DK1128811T3 - Lægemiddelleveringsindretning, især til levering af progestiner og estrogener - Google Patents

Lægemiddelleveringsindretning, især til levering af progestiner og estrogener

Info

Publication number
DK1128811T3
DK1128811T3 DK99954020T DK99954020T DK1128811T3 DK 1128811 T3 DK1128811 T3 DK 1128811T3 DK 99954020 T DK99954020 T DK 99954020T DK 99954020 T DK99954020 T DK 99954020T DK 1128811 T3 DK1128811 T3 DK 1128811T3
Authority
DK
Denmark
Prior art keywords
progestins
estrogens
delivery
delivery device
drug delivery
Prior art date
Application number
DK99954020T
Other languages
Danish (da)
English (en)
Inventor
Tommi Markkula
Juha Ala-Sorvari
Matti Lehtinen
Jarkko Ruohonen
Harri Jukarainen
Original Assignee
Schering Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Oy filed Critical Schering Oy
Application granted granted Critical
Publication of DK1128811T3 publication Critical patent/DK1128811T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99954020T 1998-11-12 1999-10-26 Lægemiddelleveringsindretning, især til levering af progestiner og estrogener DK1128811T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/190,606 US6063395A (en) 1998-11-12 1998-11-12 Drug delivery device especially for the delivery of progestins and estrogens

Publications (1)

Publication Number Publication Date
DK1128811T3 true DK1128811T3 (da) 2004-09-27

Family

ID=22702031

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99954020T DK1128811T3 (da) 1998-11-12 1999-10-26 Lægemiddelleveringsindretning, især til levering af progestiner og estrogener

Country Status (30)

Country Link
US (1) US6063395A (cs)
EP (1) EP1128811B1 (cs)
JP (1) JP2002529493A (cs)
KR (1) KR100621426B1 (cs)
CN (1) CN1168439C (cs)
AR (1) AR021152A1 (cs)
AT (1) ATE267004T1 (cs)
AU (1) AU760302B2 (cs)
BG (1) BG65042B1 (cs)
BR (1) BR9915326B1 (cs)
CA (1) CA2351068C (cs)
CO (1) CO5271704A1 (cs)
CZ (1) CZ301609B6 (cs)
DE (1) DE69917477T2 (cs)
DK (1) DK1128811T3 (cs)
EE (1) EE05506B1 (cs)
ES (1) ES2221454T3 (cs)
HK (1) HK1041814B (cs)
HU (1) HU226113B1 (cs)
ID (1) ID29190A (cs)
IL (2) IL142523A0 (cs)
NO (1) NO332168B1 (cs)
NZ (1) NZ511216A (cs)
PE (1) PE20001041A1 (cs)
PL (1) PL194876B1 (cs)
PT (1) PT1128811E (cs)
RU (1) RU2226387C2 (cs)
SK (1) SK286730B6 (cs)
WO (1) WO2000028968A1 (cs)
ZA (1) ZA200103298B (cs)

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* Cited by examiner, † Cited by third party
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US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
US20060110424A1 (en) * 2000-03-24 2006-05-25 Lyles Mark B Ceramic and metal compositions
US7011841B2 (en) * 2000-03-24 2006-03-14 Mark B. Lyles High density porous materials
AU2001258442A1 (en) * 2000-05-10 2001-11-20 Leiras Oy Drug delivery device, especially for the delivery of levonorgestrel
US6299894B1 (en) 2000-05-10 2001-10-09 Leiras Oy Drug delivery device, especially for the delivery of gestodene
ES2253423T3 (es) * 2000-08-23 2006-06-01 Akzo Nobel N.V. Formulacion de un ester de testosterona para uso humano.
DE20015416U1 (de) 2000-09-06 2000-12-14 Bachmann, Karl-Heinz, 78667 Villingendorf Intrauterine Vorrichtung mit einem oder mehreren Pharmakadepots und integrierten Stellmitteln zur Variation der Abgabedosis
AU2002210580A1 (en) * 2000-10-20 2002-04-29 Leiras Oy Drug delivery system
US20040247674A1 (en) * 2001-08-31 2004-12-09 Timo Haapakumpu Drug delivery system
EP1494646B2 (en) * 2002-03-27 2017-10-04 Warner Chilcott (Ireland) Limited Intravaginal matrix drug delivery devices
WO2004037318A2 (en) * 2002-10-22 2004-05-06 The Biomerix Corporation Method and system for intravesicular delivery of therapeutic agents
EP1438942A1 (en) * 2003-01-17 2004-07-21 Schering Oy An otorhinological drug delivery device
JP2007521843A (ja) 2003-05-15 2007-08-09 バイオメリクス コーポレーション 網状化エラストマー系マトリックス、その製造、及び移植可能な装置における使用
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
EP2594259A1 (en) 2004-08-04 2013-05-22 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
US7862552B2 (en) * 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
KR101420988B1 (ko) 2005-10-13 2014-07-17 신세스 게엠바하 약물-함침 용기
US8303536B2 (en) * 2007-08-30 2012-11-06 Sunstorm Research Corp. Implantable delivery device
PL2062569T3 (pl) * 2007-11-22 2011-10-31 Bayer Oy Dopochwowy układ dostarczania leku
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
CA2709712C (en) 2007-12-20 2016-05-10 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
BRPI0905946B8 (pt) 2008-02-04 2021-05-25 Ferring Bv anel intravaginal monolítico e processo para a produção de um anel intravaginal monolítico
US10028858B2 (en) 2011-07-11 2018-07-24 Medicines360 Intrauterine systems, IUD insertion devices, and related methods and kits therefor
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
USD718435S1 (en) 2012-05-30 2014-11-25 Medicines360 Intrauterine insertion device
US10188426B2 (en) 2013-02-06 2019-01-29 Mark SILLENDER Embryo transfer catheter and method
WO2014121332A1 (en) 2013-02-06 2014-08-14 Sillender Mark Therapeutic substance transfer catheter and method
CN105555328B (zh) 2013-06-21 2019-01-11 德普伊新特斯产品公司 膜及制造方法
WO2016180764A1 (en) 2015-05-13 2016-11-17 Bayer Oy A long acting drug delivery device and its use in contraception
GB2555373A (en) * 2016-08-23 2018-05-02 Reproductive Medicine And Gynaecology Associates Ltd Implant
AU2018340266A1 (en) * 2017-09-27 2020-03-05 Bayer Oy A method for modifying release of a therapeutically active agent from an elastomeric matrix
US11571328B2 (en) 2018-04-09 2023-02-07 Medicines360 IUD insertion devices
US20200261258A1 (en) 2019-02-19 2020-08-20 Medicines360 Devices, systems, methods and kits for insertion and removal of iuds
US11938140B2 (en) 2022-05-26 2024-03-26 Insigna Inc. Non-surgical prevention of boar taint and aggressive behavior
WO2023230619A1 (en) * 2022-05-26 2023-11-30 Insigna Inc. Prevention of estrus in sow and ruminants

