CO5271704A1 - Dispositivo de suministro de farmacos, especialmente para el suministro de progestinas y estrogenos - Google Patents

Dispositivo de suministro de farmacos, especialmente para el suministro de progestinas y estrogenos

Info

Publication number
CO5271704A1
CO5271704A1 CO99067023A CO99067023A CO5271704A1 CO 5271704 A1 CO5271704 A1 CO 5271704A1 CO 99067023 A CO99067023 A CO 99067023A CO 99067023 A CO99067023 A CO 99067023A CO 5271704 A1 CO5271704 A1 CO 5271704A1
Authority
CO
Colombia
Prior art keywords
supply
strogens
pharmacos
progestines
elastomer
Prior art date
Application number
CO99067023A
Other languages
English (en)
Inventor
Tommi Markkula
Harri Jukarainen
Matti Lehtinen
Ruohonen Jarkko
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of CO5271704A1 publication Critical patent/CO5271704A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Nanotechnology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La presente invención se relaciona con un dispositivo de suministro de fármacos por vía subcutánea, intrauterina, intravaginal o transdérmica para la liberación controlada de un agente terapéuticamente activo durante un período de tiempo prolongado, comprendiendo dicho dispositivo: - Un núcleo que comprende dicho agente terapéuticamente activo, y - Una membrana que incluye en su interior dicho núcleo, en donde dicha membrana está hecha de un elastómero, caracterizado porque el elastómero es un elastómero basado en siloxano que comprende grupos 3,3,3-trifluoropropilo unidos a los átomos de Si de las unidades de sixolano.
CO99067023A 1998-11-12 1999-10-22 Dispositivo de suministro de farmacos, especialmente para el suministro de progestinas y estrogenos CO5271704A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/190,606 US6063395A (en) 1998-11-12 1998-11-12 Drug delivery device especially for the delivery of progestins and estrogens

Publications (1)

Publication Number Publication Date
CO5271704A1 true CO5271704A1 (es) 2003-04-30

Family

ID=22702031

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99067023A CO5271704A1 (es) 1998-11-12 1999-10-22 Dispositivo de suministro de farmacos, especialmente para el suministro de progestinas y estrogenos

Country Status (30)

Country Link
US (1) US6063395A (es)
EP (1) EP1128811B1 (es)
JP (1) JP2002529493A (es)
KR (1) KR100621426B1 (es)
CN (1) CN1168439C (es)
AR (1) AR021152A1 (es)
AT (1) ATE267004T1 (es)
AU (1) AU760302B2 (es)
BG (1) BG65042B1 (es)
BR (1) BR9915326B1 (es)
CA (1) CA2351068C (es)
CO (1) CO5271704A1 (es)
CZ (1) CZ301609B6 (es)
DE (1) DE69917477T2 (es)
DK (1) DK1128811T3 (es)
EE (1) EE05506B1 (es)
ES (1) ES2221454T3 (es)
HK (1) HK1041814B (es)
HU (1) HU226113B1 (es)
ID (1) ID29190A (es)
IL (2) IL142523A0 (es)
NO (1) NO332168B1 (es)
NZ (1) NZ511216A (es)
PE (1) PE20001041A1 (es)
PL (1) PL194876B1 (es)
PT (1) PT1128811E (es)
RU (1) RU2226387C2 (es)
SK (1) SK286730B6 (es)
WO (1) WO2000028968A1 (es)
ZA (1) ZA200103298B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
US20060110424A1 (en) * 2000-03-24 2006-05-25 Lyles Mark B Ceramic and metal compositions
EP1272440A2 (en) * 2000-03-24 2003-01-08 Mark B. Lyles High density porous materials
US6299894B1 (en) 2000-05-10 2001-10-09 Leiras Oy Drug delivery device, especially for the delivery of gestodene
AU2001258442A1 (en) * 2000-05-10 2001-11-20 Leiras Oy Drug delivery device, especially for the delivery of levonorgestrel
ATE311201T1 (de) * 2000-08-23 2005-12-15 Akzo Nobel Nv Testosteron-ester formulierung zur anwendung am menschen
DE20015416U1 (de) 2000-09-06 2000-12-14 Bachmann, Karl-Heinz, 78667 Villingendorf Intrauterine Vorrichtung mit einem oder mehreren Pharmakadepots und integrierten Stellmitteln zur Variation der Abgabedosis
AU2002210580A1 (en) * 2000-10-20 2002-04-29 Leiras Oy Drug delivery system
WO2003017971A1 (en) * 2001-08-31 2003-03-06 Schering Oy Drug delivery system
ES2388731T5 (es) * 2002-03-27 2018-01-19 Warner Chilcott (Ireland) Limited Dispositivos de administración de fármacos mediante una matriz intravaginal
EP1553899A4 (en) * 2002-10-22 2006-10-25 METHOD AND SYSTEM FOR INTRAVASCULAR DELIVERY OF THERAPEUTIC AGENTS
EP1438942A1 (en) * 2003-01-17 2004-07-21 Schering Oy An otorhinological drug delivery device
CA2525792C (en) 2003-05-15 2015-10-13 Biomerix Corporation Reticulated elastomeric matrices, their manufacture and use in implantable devices
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
WO2006078320A2 (en) 2004-08-04 2006-07-27 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
US7862552B2 (en) * 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
JP5137841B2 (ja) * 2005-10-13 2013-02-06 シンセス ゲーエムベーハー 薬物含浸容器
WO2009029958A2 (en) * 2007-08-30 2009-03-05 Sunstorm Research Corporation Implantable delivery device
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
ATE508734T1 (de) * 2007-11-22 2011-05-15 Bayer Oy System zur vaginalen freisetzung
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
DK2249757T3 (en) 2008-02-04 2017-10-16 Ferring Bv Monolithic vaginal rings comprising progesterone and methods of preparation and use thereof.
US10028858B2 (en) 2011-07-11 2018-07-24 Medicines360 Intrauterine systems, IUD insertion devices, and related methods and kits therefor
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
EP2953558B1 (en) 2013-02-06 2019-08-28 Sillender, Mark Embryo transfer catheter
AU2014214537B2 (en) 2013-02-06 2019-01-03 Mark SILLENDER Therapeutic substance transfer catheter and method
US20160144067A1 (en) 2013-06-21 2016-05-26 DePuy Synthes Products, Inc. Films and methods of manufacture
EP3294300A1 (en) * 2015-05-13 2018-03-21 Bayer Oy A long acting drug delivery device and its use in contraception
GB2555373A (en) * 2016-08-23 2018-05-02 Reproductive Medicine And Gynaecology Associates Ltd Implant
JOP20200067A1 (ar) * 2017-09-27 2020-04-27 Bayer Oy طريقة لتعديل اطلاق عامل فعال علاجياً من مادة أساس لدنة
US11571328B2 (en) 2018-04-09 2023-02-07 Medicines360 IUD insertion devices
US20200261258A1 (en) 2019-02-19 2020-08-20 Medicines360 Devices, systems, methods and kits for insertion and removal of iuds
US11938140B2 (en) 2022-05-26 2024-03-26 Insigna Inc. Non-surgical prevention of boar taint and aggressive behavior
WO2023230619A1 (en) * 2022-05-26 2023-11-30 Insigna Inc. Prevention of estrus in sow and ruminants

