NO963508D0 - Ureasebasert vaksine og behandling av Heliobacter infeksjon - Google Patents

Ureasebasert vaksine og behandling av Heliobacter infeksjon

Info

Publication number
NO963508D0
NO963508D0 NO963508A NO963508A NO963508D0 NO 963508 D0 NO963508 D0 NO 963508D0 NO 963508 A NO963508 A NO 963508A NO 963508 A NO963508 A NO 963508A NO 963508 D0 NO963508 D0 NO 963508D0
Authority
NO
Norway
Prior art keywords
urea
treatment
based vaccine
heliobacter infection
heliobacter
Prior art date
Application number
NO963508A
Other languages
English (en)
Other versions
NO963508L (no
Inventor
Pierre Michetti
Irene Corthesy-Theulaz
Andre Blum
Catherine Davin
Rainer Haas
Jean-Pierre Kraehenbuhl
Emilia Saraga
Original Assignee
Oravax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oravax Inc filed Critical Oravax Inc
Publication of NO963508D0 publication Critical patent/NO963508D0/no
Publication of NO963508L publication Critical patent/NO963508L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO963508A 1994-02-23 1996-08-22 Urease-basert vaksine og behandling av Helicobacter-infeksjon NO963508L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/200,346 US6290962B1 (en) 1992-11-03 1994-02-23 Urease-based vaccine and treatment for helicobacter infection
PCT/US1995/002202 WO1995022987A1 (en) 1994-02-23 1995-02-23 Urease-based vaccine and treatment for helicobacter infection

Publications (2)

Publication Number Publication Date
NO963508D0 true NO963508D0 (no) 1996-08-22
NO963508L NO963508L (no) 1996-10-21

Family

ID=22741337

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963508A NO963508L (no) 1994-02-23 1996-08-22 Urease-basert vaksine og behandling av Helicobacter-infeksjon

Country Status (15)

Country Link
US (2) US6290962B1 (no)
EP (1) EP0751786A4 (no)
JP (1) JPH09509661A (no)
AU (1) AU694195C (no)
BR (1) BR9506884A (no)
CA (1) CA2184057A1 (no)
CZ (1) CZ250396A3 (no)
FI (1) FI963281A (no)
HU (1) HUT75374A (no)
NO (1) NO963508L (no)
NZ (1) NZ282535A (no)
OA (1) OA10372A (no)
PL (1) PL179149B1 (no)
SK (1) SK109496A3 (no)
WO (1) WO1995022987A1 (no)

Families Citing this family (43)