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US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
CH657779A5 (de) * 1982-10-05 1986-09-30 Sandoz Ag Galenische zusammensetzungen enthaltend calcitonin.
US5011692A (en) * 1985-12-28 1991-04-30 Sumitomo Pharmaceuticals Company, Limited Sustained pulsewise release pharmaceutical preparation
IT8702928A0 (it) * 1987-07-22 1987-07-22 Alga Di Giudici Angelamaria & Friggitrice con cestello rotante secondo un asse orizzontale.
ES2054784T3 (es) * 1987-08-08 1994-08-16 Akzo Nv Un metodo para la fabricacion de un implante.
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
CA2079452C (en) * 1990-04-02 1997-04-15 Donald Carroll Roe A particulate, absorbent, polymeric compositions containing interparticle crosslinked aggregates
JPH07216233A (ja) * 1992-09-21 1995-08-15 Toray Dow Corning Silicone Co Ltd フルオロシリコーンゴム組成物
US6117442A (en) * 1998-11-12 2000-09-12 Leiras Oy Drug delivery device, especially for the delivery of androgens

Also Published As

Publication number Publication date
BR9915326B1 (pt) 2013-10-22
BG65042B1 (bg) 2007-01-31
PE20001041A1 (es) 2000-10-14
ZA200103298B (en) 2001-10-25
EE200100256A (et) 2002-12-16
NO20012047L (no) 2001-06-28
KR100621426B1 (ko) 2006-09-13
HUP0104037A2 (hu) 2002-04-29
ATE267004T1 (de) 2004-06-15
US6063395A (en) 2000-05-16
BG105501A (en) 2001-12-29
JP2002529493A (ja) 2002-09-10
AU760302B2 (en) 2003-05-08
HUP0104037A3 (en) 2003-04-28
SK5132001A3 (en) 2001-11-06
EE05506B1 (et) 2012-02-15
HK1041814A1 (en) 2002-07-26
CA2351068C (en) 2008-09-02
DE69917477D1 (de) 2004-06-24
HU226113B1 (en) 2008-04-28
CO5271704A1 (es) 2003-04-30
KR20010075700A (ko) 2001-08-09
NO20012047D0 (no) 2001-04-26
IL142523A (en) 2006-06-11
EP1128811B1 (en) 2004-05-19
SK286730B6 (sk) 2009-04-06
CZ20011569A3 (cs) 2001-10-17
CA2351068A1 (en) 2000-05-25
EP1128811A1 (en) 2001-09-05
NO332168B1 (no) 2012-07-09
AU1048800A (en) 2000-06-05
ID29190A (id) 2001-08-09
RU2226387C2 (ru) 2004-04-10
DE69917477T2 (de) 2005-06-02
CN1168439C (zh) 2004-09-29
PT1128811E (pt) 2004-09-30
NZ511216A (en) 2002-09-27
PL348113A1 (en) 2002-05-06
BR9915326A (pt) 2001-10-09
ES2221454T3 (es) 2004-12-16
HK1041814B (zh) 2005-04-29
IL142523A0 (en) 2002-03-10
CZ301609B6 (cs) 2010-04-28
WO2000028968A1 (en) 2000-05-25
CN1326337A (zh) 2001-12-12
AR021152A1 (es) 2002-06-12
PL194876B1 (pl) 2007-07-31

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