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US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
CH657779A5 (de) * 1982-10-05 1986-09-30 Sandoz Ag Galenische zusammensetzungen enthaltend calcitonin.
JPH0778017B2 (ja) * 1985-12-28 1995-08-23 住友製薬株式会社 パルス的かつ持続放出性製剤
IT8702928A0 (it) * 1987-07-22 1987-07-22 Alga Di Giudici Angelamaria & Friggitrice con cestello rotante secondo un asse orizzontale.
ATE86484T1 (de) * 1987-08-08 1993-03-15 Akzo Nv Kontrazeptives implantat.
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
JPH07216233A (ja) * 1992-09-21 1995-08-15 Toray Dow Corning Silicone Co Ltd フルオロシリコーンゴム組成物
US6117442A (en) * 1998-11-12 2000-09-12 Leiras Oy Drug delivery device, especially for the delivery of androgens

Also Published As

Publication number Publication date
EP1128811B1 (en) 2004-05-19
AU1048800A (en) 2000-06-05
CN1168439C (zh) 2004-09-29
ID29190A (id) 2001-08-09
DE69917477T2 (de) 2005-06-02
HK1041814A1 (en) 2002-07-26
CZ20011569A3 (cs) 2001-10-17
HU226113B1 (en) 2008-04-28
CA2351068C (en) 2008-09-02
DE69917477D1 (de) 2004-06-24
RU2226387C2 (ru) 2004-04-10
SK5132001A3 (en) 2001-11-06
US6063395A (en) 2000-05-16
AR021152A1 (es) 2002-06-12
BR9915326A (pt) 2001-10-09
ES2221454T3 (es) 2004-12-16
PL194876B1 (pl) 2007-07-31
CN1326337A (zh) 2001-12-12
IL142523A0 (en) 2002-03-10
IL142523A (en) 2006-06-11
BR9915326B1 (pt) 2013-10-22
ATE267004T1 (de) 2004-06-15
NZ511216A (en) 2002-09-27
CA2351068A1 (en) 2000-05-25
NO332168B1 (no) 2012-07-09
KR20010075700A (ko) 2001-08-09
PT1128811E (pt) 2004-09-30
NO20012047D0 (no) 2001-04-26
ZA200103298B (en) 2001-10-25
HUP0104037A3 (en) 2003-04-28
SK286730B6 (sk) 2009-04-06
WO2000028968A1 (en) 2000-05-25
JP2002529493A (ja) 2002-09-10
KR100621426B1 (ko) 2006-09-13
BG65042B1 (bg) 2007-01-31
BG105501A (en) 2001-12-29
HUP0104037A2 (hu) 2002-04-29
NO20012047L (no) 2001-06-28
CZ301609B6 (cs) 2010-04-28
PL348113A1 (en) 2002-05-06
AU760302B2 (en) 2003-05-08
PE20001041A1 (es) 2000-10-14
EE200100256A (et) 2002-12-16
HK1041814B (zh) 2005-04-29
DK1128811T3 (da) 2004-09-27
EE05506B1 (et) 2012-02-15
EP1128811A1 (en) 2001-09-05

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