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Publication number Priority date Publication date Assignee Title
US6406703B1 (en) 1993-07-27 2002-06-18 Csl Limited Treatment of H. pylori associated gastroduodenal disease
KR100333113B1 (ko) * 1993-07-27 2002-11-27 시에스엘 리미티드 헬리코박터피롤리관련위십이지장질환의치료방법
NZ307017A (en) * 1995-04-28 1999-07-29 Oravax Inc Vaccine containing multimeric complexes of helicobacter urease, composition of antigen (from gastroduodenal pathogen) and antibiotic, antisecretory agent, and/or bismuth salt
BR9611033A (pt) * 1995-10-09 1999-12-28 Cortecs International Limited Processos para tratar infecção por h.pylori, em um mamífero e para converter a forma coccóide de h. pylori em cultura na forma em espiral e a forma em espiral de h.pylori em cultura na forma coccóide, formulação farmaceutica e uso de um agente capaz de induzir a forma coccóide de h.pylori
GB2307987A (en) * 1995-12-06 1997-06-11 Univ Manchester Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto
SE9600647D0 (sv) * 1996-02-21 1996-02-21 Bror Morein Ny användning
DK0885013T3 (da) * 1996-04-15 2001-11-05 Anton Prof Dr Med Vet Dr Mayr Anvendelse af multipotente paramunitetsinducere fra svækkede, ikke-immunogene poxvirus eller parapoxvirus til fremstilling af lægemidler
CA2252467A1 (en) * 1996-04-23 1997-10-30 Toray Industries, Inc. Antipylori agent
AU726429B2 (en) * 1996-06-10 2000-11-09 Thomas Boren Helicobacter pylori adhesin binding group antigen
US6248551B1 (en) * 1997-03-28 2001-06-19 Institut Pasteur Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides
US20020026035A1 (en) * 1997-04-01 2002-02-28 Harold Kleanthous Helicobacter ghpo 1360 and ghpo 750 polypeptides and corresponding polynucleotide molecules
JP3430853B2 (ja) * 1997-04-11 2003-07-28 株式会社ゲン・コーポレーション 胃炎、胃潰瘍および十二指腸潰瘍の予防剤並びに治療剤
FR2762788B1 (fr) * 1997-04-30 2000-10-06 Pasteur Merieux Serums Vacc Composition vaccinale anti-helicobacter pour usage par voie systemique sous-diaphragmatique
JP2002505665A (ja) * 1997-04-30 2002-02-19 メリュー・オラバックス Ｔｈ１型アジュバントを含有する抗ヘリコバクターワクチン組成物
FR2762787B1 (fr) * 1997-04-30 2000-10-06 Pasteur Merieux Serums Vacc Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1
US20030158396A1 (en) * 1997-07-29 2003-08-21 Harold Kleanthous Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome
US6599509B2 (en) 1997-09-02 2003-07-29 Massachusetts Institute Of Technology Compositions and methods comprising helicobacter antigens for treatment and prevention of inflammatory bowel disease
US5985631A (en) * 1997-09-12 1999-11-16 Oravax-Merieux Co. Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease
US20020151462A1 (en) * 1998-02-19 2002-10-17 Ling Lissolo Helicobacter pylori membrane proteins
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
US6585975B1 (en) * 1998-04-30 2003-07-01 Acambis, Inc. Use of Salmonella vectors for vaccination against helicobacter infection
CA2335487A1 (en) 1998-06-19 1999-12-23 Merieux Oravax Lt and ct in parenteral immunization methods against helicobacter infection
US7384640B1 (en) * 1999-09-30 2008-06-10 Wyeth Holdings Corporation Mutant cholera holotoxin as an adjuvant
US7041296B1 (en) * 1999-11-12 2006-05-09 The United States Of America As Represented By The Department Of Health And Human Services Methods of treating inflammatory bowel disease using cholera toxin B subunit
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
CA2351110A1 (en) * 2000-07-17 2002-01-17 Akzo Nobel N.V. Helicobacter felis vaccine
KR100877258B1 (ko) * 2001-06-07 2009-01-12 와이어쓰 홀딩스 코포레이션 보조제로서 콜레라 홀로톡신의 돌연변이체 형태
JP2004535187A (ja) * 2001-06-07 2004-11-25 ワイス・ホールデイングス・コーポレーシヨン アジュバントとしてのコレラホロトキシンの突然変異形
CN1607941A (zh) * 2001-11-19 2005-04-20 贝克顿迪肯森公司 粒状药物组合物
US7357949B2 (en) * 2001-12-21 2008-04-15 Agion Technologies Inc. Encapsulated inorganic antimicrobial additive for controlled release
US20030118658A1 (en) * 2001-12-21 2003-06-26 Trogolo Jeffrey A. High aspect ratio encapsulated inorganic antimicrobial additive for controlled release
FR2837835B1 (fr) * 2002-03-29 2007-06-22 Maria Urdaci Souche bacillus subtilis cu1, son utilisation comme agent immunomodulateur du systeme immunitaire et vaccin recombinant vivant contre h. pylori la contenant
CN1212126C (zh) * 2002-07-09 2005-07-27 中国科学院长春应用化学研究所 纳米羟基磷灰石补钙剂
JP2004041084A (ja) * 2002-07-11 2004-02-12 Japan Science & Technology Corp ヘリコバクター・ピロリ菌に対するワクチン用ペプチド、それをコードする遺伝子、その遺伝子が導入された形質転換体、及びそれらの利用方法
US7264800B2 (en) 2002-07-18 2007-09-04 Helix Biopharma Corporation Method and composition for inhibiting cancer cell growth
TR200500108T2 (tr) * 2002-07-18 2005-04-21 Helix Biopharma Corp. Kanser Hücresi Gelişiminin İnhibe Edilmesinde Üreaz Kullanımı
US20040109905A1 (en) * 2002-09-18 2004-06-10 Debasis Bagchi Method and composition of anthocyanin-rich berry extracts that prevents or inhibits angiogenesis and helicobacter pylori and acts as a powerful antioxidant that provides various health benefits
WO2006016238A2 (en) * 2004-08-04 2006-02-16 Applied Research Systems Ars Holding N.V. Capsules containing transfected cells, method for preparing the same and uses thereof for immunization and vaccination
US8029777B2 (en) * 2004-08-13 2011-10-04 Marshall Barry J Helicobacter system and uses thereof
CN102078622A (zh) 2004-08-13 2011-06-01 巴里.J.马沙尔 细菌递送系统
CA2668984A1 (en) * 2006-11-10 2008-05-15 Barry J. Marshall Methods and devices for the delivery of peptides into the gastric mucosa
PL218700B1 (pl) 2012-03-29 2015-01-30 Gdański Univ Medyczny Doustna szczepionka zawierająca przetrwalniki Bacillus subtilis oraz jej zastosowanie do immunizacji przeciwko Helicobacter pylori
CN103461685B (zh) * 2012-06-07 2014-10-22 中国农业科学院北京畜牧兽医研究所 瘤胃脲酶抗原组合物及其制备方法和应用及瘤胃脲酶抗原蛋白的应用

