NO963508L - Urease-basert vaksine og behandling av Helicobacter-infeksjon - Google Patents
Urease-basert vaksine og behandling av Helicobacter-infeksjonInfo
- Publication number
- NO963508L NO963508L NO963508A NO963508A NO963508L NO 963508 L NO963508 L NO 963508L NO 963508 A NO963508 A NO 963508A NO 963508 A NO963508 A NO 963508A NO 963508 L NO963508 L NO 963508L
- Authority
- NO
- Norway
- Prior art keywords
- urease
- helicobacter infection
- treatment
- based vaccine
- helicobacter
- Prior art date
Links
- 206010019375 Helicobacter infections Diseases 0.000 title abstract 3
- 108010046334 Urease Proteins 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000589989 Helicobacter Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Fremgangsmåte til å fremkalle hos en pattedyrvert en beskyttende immunrespons på Helicobacter-infeksjon og behandling av Helicobacter-infeksjon ved administrering til verten av en immunogent effektiv mengde av en Helicobacter- urease eller urease-underenheter som antigen. Vaksine- blandinger tilveiebringes også.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/200,346 US6290962B1 (en) | 1992-11-03 | 1994-02-23 | Urease-based vaccine and treatment for helicobacter infection |
PCT/US1995/002202 WO1995022987A1 (en) | 1994-02-23 | 1995-02-23 | Urease-based vaccine and treatment for helicobacter infection |
Publications (2)
Publication Number | Publication Date |
---|---|
NO963508D0 NO963508D0 (no) | 1996-08-22 |
NO963508L true NO963508L (no) | 1996-10-21 |
Family
ID=22741337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO963508A NO963508L (no) | 1994-02-23 | 1996-08-22 | Urease-basert vaksine og behandling av Helicobacter-infeksjon |
Country Status (15)
Country | Link |
---|---|
US (2) | US6290962B1 (no) |
EP (1) | EP0751786A4 (no) |
JP (1) | JPH09509661A (no) |
AU (1) | AU694195C (no) |
BR (1) | BR9506884A (no) |
CA (1) | CA2184057A1 (no) |
CZ (1) | CZ250396A3 (no) |
FI (1) | FI963281A (no) |
HU (1) | HUT75374A (no) |
NO (1) | NO963508L (no) |
NZ (1) | NZ282535A (no) |
OA (1) | OA10372A (no) |
PL (1) | PL179149B1 (no) |
SK (1) | SK109496A3 (no) |
WO (1) | WO1995022987A1 (no) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6406703B1 (en) | 1993-07-27 | 2002-06-18 | Csl Limited | Treatment of H. pylori associated gastroduodenal disease |
KR100333113B1 (ko) * | 1993-07-27 | 2002-11-27 | 시에스엘 리미티드 | 헬리코박터피롤리관련위십이지장질환의치료방법 |
AU723063B2 (en) * | 1995-04-28 | 2000-08-17 | Oravax, Inc | Multimeric, recombinant urease vaccine |
CN1201395A (zh) * | 1995-10-09 | 1998-12-09 | 科泰克斯国际有限公司 | 治疗幽门螺杆菌感染的方法 |
GB2307987A (en) * | 1995-12-06 | 1997-06-11 | Univ Manchester | Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto |
SE9600647D0 (sv) * | 1996-02-21 | 1996-02-21 | Bror Morein | Ny användning |
BR9708679A (pt) * | 1996-04-15 | 2000-01-04 | Anton Mayr | Uso de indutores de pox, e, processo para tratamento auxiliar de pacientes submetidos à quimioterapia ou radioterapia. |
EP0935965A4 (en) * | 1996-04-23 | 2002-01-23 | Toray Industries | SUBSTANCE AGAINST PYLORI |
NZ333250A (en) * | 1996-06-10 | 2000-05-26 | Thomas Boren | Helicobacter pylori blood group antigen binding adhesion protein |
US6248551B1 (en) * | 1997-03-28 | 2001-06-19 | Institut Pasteur | Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides |
