DK1162272T3 - Frembringelse af immunreaktioner med prostataspecifikt antigen (SPA) - Google Patents
Frembringelse af immunreaktioner med prostataspecifikt antigen (SPA)Info
- Publication number
- DK1162272T3 DK1162272T3 DK01113517T DK01113517T DK1162272T3 DK 1162272 T3 DK1162272 T3 DK 1162272T3 DK 01113517 T DK01113517 T DK 01113517T DK 01113517 T DK01113517 T DK 01113517T DK 1162272 T3 DK1162272 T3 DK 1162272T3
- Authority
- DK
- Denmark
- Prior art keywords
- psa
- host
- virus vector
- specific antigen
- additional
- Prior art date
Links
- 102000007066 Prostate-Specific Antigen Human genes 0.000 title abstract 10
- 108010072866 Prostate-Specific Antigen Proteins 0.000 title abstract 10
- 230000008105 immune reaction Effects 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 3
- 239000013598 vector Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 230000024932 T cell mediated immunity Effects 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000028996 humoral immune response Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000737 periodic effect Effects 0.000 abstract 1
- 239000013603 viral vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/500,306 US6165460A (en) | 1995-07-10 | 1995-07-10 | Generation of immune responses to prostate-specific antigen (PSA) |
PCT/US1996/010837 WO1997003203A2 (en) | 1995-07-10 | 1996-06-26 | Generation of immune responses to prostate-specific antigen (psa) |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1162272T3 true DK1162272T3 (da) | 2009-03-09 |
Family
ID=23988841
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96923417T DK0840791T3 (da) | 1995-07-10 | 1996-06-26 | Frembringelse af immunreaktioner mod prostataspecifikt antigen (PSA) |
DK01113517T DK1162272T3 (da) | 1995-07-10 | 1996-06-26 | Frembringelse af immunreaktioner med prostataspecifikt antigen (SPA) |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96923417T DK0840791T3 (da) | 1995-07-10 | 1996-06-26 | Frembringelse af immunreaktioner mod prostataspecifikt antigen (PSA) |
Country Status (11)
Country | Link |
---|---|
US (2) | US6165460A (da) |
EP (2) | EP1162272B8 (da) |
JP (3) | JP4633867B2 (da) |
AT (2) | ATE413459T1 (da) |
CA (1) | CA2226436C (da) |
DE (2) | DE69618601T2 (da) |
DK (2) | DK0840791T3 (da) |
ES (2) | ES2320089T3 (da) |
HK (1) | HK1042518B (da) |
PT (2) | PT840791E (da) |
WO (1) | WO1997003203A2 (da) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6699475B1 (en) * | 1987-09-02 | 2004-03-02 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
US6165460A (en) * | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
US6946133B1 (en) * | 1996-03-20 | 2005-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Prostate specific antigen oligo-epitope peptide |
US20010036928A1 (en) * | 1996-04-22 | 2001-11-01 | Chamberlain Ronald S. | Heterologous boosting immunizations |
EP0954593A1 (en) * | 1996-07-25 | 1999-11-10 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
US20030235557A1 (en) | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
EP1497320B1 (en) | 2001-11-14 | 2011-08-24 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | New gene expressed in prostate cancer and methods of use |
BR0311720A (pt) * | 2002-06-11 | 2005-03-01 | Merck Patent Gmbh | Método para mapear e eliminar epitopos de células t |
DE10230893A1 (de) * | 2002-06-26 | 2004-01-15 | Dr. Fischer Ag | Verfahren zur Eigenschaftsbestimmung und/oder Klassifikation von zirkulierenden Macrophagen und/oder peripheren blutmononuclearen Zellen sowie Analyseanordnung zur Durchführung des Verfahrens |
WO2004056977A1 (en) * | 2002-12-13 | 2004-07-08 | Aventis Pasteur, Inc. | Production of alvac on avian embryonic stem cells |
WO2005005465A2 (en) * | 2003-07-08 | 2005-01-20 | Board Of Regents, University Of Texas System | Methods and compositions to enhance immune responses via recall antigens |
NZ545438A (en) * | 2003-08-21 | 2008-08-29 | Virax Dev Pty Ltd | Poxvirus vector encoding prostate specific antigens for treatment of prostate cancer |
CA2570563A1 (en) * | 2004-06-15 | 2006-09-28 | Centocor, Inc. | Method for screening agents against human prostate disease |
CA2612225A1 (en) * | 2005-06-21 | 2007-01-04 | Cyto Pulse Sciences, Inc. | Methods and compositions relating to a vaccine against prostate cancer |
EP1994409A2 (en) | 2006-03-14 | 2008-11-26 | Oregon Health and Science University | Methods for producing an immune response to tuberculosis |
NZ704295A (en) | 2006-12-27 | 2016-06-24 | Harvard College | Compositions and methods for the treatment of infections and tumors |
AU2008221383B2 (en) | 2007-02-28 | 2012-09-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
RU2499606C2 (ru) * | 2007-10-18 | 2013-11-27 | Бавэариан Нордик Инк. | Применение mva (модифицированный вирус коровьей оспы анкара) для лечения рака простаты |
US8691502B2 (en) | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
WO2010050913A1 (en) * | 2008-10-31 | 2010-05-06 | The Brigham And Women's Hospital, Inc. | Vaccination with poxvirus vectors via mechanical epidermal disruption |
AU2009319701B2 (en) | 2008-11-28 | 2014-10-09 | Dana-Farber Cancer Institute, Inc. | Methods for the treatment of infections and tumors |
US8664183B2 (en) | 2009-02-27 | 2014-03-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | SPANX-B polypeptides and their use |
US8961989B2 (en) | 2009-11-20 | 2015-02-24 | Oregon Health & Science University | Methods for producing an immune response to tuberculosis |
US9804163B2 (en) | 2010-08-06 | 2017-10-31 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Biomarkers for prostate cancer and methods for their detection |
WO2014043518A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Brachyury protein, non-poxvirus non-yeast vectors encoding brachyury protein, and their use |
JPWO2014097762A1 (ja) * | 2012-12-20 | 2017-01-12 | 国立大学法人 熊本大学 | 高病原性トリインフルエンザに対する抗体 |
WO2015175340A1 (en) | 2014-05-13 | 2015-11-19 | Bavarian Nordic, Inc. | Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and a monoclonal antibody against tim-3 |
JP5917626B2 (ja) * | 2014-07-28 | 2016-05-18 | トレムアールエックス, インコーポレイテッド | 機械的表皮破壊を介したポックスウイルスベクターによるワクチン接種 |
CN107849117B (zh) | 2015-06-05 | 2022-08-26 | 艾比欧公司 | 用于治疗纤维化的内皮抑素片段和变体 |
US10550164B2 (en) | 2015-08-03 | 2020-02-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Brachyury deletion mutants, non-yeast vectors encoding Brachyury deletion mutants, and their use |
US20190183870A1 (en) | 2016-01-05 | 2019-06-20 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Combination of histone deacetylase inhibitor and immunotherapy |
WO2017136342A1 (en) | 2016-02-02 | 2017-08-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Fulvestrant for inducing immune-mediated cytotoxic lysis of cancer cells |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5833975A (en) * | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
WO1989001973A2 (en) * | 1987-09-02 | 1989-03-09 | Applied Biotechnology, Inc. | Recombinant pox virus for immunization against tumor-associated antigens |
US5093258A (en) * | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
GB9105383D0 (en) * | 1991-03-14 | 1991-05-01 | Immunology Ltd | An immunotherapeutic for cervical cancer |