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US5443832A (en) 1990-04-16 1995-08-22 Institut Swisse De Recherches Experimentales Sur Le Cancer Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
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ATE161181T1 (de) * 1992-07-06 1998-01-15 Nestle Sa Lactobacillus acidophilus enthaltende antigastritis-mittel
US5403924A (en) 1992-10-13 1995-04-04 Vanderbilt University Taga gene and methods for detecting predisposition to peptic ulceration
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US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
KR100333113B1 (ko) 1993-07-27 2002-11-27 시에스엘 리미티드 헬리코박터피롤리관련위십이지장질환의치료방법
AUPM612494A0 (en) * 1994-06-08 1994-06-30 Csl Limited Treatment or prevention of helicobacter infection
DE19521314A1 (de) * 1995-06-12 1996-12-19 Max Planck Gesellschaft Adhärenzgen aus Helicobacter pylori und davon codiertes Polypeptid
DE19521312A1 (de) * 1995-06-12 1996-12-19 Max Planck Gesellschaft Verfahren zur Identifizierung sekretorischer Gene aus Helicobacter pylori
DE19535321A1 (de) * 1995-09-22 1997-03-27 Max Planck Gesellschaft Neues Adhäsin aus Helicobacter pylori
GB2307987A (en) * 1995-12-06 1997-06-11 Univ Manchester Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto
FR2745186B1 (fr) * 1996-02-26 1998-12-31 Torossian Fernand Narbey Complexe immunomodulateur et ses utilisations pour le traitement et la prevention des recidives des affections par helicobacter
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US20030069404A1 (en) * 1996-11-14 2003-04-10 Rainer Haas Helicobacter antigens and corresponding DNA fragments
US6248551B1 (en) * 1997-03-28 2001-06-19 Institut Pasteur Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides
US5985631A (en) * 1997-09-12 1999-11-16 Oravax-Merieux Co. Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease
ATE345354T1 (de) * 2000-04-27 2006-12-15 Max Planck Gesellschaft Methode zur identifizierung von helicobacter antigenen

Also Published As

Publication number Publication date
HUT75374A (en) 1997-05-28
OA10372A (en) 2001-11-14
NO963508L (no) 1996-10-21
FI963281A (fi) 1996-10-22
EP0751786A1 (en) 1997-01-08
AU694195C (en) 2001-07-19
PL179149B1 (pl) 2000-07-31
HU9602310D0 (en) 1996-10-28
CZ250396A3 (en) 1996-12-11
NZ282535A (en) 2001-03-30
US6290962B1 (en) 2001-09-18
JPH09509661A (ja) 1997-09-30
AU1968195A (en) 1995-09-11
FI963281A0 (fi) 1996-08-22
EP0751786A4 (en) 1999-12-29
BR9506884A (pt) 1997-08-19
SK109496A3 (en) 1997-07-09
PL316007A1 (en) 1996-12-23
CA2184057A1 (en) 1995-08-31
US20030007980A1 (en) 2003-01-09
WO1995022987A1 (en) 1995-08-31
AU694195B2 (en) 1998-07-16

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