US20020026035A1 (en) * | 1997-04-01 | 2002-02-28 | Harold Kleanthous | Helicobacter ghpo 1360 and ghpo 750 polypeptides and corresponding polynucleotide molecules |
JP3430853B2 (ja) | 1997-04-11 | 2003-07-28 | 株式会社ゲン・コーポレーション | 胃炎、胃潰瘍および十二指腸潰瘍の予防剤並びに治療剤 |
FR2762788B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter pour usage par voie systemique sous-diaphragmatique |
CA2287976A1 (fr) * | 1997-04-30 | 1998-11-05 | Bruno Guy | Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1 |
FR2762787B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1 |
US20030158396A1 (en) * | 1997-07-29 | 2003-08-21 | Harold Kleanthous | Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome |
US6599509B2 (en) * | 1997-09-02 | 2003-07-29 | Massachusetts Institute Of Technology | Compositions and methods comprising helicobacter antigens for treatment and prevention of inflammatory bowel disease |
US5985631A (en) * | 1997-09-12 | 1999-11-16 | Oravax-Merieux Co. | Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease |
US20020151462A1 (en) * | 1998-02-19 | 2002-10-17 | Ling Lissolo | Helicobacter pylori membrane proteins |
GB9807721D0 (en) * | 1998-04-08 | 1998-06-10 | Chiron Spa | Antigen |
US6585975B1 (en) * | 1998-04-30 | 2003-07-01 | Acambis, Inc. | Use of Salmonella vectors for vaccination against helicobacter infection |
CA2335487A1 (en) | 1998-06-19 | 1999-12-23 | Merieux Oravax | Lt and ct in parenteral immunization methods against helicobacter infection |
US7384640B1 (en) * | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
US7041296B1 (en) * | 1999-11-12 | 2006-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of treating inflammatory bowel disease using cholera toxin B subunit |
GB9928196D0 (en) * | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
CA2351110A1 (en) * | 2000-07-17 | 2002-01-17 | Akzo Nobel N.V. | Helicobacter felis vaccine |
US7285281B2 (en) | 2001-06-07 | 2007-10-23 | Wyeth Holdings Corporation | Mutant forms of cholera holotoxin as an adjuvant |
JP2005508143A (ja) * | 2001-06-07 | 2005-03-31 | ワイス・ホールデイングス・コーポレーシヨン | アジュバントとしてのコレラホロトキシンの突然変異形 |
BR0214279A (pt) * | 2001-11-19 | 2005-12-20 | Becton Dickinson Co | Composições farmacêuticas em forma particulada |
US20030118658A1 (en) * | 2001-12-21 | 2003-06-26 | Trogolo Jeffrey A. | High aspect ratio encapsulated inorganic antimicrobial additive for controlled release |
US7357949B2 (en) * | 2001-12-21 | 2008-04-15 | Agion Technologies Inc. | Encapsulated inorganic antimicrobial additive for controlled release |
FR2837835B1 (fr) * | 2002-03-29 | 2007-06-22 | Maria Urdaci | Souche bacillus subtilis cu1, son utilisation comme agent immunomodulateur du systeme immunitaire et vaccin recombinant vivant contre h. pylori la contenant |
CN1212126C (zh) * | 2002-07-09 | 2005-07-27 | 中国科学院长春应用化学研究所 | 纳米羟基磷灰石补钙剂 |
JP2004041084A (ja) * | 2002-07-11 | 2004-02-12 | Japan Science & Technology Corp | ヘリコバクター・ピロリ菌に対するワクチン用ペプチド、それをコードする遺伝子、その遺伝子が導入された形質転換体、及びそれらの利用方法 |
US7264800B2 (en) | 2002-07-18 | 2007-09-04 | Helix Biopharma Corporation | Method and composition for inhibiting cancer cell growth |
PT1530482E (pt) * | 2002-07-18 | 2014-01-15 | Helix Biopharma Corp | Utilização de urease para inibição de crescimento de células cancerigenas |