ES2206446T3 (es) * | 1991-05-06 | 2004-05-16 | The Government Of The Usa As Represented By The Secretary Of Department Of Health And Human Services | Virus recombinante que expresa un antigeno carcinoembrionico y metodos de uso del mismo. |
ES2276390T3 (es) * | 1992-11-05 | 2007-06-16 | Sloan-Kettering Institute For Cancer Research | Antigeno de membrana especifico de la prostata. |
DE69434475T2 (de) * | 1993-08-11 | 2006-05-18 | Jenner Technologies, Tiburon | Impfstoff gegen prostatakrebs |
FR2710536B1 (fr) * | 1993-09-29 | 1995-12-22 | Transgene Sa | Usage anti-cancéreux d'un vecteur viral comportant un gène modulateur de la réponse immunitaire et/ou inflammatoire. |
EP0652014A1 (en) * | 1993-11-10 | 1995-05-10 | National Institute Of Immunology | Treatment of prostatic hypertrophy |
ZA941645B (en) * | 1994-03-09 | 1995-01-13 | South To South Co Operation In | Antibodies specifically reactive against human prostate specific antigen. |
EP0725139A3 (en) * | 1995-02-03 | 1997-11-26 | Bayer Corporation | Recombinant prostate-specific antigen and its use as an immunoassay calibrator |
US6165460A (en) * | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
-
1995
- 1995-07-10 US US08/500,306 patent/US6165460A/en not_active Expired - Lifetime
-
1996
- 1996-06-26 PT PT96923417T patent/PT840791E/pt unknown
- 1996-06-26 WO PCT/US1996/010837 patent/WO1997003203A2/en active IP Right Grant
- 1996-06-26 JP JP50583497A patent/JP4633867B2/ja not_active Expired - Lifetime
- 1996-06-26 PT PT01113517T patent/PT1162272E/pt unknown
- 1996-06-26 DE DE69618601T patent/DE69618601T2/de not_active Expired - Lifetime
- 1996-06-26 EP EP01113517A patent/EP1162272B8/en not_active Expired - Lifetime
- 1996-06-26 EP EP96923417A patent/EP0840791B1/en not_active Expired - Lifetime
- 1996-06-26 ES ES01113517T patent/ES2320089T3/es not_active Expired - Lifetime
- 1996-06-26 DK DK96923417T patent/DK0840791T3/da active
- 1996-06-26 AT AT01113517T patent/ATE413459T1/de active
- 1996-06-26 DE DE69637738T patent/DE69637738D1/de not_active Expired - Lifetime
- 1996-06-26 CA CA002226436A patent/CA2226436C/en not_active Expired - Fee Related
- 1996-06-26 AT AT96923417T patent/ATE212058T1/de active
- 1996-06-26 DK DK01113517T patent/DK1162272T3/da active
- 1996-06-26 ES ES96923417T patent/ES2172669T3/es not_active Expired - Lifetime
-
2000
- 2000-10-20 US US09/693,121 patent/US7598225B1/en not_active Expired - Lifetime
-
2002
- 2002-05-11 HK HK02103565.7A patent/HK1042518B/zh not_active IP Right Cessation
-
2006
- 2006-02-15 JP JP2006038681A patent/JP2006197938A/ja not_active Withdrawn
-
2008
- 2008-06-13 JP JP2008156031A patent/JP2008285492A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US7598225B1 (en) | 2009-10-06 |
ES2172669T3 (es) | 2002-10-01 |
ATE212058T1 (de) | 2002-02-15 |
PT840791E (pt) | 2002-06-28 |
US6165460A (en) | 2000-12-26 |
EP1162272A3 (en) | 2004-07-14 |
JP2006197938A (ja) | 2006-08-03 |
EP0840791B1 (en) | 2002-01-16 |
CA2226436A1 (en) | 1997-01-30 |
DE69618601D1 (de) | 2002-02-21 |
HK1042518B (zh) | 2009-04-17 |
CA2226436C (en) | 2006-11-07 |
DE69618601T2 (de) | 2002-08-08 |
JPH11509199A (ja) | 1999-08-17 |
HK1042518A1 (en) | 2002-08-16 |
EP0840791A2 (en) | 1998-05-13 |
DE69637738D1 (de) | 2008-12-18 |
WO1997003203A3 (en) | 1997-04-17 |
ATE413459T1 (de) | 2008-11-15 |
EP1162272B1 (en) | 2008-11-05 |
EP1162272A2 (en) | 2001-12-12 |
JP2008285492A (ja) | 2008-11-27 |
WO1997003203A2 (en) | 1997-01-30 |
JP4633867B2 (ja) | 2011-02-16 |
EP1162272B8 (en) | 2010-03-10 |
ES2320089T3 (es) | 2009-05-19 |
PT1162272E (pt) | 2009-02-16 |
DK0840791T3 (da) | 2002-03-18 |
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