstilling af derivater af 9-deoxo-8a-aza-(8a-alkyl)-8a-homoerythromycin A ud fra 9-deoxo-9(Z)-hydroxyiminoerythromycin A | |
| EA200100155A2 (ru) | Новые производные 6-амино или 6-гидразиносульфонил-3-хинолинилфосфоновой кислоты, способ их получения и содержащие их фармацевтические композиции | |
| DE60306361D1 (de) | Verfahren zur herstellung von benazeprilhydrochloride |