US20040109905A1 (en) * | 2002-09-18 | 2004-06-10 | Debasis Bagchi | Method and composition of anthocyanin-rich berry extracts that prevents or inhibits angiogenesis and helicobacter pylori and acts as a powerful antioxidant that provides various health benefits |
US20070258901A1 (en) * | 2004-08-04 | 2007-11-08 | Ursula Boschert | Capsules Containing Transiently Transfected Cells, Method for Preparing Same and Uses Thereof |
US8029777B2 (en) | 2004-08-13 | 2011-10-04 | Marshall Barry J | Helicobacter system and uses thereof |
JP2008509168A (ja) * | 2004-08-13 | 2008-03-27 | マーシャル,バリー,ジェー. | 細菌デリバリシステム |
CN101611143B (zh) * | 2006-11-10 | 2015-01-14 | 翁德克控股有限公司 | 将肽递送入胃粘膜的方法和装置 |
PL218700B1 (pl) | 2012-03-29 | 2015-01-30 | Gdański Univ Medyczny | Doustna szczepionka zawierająca przetrwalniki Bacillus subtilis oraz jej zastosowanie do immunizacji przeciwko Helicobacter pylori |
CN103461685B (zh) * | 2012-06-07 | 2014-10-22 | 中国农业科学院北京畜牧兽医研究所 | 瘤胃脲酶抗原组合物及其制备方法和应用及瘤胃脲酶抗原蛋白的应用 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5268278A (en) * | 1984-03-30 | 1993-12-07 | Istituto Farmacologico Serono S.P.A. | Genetic expression of somatostatin as hybrid polypeptide |
US4879213A (en) * | 1986-12-05 | 1989-11-07 | Scripps Clinic And Research Foundation | Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse |
US5268276A (en) * | 1988-09-16 | 1993-12-07 | Jan Holmgren | Recombinant systems for expression of cholera B-sub-unit with the aid of foreign promoters and/or leader peptides |
FR2637612B1 (fr) * | 1988-10-06 | 1993-09-10 | Pasteur Institut | Sequences de nucleotides codant pour une proteine a activite ureasique |
US5443832A (en) | 1990-04-16 | 1995-08-22 | Institut Swisse De Recherches Experimentales Sur Le Cancer | Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response |
ATE273021T1 (de) | 1992-02-26 | 2004-08-15 | Univ Vanderbilt | Gereinigtes vakuolisierendes toxin aus helicobacter pylori und methoden zu dessen verwendung |
US5859219A (en) | 1992-02-26 | 1999-01-12 | Vanderbilt University | Purified vacuolating toxin from Helicobacter pylori and methods to use same |
JP3368902B2 (ja) * | 1992-03-02 | 2003-01-20 | カイロン エセ.ピー.アー. | ワクチンおよび診断に有用なHelicobacterpyloriタンパク質 |
MX9301706A (es) * | 1992-04-13 | 1994-05-31 | Oravax Inc | Composicion de vacuna para el tratamiento de la infeccion por helicobacter. |
ES2111625T3 (es) * | 1992-07-06 | 1998-03-16 | Nestle Sa | Agente antigastritis. |
US5733740A (en) | 1992-10-13 | 1998-03-31 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma |
US5403924A (en) | 1992-10-13 | 1995-04-04 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration |
US5972336A (en) | 1992-11-03 | 1999-10-26 | Oravax Merieux Co. | Urease-based vaccine against helicobacter infection |
KR100333113B1 (ko) | 1993-07-27 | 2002-11-27 | 시에스엘 리미티드 | 헬리코박터피롤리관련위십이지장질환의치료방법 |
AUPM612494A0 (en) * | 1994-06-08 | 1994-06-30 | Csl Limited | Treatment or prevention of helicobacter infection |
DE19521312A1 (de) * | 1995-06-12 | 1996-12-19 | Max Planck Gesellschaft | Verfahren zur Identifizierung sekretorischer Gene aus Helicobacter pylori |
DE19521314A1 (de) * | 1995-06-12 | 1996-12-19 | Max Planck Gesellschaft | Adhärenzgen aus Helicobacter pylori und davon codiertes Polypeptid |
