DK1157100T3 - Oxaloacetathydrolase-defekte svampeværtsceller - Google Patents
Oxaloacetathydrolase-defekte svampeværtscellerInfo
- Publication number
- DK1157100T3 DK1157100T3 DK00904859T DK00904859T DK1157100T3 DK 1157100 T3 DK1157100 T3 DK 1157100T3 DK 00904859 T DK00904859 T DK 00904859T DK 00904859 T DK00904859 T DK 00904859T DK 1157100 T3 DK1157100 T3 DK 1157100T3
- Authority
- DK
- Denmark
- Prior art keywords
- host cells
- defective
- fungal host
- oxaloacetate hydrolase
- nucleic acid
- Prior art date
Links
- 230000002538 fungal effect Effects 0.000 title 1
- KHPXUQMNIQBQEV-UHFFFAOYSA-N oxaloacetic acid Chemical compound OC(=O)CC(=O)C(O)=O KHPXUQMNIQBQEV-UHFFFAOYSA-N 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 108010054497 oxaloacetase Proteins 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199900231 | 1999-02-22 | ||
| EP00904859A EP1157100B1 (en) | 1999-02-22 | 2000-02-18 | Oxaloacetate hydrolase deficient fungal host cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1157100T3 true DK1157100T3 (da) | 2006-05-29 |
Family
ID=8091215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00904859T DK1157100T3 (da) | 1999-02-22 | 2000-02-18 | Oxaloacetathydrolase-defekte svampeværtsceller |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1157100B1 (enExample) |
| JP (2) | JP4741082B2 (enExample) |
| CN (1) | CN1195058C (enExample) |
| AT (1) | ATE315638T1 (enExample) |
| AU (1) | AU2658200A (enExample) |
| DE (1) | DE60025467T2 (enExample) |
| DK (1) | DK1157100T3 (enExample) |
| WO (1) | WO2000050576A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1195058C (zh) * | 1999-02-22 | 2005-03-30 | 诺维信公司 | 草酰乙酸水解酶缺陷型真菌宿主细胞 |
| US6544765B1 (en) | 1999-02-22 | 2003-04-08 | Novozymes, A/S | Oxaloacetate hydrolase deficient fungal host cells |
| US20060127976A1 (en) * | 2003-02-05 | 2006-06-15 | Wenzel Thibaut J | Use of oxalate deficient aspergillus niger strains for producing a polypeptide |
| EP1613761B1 (en) | 2003-03-31 | 2009-09-02 | Novozymes Inc. | Methods for producing biological substances in enzyme-deficient mutants of aspergillus niger |
| DK1786908T3 (da) * | 2004-08-18 | 2010-06-07 | Bayer Cropscience Ag | Planter med forøget plastidisk aktivitet af stivelsesphosphorylerende R3-enzym |
| EP2423315B1 (en) | 2006-06-29 | 2015-01-07 | DSM IP Assets B.V. | A method for achieving improved polypeptide expression |
| MX346700B (es) | 2009-03-10 | 2017-03-28 | Dsm Ip Assets Bv | Metodo para mejorar el rendimiento de un polipeptido. |
| DK2406372T3 (da) | 2009-03-10 | 2017-11-27 | Dsm Ip Assets Bv | Prægastrisk esterase og derivater deraf |
| CN102414323B (zh) | 2009-04-22 | 2015-07-08 | 帝斯曼知识产权资产管理有限公司 | 用于生产感兴趣的重组多肽的方法 |
| CA2768608A1 (en) | 2009-07-22 | 2011-01-27 | Dsm Ip Assets B.V. | Improved host cell for the production of a compound of interest |
| BR112014016587A2 (pt) * | 2012-01-05 | 2020-10-27 | Novartis Ag | células fúngicas filamentosas deficientes de protease e métodos de uso das mesmas |
| JP6468561B2 (ja) | 2012-07-19 | 2019-02-13 | ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. | AgsE欠損株 |
| US11396665B2 (en) | 2015-01-06 | 2022-07-26 | Dsm Ip Assets B.V. | CRISPR-CAS system for a filamentous fungal host cell |
| ES2815628T3 (es) | 2015-02-20 | 2021-03-30 | Roal Oy | Métodos para controlar la producción de proteasas |
| EP3596199A1 (en) | 2017-03-13 | 2020-01-22 | DSM IP Assets B.V. | Zinc binuclear cluster transcriptional regulator-deficient strain |
| CN110791439B (zh) * | 2019-10-10 | 2022-04-19 | 天津科技大学 | 一株基因工程构建发酵生产苹果酸的重组黑曲霉菌株及应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1195058C (zh) * | 1999-02-22 | 2005-03-30 | 诺维信公司 | 草酰乙酸水解酶缺陷型真菌宿主细胞 |
-
2000
- 2000-02-18 CN CNB008041679A patent/CN1195058C/zh not_active Expired - Fee Related
- 2000-02-18 AT AT00904859T patent/ATE315638T1/de not_active IP Right Cessation
- 2000-02-18 DE DE60025467T patent/DE60025467T2/de not_active Expired - Lifetime
- 2000-02-18 WO PCT/DK2000/000067 patent/WO2000050576A1/en not_active Ceased
- 2000-02-18 JP JP2000601140A patent/JP4741082B2/ja not_active Expired - Fee Related
- 2000-02-18 DK DK00904859T patent/DK1157100T3/da active
- 2000-02-18 AU AU26582/00A patent/AU2658200A/en not_active Abandoned
- 2000-02-18 EP EP00904859A patent/EP1157100B1/en not_active Expired - Lifetime
-
2010
- 2010-12-24 JP JP2010287753A patent/JP2011101651A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1157100B1 (en) | 2006-01-11 |
| CN1341149A (zh) | 2002-03-20 |
| WO2000050576A1 (en) | 2000-08-31 |
| JP2002536993A (ja) | 2002-11-05 |
| DE60025467D1 (de) | 2006-04-06 |
| EP1157100A1 (en) | 2001-11-28 |
| JP2011101651A (ja) | 2011-05-26 |
| DE60025467T2 (de) | 2006-09-21 |
| AU2658200A (en) | 2000-09-14 |
| JP4741082B2 (ja) | 2011-08-03 |
| ATE315638T1 (de) | 2006-02-15 |
| CN1195058C (zh) | 2005-03-30 |
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