DE19535321A1 (de) * | 1995-09-22 | 1997-03-27 | Max Planck Gesellschaft | Neues Adhäsin aus Helicobacter pylori |
GB2307987A (en) * | 1995-12-06 | 1997-06-11 | Univ Manchester | Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto |
FR2745186B1 (fr) * | 1996-02-26 | 1998-12-31 | Torossian Fernand Narbey | Complexe immunomodulateur et ses utilisations pour le traitement et la prevention des recidives des affections par helicobacter |
WO1997038110A2 (en) * | 1996-04-05 | 1997-10-16 | Kieta Holding S.A. | Compositions and methods relating to drug discovery and detection and treatment of gastrointestinal diseases |
US20030023066A1 (en) * | 1996-11-14 | 2003-01-30 | Rainer Haas | Helicobacter polypeptides and corresponding polynucleotide molecules |
US20030069404A1 (en) * | 1996-11-14 | 2003-04-10 | Rainer Haas | Helicobacter antigens and corresponding DNA fragments |
US6248551B1 (en) * | 1997-03-28 | 2001-06-19 | Institut Pasteur | Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides |
US5985631A (en) * | 1997-09-12 | 1999-11-16 | Oravax-Merieux Co. | Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease |
WO2001083531A1 (en) * | 2000-04-27 | 2001-11-08 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for identifying helicobacter antigens |
-
1994
- 1994-02-23 US US08/200,346 patent/US6290962B1/en not_active Expired - Fee Related
-
1995
- 1995-02-23 PL PL95316007A patent/PL179149B1/pl not_active IP Right Cessation
- 1995-02-23 HU HU9602310A patent/HUT75374A/hu unknown
- 1995-02-23 AU AU19681/95A patent/AU694195C/en not_active Withdrawn - After Issue
- 1995-02-23 NZ NZ282535A patent/NZ282535A/en unknown
- 1995-02-23 BR BR9506884A patent/BR9506884A/pt not_active Application Discontinuation
- 1995-02-23 EP EP95912583A patent/EP0751786A4/en not_active Withdrawn
- 1995-02-23 CZ CZ962503A patent/CZ250396A3/cs unknown
- 1995-02-23 SK SK1094-96A patent/SK109496A3/sk unknown
- 1995-02-23 JP JP7522429A patent/JPH09509661A/ja active Pending
- 1995-02-23 WO PCT/US1995/002202 patent/WO1995022987A1/en not_active Application Discontinuation
- 1995-02-23 CA CA002184057A patent/CA2184057A1/en not_active Abandoned
-
1996
- 1996-08-22 FI FI963281A patent/FI963281A/fi unknown
- 1996-08-22 NO NO963508A patent/NO963508L/no not_active Application Discontinuation
- 1996-08-23 OA OA60879A patent/OA10372A/fr unknown
-
2001
- 2001-09-18 US US09/955,739 patent/US20030007980A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1995022987A1 (en) | 1995-08-31 |
AU694195C (en) | 2001-07-19 |
EP0751786A4 (en) | 1999-12-29 |
SK109496A3 (en) | 1997-07-09 |
FI963281A (fi) | 1996-10-22 |
AU694195B2 (en) | 1998-07-16 |
PL316007A1 (en) | 1996-12-23 |
AU1968195A (en) | 1995-09-11 |
BR9506884A (pt) | 1997-08-19 |
HU9602310D0 (en) | 1996-10-28 |
NO963508D0 (no) | 1996-08-22 |
US20030007980A1 (en) | 2003-01-09 |
PL179149B1 (pl) | 2000-07-31 |
NZ282535A (en) | 2001-03-30 |
OA10372A (en) | 2001-11-14 |
CZ250396A3 (en) | 1996-12-11 |
EP0751786A1 (en) | 1997-01-08 |
JPH09509661A (ja) | 1997-09-30 |
HUT75374A (en) | 1997-05-28 |
CA2184057A1 (en) | 1995-08-31 |
US6290962B1 (en) | 2001-09-18 |
FI963281A0 (fi) | 1996-08-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |